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The map label for this gene is cutS [H]

Identifier: 226950264

GI number: 226950264

Start: 3245205

End: 3245693

Strand: Reverse

Name: cutS [H]

Synonym: CLM_3221

Alternate gene names: 226950264

Gene position: 3245693-3245205 (Counterclockwise)

Preceding gene: 226950265

Following gene: 226950263

Centisome position: 78.11

GC content: 35.58

Gene sequence:

>489_bases
ATGATGAAGGTATTGGGTAAAACAATAATAACCTTAAATATAAATGGGGAATATAAAGAAGTTGTGGCAAAACCCTCAGA
CATTTTACTGCACACCCTTCGAAATGAACTAGGACTTACGGGGGCTAAGCCATCTTGTGAAAATGGAGACTGTGGTGCAT
GTACTATTCTTGTAGATGGATGGCCTATAAAATCTTGTCTAATGCTAACAGTTGAGGCCATAGGCAAAAAAATAGTCACT
GTTGAAGGCTTGAAAAATGCACCAATACAAAAAGCTTTTGTGGATAACTGGGGGTTTCAATGTGGATATTGTACCTCAGG
ATTTTTGATGGTTTGTCATGCTTTAGCAAATATACATCCCAATGCAGATGACTATGTAATAGAACAATGGTTGCAATCAA
ATCTTTGCCGATGTACTGGTTATGAAGAAATAAAAGATGCAATCAAATCAGTTATATCAGATAACCAATCTGAAAATAAC
AGTATATAA

Upstream 100 bases:

>100_bases
GATGTAATATTAAATGATTTAGCTGGATCTGCTAGTTTTAGAAAGTTTATGTTACAAAAAATGCTCGCAGAAGTTTTAGA
AAAACTGGAGGGATAAGTAA

Downstream 100 bases:

>100_bases
TGGGACTAAAAGGCTTAATTAAGAAGAGAATATACAAAAAAGAAGGCATATTTATTTATAGGCTTTCTTTTTTTATTCAC
CAACACAGAATATTCGGTAC

Product: xanthine dehydrogenase family protein iron-sulfur binding subunit

Products: NA

Alternate protein names: CO dehydrogenase subunit S; CO-DH S [H]

Number of amino acids: Translated: 162; Mature: 162

Protein sequence:

>162_residues
MMKVLGKTIITLNINGEYKEVVAKPSDILLHTLRNELGLTGAKPSCENGDCGACTILVDGWPIKSCLMLTVEAIGKKIVT
VEGLKNAPIQKAFVDNWGFQCGYCTSGFLMVCHALANIHPNADDYVIEQWLQSNLCRCTGYEEIKDAIKSVISDNQSENN
SI

Sequences:

>Translated_162_residues
MMKVLGKTIITLNINGEYKEVVAKPSDILLHTLRNELGLTGAKPSCENGDCGACTILVDGWPIKSCLMLTVEAIGKKIVT
VEGLKNAPIQKAFVDNWGFQCGYCTSGFLMVCHALANIHPNADDYVIEQWLQSNLCRCTGYEEIKDAIKSVISDNQSENN
SI
>Mature_162_residues
MMKVLGKTIITLNINGEYKEVVAKPSDILLHTLRNELGLTGAKPSCENGDCGACTILVDGWPIKSCLMLTVEAIGKKIVT
VEGLKNAPIQKAFVDNWGFQCGYCTSGFLMVCHALANIHPNADDYVIEQWLQSNLCRCTGYEEIKDAIKSVISDNQSENN
SI

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=143, Percent_Identity=33.5664335664336, Blast_Score=67, Evalue=8e-12,
Organism=Homo sapiens, GI71773480, Length=180, Percent_Identity=32.2222222222222, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1786480, Length=169, Percent_Identity=35.5029585798817, Blast_Score=104, Evalue=2e-24,
Organism=Escherichia coli, GI1789232, Length=146, Percent_Identity=40.4109589041096, Blast_Score=92, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17539860, Length=158, Percent_Identity=37.3417721518987, Blast_Score=102, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI17540638, Length=162, Percent_Identity=38.8888888888889, Blast_Score=100, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI32566215, Length=163, Percent_Identity=35.5828220858896, Blast_Score=100, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24647197, Length=168, Percent_Identity=38.0952380952381, Blast_Score=89, Evalue=9e-19,
Organism=Drosophila melanogaster, GI24647195, Length=168, Percent_Identity=38.0952380952381, Blast_Score=89, Evalue=9e-19,
Organism=Drosophila melanogaster, GI24647201, Length=161, Percent_Identity=39.1304347826087, Blast_Score=87, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24647199, Length=142, Percent_Identity=40.1408450704225, Blast_Score=87, Evalue=6e-18,
Organism=Drosophila melanogaster, GI17737937, Length=162, Percent_Identity=32.0987654320988, Blast_Score=87, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24647193, Length=165, Percent_Identity=36.3636363636364, Blast_Score=84, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 17725; Mature: 17725

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
8.0 %Cys+Met (Translated Protein)
5.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
8.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKVLGKTIITLNINGEYKEVVAKPSDILLHTLRNELGLTGAKPSCENGDCGACTILVDG
CCCCCCCEEEEEEECCHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECC
WPIKSCLMLTVEAIGKKIVTVEGLKNAPIQKAFVDNWGFQCGYCTSGFLMVCHALANIHP
CCHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCC
NADDYVIEQWLQSNLCRCTGYEEIKDAIKSVISDNQSENNSI
CCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MMKVLGKTIITLNINGEYKEVVAKPSDILLHTLRNELGLTGAKPSCENGDCGACTILVDG
CCCCCCCEEEEEEECCHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECC
WPIKSCLMLTVEAIGKKIVTVEGLKNAPIQKAFVDNWGFQCGYCTSGFLMVCHALANIHP
CCHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCC
NADDYVIEQWLQSNLCRCTGYEEIKDAIKSVISDNQSENNSI
CCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]