Click here to switch to the map view.

The map label for this gene is atoD [H]

Identifier: 226950261

GI number: 226950261

Start: 3242454

End: 3243170

Strand: Direct

Name: atoD [H]

Synonym: CLM_3218

Alternate gene names: 226950261

Gene position: 3242454-3243170 (Clockwise)

Preceding gene: 226950260

Following gene: 226950262

Centisome position: 78.03

GC content: 34.87

Gene sequence:

>717_bases
ATGACAAAGATTAAGACAATACAAGAAGCAGTAGAAAATATTAAAGATGGAATGAAAATTATGGCAGCAGGTTTTTTAGG
AGTAGGTGCTCCACTAAAGATGATAGATGCATTAGCAGAGACAAATGTTAAAGACCTTACACTTATTCAACCTGTATCAG
CTCACCCAGGACAAACTCACGATATTGGCAAGCTTGTAGCAAATAAACAAATAAAAAAGTTTGTAGGTTCACATATTGGA
ACTTGCCCTGAAATACAAGAACAATACAATGCAGGTACATTAGAAGTTGAATTTATACCTATGGGAACTATAGTAGAATG
TATAAGAGCTGGTGGAGCTGGACTTGGTGCAGTTGTAACTCCAACTGGTATTGGAACTGAAATTGAAAAGGGAAGAGATA
AACTTACTATAGATGGAAAGGAATATTTAGTATTTCCACCAATAAAGGCAGATGTTGCGATAATCAAGGGGTATAAAGCT
GATAAACTTGGGAATATCGTATATAGAGGAACAACTAAAGGAGCAAATACAAGTATGGCACTTGCAGCTGATTTAGTTAT
AGCTGAAGTAGATGAAATTGTAGAAGTGGGTGAAATTTCACCTGATAGTATTGGAACACCAGGAATATTGGTAGATATAA
TAGTTCAAGGAGACTCTTTTGGAGAGAGAAAAAAATATTTTGAAGATTTATGGGTAGCAACTAACAAAATGAAATAG

Upstream 100 bases:

>100_bases
AGGAATAATAATAATGTAAGAATTAAATTTCTAATATAGAGGTATTATTCAAAAAAAATAGTCCATGTTAGATTATAGAA
CTTTGGAGGTATATAGAAAA

Downstream 100 bases:

>100_bases
GGGGAGAAATGATGAATAGTAAAGAGATAATTGCAAGAAGAATCGCGAAAGAGTTTAAAGAGGGAATGGTTGCTAATTTA
GGATTCGGTATACCCAATAT

Product: CoA-transferase subunit A

Products: NA

Alternate protein names: Acetyl-CoA:acetoacetate-CoA transferase subunit alpha [H]

Number of amino acids: Translated: 238; Mature: 237

Protein sequence:

>238_residues
MTKIKTIQEAVENIKDGMKIMAAGFLGVGAPLKMIDALAETNVKDLTLIQPVSAHPGQTHDIGKLVANKQIKKFVGSHIG
TCPEIQEQYNAGTLEVEFIPMGTIVECIRAGGAGLGAVVTPTGIGTEIEKGRDKLTIDGKEYLVFPPIKADVAIIKGYKA
DKLGNIVYRGTTKGANTSMALAADLVIAEVDEIVEVGEISPDSIGTPGILVDIIVQGDSFGERKKYFEDLWVATNKMK

Sequences:

>Translated_238_residues
MTKIKTIQEAVENIKDGMKIMAAGFLGVGAPLKMIDALAETNVKDLTLIQPVSAHPGQTHDIGKLVANKQIKKFVGSHIG
TCPEIQEQYNAGTLEVEFIPMGTIVECIRAGGAGLGAVVTPTGIGTEIEKGRDKLTIDGKEYLVFPPIKADVAIIKGYKA
DKLGNIVYRGTTKGANTSMALAADLVIAEVDEIVEVGEISPDSIGTPGILVDIIVQGDSFGERKKYFEDLWVATNKMK
>Mature_237_residues
TKIKTIQEAVENIKDGMKIMAAGFLGVGAPLKMIDALAETNVKDLTLIQPVSAHPGQTHDIGKLVANKQIKKFVGSHIGT
CPEIQEQYNAGTLEVEFIPMGTIVECIRAGGAGLGAVVTPTGIGTEIEKGRDKLTIDGKEYLVFPPIKADVAIIKGYKAD
KLGNIVYRGTTKGANTSMALAADLVIAEVDEIVEVGEISPDSIGTPGILVDIIVQGDSFGERKKYFEDLWVATNKMK

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=234, Percent_Identity=37.1794871794872, Blast_Score=155, Evalue=4e-38,
Organism=Homo sapiens, GI11545841, Length=234, Percent_Identity=39.3162393162393, Blast_Score=145, Evalue=4e-35,
Organism=Escherichia coli, GI1788551, Length=219, Percent_Identity=45.2054794520548, Blast_Score=202, Evalue=2e-53,
Organism=Escherichia coli, GI1787985, Length=238, Percent_Identity=24.7899159663866, Blast_Score=60, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI17531517, Length=238, Percent_Identity=35.7142857142857, Blast_Score=139, Evalue=1e-33,
Organism=Drosophila melanogaster, GI21358325, Length=235, Percent_Identity=37.4468085106383, Blast_Score=149, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24655794, Length=235, Percent_Identity=37.4468085106383, Blast_Score=149, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.8 [H]

Molecular weight: Translated: 25367; Mature: 25236

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKIKTIQEAVENIKDGMKIMAAGFLGVGAPLKMIDALAETNVKDLTLIQPVSAHPGQTH
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCH
DIGKLVANKQIKKFVGSHIGTCPEIQEQYNAGTLEVEFIPMGTIVECIRAGGAGLGAVVT
HHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEEEEEEECHHHHHHHHHCCCCCCCEEEC
PTGIGTEIEKGRDKLTIDGKEYLVFPPIKADVAIIKGYKADKLGNIVYRGTTKGANTSMA
CCCCCCHHHCCCCEEEECCCEEEEECCCCCCCCEECCCCCCCCCCEEEECCCCCCCCHHH
LAADLVIAEVDEIVEVGEISPDSIGTPGILVDIIVQGDSFGERKKYFEDLWVATNKMK
HHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TKIKTIQEAVENIKDGMKIMAAGFLGVGAPLKMIDALAETNVKDLTLIQPVSAHPGQTH
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCH
DIGKLVANKQIKKFVGSHIGTCPEIQEQYNAGTLEVEFIPMGTIVECIRAGGAGLGAVVT
HHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEEEEEEECHHHHHHHHHCCCCCCCEEEC
PTGIGTEIEKGRDKLTIDGKEYLVFPPIKADVAIIKGYKADKLGNIVYRGTTKGANTSMA
CCCCCCHHHCCCCEEEECCCEEEEECCCCCCCCEECCCCCCCCCCEEEECCCCCCCCHHH
LAADLVIAEVDEIVEVGEISPDSIGTPGILVDIIVQGDSFGERKKYFEDLWVATNKMK
HHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]