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The map label for this gene is insK [H]

Identifier: 226950256

GI number: 226950256

Start: 3237112

End: 3237777

Strand: Reverse

Name: insK [H]

Synonym: CLM_3211

Alternate gene names: 226950256

Gene position: 3237777-3237112 (Counterclockwise)

Preceding gene: 226950257

Following gene: 226950255

Centisome position: 77.92

GC content: 32.88

Gene sequence:

>666_bases
ATGACAATCAAGTTAAATCGTGAGCATGAGTTTCATGTAAATTCGAAAAGAATTTACAGACTTATGTCAATTCTGAATTT
AAAATCTGTTTGTCGTAAGAAGAAAAAGAATTACAAGAAAACAACACCACAAGTAACAGCAGAAAATACTTTAAATAGGA
ATTTTAATTCTGATAAATTCGGGGAGAAATGGCTTACAGATGTAACTGAGATGAAGTACGGAATTGGAGGCAAGGCTTAT
CTAAGTGCCATATTAGACCTTGCTGACAAAAGCATTGTATCATTTGTAATTGGTCATTCTAATAATAATACTCTTGTTTT
TAAAACATTTGATATAACTCATGAGCAGCATCCTGACGCAAAGCCTCTGTTTCACAGTGACGGAGGCTTTCAATATACCT
CTAAAAATTTTAAGAAAAAGTTAGATGATGCAGATATGACTCAAAGCATGTCAAGGGTATCACGTTGTATCGACAACGGT
CCGATGGAAGCATTCTGGGGCATGTTAAAATCTGAAATGTATTACTTGAGAAAGTTCAATTCATATAGTGAACTAGAAAG
TGTAATCACTGATTATATAAATTATTACAACAATCAAAGATATCAGAAGCGTCTAAAATGTATGACACCTTTAGAATATC
GAGAGTATCTGAAATCTGTAGCATAA

Upstream 100 bases:

>100_bases
AAATCGTAACGAAAGTAGCAACGAACAATTCAATCAAGAATTACTGCCGCTAATAAAAAATGCTTATGAGGAAAAACAAG
GAATATTAGGATATAGACAA

Downstream 100 bases:

>100_bases
AATACCGCCAACTACAAAAGTAATTGCCGGTATCAAATATTTTTATTTTTTTCACTGTCTACTTGACAGGGAGCAGTTCA
TTTATCAACAGCCTGAAGGT

Product: transposase ISLasa6a, IS3 family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 221; Mature: 220

Protein sequence:

>221_residues
MTIKLNREHEFHVNSKRIYRLMSILNLKSVCRKKKKNYKKTTPQVTAENTLNRNFNSDKFGEKWLTDVTEMKYGIGGKAY
LSAILDLADKSIVSFVIGHSNNNTLVFKTFDITHEQHPDAKPLFHSDGGFQYTSKNFKKKLDDADMTQSMSRVSRCIDNG
PMEAFWGMLKSEMYYLRKFNSYSELESVITDYINYYNNQRYQKRLKCMTPLEYREYLKSVA

Sequences:

>Translated_221_residues
MTIKLNREHEFHVNSKRIYRLMSILNLKSVCRKKKKNYKKTTPQVTAENTLNRNFNSDKFGEKWLTDVTEMKYGIGGKAY
LSAILDLADKSIVSFVIGHSNNNTLVFKTFDITHEQHPDAKPLFHSDGGFQYTSKNFKKKLDDADMTQSMSRVSRCIDNG
PMEAFWGMLKSEMYYLRKFNSYSELESVITDYINYYNNQRYQKRLKCMTPLEYREYLKSVA
>Mature_220_residues
TIKLNREHEFHVNSKRIYRLMSILNLKSVCRKKKKNYKKTTPQVTAENTLNRNFNSDKFGEKWLTDVTEMKYGIGGKAYL
SAILDLADKSIVSFVIGHSNNNTLVFKTFDITHEQHPDAKPLFHSDGGFQYTSKNFKKKLDDADMTQSMSRVSRCIDNGP
MEAFWGMLKSEMYYLRKFNSYSELESVITDYINYYNNQRYQKRLKCMTPLEYREYLKSVA

Specific function: Involved in the transposition of the insertion sequence IS150 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=172, Percent_Identity=26.7441860465116, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1789981, Length=216, Percent_Identity=38.4259259259259, Blast_Score=153, Evalue=9e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 25992; Mature: 25861

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIKLNREHEFHVNSKRIYRLMSILNLKSVCRKKKKNYKKTTPQVTAENTLNRNFNSDKF
CEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCHH
GEKWLTDVTEMKYGIGGKAYLSAILDLADKSIVSFVIGHSNNNTLVFKTFDITHEQHPDA
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCC
KPLFHSDGGFQYTSKNFKKKLDDADMTQSMSRVSRCIDNGPMEAFWGMLKSEMYYLRKFN
CCCEECCCCCEEHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCC
SYSELESVITDYINYYNNQRYQKRLKCMTPLEYREYLKSVA
CHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHCC
>Mature Secondary Structure 
TIKLNREHEFHVNSKRIYRLMSILNLKSVCRKKKKNYKKTTPQVTAENTLNRNFNSDKF
EEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCHH
GEKWLTDVTEMKYGIGGKAYLSAILDLADKSIVSFVIGHSNNNTLVFKTFDITHEQHPDA
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCC
KPLFHSDGGFQYTSKNFKKKLDDADMTQSMSRVSRCIDNGPMEAFWGMLKSEMYYLRKFN
CCCEECCCCCEEHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCC
SYSELESVITDYINYYNNQRYQKRLKCMTPLEYREYLKSVA
CHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2841644; 2541046; 8041620; 9278503 [H]