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The map label for this gene is pyrK [H]

Identifier: 226949642

GI number: 226949642

Start: 2613606

End: 2614307

Strand: Direct

Name: pyrK [H]

Synonym: CLM_2579

Alternate gene names: 226949642

Gene position: 2613606-2614307 (Clockwise)

Preceding gene: 226949641

Following gene: 226949657

Centisome position: 62.9

GC content: 28.77

Gene sequence:

>702_bases
TTGGTTTATCCAGGCAGTTTTGTATTTTTAAGAAACAAAAATGACTCTGGTTTTTATGATGCTCCTATTTCTATTATGGA
TGTAGATACAGAAGAAAACTTTATTAAGGTCGCTATTGAAATTAGAGGTGTAAAAACTAAGACCATAGCTAGTTTAAATA
AAAATGATGATATTTGGGTAAGGGGTCCTTTCTGGAATGGGGTCTTAGGTCTCAAAAATGTTTATATGACAAAAGATGGA
ACTAGCCTTTTAATATCAAGAGGCATAGGTCAAGCGCCTTTAGTTCCTGTTATGAAAAAATTATACTCTAACGGAAATAA
GATAATAGCTATAATAGATAATTCTGGTTATGAAAATATATTGATAAAAAATTACTTAGAATTATACAATGCAGAGGTTA
TAGAATTAAATACTTTAAAAGCTGGTGAGCTTACAGAGGAATTAAAAGACAAATTAAAAGAAATCCTAGATAAAGAAGAT
ATTAATATAATTCATTGTTCTGCTCAAGATATTATAATATATAAACTTGTCGAATTTTTAGATGGGAAAGTGCCAATATC
TAGTTCTAATAATGCAAAAATGTGTTGTGGTGAAGGAGTTTGTGGTACTTGTACTGTAAGATATAAAGGTCATATAGTTA
AAAGACTATGTAAGATTCAAACGGAACCTAAATATGTATTTAGAGAAAGAAGACTTATTTAA

Upstream 100 bases:

>100_bases
GGAAAGAGAAACTTACTTAGGTAAAATTATAAAAAAAGATAACATAGAGGATAAAACCATAGTGCTAACCATATCATTAA
GCCATAAATTGTGTCAACAG

Downstream 100 bases:

>100_bases
ACTTTAGAAAAACCCCAGGTATTTCTACCTGGGGCCCTTTGAATAACTTAAGCATTAAAAAATCTAATACTTTTCTTCTT
TAGTGTGCTAATACTTAGTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MVYPGSFVFLRNKNDSGFYDAPISIMDVDTEENFIKVAIEIRGVKTKTIASLNKNDDIWVRGPFWNGVLGLKNVYMTKDG
TSLLISRGIGQAPLVPVMKKLYSNGNKIIAIIDNSGYENILIKNYLELYNAEVIELNTLKAGELTEELKDKLKEILDKED
INIIHCSAQDIIIYKLVEFLDGKVPISSSNNAKMCCGEGVCGTCTVRYKGHIVKRLCKIQTEPKYVFRERRLI

Sequences:

>Translated_233_residues
MVYPGSFVFLRNKNDSGFYDAPISIMDVDTEENFIKVAIEIRGVKTKTIASLNKNDDIWVRGPFWNGVLGLKNVYMTKDG
TSLLISRGIGQAPLVPVMKKLYSNGNKIIAIIDNSGYENILIKNYLELYNAEVIELNTLKAGELTEELKDKLKEILDKED
INIIHCSAQDIIIYKLVEFLDGKVPISSSNNAKMCCGEGVCGTCTVRYKGHIVKRLCKIQTEPKYVFRERRLI
>Mature_233_residues
MVYPGSFVFLRNKNDSGFYDAPISIMDVDTEENFIKVAIEIRGVKTKTIASLNKNDDIWVRGPFWNGVLGLKNVYMTKDG
TSLLISRGIGQAPLVPVMKKLYSNGNKIIAIIDNSGYENILIKNYLELYNAEVIELNTLKAGELTEELKDKLKEILDKED
INIIHCSAQDIIIYKLVEFLDGKVPISSSNNAKMCCGEGVCGTCTVRYKGHIVKRLCKIQTEPKYVFRERRLI

Specific function: Is responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the pyrD subunit to the ultimate electron acceptor NAD(+) [H]

COG id: COG0543

COG function: function code HC; 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012165
- InterPro:   IPR019480
- InterPro:   IPR017927
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR000951
- InterPro:   IPR017938 [H]

Pfam domain/function: PF10418 DHODB_Fe-S_bind; PF00970 FAD_binding_6; PF00175 NAD_binding_1 [H]

EC number: NA

Molecular weight: Translated: 26304; Mature: 26304

Theoretical pI: Translated: 8.33; Mature: 8.33

Prosite motif: PS00197 2FE2S_FER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVYPGSFVFLRNKNDSGFYDAPISIMDVDTEENFIKVAIEIRGVKTKTIASLNKNDDIWV
CCCCCCEEEEEECCCCCEEECCEEEEEECCCCCEEEEEEEEECCCEEEEEECCCCCCEEE
RGPFWNGVLGLKNVYMTKDGTSLLISRGIGQAPLVPVMKKLYSNGNKIIAIIDNSGYENI
ECCCCCCCCCCCEEEEECCCCEEEEECCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCHH
LIKNYLELYNAEVIELNTLKAGELTEELKDKLKEILDKEDINIIHCSAQDIIIYKLVEFL
HHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHH
DGKVPISSSNNAKMCCGEGVCGTCTVRYKGHIVKRLCKIQTEPKYVFRERRLI
CCCCCCCCCCCCEEEECCCCCEEEEEEECHHHHHHHHHCCCCCHHHHHHCCCC
>Mature Secondary Structure
MVYPGSFVFLRNKNDSGFYDAPISIMDVDTEENFIKVAIEIRGVKTKTIASLNKNDDIWV
CCCCCCEEEEEECCCCCEEECCEEEEEECCCCCEEEEEEEEECCCEEEEEECCCCCCEEE
RGPFWNGVLGLKNVYMTKDGTSLLISRGIGQAPLVPVMKKLYSNGNKIIAIIDNSGYENI
ECCCCCCCCCCCEEEEECCCCEEEEECCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCHH
LIKNYLELYNAEVIELNTLKAGELTEELKDKLKEILDKEDINIIHCSAQDIIIYKLVEFL
HHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHH
DGKVPISSSNNAKMCCGEGVCGTCTVRYKGHIVKRLCKIQTEPKYVFRERRLI
CCCCCCCCCCCCEEEECCCCCEEEEEEECHHHHHHHHHCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014 [H]