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The map label for this gene is pepQ [C]

Identifier: 226949324

GI number: 226949324

Start: 2314392

End: 2315480

Strand: Direct

Name: pepQ [C]

Synonym: CLM_2245

Alternate gene names: 226949324

Gene position: 2314392-2315480 (Clockwise)

Preceding gene: 226949311

Following gene: 226949325

Centisome position: 55.7

GC content: 32.97

Gene sequence:

>1089_bases
ATGGATATAAATAAACTGAACAGAGTATTAAAATCTATGAAAGAACATGACATTCCACAAATGATTATATCTGATCCCAC
AGCTATTTTTTATTTAACAGGAAAATGGATTATTCCAGGAGAAAGATTATTAGCATTATACTTAAATGTTAATGGAAATC
ACAAAATTGTTATTAATGAACTGTTCCCACAAGAAGAAGATCTTGGTGTAGAAATCGTATGGTACAACGATATTCAAGAC
GGAGTTGAAATCTTATCTAAATTTGTAGAAAAAGATAAAGTTATAGGTATCGATAAAGTATGGCCATCTAAATTCTTATT
AAGATTACAAGAACTTGGGGGCGGAAGTAAATTTGTAAACGGTTCCTTTATTGTTGACTATGTAAGAATGATTAAAGACG
AAGAAGAAATCGCTATTTTGAGAGAATCTTCAAGATTAAATGACCTTGTAATTGATGAATTGATTCCATGGGTAGGAAAA
GGTTTATCTGAAAAAGAATTAAATACTAAGGTTCGTGAAATTTACAAAAAACATGGTATTAATGAAGTATCTTTCGACCC
TATTACAGCATATGCTAAGGGAGCAGCAGATCCACACCATGTAACAGATGATACAAAAGGAAAATATGGTGACTGCGTTA
TCCTTGATATTGGAGGATTCTACAAAAACTATGCTTCTGATATGACAAGAACTGTATTTATCGGTGAAGTTTCTGAAAGA
CAAAAAGAAATCTATGACATAGTTGTAGAAGCAAACTTAAGAGGTATTGCTGCTGCAAAACCTGGAAATAGAATGTGTGA
CGTAGACTTAGCTGCAAGAAACTATATTGAAGAAAAAGGATACGGAAAATATTTCACACACAGAACAGGACATTCCTGTG
GTTTGGAAGACCATGAATTCGGTGATGTTTCTTCTGTAAATGAAGATATCATCAAACCAGGACAATGTTTCTCTGTTGAA
CCAGGAATTTACCTTCCTGAAGAAGGAATAGGTGTTCGTATTGAAGACCTTGTTATCACAACTGAAGATGGTTGCGAGGT
ATTAAATAACTATACAAAGGACTTAATTGTTGTTCCTGAATCCAAATAA

Upstream 100 bases:

>100_bases
AAAATAATTTATTGCAATAATTCTAGTATCTTCATTGACATTTGTAGACAAGCATATTATTATATTAGTATTTAATAACT
AAATATAGGAGGGAATACCT

Downstream 100 bases:

>100_bases
AGATAAAGAAATTGGTTAAAAATTTCTATGAAGCTTTTAACAACTAAAACTTATTACAAAATATAGATAAGGAGATCGAT
TATGAAAATTACTGAAGGCT

Product: Xaa-Pro dipeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MDINKLNRVLKSMKEHDIPQMIISDPTAIFYLTGKWIIPGERLLALYLNVNGNHKIVINELFPQEEDLGVEIVWYNDIQD
GVEILSKFVEKDKVIGIDKVWPSKFLLRLQELGGGSKFVNGSFIVDYVRMIKDEEEIAILRESSRLNDLVIDELIPWVGK
GLSEKELNTKVREIYKKHGINEVSFDPITAYAKGAADPHHVTDDTKGKYGDCVILDIGGFYKNYASDMTRTVFIGEVSER
QKEIYDIVVEANLRGIAAAKPGNRMCDVDLAARNYIEEKGYGKYFTHRTGHSCGLEDHEFGDVSSVNEDIIKPGQCFSVE
PGIYLPEEGIGVRIEDLVITTEDGCEVLNNYTKDLIVVPESK

Sequences:

>Translated_362_residues
MDINKLNRVLKSMKEHDIPQMIISDPTAIFYLTGKWIIPGERLLALYLNVNGNHKIVINELFPQEEDLGVEIVWYNDIQD
GVEILSKFVEKDKVIGIDKVWPSKFLLRLQELGGGSKFVNGSFIVDYVRMIKDEEEIAILRESSRLNDLVIDELIPWVGK
GLSEKELNTKVREIYKKHGINEVSFDPITAYAKGAADPHHVTDDTKGKYGDCVILDIGGFYKNYASDMTRTVFIGEVSER
QKEIYDIVVEANLRGIAAAKPGNRMCDVDLAARNYIEEKGYGKYFTHRTGHSCGLEDHEFGDVSSVNEDIIKPGQCFSVE
PGIYLPEEGIGVRIEDLVITTEDGCEVLNNYTKDLIVVPESK
>Mature_362_residues
MDINKLNRVLKSMKEHDIPQMIISDPTAIFYLTGKWIIPGERLLALYLNVNGNHKIVINELFPQEEDLGVEIVWYNDIQD
GVEILSKFVEKDKVIGIDKVWPSKFLLRLQELGGGSKFVNGSFIVDYVRMIKDEEEIAILRESSRLNDLVIDELIPWVGK
GLSEKELNTKVREIYKKHGINEVSFDPITAYAKGAADPHHVTDDTKGKYGDCVILDIGGFYKNYASDMTRTVFIGEVSER
QKEIYDIVVEANLRGIAAAKPGNRMCDVDLAARNYIEEKGYGKYFTHRTGHSCGLEDHEFGDVSSVNEDIIKPGQCFSVE
PGIYLPEEGIGVRIEDLVITTEDGCEVLNNYTKDLIVVPESK

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI11559925, Length=253, Percent_Identity=27.2727272727273, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI149589008, Length=313, Percent_Identity=25.2396166134185, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI260593665, Length=313, Percent_Identity=25.2396166134185, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI93141226, Length=303, Percent_Identity=26.4026402640264, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1788728, Length=241, Percent_Identity=38.5892116182573, Blast_Score=165, Evalue=4e-42,
Organism=Escherichia coli, GI1789275, Length=282, Percent_Identity=28.0141843971631, Blast_Score=116, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17508215, Length=262, Percent_Identity=25.5725190839695, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320922, Length=238, Percent_Identity=23.5294117647059, Blast_Score=69, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6321118, Length=295, Percent_Identity=21.3559322033898, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI19920384, Length=259, Percent_Identity=27.4131274131274, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21355531, Length=247, Percent_Identity=25.1012145748988, Blast_Score=75, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 40837; Mature: 40837

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDINKLNRVLKSMKEHDIPQMIISDPTAIFYLTGKWIIPGERLLALYLNVNGNHKIVINE
CCHHHHHHHHHHHHHCCCCCEECCCCCEEEEEECCEECCCCEEEEEEEEECCCCEEEEEE
LFPQEEDLGVEIVWYNDIQDGVEILSKFVEKDKVIGIDKVWPSKFLLRLQELGGGSKFVN
CCCCCCCCCEEEEEECCHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHCCCCCEEEC
GSFIVDYVRMIKDEEEIAILRESSRLNDLVIDELIPWVGKGLSEKELNTKVREIYKKHGI
CHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCC
NEVSFDPITAYAKGAADPHHVTDDTKGKYGDCVILDIGGFYKNYASDMTRTVFIGEVSER
CCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHCCEEEEEEECHHHH
QKEIYDIVVEANLRGIAAAKPGNRMCDVDLAARNYIEEKGYGKYFTHRTGHSCGLEDHEF
HHHHHHEEEECCCCEEEECCCCCCEEEEHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCC
GDVSSVNEDIIKPGQCFSVEPGIYLPEEGIGVRIEDLVITTEDGCEVLNNYTKDLIVVPE
CCCCCCCHHHCCCCCEEEECCCCCCCCCCCCEEEEEEEEECCCHHHHHHCCCCCEEEEEC
SK
CC
>Mature Secondary Structure
MDINKLNRVLKSMKEHDIPQMIISDPTAIFYLTGKWIIPGERLLALYLNVNGNHKIVINE
CCHHHHHHHHHHHHHCCCCCEECCCCCEEEEEECCEECCCCEEEEEEEEECCCCEEEEEE
LFPQEEDLGVEIVWYNDIQDGVEILSKFVEKDKVIGIDKVWPSKFLLRLQELGGGSKFVN
CCCCCCCCCEEEEEECCHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHCCCCCEEEC
GSFIVDYVRMIKDEEEIAILRESSRLNDLVIDELIPWVGKGLSEKELNTKVREIYKKHGI
CHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCC
NEVSFDPITAYAKGAADPHHVTDDTKGKYGDCVILDIGGFYKNYASDMTRTVFIGEVSER
CCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHCCEEEEEEECHHHH
QKEIYDIVVEANLRGIAAAKPGNRMCDVDLAARNYIEEKGYGKYFTHRTGHSCGLEDHEF
HHHHHHEEEECCCCEEEECCCCCCEEEEHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCC
GDVSSVNEDIIKPGQCFSVEPGIYLPEEGIGVRIEDLVITTEDGCEVLNNYTKDLIVVPE
CCCCCCCHHHCCCCCEEEECCCCCCCCCCCCEEEEEEEEECCCHHHHHHCCCCCEEEEEC
SK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11418146 [H]