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The map label for this gene is dtpA [H]

Identifier: 226949323

GI number: 226949323

Start: 2312537

End: 2313883

Strand: Reverse

Name: dtpA [H]

Synonym: CLM_2244

Alternate gene names: 226949323

Gene position: 2313883-2312537 (Counterclockwise)

Preceding gene: 226949326

Following gene: 226949322

Centisome position: 55.69

GC content: 35.19

Gene sequence:

>1347_bases
ATGGAAAACACAAATAAAAGACCATTTGGGTTCTATGTATGTTCAATTGCTTTCACACTTGAAAGATTTGCATTTTACTC
AGCAAAATGGTTAATAGCAGTATTCGTAATTGCTAAAATAGCGGACGGAGGACTTGGTCTTTCAGCTGCAGATGCAGCAA
AAATGTCTGCAAATTTAGTTGCATTCACTTATCTTGCACCAATAATTGGGGCATTTATATCTGACCGTTTCATAGGGGCT
AGATACCTTGTTCCAATTGGAATGATTTTAATGGGGGCAGGTTATTTAGTAGGATGGCAGGCTTCAAGCGCTGCTATGGT
CAACTTAATGATTGTTTTGGTTTCCATAGGTACAGGTTTATTTAAATGTCAAACAAATGCTATTACAGGTAGGCTTTTCG
ATGATCCAAGAGAATTAGACAGTGCATTCTCTATTCAATATTCTTTTGTTAATATTGGTTCTTTTATCGGTACAACAATT
ATCGGTGTACTTGTAGGGACTAAGGGATATGCTTTCTGTTTCTTAGTTTGCGGAATAATGATGCTTATTGATGCTGCTTG
GTTCATGTTTGGATGGAGATTTTTAGGAGAAACAGGTAAAAAGCCATTTAAAATTGATGAGCATAAAGAAGTGAAAGTAA
AAGAAGTTGAAGAAGAAAAGAAACCACTTACATCAATAGAAAAGAAAAGGGTTGCAGCAATTATATTAGTATCTTTCTTC
TCAGTAATTTTCTGGGTATTCTGGTATTTAGCATATATGCCTGTATATTTCTATTGGGGTGGAGACAATGCAGCGGCTAA
CTGGATGATAGGGAATTTTCAAGTTCCAACAGCTTGGTTTGATTCATTAAATGCATTAGCATGTATCTCATTAGGACCAA
TTCTTGGTAAAGTATGGTCAAAATTAGCTAAGAGACCTCAAGGTGATTTAAGTATGTTTAAGAAAACTGCTTTAGGTATG
ATACTTTTAGGTTTATCCTATGTAATCTTTGCAATGGCAGACGTTACAAGAGGAGGAAATCTTGCACCACTTGCTTGGAT
TATCGCATTCGGTATTGTATTATCTTTAGGTGAAATGGTATTCTCACCACTTGGAAACTCTTTCATTAGTAAATTTTCAC
CACCTAGATTATTATCAAGCATGATGAGTGTTTGGGTACTTGCTGTTTTCTTTGCAGCAAAATCTTATGGATGGGTATAT
GAATTTACACTAAAATTTAAATTCGCACCAACATACTTTGTAATAGCTGCTATTGCTGCTGGAGCAGGTATAATTCTTTG
GTTATTAGATGGAAAATTGAATAGCTTAGTTGTAGAAGAGGAAGAACCATTAAACGAAGCTGTTTAA

Upstream 100 bases:

>100_bases
ATGGTATTTGAAATCATTTCATCTCATCTTGAAAAAGGGGAGAAAATATGGTTTTTGAAATACACACGCAATATTAATCT
TTTTATAGGGGGAATAAAAA

Downstream 100 bases:

>100_bases
TCAATGTAAAAATTTATATTAATATGAAATTTTATAAAATATTTATTTAAAGAAGTCATTGTTTTTCAATGGCTTCTTTT
GTTATAACTTTTTTATTTTT

Product: amino acid/peptide transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MENTNKRPFGFYVCSIAFTLERFAFYSAKWLIAVFVIAKIADGGLGLSAADAAKMSANLVAFTYLAPIIGAFISDRFIGA
RYLVPIGMILMGAGYLVGWQASSAAMVNLMIVLVSIGTGLFKCQTNAITGRLFDDPRELDSAFSIQYSFVNIGSFIGTTI
IGVLVGTKGYAFCFLVCGIMMLIDAAWFMFGWRFLGETGKKPFKIDEHKEVKVKEVEEEKKPLTSIEKKRVAAIILVSFF
SVIFWVFWYLAYMPVYFYWGGDNAAANWMIGNFQVPTAWFDSLNALACISLGPILGKVWSKLAKRPQGDLSMFKKTALGM
ILLGLSYVIFAMADVTRGGNLAPLAWIIAFGIVLSLGEMVFSPLGNSFISKFSPPRLLSSMMSVWVLAVFFAAKSYGWVY
EFTLKFKFAPTYFVIAAIAAGAGIILWLLDGKLNSLVVEEEEPLNEAV

Sequences:

>Translated_448_residues
MENTNKRPFGFYVCSIAFTLERFAFYSAKWLIAVFVIAKIADGGLGLSAADAAKMSANLVAFTYLAPIIGAFISDRFIGA
RYLVPIGMILMGAGYLVGWQASSAAMVNLMIVLVSIGTGLFKCQTNAITGRLFDDPRELDSAFSIQYSFVNIGSFIGTTI
IGVLVGTKGYAFCFLVCGIMMLIDAAWFMFGWRFLGETGKKPFKIDEHKEVKVKEVEEEKKPLTSIEKKRVAAIILVSFF
SVIFWVFWYLAYMPVYFYWGGDNAAANWMIGNFQVPTAWFDSLNALACISLGPILGKVWSKLAKRPQGDLSMFKKTALGM
ILLGLSYVIFAMADVTRGGNLAPLAWIIAFGIVLSLGEMVFSPLGNSFISKFSPPRLLSSMMSVWVLAVFFAAKSYGWVY
EFTLKFKFAPTYFVIAAIAAGAGIILWLLDGKLNSLVVEEEEPLNEAV
>Mature_448_residues
MENTNKRPFGFYVCSIAFTLERFAFYSAKWLIAVFVIAKIADGGLGLSAADAAKMSANLVAFTYLAPIIGAFISDRFIGA
RYLVPIGMILMGAGYLVGWQASSAAMVNLMIVLVSIGTGLFKCQTNAITGRLFDDPRELDSAFSIQYSFVNIGSFIGTTI
IGVLVGTKGYAFCFLVCGIMMLIDAAWFMFGWRFLGETGKKPFKIDEHKEVKVKEVEEEKKPLTSIEKKRVAAIILVSFF
SVIFWVFWYLAYMPVYFYWGGDNAAANWMIGNFQVPTAWFDSLNALACISLGPILGKVWSKLAKRPQGDLSMFKKTALGM
ILLGLSYVIFAMADVTRGGNLAPLAWIIAFGIVLSLGEMVFSPLGNSFISKFSPPRLLSSMMSVWVLAVFFAAKSYGWVY
EFTLKFKFAPTYFVIAAIAAGAGIILWLLDGKLNSLVVEEEEPLNEAV

Specific function: Proton-dependent permease that transports di- and tripeptides [H]

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787922, Length=425, Percent_Identity=24.2352941176471, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI1789911, Length=436, Percent_Identity=23.394495412844, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1786927, Length=433, Percent_Identity=23.094688221709, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1790572, Length=423, Percent_Identity=22.2222222222222, Blast_Score=78, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 49343; Mature: 49343

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCEEEEEECCCCCCEEECCCCCCCCCC
>Mature Secondary Structure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CCCEEEEEECCCCCCEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA