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The map label for this gene is dtpT [H]

Identifier: 226949322

GI number: 226949322

Start: 2310842

End: 2312197

Strand: Reverse

Name: dtpT [H]

Synonym: CLM_2243

Alternate gene names: 226949322

Gene position: 2312197-2310842 (Counterclockwise)

Preceding gene: 226949323

Following gene: 226949321

Centisome position: 55.64

GC content: 33.78

Gene sequence:

>1356_bases
ATGGAACAAAAAAAGAAAATGCCATTTGGGTTTTATATATGTTCAATTTCTTTCTCATTTGAAAGATTTGCATTTTACTC
AGCAAAATGGCTAATTACAGTATTTGTAGCTACCAAAATAGCTAGTGGAGGACTTGGACTTACAGCTGCAGATGCAGCAA
AAATGTCTGCAAATTTAGTTGCATTTACTTATCTTGCACCACTAGTCGGTTCATATATATCTGACCGTAAAGTAGGGGCT
AGATACCTTATTCCTATTGGAATGGTTTTAATGGGATTAGGTTACTTAGTAGGATGGAAGGCTTCAAGTGCTGGTATGAT
TAATTTAATGATTGTATTGGTTTCTATTGGTACAGGCTTATTTAAATCTCAAAACAGTGCTATTACAGGTAGACTTTTTG
ATAATCAAAAAGATTTAGATAATGCATTTTCTATTCAGTATTCTTTTGTTAACATTGGTTCTTTCATAGGTACAACAATT
CTAGGTGTACTTGCAGGAAGCATGGGATACTCTTTCTGTTTTTTAATCTGTGCAATAATGATGTTCCTTGATGCTGCTTG
GTTTGTGTTTGGATGGAGATTCTTAGGAGAGGCTGGTAAAAAACCATTTAAGGTTGATGAACATAAAGAAGTAAAAGCAG
AAAAACAACAAGAAGAAAAGAAGCCTCTTACTACACTAGAAAAGAAAAGAGTTGCAGCTATTATTTTAATATCTTTATTT
TCTATAGTATTTTGGATATTCTGGTTCTTAGCATATATGCCTGTATATTTCTATTGGGGTGGAGATAATGCAGCTGCCAA
TTGGATGATAGGTAACTTCAAGGTACCAACAGCTTGGTTTGATTCTTTAAATGCATTATGCTGTATAACATTAGGACCAA
TCCTTGGTAGAGTTTGGACAAGGTTAGCTAGGAGACCTCAAGGTGATATGAGCATGTTTAAGAAAACTGCTTTAGGTATG
TTACTTCTTGGCTTATCTTATATAATATTTGCAATGGCAGATGTTACAAGAGGAGGACAACTTATATCACTTGGATGGCT
TGTTGTATTTGGTGTAGTATTATCTCTTGGAGAAATGGTGTTCTCACCACTAGGAAATTCATTTATAAGTAAATTTTCTC
CTGCTAAGTTGTTAACAATTATGATGAGCGTTTGGGTATTTTCAAGTTTTGTTGCAGCAAAAGCTTATGGATGGATATAT
GAATTCACATTAAAATTTAAATTTGCACCGGTATACTTTACCGTTGCAGCTATTGCCATTGTATGTGGTGTAATTCTTTG
GGCATTAGATGGAAAATTGAACAGTTTAGTTGTAGACGAGAAAGTTGTGGAAGATAATTCTGTAAACTTAAATTAA

Upstream 100 bases:

>100_bases
TACGGTATTAGAAGCCGTTGTACACCATTTTAATAAATATGAATGTACATGGTTTTTCAAATACAAACGCAATATTAATT
TTTATAAAGGGGGAATAAAA

Downstream 100 bases:

>100_bases
AATTCAAGTTTCCAACACTGTATTTTTACAATTATAAGTATTAATATTGTAAATGGAATAATTATTTAATCATTATATGA
AATCCAAAAGGCAGTCATTT

Product: amino acid/peptide transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MEQKKKMPFGFYICSISFSFERFAFYSAKWLITVFVATKIASGGLGLTAADAAKMSANLVAFTYLAPLVGSYISDRKVGA
RYLIPIGMVLMGLGYLVGWKASSAGMINLMIVLVSIGTGLFKSQNSAITGRLFDNQKDLDNAFSIQYSFVNIGSFIGTTI
LGVLAGSMGYSFCFLICAIMMFLDAAWFVFGWRFLGEAGKKPFKVDEHKEVKAEKQQEEKKPLTTLEKKRVAAIILISLF
SIVFWIFWFLAYMPVYFYWGGDNAAANWMIGNFKVPTAWFDSLNALCCITLGPILGRVWTRLARRPQGDMSMFKKTALGM
LLLGLSYIIFAMADVTRGGQLISLGWLVVFGVVLSLGEMVFSPLGNSFISKFSPAKLLTIMMSVWVFSSFVAAKAYGWIY
EFTLKFKFAPVYFTVAAIAIVCGVILWALDGKLNSLVVDEKVVEDNSVNLN

Sequences:

>Translated_451_residues
MEQKKKMPFGFYICSISFSFERFAFYSAKWLITVFVATKIASGGLGLTAADAAKMSANLVAFTYLAPLVGSYISDRKVGA
RYLIPIGMVLMGLGYLVGWKASSAGMINLMIVLVSIGTGLFKSQNSAITGRLFDNQKDLDNAFSIQYSFVNIGSFIGTTI
LGVLAGSMGYSFCFLICAIMMFLDAAWFVFGWRFLGEAGKKPFKVDEHKEVKAEKQQEEKKPLTTLEKKRVAAIILISLF
SIVFWIFWFLAYMPVYFYWGGDNAAANWMIGNFKVPTAWFDSLNALCCITLGPILGRVWTRLARRPQGDMSMFKKTALGM
LLLGLSYIIFAMADVTRGGQLISLGWLVVFGVVLSLGEMVFSPLGNSFISKFSPAKLLTIMMSVWVFSSFVAAKAYGWIY
EFTLKFKFAPVYFTVAAIAIVCGVILWALDGKLNSLVVDEKVVEDNSVNLN
>Mature_451_residues
MEQKKKMPFGFYICSISFSFERFAFYSAKWLITVFVATKIASGGLGLTAADAAKMSANLVAFTYLAPLVGSYISDRKVGA
RYLIPIGMVLMGLGYLVGWKASSAGMINLMIVLVSIGTGLFKSQNSAITGRLFDNQKDLDNAFSIQYSFVNIGSFIGTTI
LGVLAGSMGYSFCFLICAIMMFLDAAWFVFGWRFLGEAGKKPFKVDEHKEVKAEKQQEEKKPLTTLEKKRVAAIILISLF
SIVFWIFWFLAYMPVYFYWGGDNAAANWMIGNFKVPTAWFDSLNALCCITLGPILGRVWTRLARRPQGDMSMFKKTALGM
LLLGLSYIIFAMADVTRGGQLISLGWLVVFGVVLSLGEMVFSPLGNSFISKFSPAKLLTIMMSVWVFSSFVAAKAYGWIY
EFTLKFKFAPVYFTVAAIAIVCGVILWALDGKLNSLVVDEKVVEDNSVNLN

Specific function: Proton-dependent uptake of di- or tri-peptides [H]

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family [H]

Homologues:

Organism=Escherichia coli, GI1787922, Length=425, Percent_Identity=24, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1789911, Length=424, Percent_Identity=23.1132075471698, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1790572, Length=421, Percent_Identity=23.2779097387173, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1786927, Length=438, Percent_Identity=21.0045662100457, Blast_Score=75, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 49939; Mature: 49939

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: PS00211 ABC_TRANSPORTER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQKKKMPFGFYICSISFSFERFAFYSAKWLITVFVATKIASGGLGLTAADAAKMSANLV
CCCCCCCCCEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
AFTYLAPLVGSYISDRKVGARYLIPIGMVLMGLGYLVGWKASSAGMINLMIVLVSIGTGL
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCH
FKSQNSAITGRLFDNQKDLDNAFSIQYSFVNIGSFIGTTILGVLAGSMGYSFCFLICAIM
HCCCCCCEEEEECCCCCCCCCHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MFLDAAWFVFGWRFLGEAGKKPFKVDEHKEVKAEKQQEEKKPLTTLEKKRVAAIILISLF
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
SIVFWIFWFLAYMPVYFYWGGDNAAANWMIGNFKVPTAWFDSLNALCCITLGPILGRVWT
HHHHHHHHHHHHHHEEEEECCCCCCCCEEECCEECCHHHHHCCCHHHHHHHHHHHHHHHH
RLARRPQGDMSMFKKTALGMLLLGLSYIIFAMADVTRGGQLISLGWLVVFGVVLSLGEMV
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHH
FSPLGNSFISKFSPAKLLTIMMSVWVFSSFVAAKAYGWIYEFTLKFKFAPVYFTVAAIAI
HHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEECHHHHHHHHHHH
VCGVILWALDGKLNSLVVDEKVVEDNSVNLN
HHHHHHHHHCCCHHHEEECHHHHCCCCCCCC
>Mature Secondary Structure
MEQKKKMPFGFYICSISFSFERFAFYSAKWLITVFVATKIASGGLGLTAADAAKMSANLV
CCCCCCCCCEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
AFTYLAPLVGSYISDRKVGARYLIPIGMVLMGLGYLVGWKASSAGMINLMIVLVSIGTGL
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCH
FKSQNSAITGRLFDNQKDLDNAFSIQYSFVNIGSFIGTTILGVLAGSMGYSFCFLICAIM
HCCCCCCEEEEECCCCCCCCCHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MFLDAAWFVFGWRFLGEAGKKPFKVDEHKEVKAEKQQEEKKPLTTLEKKRVAAIILISLF
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
SIVFWIFWFLAYMPVYFYWGGDNAAANWMIGNFKVPTAWFDSLNALCCITLGPILGRVWT
HHHHHHHHHHHHHHEEEEECCCCCCCCEEECCEECCHHHHHCCCHHHHHHHHHHHHHHHH
RLARRPQGDMSMFKKTALGMLLLGLSYIIFAMADVTRGGQLISLGWLVVFGVVLSLGEMV
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHH
FSPLGNSFISKFSPAKLLTIMMSVWVFSSFVAAKAYGWIYEFTLKFKFAPVYFTVAAIAI
HHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEECHHHHHHHHHHH
VCGVILWALDGKLNSLVVDEKVVEDNSVNLN
HHHHHHHHHCCCHHHEEECHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]