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The map label for this gene is metA [H]

Identifier: 226949172

GI number: 226949172

Start: 2147430

End: 2148326

Strand: Reverse

Name: metA [H]

Synonym: CLM_2090

Alternate gene names: 226949172

Gene position: 2148326-2147430 (Counterclockwise)

Preceding gene: 226949173

Following gene: 226949171

Centisome position: 51.7

GC content: 24.53

Gene sequence:

>897_bases
ATGGCTTTAATCATAGATAAAAACCTTCCAGCTTACCAAATATTAAAATCTGAAAATATAAATATAATGGATAAATTAAA
TTATAACAAAAATACAAATAAATTAAAACTTATAATATTAAACTTGATGCCTAAAAAAATAGAGGCGGAAACACAAATAC
TAAGAGTCTTAGGCAAAAGTTTTATAGATTTAGAGATTACTTTTTTAAAAACTGAAAGTTATAAGAGTAAAAATGTAAGC
AATGATCATTTAAATAAATTTTATAAGACTTTTAGTGAAATAAAAAATCATAATTTTCATGGAATGATTATAACCGGTGC
TCCAGTAGAACTTATGGATTTTGAAAGAGTAGATTATTGGGAAGAACTTAAAAATATAATGGATTATTGTAATAAAAAAG
TAAAATCTACTATATTCATATGTTGGGCAGCTCAAGCAGCCTTATACTACTATTATGATATAAATAAGTATTCATTAAAT
AAAAAGCTTTTTGGTGTGTTTCCTCATAAAATAAGTAAAGGAAATTCTTTACTTACTAAAGGTTTTGATGATGAATTTTA
TGTACCCCATTCCAGGTATACTTATACAAGAAAAGAAGATATAAAAAGATGCAAAGATATAGAGATAATTTCCGAATCAG
AAGAAGCAGGATTATATTTAATGCAAAGCAATAATTTTAAAAAAATATTTATATCAGGACACTGTGAATATGACAGGTAT
ACATTATATGAAGAATATATTAGAGATATAAATAAGAATAAGCATATAGACATTCCTAAAAACTATTTTAAAGAAAATAA
TTTAAACAAAAAACCTATAATGAGATGGCGTTGTCATGGAGAAACCTTGTTTTTAAATTGGATACAGTTGCTAGAAAAGT
TATCAAGTGATTCTTAG

Upstream 100 bases:

>100_bases
ATTTAAAAGATAAGCTGGATAGTATACCTAATATTAAAAAATTAAGGGCTACTATAATTTTATTCCATAGCTAAGGGCTA
GTTAGCAAAGGAAATAAAAT

Downstream 100 bases:

>100_bases
GTACAAGTAAAGTTTGCTTAGAATAATTAATGTTGGCATAGACAGGATAAAAATTGATATGTATTCATAATATAATAATT
AAATTTACAACAAAAAATGA

Product: homoserine O-succinyltransferase

Products: NA

Alternate protein names: Homoserine O-transsuccinylase; HTS [H]

Number of amino acids: Translated: 298; Mature: 297

Protein sequence:

>298_residues
MALIIDKNLPAYQILKSENINIMDKLNYNKNTNKLKLIILNLMPKKIEAETQILRVLGKSFIDLEITFLKTESYKSKNVS
NDHLNKFYKTFSEIKNHNFHGMIITGAPVELMDFERVDYWEELKNIMDYCNKKVKSTIFICWAAQAALYYYYDINKYSLN
KKLFGVFPHKISKGNSLLTKGFDDEFYVPHSRYTYTRKEDIKRCKDIEIISESEEAGLYLMQSNNFKKIFISGHCEYDRY
TLYEEYIRDINKNKHIDIPKNYFKENNLNKKPIMRWRCHGETLFLNWIQLLEKLSSDS

Sequences:

>Translated_298_residues
MALIIDKNLPAYQILKSENINIMDKLNYNKNTNKLKLIILNLMPKKIEAETQILRVLGKSFIDLEITFLKTESYKSKNVS
NDHLNKFYKTFSEIKNHNFHGMIITGAPVELMDFERVDYWEELKNIMDYCNKKVKSTIFICWAAQAALYYYYDINKYSLN
KKLFGVFPHKISKGNSLLTKGFDDEFYVPHSRYTYTRKEDIKRCKDIEIISESEEAGLYLMQSNNFKKIFISGHCEYDRY
TLYEEYIRDINKNKHIDIPKNYFKENNLNKKPIMRWRCHGETLFLNWIQLLEKLSSDS
>Mature_297_residues
ALIIDKNLPAYQILKSENINIMDKLNYNKNTNKLKLIILNLMPKKIEAETQILRVLGKSFIDLEITFLKTESYKSKNVSN
DHLNKFYKTFSEIKNHNFHGMIITGAPVELMDFERVDYWEELKNIMDYCNKKVKSTIFICWAAQAALYYYYDINKYSLNK
KLFGVFPHKISKGNSLLTKGFDDEFYVPHSRYTYTRKEDIKRCKDIEIISESEEAGLYLMQSNNFKKIFISGHCEYDRYT
LYEEYIRDINKNKHIDIPKNYFKENNLNKKPIMRWRCHGETLFLNWIQLLEKLSSDS

Specific function: Methionine biosynthesis; HTS variant; first step. [C]

COG id: COG1897

COG function: function code E; Homoserine trans-succinylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HTS family [H]

Homologues:

Organism=Escherichia coli, GI1790443, Length=289, Percent_Identity=41.8685121107266, Blast_Score=257, Evalue=5e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005697
- ProDom:   PD037892 [H]

Pfam domain/function: PF04204 HTS [H]

EC number: =2.3.1.46 [H]

Molecular weight: Translated: 35545; Mature: 35414

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALIIDKNLPAYQILKSENINIMDKLNYNKNTNKLKLIILNLMPKKIEAETQILRVLGKS
CEEEEECCCCHHHHHCCCCCCEEEECCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHCCC
FIDLEITFLKTESYKSKNVSNDHLNKFYKTFSEIKNHNFHGMIITGAPVELMDFERVDYW
CEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCEEECCCHHCHHH
EELKNIMDYCNKKVKSTIFICWAAQAALYYYYDINKYSLNKKLFGVFPHKISKGNSLLTK
HHHHHHHHHHCHHHHHEEEEEEECCEEEEEEEECCEEECCCCEEEECCCCCCCCCCEEEC
GFDDEFYVPHSRYTYTRKEDIKRCKDIEIISESEEAGLYLMQSNNFKKIFISGHCEYDRY
CCCCCEECCCCCEEECCHHHHHHHCCCEEECCCCCCCEEEEECCCEEEEEEECCCCCCHH
TLYEEYIRDINKNKHIDIPKNYFKENNLNKKPIMRWRCHGETLFLNWIQLLEKLSSDS
HHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ALIIDKNLPAYQILKSENINIMDKLNYNKNTNKLKLIILNLMPKKIEAETQILRVLGKS
EEEEECCCCHHHHHCCCCCCEEEECCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHCCC
FIDLEITFLKTESYKSKNVSNDHLNKFYKTFSEIKNHNFHGMIITGAPVELMDFERVDYW
CEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCEEECCCHHCHHH
EELKNIMDYCNKKVKSTIFICWAAQAALYYYYDINKYSLNKKLFGVFPHKISKGNSLLTK
HHHHHHHHHHCHHHHHEEEEEEECCEEEEEEEECCEEECCCCEEEECCCCCCCCCCEEEC
GFDDEFYVPHSRYTYTRKEDIKRCKDIEIISESEEAGLYLMQSNNFKKIFISGHCEYDRY
CCCCCEECCCCCEEECCHHHHHHHCCCEEECCCCCCCEEEEECCCEEEEEEECCCCCCHH
TLYEEYIRDINKNKHIDIPKNYFKENNLNKKPIMRWRCHGETLFLNWIQLLEKLSSDS
HHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA