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The map label for this gene is xerD [H]

Identifier: 226949108

GI number: 226949108

Start: 2093279

End: 2094154

Strand: Reverse

Name: xerD [H]

Synonym: CLM_2026

Alternate gene names: 226949108

Gene position: 2094154-2093279 (Counterclockwise)

Preceding gene: 226949109

Following gene: 226949107

Centisome position: 50.4

GC content: 27.63

Gene sequence:

>876_bases
ATGAAAAATATTATAGAGAATTATATAAAAGATTTACAAAAGAAAAACTTAAGTAAAAATACTTTAGAGGCTTATAGAAG
AGATGTGGAGAAGTTTAGTGAGTTTGTTAGAAACAGAGAGGAAAAAATACTTTCTGTTGATACAGTTACTATAATGGCTT
TCGTTCAATATTTGCAAAGAGAAGGACGAGCTACCTCTTCAATAGTAAGAAATATAGTATCTATAAGAAATTTTTATAAA
TATTTAATTAAAAAAAACATGGTATCTGAGGACCCTACACTAGGATATGAAATACCTAAAATAGAGAGAACTATCCCTAA
AATACTTTCTGTAGAAGAAGTGGATAAACTTTTAAATTCCCCAGATTCTTCAAAAAAGGGATTAAGAGATAAAGCAATGC
TAGAGCTTATGTATGCTACGGGAGTTAAGATTACAGAACTTTTAAATCTAAATATATATGATATAAATTTGAAGTTTAAT
TATATAAAATGTAGAGGCAGTAAAAAAAGAGAGAGAATTATACCTATAGGCTCCTATGCGATAAAGTGTTTAAAGAATTA
TTTAGAAGTAAGACCAGCTATAAATGTATATAATTTAGATTATTTGTTTTTAAATTTAAAGGGAACTCAAATGACTAGGC
AAGGTTTTTGGAAAATAATAAAATTTTATGCAAAAGAAGCATCTATAGATAAAGAAATAGATTCTTATACACTAAGACAT
TCCTTTGCAGTACATTTACTTCAAAATGGAGCAGATATAAAATCTGTACAGGAACTTTTAGGTCATAAGGATCTAGCTGC
AACTCAAATTTATTCTAGTATATCAAAGAAGAGTAAAATAGCAGAAGTATATAAAAATGCTCATCCAAGGGCATAA

Upstream 100 bases:

>100_bases
TATATATAATTATATACTAGTTTTTAATAATTTTTTAAGAGGTTTTTAAATTAATTTGTTGAATATAATAAAGTAAGCTT
AAAAAATAGGGGAATGGTAA

Downstream 100 bases:

>100_bases
TTTTAATAAAGCTTTGAAGATAAAGGAGGAGTTAATTTTGAATTTAAAGAAAATAAAAGAAAGTGCAGATTTTGTGAAAA
ATAACATATCTATAATGCCT

Product: tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MKNIIENYIKDLQKKNLSKNTLEAYRRDVEKFSEFVRNREEKILSVDTVTIMAFVQYLQREGRATSSIVRNIVSIRNFYK
YLIKKNMVSEDPTLGYEIPKIERTIPKILSVEEVDKLLNSPDSSKKGLRDKAMLELMYATGVKITELLNLNIYDINLKFN
YIKCRGSKKRERIIPIGSYAIKCLKNYLEVRPAINVYNLDYLFLNLKGTQMTRQGFWKIIKFYAKEASIDKEIDSYTLRH
SFAVHLLQNGADIKSVQELLGHKDLAATQIYSSISKKSKIAEVYKNAHPRA

Sequences:

>Translated_291_residues
MKNIIENYIKDLQKKNLSKNTLEAYRRDVEKFSEFVRNREEKILSVDTVTIMAFVQYLQREGRATSSIVRNIVSIRNFYK
YLIKKNMVSEDPTLGYEIPKIERTIPKILSVEEVDKLLNSPDSSKKGLRDKAMLELMYATGVKITELLNLNIYDINLKFN
YIKCRGSKKRERIIPIGSYAIKCLKNYLEVRPAINVYNLDYLFLNLKGTQMTRQGFWKIIKFYAKEASIDKEIDSYTLRH
SFAVHLLQNGADIKSVQELLGHKDLAATQIYSSISKKSKIAEVYKNAHPRA
>Mature_291_residues
MKNIIENYIKDLQKKNLSKNTLEAYRRDVEKFSEFVRNREEKILSVDTVTIMAFVQYLQREGRATSSIVRNIVSIRNFYK
YLIKKNMVSEDPTLGYEIPKIERTIPKILSVEEVDKLLNSPDSSKKGLRDKAMLELMYATGVKITELLNLNIYDINLKFN
YIKCRGSKKRERIIPIGSYAIKCLKNYLEVRPAINVYNLDYLFLNLKGTQMTRQGFWKIIKFYAKEASIDKEIDSYTLRH
SFAVHLLQNGADIKSVQELLGHKDLAATQIYSSISKKSKIAEVYKNAHPRA

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=292, Percent_Identity=38.013698630137, Blast_Score=213, Evalue=2e-56,
Organism=Escherichia coli, GI1790244, Length=289, Percent_Identity=30.7958477508651, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1790767, Length=187, Percent_Identity=27.807486631016, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1790768, Length=181, Percent_Identity=24.8618784530387, Blast_Score=71, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 33822; Mature: 33822

Theoretical pI: Translated: 10.14; Mature: 10.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNIIENYIKDLQKKNLSKNTLEAYRRDVEKFSEFVRNREEKILSVDTVTIMAFVQYLQR
CHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EGRATSSIVRNIVSIRNFYKYLIKKNMVSEDPTLGYEIPKIERTIPKILSVEEVDKLLNS
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHCC
PDSSKKGLRDKAMLELMYATGVKITELLNLNIYDINLKFNYIKCRGSKKRERIIPIGSYA
CCCCCCCCHHHHHHHHHHHCCCHHHHHHCCEEEEEEEEEEEEEECCCCCCCCCCCCHHHH
IKCLKNYLEVRPAINVYNLDYLFLNLKGTQMTRQGFWKIIKFYAKEASIDKEIDSYTLRH
HHHHHHHHHHCCCCEEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFAVHLLQNGADIKSVQELLGHKDLAATQIYSSISKKSKIAEVYKNAHPRA
HHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKNIIENYIKDLQKKNLSKNTLEAYRRDVEKFSEFVRNREEKILSVDTVTIMAFVQYLQR
CHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EGRATSSIVRNIVSIRNFYKYLIKKNMVSEDPTLGYEIPKIERTIPKILSVEEVDKLLNS
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHCC
PDSSKKGLRDKAMLELMYATGVKITELLNLNIYDINLKFNYIKCRGSKKRERIIPIGSYA
CCCCCCCCHHHHHHHHHHHCCCHHHHHHCCEEEEEEEEEEEEEECCCCCCCCCCCCHHHH
IKCLKNYLEVRPAINVYNLDYLFLNLKGTQMTRQGFWKIIKFYAKEASIDKEIDSYTLRH
HHHHHHHHHHCCCCEEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFAVHLLQNGADIKSVQELLGHKDLAATQIYSSISKKSKIAEVYKNAHPRA
HHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]