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The map label for this gene is 226949094

Identifier: 226949094

GI number: 226949094

Start: 2078787

End: 2079974

Strand: Reverse

Name: 226949094

Synonym: CLM_2010

Alternate gene names: NA

Gene position: 2079974-2078787 (Counterclockwise)

Preceding gene: 226949095

Following gene: 226949093

Centisome position: 50.06

GC content: 29.38

Gene sequence:

>1188_bases
ATGGCATCAAGTTTAGCTATTATTATTCTATTGGGATTAATTGCAAATAAGCTCTTTGAAAAATTAAAACTGCCAGATCT
TTTAGGAATGTTAATATTAGGTATTTTAATAGGCCCTCATGGCTTAAACTGGTTAAGCAAAGATATTTTAAATGCTTCAT
CGGATCTTAGAAAAATTGCTTTAATTGTAATTTTATTAAGAGCAGGTTTAGGTCTTAATAAAGATGAATTAAAATTGGTT
GGTAAAACAGCTCTAAAATTAAGCTGTGTACCTGGAATTATAGAAGGATTTTTTATAGCAATAGCATCTATAAAACTTTT
AGGTTTTTCTTTTATACAAGGAGGCTTATTGGGATTTATTATTGCTGCAGTTTCCCCAGCAGTAGTTGTACCTCAGATGT
TGAGCTTAATGGACAAAGGCCTTGGTAAAGCTAAGGGTATACCAACTCTCATATTAGCCGGTGCTTCTATAGACGATGTT
TTTGCAATAACAATATTTAGTACATTTTTAGGATTATATTCAGGAAAAAATATAAATATAGGCATGCAAATCTTAAAGAT
ACCTATTTCCATAATATTAGGTACATTAATTGGTGTATTATCAGCAATCATTATTATAAAAATATTTAAAAAATATGCTA
TAGATAATACTAAGAAAATATTAATTATACTTAGCATATCTATTATACTTACCCTAATAGAAGCTTTACTAAAAGGTAAA
TTAGAAATAGCCAGTTTATTGGGTGTTATGGCCTTAGGATTTGTAATATCTGATAAAATTCCTAGTATAGGAGATAAAGT
ATCTAAAGGATTAAATGAAATATGGGTTTTTGCTCAAATACTTTTATTTGTTCTCGTAGGAGCTGAAGTAAATATGGTAA
TAGCTTTTAAATCAGGATTTTTAGGTATAATCATTATTGCTTTAGGTCTTATAGGAAGAAGTATAGGAGTATTAATTTCT
CTGAAAGGTTCAAATTTAAATAAAGAAGAAAAACTCTTTTGTATTATAGCCTATATCCCTAAAGCTACAGTTCAAGCAGC
TATGGGAGCAGTACCATTAGTCAATGGTGTAGAGGCAGGAGATATTATTTTAGCAATAGCAGTTTTGTCAATTTTAACTA
CAGCTCCATTGGGAGCTATAGCAATAAATTTATCTGGTCCAAAATTATTAGAATCAAACCTTTCTTAG

Upstream 100 bases:

>100_bases
GGAGTTCGCCATAATTGCGTAATGCTAATGACTCCTACAAATAATATAATTATTTGTAGGATTTTTTGCGTTTTGAGTAA
AATTTAAGGGAGGAAATTTT

Downstream 100 bases:

>100_bases
ACTAGATCAAATTTTTTATAAAATATATCTCTTTTGCTATAAAAAATTTTGAAAAATACAAGAAAATCATTAAGTTGTAT
AAAAATAGATTTAATTTTAA

Product: CPA2 family transporter

Products: NA

Alternate protein names: Na(+)/H(+) Antiporter; Transporter CPA2 Family; Na+/H+ Antiporter; Sodium/Proton Antiporter CPA1 Family; Na+/H+-Exchanging Protein; Sodium/Hydrogen Antiporter; Sodium/Hydrogen Exchanger Family Protein; Na+/H+-Exchanging ProteinNa+/H+ Antiporter; Monovalent CationProton Antiporter-2 Family Protein; Transporter Monovalent CationProton Antiporter-2 Family; Sodium/Hydrogen Exchanger/Universal Stress Family Protein

Number of amino acids: Translated: 395; Mature: 394

Protein sequence:

>395_residues
MASSLAIIILLGLIANKLFEKLKLPDLLGMLILGILIGPHGLNWLSKDILNASSDLRKIALIVILLRAGLGLNKDELKLV
GKTALKLSCVPGIIEGFFIAIASIKLLGFSFIQGGLLGFIIAAVSPAVVVPQMLSLMDKGLGKAKGIPTLILAGASIDDV
FAITIFSTFLGLYSGKNINIGMQILKIPISIILGTLIGVLSAIIIIKIFKKYAIDNTKKILIILSISIILTLIEALLKGK
LEIASLLGVMALGFVISDKIPSIGDKVSKGLNEIWVFAQILLFVLVGAEVNMVIAFKSGFLGIIIIALGLIGRSIGVLIS
LKGSNLNKEEKLFCIIAYIPKATVQAAMGAVPLVNGVEAGDIILAIAVLSILTTAPLGAIAINLSGPKLLESNLS

Sequences:

>Translated_395_residues
MASSLAIIILLGLIANKLFEKLKLPDLLGMLILGILIGPHGLNWLSKDILNASSDLRKIALIVILLRAGLGLNKDELKLV
GKTALKLSCVPGIIEGFFIAIASIKLLGFSFIQGGLLGFIIAAVSPAVVVPQMLSLMDKGLGKAKGIPTLILAGASIDDV
FAITIFSTFLGLYSGKNINIGMQILKIPISIILGTLIGVLSAIIIIKIFKKYAIDNTKKILIILSISIILTLIEALLKGK
LEIASLLGVMALGFVISDKIPSIGDKVSKGLNEIWVFAQILLFVLVGAEVNMVIAFKSGFLGIIIIALGLIGRSIGVLIS
LKGSNLNKEEKLFCIIAYIPKATVQAAMGAVPLVNGVEAGDIILAIAVLSILTTAPLGAIAINLSGPKLLESNLS
>Mature_394_residues
ASSLAIIILLGLIANKLFEKLKLPDLLGMLILGILIGPHGLNWLSKDILNASSDLRKIALIVILLRAGLGLNKDELKLVG
KTALKLSCVPGIIEGFFIAIASIKLLGFSFIQGGLLGFIIAAVSPAVVVPQMLSLMDKGLGKAKGIPTLILAGASIDDVF
AITIFSTFLGLYSGKNINIGMQILKIPISIILGTLIGVLSAIIIIKIFKKYAIDNTKKILIILSISIILTLIEALLKGKL
EIASLLGVMALGFVISDKIPSIGDKVSKGLNEIWVFAQILLFVLVGAEVNMVIAFKSGFLGIIIIALGLIGRSIGVLISL
KGSNLNKEEKLFCIIAYIPKATVQAAMGAVPLVNGVEAGDIILAIAVLSILTTAPLGAIAINLSGPKLLESNLS

Specific function: Unknown

COG id: COG0025

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI47271479, Length=356, Percent_Identity=35.6741573033708, Blast_Score=162, Evalue=6e-40,
Organism=Homo sapiens, GI66793392, Length=357, Percent_Identity=34.453781512605, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI154937338, Length=302, Percent_Identity=34.7682119205298, Blast_Score=136, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI17567635, Length=405, Percent_Identity=28.8888888888889, Blast_Score=115, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI25152227, Length=422, Percent_Identity=26.5402843601896, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI32566724, Length=174, Percent_Identity=35.0574712643678, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI45550940, Length=384, Percent_Identity=36.1979166666667, Blast_Score=156, Evalue=2e-38,
Organism=Drosophila melanogaster, GI20129297, Length=384, Percent_Identity=36.1979166666667, Blast_Score=156, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24649169, Length=398, Percent_Identity=32.6633165829146, Blast_Score=122, Evalue=5e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 41434; Mature: 41302

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASSLAIIILLGLIANKLFEKLKLPDLLGMLILGILIGPHGLNWLSKDILNASSDLRKIA
CCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHH
LIVILLRAGLGLNKDELKLVGKTALKLSCVPGIIEGFFIAIASIKLLGFSFIQGGLLGFI
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAAVSPAVVVPQMLSLMDKGLGKAKGIPTLILAGASIDDVFAITIFSTFLGLYSGKNINI
HHHHCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCC
GMQILKIPISIILGTLIGVLSAIIIIKIFKKYAIDNTKKILIILSISIILTLIEALLKGK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHCC
LEIASLLGVMALGFVISDKIPSIGDKVSKGLNEIWVFAQILLFVLVGAEVNMVIAFKSGF
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCH
LGIIIIALGLIGRSIGVLISLKGSNLNKEEKLFCIIAYIPKATVQAAMGAVPLVNGVEAG
HHHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEEEEEECCHHHHHHHHCCCCCCCCCCHH
DIILAIAVLSILTTAPLGAIAINLSGPKLLESNLS
HHHHHHHHHHHHHHCCCCEEEEECCCCHHHHCCCC
>Mature Secondary Structure 
ASSLAIIILLGLIANKLFEKLKLPDLLGMLILGILIGPHGLNWLSKDILNASSDLRKIA
CCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHH
LIVILLRAGLGLNKDELKLVGKTALKLSCVPGIIEGFFIAIASIKLLGFSFIQGGLLGFI
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAAVSPAVVVPQMLSLMDKGLGKAKGIPTLILAGASIDDVFAITIFSTFLGLYSGKNINI
HHHHCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCC
GMQILKIPISIILGTLIGVLSAIIIIKIFKKYAIDNTKKILIILSISIILTLIEALLKGK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHCC
LEIASLLGVMALGFVISDKIPSIGDKVSKGLNEIWVFAQILLFVLVGAEVNMVIAFKSGF
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCH
LGIIIIALGLIGRSIGVLISLKGSNLNKEEKLFCIIAYIPKATVQAAMGAVPLVNGVEAG
HHHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEEEEEECCHHHHHHHHCCCCCCCCCCHH
DIILAIAVLSILTTAPLGAIAINLSGPKLLESNLS
HHHHHHHHHHHHHHCCCCEEEEECCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA