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The map label for this gene is hypE [H]

Identifier: 226949074

GI number: 226949074

Start: 2054309

End: 2055313

Strand: Reverse

Name: hypE [H]

Synonym: CLM_1990

Alternate gene names: 226949074

Gene position: 2055313-2054309 (Counterclockwise)

Preceding gene: 226949075

Following gene: 226949069

Centisome position: 49.46

GC content: 28.36

Gene sequence:

>1005_bases
ATGAATGGATTTATTACATTAAGTCATGGGCATGGAGGCAAATATACTCATGAACTTATAGAAAAGCTTATGTATAAATA
TTTTAATAATAAAACCCTCATAGAAGGTATAGATTCTGCAACTTTTAATATAAAAAAAGGAAAGTTAGCCTTTACTACAG
ATTCCTTTGTAGTAAAACCCTTATTTTTCAATGGGGGAGATATAGGAAAGTTGGCTATATGCGGTACTGTGAATGATTTA
TCTGTATCTGGAGCTAACCCTCTTTATTTAAGCTGTTCCTTTATAATAGAAGAGGGATTTCCTATAGAAAAATTAGAGAT
TATAATAAAATCTATGGCAGATACTGCTAAAGAAGCTAATGTCTTAATAGTAACGGGAGATACTAAAGTGGTAGAAAAAG
GATCTGTAGATCAAATTTTTATAAATACTTCAGGCATAGGAATTATAGAAGAGCAATATTCTATTAAAAATATTGAAGAA
GGTGACAAAGTTATAGTTACAGGAAACATAGGGGATCATGGAACAACTATAGCTTTAGATAGGTATAATTTAAACATAAA
AGGAAATTTAAAAAGCGATTGTACACCAGTAAATGCTATAACTAACAAATTAAAAGAATATTATCCTTATATAAAAATAA
TGAAAGATCCTACTAGAGGAGGAGTTGCTACAACTTTAAATGAAATATCATCACTAAGTAAAAATTTAGGTATATGTGTT
TGGGAAGATAAAATACCTATAAAAAATGAAGTTAAAGCAATAAATGAAATGTTAGGTCTAGATCCTTTATACATGGCCTG
TGAAGGAAGAATAGTTATGGTGGTAAAAGATCAATATGCAAAGGATATACTAAAAATCATAAAAGAAATAGATAATTGTA
AAAATGCAGAAATAATAGGTACTTTTGTGAAAAATTCATACAATATAGTATATGTAGAAAATTTTTTAGGTGGCACACGA
ATAATAAATATGTTAGAAGGGGATATGCTTCCAAGAATATGTTAA

Upstream 100 bases:

>100_bases
AAATAACTGGCTTTTAAACAAAAAGGTAAAATCGTAAATTGATGATTTAGTTTAAATACTTTCCAAAGAATAATTCTAAG
ATACAAGGAGGAAATATGGA

Downstream 100 bases:

>100_bases
ATATATTTTAGTTAATTAAAAGACTTTTATATAAGAATGTTTATATAAATCACATAAAATTCAAATTAAAAAGTTTATTT
TAAGTTATGATGATTAAGTT

Product: hydrogenase expression/formation protein HypE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MNGFITLSHGHGGKYTHELIEKLMYKYFNNKTLIEGIDSATFNIKKGKLAFTTDSFVVKPLFFNGGDIGKLAICGTVNDL
SVSGANPLYLSCSFIIEEGFPIEKLEIIIKSMADTAKEANVLIVTGDTKVVEKGSVDQIFINTSGIGIIEEQYSIKNIEE
GDKVIVTGNIGDHGTTIALDRYNLNIKGNLKSDCTPVNAITNKLKEYYPYIKIMKDPTRGGVATTLNEISSLSKNLGICV
WEDKIPIKNEVKAINEMLGLDPLYMACEGRIVMVVKDQYAKDILKIIKEIDNCKNAEIIGTFVKNSYNIVYVENFLGGTR
IINMLEGDMLPRIC

Sequences:

>Translated_334_residues
MNGFITLSHGHGGKYTHELIEKLMYKYFNNKTLIEGIDSATFNIKKGKLAFTTDSFVVKPLFFNGGDIGKLAICGTVNDL
SVSGANPLYLSCSFIIEEGFPIEKLEIIIKSMADTAKEANVLIVTGDTKVVEKGSVDQIFINTSGIGIIEEQYSIKNIEE
GDKVIVTGNIGDHGTTIALDRYNLNIKGNLKSDCTPVNAITNKLKEYYPYIKIMKDPTRGGVATTLNEISSLSKNLGICV
WEDKIPIKNEVKAINEMLGLDPLYMACEGRIVMVVKDQYAKDILKIIKEIDNCKNAEIIGTFVKNSYNIVYVENFLGGTR
IINMLEGDMLPRIC
>Mature_334_residues
MNGFITLSHGHGGKYTHELIEKLMYKYFNNKTLIEGIDSATFNIKKGKLAFTTDSFVVKPLFFNGGDIGKLAICGTVNDL
SVSGANPLYLSCSFIIEEGFPIEKLEIIIKSMADTAKEANVLIVTGDTKVVEKGSVDQIFINTSGIGIIEEQYSIKNIEE
GDKVIVTGNIGDHGTTIALDRYNLNIKGNLKSDCTPVNAITNKLKEYYPYIKIMKDPTRGGVATTLNEISSLSKNLGICV
WEDKIPIKNEVKAINEMLGLDPLYMACEGRIVMVVKDQYAKDILKIIKEIDNCKNAEIIGTFVKNSYNIVYVENFLGGTR
IINMLEGDMLPRIC

Specific function: Unknown

COG id: COG0309

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypE family [H]

Homologues:

Organism=Escherichia coli, GI226510967, Length=337, Percent_Identity=41.5430267062315, Blast_Score=270, Evalue=1e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR011854
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: NA

Molecular weight: Translated: 36918; Mature: 36918

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGFITLSHGHGGKYTHELIEKLMYKYFNNKTLIEGIDSATFNIKKGKLAFTTDSFVVKP
CCCEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCEEEEECCEEEEEECCEEEEE
LFFNGGDIGKLAICGTVNDLSVSGANPLYLSCSFIIEEGFPIEKLEIIIKSMADTAKEAN
EEECCCCCCEEEEEECCCCCEECCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHCC
VLIVTGDTKVVEKGSVDQIFINTSGIGIIEEQYSIKNIEEGDKVIVTGNIGDHGTTIALD
EEEEECCCEEEECCCCCEEEEECCCCEEEECCCCCCCCCCCCEEEEECCCCCCCCEEEEE
RYNLNIKGNLKSDCTPVNAITNKLKEYYPYIKIMKDPTRGGVATTLNEISSLSKNLGICV
EEEEEEECCCCCCCCCHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHCCEEE
WEDKIPIKNEVKAINEMLGLDPLYMACEGRIVMVVKDQYAKDILKIIKEIDNCKNAEIIG
EECCCCCHHHHHHHHHHHCCCCEEEECCCEEEEEECCHHHHHHHHHHHHHHCCCCCEEEE
TFVKNSYNIVYVENFLGGTRIINMLEGDMLPRIC
EECCCCEEEEEEECCCCHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNGFITLSHGHGGKYTHELIEKLMYKYFNNKTLIEGIDSATFNIKKGKLAFTTDSFVVKP
CCCEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCEEEEECCEEEEEECCEEEEE
LFFNGGDIGKLAICGTVNDLSVSGANPLYLSCSFIIEEGFPIEKLEIIIKSMADTAKEAN
EEECCCCCCEEEEEECCCCCEECCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHCC
VLIVTGDTKVVEKGSVDQIFINTSGIGIIEEQYSIKNIEEGDKVIVTGNIGDHGTTIALD
EEEEECCCEEEECCCCCEEEEECCCCEEEECCCCCCCCCCCCEEEEECCCCCCCCEEEEE
RYNLNIKGNLKSDCTPVNAITNKLKEYYPYIKIMKDPTRGGVATTLNEISSLSKNLGICV
EEEEEEECCCCCCCCCHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHCCEEE
WEDKIPIKNEVKAINEMLGLDPLYMACEGRIVMVVKDQYAKDILKIIKEIDNCKNAEIIG
EECCCCCHHHHHHHHHHHCCCCEEEECCCEEEEEECCHHHHHHHHHHHHHHCCCCCEEEE
TFVKNSYNIVYVENFLGGTRIINMLEGDMLPRIC
EECCCCEEEEEEECCCCHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8510650; 7906310; 12597275 [H]