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The map label for this gene is hypD [H]

Identifier: 226949075

GI number: 226949075

Start: 2055481

End: 2056554

Strand: Reverse

Name: hypD [H]

Synonym: CLM_1991

Alternate gene names: 226949075

Gene position: 2056554-2055481 (Counterclockwise)

Preceding gene: 226949076

Following gene: 226949074

Centisome position: 49.49

GC content: 28.21

Gene sequence:

>1074_bases
ATGGATAATTGTAAATTAATAGTTGAAATCATGGAGAAGATAAAAGCTATAGATACAAGTCCTTTGAAGATAATGGAAGT
ATGCGGTAGTCATACGGAAGTTATAGATAGATTAGGCTTGAGAGATATTTTATATCCTAAAGTAAATTTAGTATCTGGCC
CCGGTTGCCCTGTATGCGTAACAGATGAAAGCTATATAGATGTAGTCCTAAAGCTTTTAAATAGTAAAAATGTATTAATA
ACTACTTTTGGTGATTTAATGAAAGTGAAAGGTACTACTAATAGTTTAATGGATGAAAAACCAAATCACAATAATATAAA
AGTTATATACTCGCCATTAGAGGCGCTTAAGATAGCAAAAGAAAATAAATCTTTAGAGGTTATTTTTCTAGCAGTTGGTT
TTGAAACTACTGCCCCTTTAATAGCCTTATCTATAAAGCAAGCTAAAAATGAAAAGATAAAAAATATAAGTTTTCTACTA
GGTTTAAAAACAATGAAACCCATATTAGAACATATATTAAAAGATAAAAATCATAATATAGATGGGTTAATTTGTCCAGG
CCATGTAGCTTCTGTTAAGGGCGCTAATTATTTTAGATTTATAAGGGATGCATATAATATTCCTGCAGTAATATCAGGAT
TTCAACCCTTAGATATCTTAAGCTCTATATATTTTATTATAAATGGTAATATAAAGAATAAAAAAACTTTTATAAATTTA
TATAAAACCTGTGTAAAAGAAAATGGAAATAAAATTGCTAATGAGCTTATAGATGAGGTTTTTTGCCAAAATGATTCAAA
TTGGAGAGGTATAGGATTGATTAAAAACTCTGGATTAGATCTAAAAAATATATATAGTGACTATAATGCTTTTAAAAAAT
TCAATGTAAAAATTGAAAAGCATGAAAAATCCACTAGATGTATATGCGGTGAAGTTATATTAGGTAAAAAGTCTCCTAAA
GAATGTGACCTGTTTTCTAAAGAATGTAATCCAAGCCATTCAAAGGGCCCTTGTATGGTATCTAAAGAAGGGGCTTGTTC
TATATTTTATAGATACAATAAATTTAAGCTCTAA

Upstream 100 bases:

>100_bases
TATGTTCTAATTCATGCAGGTTGTGCTATAGAAAAAATAGACTATGAGTATTTTTCTTACTTAGAACAAACTATAAAAGA
AGCCTTAAGGAGTAATACAG

Downstream 100 bases:

>100_bases
AGAATATTAAATTATAAACTAAAAGTGTAAAATACAAGACTTAAGCGGAAAGTACAAATTATTAATTAAATAACTGGCTT
TTAAACAAAAAGGTAAAATC

Product: hydrogenase expression/formation protein HypD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MDNCKLIVEIMEKIKAIDTSPLKIMEVCGSHTEVIDRLGLRDILYPKVNLVSGPGCPVCVTDESYIDVVLKLLNSKNVLI
TTFGDLMKVKGTTNSLMDEKPNHNNIKVIYSPLEALKIAKENKSLEVIFLAVGFETTAPLIALSIKQAKNEKIKNISFLL
GLKTMKPILEHILKDKNHNIDGLICPGHVASVKGANYFRFIRDAYNIPAVISGFQPLDILSSIYFIINGNIKNKKTFINL
YKTCVKENGNKIANELIDEVFCQNDSNWRGIGLIKNSGLDLKNIYSDYNAFKKFNVKIEKHEKSTRCICGEVILGKKSPK
ECDLFSKECNPSHSKGPCMVSKEGACSIFYRYNKFKL

Sequences:

>Translated_357_residues
MDNCKLIVEIMEKIKAIDTSPLKIMEVCGSHTEVIDRLGLRDILYPKVNLVSGPGCPVCVTDESYIDVVLKLLNSKNVLI
TTFGDLMKVKGTTNSLMDEKPNHNNIKVIYSPLEALKIAKENKSLEVIFLAVGFETTAPLIALSIKQAKNEKIKNISFLL
GLKTMKPILEHILKDKNHNIDGLICPGHVASVKGANYFRFIRDAYNIPAVISGFQPLDILSSIYFIINGNIKNKKTFINL
YKTCVKENGNKIANELIDEVFCQNDSNWRGIGLIKNSGLDLKNIYSDYNAFKKFNVKIEKHEKSTRCICGEVILGKKSPK
ECDLFSKECNPSHSKGPCMVSKEGACSIFYRYNKFKL
>Mature_357_residues
MDNCKLIVEIMEKIKAIDTSPLKIMEVCGSHTEVIDRLGLRDILYPKVNLVSGPGCPVCVTDESYIDVVLKLLNSKNVLI
TTFGDLMKVKGTTNSLMDEKPNHNNIKVIYSPLEALKIAKENKSLEVIFLAVGFETTAPLIALSIKQAKNEKIKNISFLL
GLKTMKPILEHILKDKNHNIDGLICPGHVASVKGANYFRFIRDAYNIPAVISGFQPLDILSSIYFIINGNIKNKKTFINL
YKTCVKENGNKIANELIDEVFCQNDSNWRGIGLIKNSGLDLKNIYSDYNAFKKFNVKIEKHEKSTRCICGEVILGKKSPK
ECDLFSKECNPSHSKGPCMVSKEGACSIFYRYNKFKL

Specific function: Required for the formation of all three hydrogenase isoenzymes [H]

COG id: COG0409

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypD family [H]

Homologues:

Organism=Escherichia coli, GI1789084, Length=354, Percent_Identity=37.5706214689266, Blast_Score=285, Evalue=3e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002780 [H]

Pfam domain/function: PF01924 HypD [H]

EC number: NA

Molecular weight: Translated: 40033; Mature: 40033

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNCKLIVEIMEKIKAIDTSPLKIMEVCGSHTEVIDRLGLRDILYPKVNLVSGPGCPVCV
CCCHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHCCCHHHCCCCEEEECCCCCCEEE
TDESYIDVVLKLLNSKNVLITTFGDLMKVKGTTNSLMDEKPNHNNIKVIYSPLEALKIAK
CCHHHHHHHHHHHCCCCEEEEECCCCEEECCCCHHHHCCCCCCCCEEEEECCHHHHHHHH
ENKSLEVIFLAVGFETTAPLIALSIKQAKNEKIKNISFLLGLKTMKPILEHILKDKNHNI
CCCCEEEEEEEECCCCCCCHHEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DGLICPGHVASVKGANYFRFIRDAYNIPAVISGFQPLDILSSIYFIINGNIKNKKTFINL
CEEECCCCHHHCCCCHHHHHHHHHCCCCHHHCCCCHHHHHHHEEEEEECCCCCHHHHHHH
YKTCVKENGNKIANELIDEVFCQNDSNWRGIGLIKNSGLDLKNIYSDYNAFKKFNVKIEK
HHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHEEEEEEE
HEKSTRCICGEVILGKKSPKECDLFSKECNPSHSKGPCMVSKEGACSIFYRYNKFKL
CCCCCCEEECHHEECCCCCCCCCCHHCCCCCCCCCCCEEEECCCCEEEEEEECEECC
>Mature Secondary Structure
MDNCKLIVEIMEKIKAIDTSPLKIMEVCGSHTEVIDRLGLRDILYPKVNLVSGPGCPVCV
CCCHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHCCCHHHCCCCEEEECCCCCCEEE
TDESYIDVVLKLLNSKNVLITTFGDLMKVKGTTNSLMDEKPNHNNIKVIYSPLEALKIAK
CCHHHHHHHHHHHCCCCEEEEECCCCEEECCCCHHHHCCCCCCCCEEEEECCHHHHHHHH
ENKSLEVIFLAVGFETTAPLIALSIKQAKNEKIKNISFLLGLKTMKPILEHILKDKNHNI
CCCCEEEEEEEECCCCCCCHHEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DGLICPGHVASVKGANYFRFIRDAYNIPAVISGFQPLDILSSIYFIINGNIKNKKTFINL
CEEECCCCHHHCCCCHHHHHHHHHCCCCHHHCCCCHHHHHHHEEEEEECCCCCHHHHHHH
YKTCVKENGNKIANELIDEVFCQNDSNWRGIGLIKNSGLDLKNIYSDYNAFKKFNVKIEK
HHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHEEEEEEE
HEKSTRCICGEVILGKKSPKECDLFSKECNPSHSKGPCMVSKEGACSIFYRYNKFKL
CCCCCCEEECHHEECCCCCCCCCCHHCCCCCCCCCCCEEEECCCCEEEEEEECEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1849603; 9278503 [H]