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The map label for this gene is opuBB [H]

Identifier: 226948964

GI number: 226948964

Start: 1919746

End: 1921329

Strand: Direct

Name: opuBB [H]

Synonym: CLM_1878

Alternate gene names: 226948964

Gene position: 1919746-1921329 (Clockwise)

Preceding gene: 226948963

Following gene: 226948965

Centisome position: 46.2

GC content: 29.67

Gene sequence:

>1584_bases
ATGAATAGTTTTATAGAACAATTAATACTGAAAAAATCACAAATATTGTCTCTTCTAGTAGAACATGTAGAACTTACTTT
AATATCAGTTTTAGTAGCAGTAGCTATTGGAGTACCTCTTGGTATAATTATTACTAAAAATAAAAAGTTAGCTAAAACAG
TAATAGGTTTTGCAAATTTAACTCAAGCTATACCAAGTTTAGCTATTTTAGGGTTTTTAATACCTTTAATAGGCATAGGA
TCAGCACCTGCTATAACTATGGTTGTTTTATATTCAATGTTACCAATATTAAAAAATACTTATACAGGAATTACAAATAT
AAATCCAGATATGTTAGAAGCAGCTAAAGGTTTAGGTATGACAAACACCCAAACTCTTAAATTAATAAAAATACCTTTAG
CAATGCCAATAATAATGGCAGGTATAAGAATAGCATCAGTAACAGCTGTTGGGCTTATGACTATAGCAGCTTTTATTGGT
GCAGGTGGACTTGGATACTTAGTATTCTCAGGAATACAAACTGTAGATAATAATCTTATACTATTTGGTGCTATTCCAGC
GGCTATATTAGCTTTAGTAATAGATTGGGTAACAGGTAAAATAGAAGATGCTACTATGCCAAATGGTATAAAAAAAGCAG
ATGGCACAATGAAAATAAAAAGAAGCTCTTCAAATAAAAACAGGAAAAGGAATACTATAATAGCATCAATAGTTGGAGTT
TGTATATTGTTAGCATTAGTAGCTCCAAAGATATTAGGAATGGGACACAAAAAAGTAGTTATTGGTTCTAAAAATTTTAC
GGAACAACTGATTTTAGGTAATATATTAGAAGAACTAATTAAAGACAAAACGGATATGGATGTTGAAACAAAGTTAAATT
TAGGAGGAACTCAAGTAAGTTTTAATGCACTAAAATCTGGTGGAATAGATATGTATATTGAGTATACAGGTACTGCATAT
GGAAATATACTAAATATAAAAGAACCTAATAGAGATAAAGATGCTGTTTATAATAGAGTTAAAAAGGACTTTAAAGAAAA
ATTTGGAATTGAAATATTAAATCCTATGGGCTTTAACAATACTTATGCAATGGCAACTACAAAAGAGATTGCACAAAAGT
ATAATTTAAAAACAACATCAGATCTAGCAAAGGAATCAAGCAATATGATAGCAGGACCAACAATAGAATTTGCAAATAGA
GAAGATGGGCTTATAGGACTTAATAAAGCATATAATGTGAATTTTAAAGGCGTTAATCCAATAGACGGTGGGCTAAGATA
TACAGCCTTAGTTAATAATGAAACTCAAATTATAGATGCTTTTACAACAGATGGGTTAATAGAACAGTTTAATTTAGTTC
TTTTAGAGGATGACAAGAGCTTTTTTCCAGACTATTATGCAGTTCCAATCGTAAAAGAAGAAACATTAAAAAAATTCCCA
GAGCTTAGGGAAGTTTTAGGAAATCTAGATGGAAGAATAACTGACGAAAAAATGAGAAAATTAAACTATGAAGTAGATGT
AAACAAAAGAGACCCTAAACAAGTAGCAAAAGAATTTTTGCAAAAAGAAGGGTTAATAGATTAA

Upstream 100 bases:

>100_bases
CCTGTAAGGGATAGTGAAGGAAAACTTTTAGGATTGATAACAAGAAGTAGTTTAATATCAGTTTTAAGTAGTCAGTATAT
AGATATGGAGGGGATAATTG

Downstream 100 bases:

>100_bases
AATATTTAAATATATTTAATTTATAAGAAGAAATTTTAAATAAATAAAATAGAAATATACCTGGAAGAGAAAAACAGAGA
ATTTCTATATAAAGCAATAG

Product: glycine betaine/L-proline ABC transporter permease/glycine betaine/L-proline-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 527; Mature: 527

Protein sequence:

>527_residues
MNSFIEQLILKKSQILSLLVEHVELTLISVLVAVAIGVPLGIIITKNKKLAKTVIGFANLTQAIPSLAILGFLIPLIGIG
SAPAITMVVLYSMLPILKNTYTGITNINPDMLEAAKGLGMTNTQTLKLIKIPLAMPIIMAGIRIASVTAVGLMTIAAFIG
AGGLGYLVFSGIQTVDNNLILFGAIPAAILALVIDWVTGKIEDATMPNGIKKADGTMKIKRSSSNKNRKRNTIIASIVGV
CILLALVAPKILGMGHKKVVIGSKNFTEQLILGNILEELIKDKTDMDVETKLNLGGTQVSFNALKSGGIDMYIEYTGTAY
GNILNIKEPNRDKDAVYNRVKKDFKEKFGIEILNPMGFNNTYAMATTKEIAQKYNLKTTSDLAKESSNMIAGPTIEFANR
EDGLIGLNKAYNVNFKGVNPIDGGLRYTALVNNETQIIDAFTTDGLIEQFNLVLLEDDKSFFPDYYAVPIVKEETLKKFP
ELREVLGNLDGRITDEKMRKLNYEVDVNKRDPKQVAKEFLQKEGLID

Sequences:

>Translated_527_residues
MNSFIEQLILKKSQILSLLVEHVELTLISVLVAVAIGVPLGIIITKNKKLAKTVIGFANLTQAIPSLAILGFLIPLIGIG
SAPAITMVVLYSMLPILKNTYTGITNINPDMLEAAKGLGMTNTQTLKLIKIPLAMPIIMAGIRIASVTAVGLMTIAAFIG
AGGLGYLVFSGIQTVDNNLILFGAIPAAILALVIDWVTGKIEDATMPNGIKKADGTMKIKRSSSNKNRKRNTIIASIVGV
CILLALVAPKILGMGHKKVVIGSKNFTEQLILGNILEELIKDKTDMDVETKLNLGGTQVSFNALKSGGIDMYIEYTGTAY
GNILNIKEPNRDKDAVYNRVKKDFKEKFGIEILNPMGFNNTYAMATTKEIAQKYNLKTTSDLAKESSNMIAGPTIEFANR
EDGLIGLNKAYNVNFKGVNPIDGGLRYTALVNNETQIIDAFTTDGLIEQFNLVLLEDDKSFFPDYYAVPIVKEETLKKFP
ELREVLGNLDGRITDEKMRKLNYEVDVNKRDPKQVAKEFLQKEGLID
>Mature_527_residues
MNSFIEQLILKKSQILSLLVEHVELTLISVLVAVAIGVPLGIIITKNKKLAKTVIGFANLTQAIPSLAILGFLIPLIGIG
SAPAITMVVLYSMLPILKNTYTGITNINPDMLEAAKGLGMTNTQTLKLIKIPLAMPIIMAGIRIASVTAVGLMTIAAFIG
AGGLGYLVFSGIQTVDNNLILFGAIPAAILALVIDWVTGKIEDATMPNGIKKADGTMKIKRSSSNKNRKRNTIIASIVGV
CILLALVAPKILGMGHKKVVIGSKNFTEQLILGNILEELIKDKTDMDVETKLNLGGTQVSFNALKSGGIDMYIEYTGTAY
GNILNIKEPNRDKDAVYNRVKKDFKEKFGIEILNPMGFNNTYAMATTKEIAQKYNLKTTSDLAKESSNMIAGPTIEFANR
EDGLIGLNKAYNVNFKGVNPIDGGLRYTALVNNETQIIDAFTTDGLIEQFNLVLLEDDKSFFPDYYAVPIVKEETLKKFP
ELREVLGNLDGRITDEKMRKLNYEVDVNKRDPKQVAKEFLQKEGLID

Specific function: Involved in a high affinity multicomponent binding- protein-dependent transport system for choline; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1732

COG function: function code M; Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788451, Length=193, Percent_Identity=36.2694300518135, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1788449, Length=192, Percent_Identity=33.3333333333333, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1788452, Length=302, Percent_Identity=27.4834437086093, Blast_Score=105, Evalue=9e-24,
Organism=Escherichia coli, GI1789033, Length=163, Percent_Identity=33.1288343558282, Blast_Score=102, Evalue=8e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 57517; Mature: 57517

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSFIEQLILKKSQILSLLVEHVELTLISVLVAVAIGVPLGIIITKNKKLAKTVIGFANL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHH
TQAIPSLAILGFLIPLIGIGSAPAITMVVLYSMLPILKNTYTGITNINPDMLEAAKGLGM
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCC
TNTQTLKLIKIPLAMPIIMAGIRIASVTAVGLMTIAAFIGAGGLGYLVFSGIQTVDNNLI
CCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEE
LFGAIPAAILALVIDWVTGKIEDATMPNGIKKADGTMKIKRSSSNKNRKRNTIIASIVGV
EEECHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHH
CILLALVAPKILGMGHKKVVIGSKNFTEQLILGNILEELIKDKTDMDVETKLNLGGTQVS
HHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCEEE
FNALKSGGIDMYIEYTGTAYGNILNIKEPNRDKDAVYNRVKKDFKEKFGIEILNPMGFNN
HHHHHCCCEEEEEEEECCCCCCEEECCCCCCCHHHHHHHHHHHHHHHCCCEEECCCCCCC
TYAMATTKEIAQKYNLKTTSDLAKESSNMIAGPTIEFANREDGLIGLNKAYNVNFKGVNP
EEEEHHHHHHHHHCCCCCHHHHHHHCCCEECCCEEEECCCCCCEEECCCEEEEECCCCCC
IDGGLRYTALVNNETQIIDAFTTDGLIEQFNLVLLEDDKSFFPDYYAVPIVKEETLKKFP
CCCCEEEEEEECCCCEEEEEHHCCCHHHHCCEEEEECCCCCCCCCEEECEECHHHHHHHH
ELREVLGNLDGRITDEKMRKLNYEVDVNKRDPKQVAKEFLQKEGLID
HHHHHHHCCCCCCCHHHHHHCCCEEECCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNSFIEQLILKKSQILSLLVEHVELTLISVLVAVAIGVPLGIIITKNKKLAKTVIGFANL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHH
TQAIPSLAILGFLIPLIGIGSAPAITMVVLYSMLPILKNTYTGITNINPDMLEAAKGLGM
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCC
TNTQTLKLIKIPLAMPIIMAGIRIASVTAVGLMTIAAFIGAGGLGYLVFSGIQTVDNNLI
CCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEE
LFGAIPAAILALVIDWVTGKIEDATMPNGIKKADGTMKIKRSSSNKNRKRNTIIASIVGV
EEECHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHH
CILLALVAPKILGMGHKKVVIGSKNFTEQLILGNILEELIKDKTDMDVETKLNLGGTQVS
HHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCEEE
FNALKSGGIDMYIEYTGTAYGNILNIKEPNRDKDAVYNRVKKDFKEKFGIEILNPMGFNN
HHHHHCCCEEEEEEEECCCCCCEEECCCCCCCHHHHHHHHHHHHHHHCCCEEECCCCCCC
TYAMATTKEIAQKYNLKTTSDLAKESSNMIAGPTIEFANREDGLIGLNKAYNVNFKGVNP
EEEEHHHHHHHHHCCCCCHHHHHHHCCCEECCCEEEECCCCCCEEECCCEEEEECCCCCC
IDGGLRYTALVNNETQIIDAFTTDGLIEQFNLVLLEDDKSFFPDYYAVPIVKEETLKKFP
CCCCEEEEEEECCCCEEEEEHHCCCHHHHCCEEEEECCCCCCCCCEEECEECHHHHHHHH
ELREVLGNLDGRITDEKMRKLNYEVDVNKRDPKQVAKEFLQKEGLID
HHHHHHHCCCCCCCHHHHHHCCCEEECCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592481; 10216873; 9384377 [H]