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The map label for this gene is nprM [H]

Identifier: 226948709

GI number: 226948709

Start: 1679297

End: 1681036

Strand: Reverse

Name: nprM [H]

Synonym: CLM_1609

Alternate gene names: 226948709

Gene position: 1681036-1679297 (Counterclockwise)

Preceding gene: 226948710

Following gene: 226948708

Centisome position: 40.46

GC content: 30.17

Gene sequence:

>1740_bases
ATGAAAAGTAAAAAATTATTAGCTACAGTGTTAAGTGCTGTAATAACTTTTTCTACTGTTTCAGCAGTTTATGCTGCACC
TGTAGGAAAAGAGAATAAAAGTGAGCCAAAAACCACAACAATATTTTGGGAAAACAACACACAAAATACCAGAAAAGCTA
CTACTGGCATAACTCAAGAGAAATTTAACAATTCTCAGGATATAACTAATTTCTTTGAAAAGAACATCTCTAAATTTGGT
GTAAAGAAAGGTTCTCTTAAAAATACTAAAGTTGTAAAAGATGACAAAGGTAAAACTAACTATCATATGATCTATCAAGT
AGATGATATCCCTGTATATTATGGTAGAATTGTTTTTACAACTAAAAAAGACTCATCTATAGACTCTATAACTGGTAGAA
TTGATGCTACTTTTGAAAATGACAGTTGGAAAGACAAAGTAAAACTATCAAAGGATAATGCTATAGAAAAAGCTAAAGAT
AGCATAAAATGCGATAGCTTATCTAAAACCAATGCAGATTTATATTTATACAATTTTGAAGGAAAACCTTATGTAGCTTA
TTTAGTTAATTTGGTTGCAGATAATGGAGATTGGAATGTTTTTGTTAATGCTGAAGATGGTTCTATAGTAAATCAATTTA
ACAACACCCCTACCCTAATTGATAATAAAGATGAAGATTTACCTAATGCTGAAGAAATTAAAAAAGCTTCCAAAGAACCT
GCCAATATAAATAGTGTAATAAATGTTAATGGTGAAACTGTTAAAGGACAAGGTAAAACTACTTTAGACGGAATAGTTGA
TATTGATTTAACTTATAAAGATGGAAAATATTATTTGAAAGATAGTAATAAAAATGTTTATCTATATGACGTAAATCATA
GTCTTACTCCTATGTATTCTCGCTTTAAAGATCGTATATTAAGACACTCAACTCTTGTAGAAAATAACAGCAATAAATTT
ACAAGTGATGAACATGTTACTGCAGTAGATGGTTACGTTAATTTATCAAAAACTTATGATTACTATAAAAATAAGTTTAA
TAGAAATAGTATAGATAATAACGGTATGAATGTTGAAGGATTTATCCATACTGGTGTAAAATACAATAATGCCTTTTGGA
GAGATGATCTTGGTTCTATGTTCTTCGGTGATGGAGATGGAGTAAAATTCTCTTCCTTTGCAAGTGCTTTAGATGTTGTA
GGTCATGAAGTGAGCCATGGTATAACTAGTAAGGAATCCAAGCTTAAATATGAAAAAGAGTCTGGTGCTTTAAATGAATC
CTTCTCTGATATTATGGGCGTAGCTATAGAAGGAAAAAATTTCCAAATAGGTGAAGACTGCTACACACCAAATATTCCTG
GAGATGCATTGAGAGATATGGAAGACCCATCTAAAGGAAATCAACCAGCTCATATGAAAGATTTTCAATATCTTCCTAAT
GATAAAGACAATGATTGGGGTGGAGTTCATACAAATTCAGGTATAATAAATCATGCTGCTTATTTAATTGCAGTTGGAAT
GGAAAAATCCGGTGAGTCAAATAGTAAAGATATTATGGCAAATTTATTTTATAAAGCAAATTGCCATTACTGGGATGAAA
CAACAGACTTTGCTAAATGCAGAAATGATGTAGTTCAAGTTGCTAAAGATCTTTATGGAGAAAATAGTAAATATGTTAAA
ATTGTAGAAAATGCTTTTGATCAAGTTGGAATAACTGCTACACCTCAATTACCATTATAA

Upstream 100 bases:

>100_bases
TAATTGGTTAATATGTGAAATTGTTATTCATTTTCAATATTGATATAATTAATATTGAAAATTCCAATTAACCATAAATT
TGCTAGGGGGTTATTTATTT

Downstream 100 bases:

>100_bases
TTAAAAATATTTTAATTATATAAAAATTTTTATATAAAATTATAAACCTATTAATATTTTACTATATAAATATTAATAGG
TTTATAAGTAAAAATATGCT

Product: bacillolysin

Products: NA

Alternate protein names: Neutral protease [H]

Number of amino acids: Translated: 579; Mature: 579

Protein sequence:

>579_residues
MKSKKLLATVLSAVITFSTVSAVYAAPVGKENKSEPKTTTIFWENNTQNTRKATTGITQEKFNNSQDITNFFEKNISKFG
VKKGSLKNTKVVKDDKGKTNYHMIYQVDDIPVYYGRIVFTTKKDSSIDSITGRIDATFENDSWKDKVKLSKDNAIEKAKD
SIKCDSLSKTNADLYLYNFEGKPYVAYLVNLVADNGDWNVFVNAEDGSIVNQFNNTPTLIDNKDEDLPNAEEIKKASKEP
ANINSVINVNGETVKGQGKTTLDGIVDIDLTYKDGKYYLKDSNKNVYLYDVNHSLTPMYSRFKDRILRHSTLVENNSNKF
TSDEHVTAVDGYVNLSKTYDYYKNKFNRNSIDNNGMNVEGFIHTGVKYNNAFWRDDLGSMFFGDGDGVKFSSFASALDVV
GHEVSHGITSKESKLKYEKESGALNESFSDIMGVAIEGKNFQIGEDCYTPNIPGDALRDMEDPSKGNQPAHMKDFQYLPN
DKDNDWGGVHTNSGIINHAAYLIAVGMEKSGESNSKDIMANLFYKANCHYWDETTDFAKCRNDVVQVAKDLYGENSKYVK
IVENAFDQVGITATPQLPL

Sequences:

>Translated_579_residues
MKSKKLLATVLSAVITFSTVSAVYAAPVGKENKSEPKTTTIFWENNTQNTRKATTGITQEKFNNSQDITNFFEKNISKFG
VKKGSLKNTKVVKDDKGKTNYHMIYQVDDIPVYYGRIVFTTKKDSSIDSITGRIDATFENDSWKDKVKLSKDNAIEKAKD
SIKCDSLSKTNADLYLYNFEGKPYVAYLVNLVADNGDWNVFVNAEDGSIVNQFNNTPTLIDNKDEDLPNAEEIKKASKEP
ANINSVINVNGETVKGQGKTTLDGIVDIDLTYKDGKYYLKDSNKNVYLYDVNHSLTPMYSRFKDRILRHSTLVENNSNKF
TSDEHVTAVDGYVNLSKTYDYYKNKFNRNSIDNNGMNVEGFIHTGVKYNNAFWRDDLGSMFFGDGDGVKFSSFASALDVV
GHEVSHGITSKESKLKYEKESGALNESFSDIMGVAIEGKNFQIGEDCYTPNIPGDALRDMEDPSKGNQPAHMKDFQYLPN
DKDNDWGGVHTNSGIINHAAYLIAVGMEKSGESNSKDIMANLFYKANCHYWDETTDFAKCRNDVVQVAKDLYGENSKYVK
IVENAFDQVGITATPQLPL
>Mature_579_residues
MKSKKLLATVLSAVITFSTVSAVYAAPVGKENKSEPKTTTIFWENNTQNTRKATTGITQEKFNNSQDITNFFEKNISKFG
VKKGSLKNTKVVKDDKGKTNYHMIYQVDDIPVYYGRIVFTTKKDSSIDSITGRIDATFENDSWKDKVKLSKDNAIEKAKD
SIKCDSLSKTNADLYLYNFEGKPYVAYLVNLVADNGDWNVFVNAEDGSIVNQFNNTPTLIDNKDEDLPNAEEIKKASKEP
ANINSVINVNGETVKGQGKTTLDGIVDIDLTYKDGKYYLKDSNKNVYLYDVNHSLTPMYSRFKDRILRHSTLVENNSNKF
TSDEHVTAVDGYVNLSKTYDYYKNKFNRNSIDNNGMNVEGFIHTGVKYNNAFWRDDLGSMFFGDGDGVKFSSFASALDVV
GHEVSHGITSKESKLKYEKESGALNESFSDIMGVAIEGKNFQIGEDCYTPNIPGDALRDMEDPSKGNQPAHMKDFQYLPN
DKDNDWGGVHTNSGIINHAAYLIAVGMEKSGESNSKDIMANLFYKANCHYWDETTDFAKCRNDVVQVAKDLYGENSKYVK
IVENAFDQVGITATPQLPL

Specific function: Extracellular zinc metalloprotease [H]

COG id: COG3227

COG function: function code E; Zinc metalloprotease (elastase)

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M4 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005075
- InterPro:   IPR013856
- InterPro:   IPR001570
- InterPro:   IPR011096 [H]

Pfam domain/function: PF07504 FTP; PF03413 PepSY; PF01447 Peptidase_M4; PF02868 Peptidase_M4_C [H]

EC number: =3.4.24.28 [H]

Molecular weight: Translated: 64862; Mature: 64862

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSKKLLATVLSAVITFSTVSAVYAAPVGKENKSEPKTTTIFWENNTQNTRKATTGITQE
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCHHHHCCCCHH
KFNNSQDITNFFEKNISKFGVKKGSLKNTKVVKDDKGKTNYHMIYQVDDIPVYYGRIVFT
HCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCEEEEEEECCCEEEEEEEEEE
TKKDSSIDSITGRIDATFENDSWKDKVKLSKDNAIEKAKDSIKCDSLSKTNADLYLYNFE
ECCCCCCHHHCCEEEEEECCCCCCCCEEECCCHHHHHHHHCCCCCCCCCCCCEEEEEEEC
GKPYVAYLVNLVADNGDWNVFVNAEDGSIVNQFNNTPTLIDNKDEDLPNAEEIKKASKEP
CCCHHHEEEEHHCCCCCEEEEEECCCCCHHHHCCCCCCEECCCCCCCCCHHHHHHHCCCC
ANINSVINVNGETVKGQGKTTLDGIVDIDLTYKDGKYYLKDSNKNVYLYDVNHSLTPMYS
CCCCEEEECCCCEEECCCCEEECCEEEEEEEEECCEEEEEECCCEEEEEECCCCCCHHHH
RFKDRILRHSTLVENNSNKFTSDEHVTAVDGYVNLSKTYDYYKNKFNRNSIDNNGMNVEG
HHHHHHHHHHHHEECCCCCCCCCCCEEEECCEEECHHHHHHHHCCCCCCCCCCCCCEEEE
FIHTGVKYNNAFWRDDLGSMFFGDGDGVKFSSFASALDVVGHEVSHGITSKESKLKYEKE
EEECCEEECCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHCEECHH
SGALNESFSDIMGVAIEGKNFQIGEDCYTPNIPGDALRDMEDPSKGNQPAHMKDFQYLPN
CCCCCCCHHHHEEEEEECCCEEECCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCC
DKDNDWGGVHTNSGIINHAAYLIAVGMEKSGESNSKDIMANLFYKANCHYWDETTDFAKC
CCCCCCCCEECCCCHHHHEEEEEEEECCCCCCCCCHHHEEEEEEEECCEECCCCCHHHHH
RNDVVQVAKDLYGENSKYVKIVENAFDQVGITATPQLPL
HHHHHHHHHHHHCCCCCEEEEEHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MKSKKLLATVLSAVITFSTVSAVYAAPVGKENKSEPKTTTIFWENNTQNTRKATTGITQE
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCHHHHCCCCHH
KFNNSQDITNFFEKNISKFGVKKGSLKNTKVVKDDKGKTNYHMIYQVDDIPVYYGRIVFT
HCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCEEEEEEECCCEEEEEEEEEE
TKKDSSIDSITGRIDATFENDSWKDKVKLSKDNAIEKAKDSIKCDSLSKTNADLYLYNFE
ECCCCCCHHHCCEEEEEECCCCCCCCEEECCCHHHHHHHHCCCCCCCCCCCCEEEEEEEC
GKPYVAYLVNLVADNGDWNVFVNAEDGSIVNQFNNTPTLIDNKDEDLPNAEEIKKASKEP
CCCHHHEEEEHHCCCCCEEEEEECCCCCHHHHCCCCCCEECCCCCCCCCHHHHHHHCCCC
ANINSVINVNGETVKGQGKTTLDGIVDIDLTYKDGKYYLKDSNKNVYLYDVNHSLTPMYS
CCCCEEEECCCCEEECCCCEEECCEEEEEEEEECCEEEEEECCCEEEEEECCCCCCHHHH
RFKDRILRHSTLVENNSNKFTSDEHVTAVDGYVNLSKTYDYYKNKFNRNSIDNNGMNVEG
HHHHHHHHHHHHEECCCCCCCCCCCEEEECCEEECHHHHHHHHCCCCCCCCCCCCCEEEE
FIHTGVKYNNAFWRDDLGSMFFGDGDGVKFSSFASALDVVGHEVSHGITSKESKLKYEKE
EEECCEEECCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHCEECHH
SGALNESFSDIMGVAIEGKNFQIGEDCYTPNIPGDALRDMEDPSKGNQPAHMKDFQYLPN
CCCCCCCHHHHEEEEEECCCEEECCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCC
DKDNDWGGVHTNSGIINHAAYLIAVGMEKSGESNSKDIMANLFYKANCHYWDETTDFAKC
CCCCCCCCEECCCCHHHHEEEEEEEECCCCCCCCCHHHEEEEEEEECCEECCCCCHHHHH
RNDVVQVAKDLYGENSKYVKIVENAFDQVGITATPQLPL
HHHHHHHHHHHHCCCCCEEEEEHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7764969 [H]