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The map label for this gene is argS [H]

Identifier: 226948350

GI number: 226948350

Start: 1284158

End: 1285849

Strand: Direct

Name: argS [H]

Synonym: CLM_1232

Alternate gene names: 226948350

Gene position: 1284158-1285849 (Clockwise)

Preceding gene: 226948349

Following gene: 226948351

Centisome position: 30.9

GC content: 29.96

Gene sequence:

>1692_bases
ATGGATTACAAAAATCTAGTAGCTGAAAGAATAAAAGAAAATACAGAATTAGAAGTTGATTTAATAGAAAAACTTATAGA
GATTCCACCAAAGAAAGAAATGGGAGATTATGCTTTCCCATGCTTCCAATTAGCTAAAACTTTTAGAAAAGCACCAAATT
TAATAGCAGAAGAATTAAAAGAAAAAATAAATAAAGAAGGTTTTGAAAAGGTAGTAACTGTAGGACCTTATTTAAATTTC
TTTGTAGATAAAACTATACTCATAAAAGACGTATTAGAAAAAGTTTTAAGTGAAAAAGAAAAATACGGTTCTTCTAAAGT
AGGAGAAGGAAAAAATGTAGTAGTTGAATATTCATCACCAAACATTGCGAAACCATTCCATATAGGGCATTTATTTACCA
CAGCTATAGGTAATGCACTATATAAAATACTATCCTTTGAAGGTTATAATTGTATAGGAATTAACCATCTAGGAGATTGG
GGAACACAATTTGGTAAACTTATTTCTGCATATAGAAGATGGGTAGATGAAGAAGCACTAGAAAAGGATGCTATAGGAGA
ACTCTTAAGAATATATGTTAAATTTCATGAAGAAGCAGAAAAAGACCCTGAACTTGAAAAAGAAGCTAGATTAAACTTTA
AAAGACTAGAGGAAGGTTCTGAGGAAGAAACTGAATTATGGAATAGATTTAAAGATCTAAGCTTAAAAGAATTTAACAAG
GTTTATGACATGCTAGGAATAAAATTTGACTCTCTTGCAGGAGAAAGTTTCTATAGTGATAAAATGGATGCAGTAGTTCA
AGAAATAGATGATAAAGGATTATTAGTAGATAGCAATGGTGCAAAGGTAGTTATGCTTGATGAATATAATATGCCACCTT
GCATGATTAAAAAATCTGATGGAGCAACTATTTATGCTACTCGTGATTTAGCAGCAGCTATATACAGAAAGAAAACTTAT
GATTTCCACAAATGTATATATGTAGTTGGAACTCCTCAAGCACTACATTTTAAACAAGTATTTACTACTTTAAAACTTAT
GGGACACGATTGGGCAGATGATTGCAAACATGTAGGCTTTGGTCTTGTTAAATTAGCAAATAAAAAGCTATCTACAAGAA
ATGGAGATGTTGTATTCTTAGAAGACTTGTTAAATCAATCTGTAGAAGAAACATTAAAAATTATAAATGAGAAAAATCCT
AATTTGAAAAACAAAGAAGATGTGGCTAAAAAACTTGGTATAGGTGCAGTTGTATTCACATATCTAAAAAACAATAGAGA
AAGAGATATTGTATTTGATTGGAAGGAAATTCTATCATTTGATGGAGAAACAGGACCTTATGTAGAATATAGCTATGCAA
GAGGAAAGAGTATATTAAGAAAAGCAGGAGAATTAACTGGAGAAGCAGATTATTCTAAATTATCATCTAAAGAAGAGTTT
GAATTAGCAAAACTTCTTGGAGGCTTTAATGATGCTATAATGAATGCTATAGATAAATTAGAACCAGCTATGGTAACTAG
ATATATAATTGAAGTAGCAAAAGCTTTTAACAAATTCTATAATGCCCATGGTATATTAAATGCAGAAGATAATGATGTAA
AATTAGCAAGGGTAAAACTTGTAGAAGCTACTTGTCAAGTAATAAAGAATGCTCTTAACCTATTAGGTATAGATGTAGTT
GAAGAAATGTAA

Upstream 100 bases:

>100_bases
ATATAAAAAATTAAAAATGCTGTTAAATGAATAAATTAATTTTAAATATTAAAATCCTATAATGAAACTTAAATATAAAA
ACTTGGAGGTAGATTAAACT

Downstream 100 bases:

>100_bases
AAAATAAAGTAAATAATTTATTGAAGAGGGTGTCTTAAAAATAGAATAGATTTAATTTTAACACCGCAAAGATAAAAAAT
ACACTTATAAATCAATTCAT

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS [H]

Number of amino acids: Translated: 563; Mature: 563

Protein sequence:

>563_residues
MDYKNLVAERIKENTELEVDLIEKLIEIPPKKEMGDYAFPCFQLAKTFRKAPNLIAEELKEKINKEGFEKVVTVGPYLNF
FVDKTILIKDVLEKVLSEKEKYGSSKVGEGKNVVVEYSSPNIAKPFHIGHLFTTAIGNALYKILSFEGYNCIGINHLGDW
GTQFGKLISAYRRWVDEEALEKDAIGELLRIYVKFHEEAEKDPELEKEARLNFKRLEEGSEEETELWNRFKDLSLKEFNK
VYDMLGIKFDSLAGESFYSDKMDAVVQEIDDKGLLVDSNGAKVVMLDEYNMPPCMIKKSDGATIYATRDLAAAIYRKKTY
DFHKCIYVVGTPQALHFKQVFTTLKLMGHDWADDCKHVGFGLVKLANKKLSTRNGDVVFLEDLLNQSVEETLKIINEKNP
NLKNKEDVAKKLGIGAVVFTYLKNNRERDIVFDWKEILSFDGETGPYVEYSYARGKSILRKAGELTGEADYSKLSSKEEF
ELAKLLGGFNDAIMNAIDKLEPAMVTRYIIEVAKAFNKFYNAHGILNAEDNDVKLARVKLVEATCQVIKNALNLLGIDVV
EEM

Sequences:

>Translated_563_residues
MDYKNLVAERIKENTELEVDLIEKLIEIPPKKEMGDYAFPCFQLAKTFRKAPNLIAEELKEKINKEGFEKVVTVGPYLNF
FVDKTILIKDVLEKVLSEKEKYGSSKVGEGKNVVVEYSSPNIAKPFHIGHLFTTAIGNALYKILSFEGYNCIGINHLGDW
GTQFGKLISAYRRWVDEEALEKDAIGELLRIYVKFHEEAEKDPELEKEARLNFKRLEEGSEEETELWNRFKDLSLKEFNK
VYDMLGIKFDSLAGESFYSDKMDAVVQEIDDKGLLVDSNGAKVVMLDEYNMPPCMIKKSDGATIYATRDLAAAIYRKKTY
DFHKCIYVVGTPQALHFKQVFTTLKLMGHDWADDCKHVGFGLVKLANKKLSTRNGDVVFLEDLLNQSVEETLKIINEKNP
NLKNKEDVAKKLGIGAVVFTYLKNNRERDIVFDWKEILSFDGETGPYVEYSYARGKSILRKAGELTGEADYSKLSSKEEF
ELAKLLGGFNDAIMNAIDKLEPAMVTRYIIEVAKAFNKFYNAHGILNAEDNDVKLARVKLVEATCQVIKNALNLLGIDVV
EEM
>Mature_563_residues
MDYKNLVAERIKENTELEVDLIEKLIEIPPKKEMGDYAFPCFQLAKTFRKAPNLIAEELKEKINKEGFEKVVTVGPYLNF
FVDKTILIKDVLEKVLSEKEKYGSSKVGEGKNVVVEYSSPNIAKPFHIGHLFTTAIGNALYKILSFEGYNCIGINHLGDW
GTQFGKLISAYRRWVDEEALEKDAIGELLRIYVKFHEEAEKDPELEKEARLNFKRLEEGSEEETELWNRFKDLSLKEFNK
VYDMLGIKFDSLAGESFYSDKMDAVVQEIDDKGLLVDSNGAKVVMLDEYNMPPCMIKKSDGATIYATRDLAAAIYRKKTY
DFHKCIYVVGTPQALHFKQVFTTLKLMGHDWADDCKHVGFGLVKLANKKLSTRNGDVVFLEDLLNQSVEETLKIINEKNP
NLKNKEDVAKKLGIGAVVFTYLKNNRERDIVFDWKEILSFDGETGPYVEYSYARGKSILRKAGELTGEADYSKLSSKEEF
ELAKLLGGFNDAIMNAIDKLEPAMVTRYIIEVAKAFNKFYNAHGILNAEDNDVKLARVKLVEATCQVIKNALNLLGIDVV
EEM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI197100773, Length=555, Percent_Identity=34.4144144144144, Blast_Score=314, Evalue=1e-85,
Organism=Homo sapiens, GI15149476, Length=609, Percent_Identity=30.3776683087028, Blast_Score=238, Evalue=1e-62,
Organism=Escherichia coli, GI1788184, Length=562, Percent_Identity=32.7402135231317, Blast_Score=291, Evalue=6e-80,
Organism=Caenorhabditis elegans, GI71985061, Length=571, Percent_Identity=30.4728546409807, Blast_Score=209, Evalue=3e-54,
Organism=Caenorhabditis elegans, GI71985068, Length=539, Percent_Identity=30.7977736549165, Blast_Score=199, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI17532153, Length=501, Percent_Identity=27.1457085828343, Blast_Score=169, Evalue=5e-42,
Organism=Saccharomyces cerevisiae, GI6320548, Length=578, Percent_Identity=36.5051903114187, Blast_Score=352, Evalue=1e-97,
Organism=Saccharomyces cerevisiae, GI6321883, Length=575, Percent_Identity=34.0869565217391, Blast_Score=345, Evalue=8e-96,
Organism=Drosophila melanogaster, GI28571570, Length=590, Percent_Identity=28.8135593220339, Blast_Score=233, Evalue=2e-61,
Organism=Drosophila melanogaster, GI18859963, Length=541, Percent_Identity=31.6081330868762, Blast_Score=219, Evalue=3e-57,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 64027; Mature: 64027

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYKNLVAERIKENTELEVDLIEKLIEIPPKKEMGDYAFPCFQLAKTFRKAPNLIAEELK
CCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHH
EKINKEGFEKVVTVGPYLNFFVDKTILIKDVLEKVLSEKEKYGSSKVGEGKNVVVEYSSP
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCC
NIAKPFHIGHLFTTAIGNALYKILSFEGYNCIGINHLGDWGTQFGKLISAYRRWVDEEAL
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
EKDAIGELLRIYVKFHEEAEKDPELEKEARLNFKRLEEGSEEETELWNRFKDLSLKEFNK
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCHHHHHCCCHHHHHHHHHHHCCCHHHHHH
VYDMLGIKFDSLAGESFYSDKMDAVVQEIDDKGLLVDSNGAKVVMLDEYNMPPCMIKKSD
HHHHHCCCHHHHCCCCHHHHHHHHHHHHHCCCCEEEECCCCEEEEEECCCCCCCEEECCC
GATIYATRDLAAAIYRKKTYDFHKCIYVVGTPQALHFKQVFTTLKLMGHDWADDCKHVGF
CCEEEEHHHHHHHHHHHHCCCHHHEEEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHH
GLVKLANKKLSTRNGDVVFLEDLLNQSVEETLKIINEKNPNLKNKEDVAKKLGIGAVVFT
HHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHH
YLKNNRERDIVFDWKEILSFDGETGPYVEYSYARGKSILRKAGELTGEADYSKLSSKEEF
HHHCCCCCCEEECHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHCCCCCHHHHCCCHHHH
ELAKLLGGFNDAIMNAIDKLEPAMVTRYIIEVAKAFNKFYNAHGILNAEDNDVKLARVKL
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHH
VEATCQVIKNALNLLGIDVVEEM
HHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDYKNLVAERIKENTELEVDLIEKLIEIPPKKEMGDYAFPCFQLAKTFRKAPNLIAEELK
CCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHH
EKINKEGFEKVVTVGPYLNFFVDKTILIKDVLEKVLSEKEKYGSSKVGEGKNVVVEYSSP
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCC
NIAKPFHIGHLFTTAIGNALYKILSFEGYNCIGINHLGDWGTQFGKLISAYRRWVDEEAL
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
EKDAIGELLRIYVKFHEEAEKDPELEKEARLNFKRLEEGSEEETELWNRFKDLSLKEFNK
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCHHHHHCCCHHHHHHHHHHHCCCHHHHHH
VYDMLGIKFDSLAGESFYSDKMDAVVQEIDDKGLLVDSNGAKVVMLDEYNMPPCMIKKSD
HHHHHCCCHHHHCCCCHHHHHHHHHHHHHCCCCEEEECCCCEEEEEECCCCCCCEEECCC
GATIYATRDLAAAIYRKKTYDFHKCIYVVGTPQALHFKQVFTTLKLMGHDWADDCKHVGF
CCEEEEHHHHHHHHHHHHCCCHHHEEEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHH
GLVKLANKKLSTRNGDVVFLEDLLNQSVEETLKIINEKNPNLKNKEDVAKKLGIGAVVFT
HHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHH
YLKNNRERDIVFDWKEILSFDGETGPYVEYSYARGKSILRKAGELTGEADYSKLSSKEEF
HHHCCCCCCEEECHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHCCCCCHHHHCCCHHHH
ELAKLLGGFNDAIMNAIDKLEPAMVTRYIIEVAKAFNKFYNAHGILNAEDNDVKLARVKL
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHH
VEATCQVIKNALNLLGIDVVEEM
HHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA