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The map label for this gene is yfmR [H]

Identifier: 226948342

GI number: 226948342

Start: 1273207

End: 1275126

Strand: Reverse

Name: yfmR [H]

Synonym: CLM_1224

Alternate gene names: 226948342

Gene position: 1275126-1273207 (Counterclockwise)

Preceding gene: 226948353

Following gene: 226948339

Centisome position: 30.69

GC content: 28.59

Gene sequence:

>1920_bases
ATGATTATAGTAACTGTTGAAAATATATGTAAAAGTTATGGTGAAAAAACTTTATTTAAAGATGTTTCTTTTACCATAAG
CGATGAAGATAAAATAGGGTTAATAGGAGTTAACGGTACAGGAAAGTCTTCTCTTTTAAAAATTGTTACCGGTGAAGATA
GCCCTGATGGCGGTACTATTACTATTCCTAAGGGAGCTACCATTGAATATTTAGATCAAAATCCAGATTTAGATCCTAAT
GCTACAATATTAGAACAAGTATTTAAAGGTAATTCTAAAATAATGTCTGTAATAGGTGAATATGAAAAAGCTTTAGACCT
GCTTTCTAAAAATCCTGAGGATGAAAAACTGCAAAATCATTTATTAACATTAACTAGTGAAATGGATTCCTTAGATGCCT
GGGATCTTGAAAGCAAAATCAAAACCGTTCTTACTAAACTTAATGTAACAGACTTTGATAAAAAAATAAAAGAGCTTTCT
GGTGGACAAAAGAAAAGAGTCGCCTTGTGCAGCGCTTTAATATCTCCTTGCGATTTGCTTGTATTAGATGAACCAACAAA
CCACATGGATAATGATACTATAGATTGGCTTGAAAATTATCTGCAAACTAGAAAAGGTGCCCTTTTAATGGTAACCCATG
ACAGATATTTTCTAGATAGAGTTGTTAATAAAACTTTAGAATTAGACTACGGAACTATGTACACTTACAATTGTAATTAT
TCACAATTTGTAGAAAAGAAAGCAGAAAGAAAAGCATTAGAAAATTCATTAGAAGAAAAAAGACAAAGTCTTTATAAAAA
AGAATTAGAATGGATTAGAGCTGGGGTTCAGGCAAGAGGCACCAAACAAAAAGCAAGAATAAAAAGATTTGAAGAATTAG
AAGCAAGCAATTTTAACCATAATAGTAATGATATAGATATATCTGTAGCTCATTCAAGATTAGGTAAAAAAATAATTAAT
ATAGAAAACCTAACTAAAAAATTTGAAGAAAAAACTTTAATAAAAGACTTTAATTACATTTTACTTAGGAATGATCGCAT
TGGTATAGTGGGAAACAATGGAATGGGTAAGTCTACCCTTTTAAATATTATTACAAATAAAATAAATTCAGATAGTGGTT
CTATTGATATAGGTACTACAGTAAATATTGCATATTTCTCGCAGCATTCAGAGGATATAGATCCAAATTTAAGAGCTATA
GAATATATAAGAGAAACAGCAGAATTTATAACCACAGCAGATGGAACTAAAATAAGTGCCTCTCAAATGATGGAAAGATT
TCTTTTCACAGATGATATGCAATGGTGCTATATTTCAAAACTATCCGGTGGAGAAAAAAGAAGACTATATCTTTTAAAAA
TCTTAATGACTGCACCTAATGTACTTATATTGGATGAACCAACTAATGATCTAGATATTGATACATTAAAAGTTTTAGAA
AACTATATTGATGAATTTAATGGTCCAGTTATATCCGTATCCCATGATAGATACTTTTTAGATAGAATCTGTAATAAAAT
CCTTCACTTTGAAGGTAACGGAAAAATTTCTGAGTACATAGGAAACTATTCAGACTTTATATATAGGAAAAAAGAGATCT
CAAATATAACTTCAAAAGAAGAAAAAACAAATAAAGCTTTAAAAGAAAACAATATTCAAAAGGAAAAAACATCAAAATTA
AAATTCTCTTATAAAGAAAAACTTGAATACGAAAATATAGATAAAGAAATAGAAAAACTAGAAGAAAAATTATCTAAACT
AGAAGAAGAAGTAGAAATAAATGCCTCCGACTTTATGAGACTTGAAGATCTTTTAAAAGAGAAGGATAAAGTTGAGGAAG
AACTATTATTTAAAATGGAAAGACAAGAATACTTAGAAAATCTAGCAAAAGAAATAGAGGAAAATAAAAAAACTGTGTAA

Upstream 100 bases:

>100_bases
ATACAATCTATTTTGCAATATTTATGTTTTACTATAAATGTTTTTTATAATAGAATATACATCATAGAGTATAAATTAAA
TTAACAAAAGGATGATTTTA

Downstream 100 bases:

>100_bases
GTAAGTTATGCTACCCGTGGTTTTAAAAACGGATATGTGCTTATAAAGGCAACTCACTTCAATAAGAGATTCTAATTTGT
TTTTTCTTAAAATATATGGC

Product: drug resistance ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 639; Mature: 639

Protein sequence:

>639_residues
MIIVTVENICKSYGEKTLFKDVSFTISDEDKIGLIGVNGTGKSSLLKIVTGEDSPDGGTITIPKGATIEYLDQNPDLDPN
ATILEQVFKGNSKIMSVIGEYEKALDLLSKNPEDEKLQNHLLTLTSEMDSLDAWDLESKIKTVLTKLNVTDFDKKIKELS
GGQKKRVALCSALISPCDLLVLDEPTNHMDNDTIDWLENYLQTRKGALLMVTHDRYFLDRVVNKTLELDYGTMYTYNCNY
SQFVEKKAERKALENSLEEKRQSLYKKELEWIRAGVQARGTKQKARIKRFEELEASNFNHNSNDIDISVAHSRLGKKIIN
IENLTKKFEEKTLIKDFNYILLRNDRIGIVGNNGMGKSTLLNIITNKINSDSGSIDIGTTVNIAYFSQHSEDIDPNLRAI
EYIRETAEFITTADGTKISASQMMERFLFTDDMQWCYISKLSGGEKRRLYLLKILMTAPNVLILDEPTNDLDIDTLKVLE
NYIDEFNGPVISVSHDRYFLDRICNKILHFEGNGKISEYIGNYSDFIYRKKEISNITSKEEKTNKALKENNIQKEKTSKL
KFSYKEKLEYENIDKEIEKLEEKLSKLEEEVEINASDFMRLEDLLKEKDKVEEELLFKMERQEYLENLAKEIEENKKTV

Sequences:

>Translated_639_residues
MIIVTVENICKSYGEKTLFKDVSFTISDEDKIGLIGVNGTGKSSLLKIVTGEDSPDGGTITIPKGATIEYLDQNPDLDPN
ATILEQVFKGNSKIMSVIGEYEKALDLLSKNPEDEKLQNHLLTLTSEMDSLDAWDLESKIKTVLTKLNVTDFDKKIKELS
GGQKKRVALCSALISPCDLLVLDEPTNHMDNDTIDWLENYLQTRKGALLMVTHDRYFLDRVVNKTLELDYGTMYTYNCNY
SQFVEKKAERKALENSLEEKRQSLYKKELEWIRAGVQARGTKQKARIKRFEELEASNFNHNSNDIDISVAHSRLGKKIIN
IENLTKKFEEKTLIKDFNYILLRNDRIGIVGNNGMGKSTLLNIITNKINSDSGSIDIGTTVNIAYFSQHSEDIDPNLRAI
EYIRETAEFITTADGTKISASQMMERFLFTDDMQWCYISKLSGGEKRRLYLLKILMTAPNVLILDEPTNDLDIDTLKVLE
NYIDEFNGPVISVSHDRYFLDRICNKILHFEGNGKISEYIGNYSDFIYRKKEISNITSKEEKTNKALKENNIQKEKTSKL
KFSYKEKLEYENIDKEIEKLEEKLSKLEEEVEINASDFMRLEDLLKEKDKVEEELLFKMERQEYLENLAKEIEENKKTV
>Mature_639_residues
MIIVTVENICKSYGEKTLFKDVSFTISDEDKIGLIGVNGTGKSSLLKIVTGEDSPDGGTITIPKGATIEYLDQNPDLDPN
ATILEQVFKGNSKIMSVIGEYEKALDLLSKNPEDEKLQNHLLTLTSEMDSLDAWDLESKIKTVLTKLNVTDFDKKIKELS
GGQKKRVALCSALISPCDLLVLDEPTNHMDNDTIDWLENYLQTRKGALLMVTHDRYFLDRVVNKTLELDYGTMYTYNCNY
SQFVEKKAERKALENSLEEKRQSLYKKELEWIRAGVQARGTKQKARIKRFEELEASNFNHNSNDIDISVAHSRLGKKIIN
IENLTKKFEEKTLIKDFNYILLRNDRIGIVGNNGMGKSTLLNIITNKINSDSGSIDIGTTVNIAYFSQHSEDIDPNLRAI
EYIRETAEFITTADGTKISASQMMERFLFTDDMQWCYISKLSGGEKRRLYLLKILMTAPNVLILDEPTNDLDIDTLKVLE
NYIDEFNGPVISVSHDRYFLDRICNKILHFEGNGKISEYIGNYSDFIYRKKEISNITSKEEKTNKALKENNIQKEKTSKL
KFSYKEKLEYENIDKEIEKLEEKLSKLEEEVEINASDFMRLEDLLKEKDKVEEELLFKMERQEYLENLAKEIEENKKTV

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=540, Percent_Identity=26.4814814814815, Blast_Score=202, Evalue=9e-52,
Organism=Homo sapiens, GI27881506, Length=519, Percent_Identity=28.9017341040462, Blast_Score=178, Evalue=2e-44,
Organism=Homo sapiens, GI10947137, Length=519, Percent_Identity=28.9017341040462, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI10947135, Length=552, Percent_Identity=26.8115942028986, Blast_Score=162, Evalue=1e-39,
Organism=Homo sapiens, GI69354671, Length=552, Percent_Identity=26.8115942028986, Blast_Score=162, Evalue=1e-39,
Organism=Homo sapiens, GI153792144, Length=198, Percent_Identity=31.3131313131313, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI2367384, Length=545, Percent_Identity=36.1467889908257, Blast_Score=357, Evalue=1e-100,
Organism=Escherichia coli, GI1787182, Length=636, Percent_Identity=32.3899371069182, Blast_Score=340, Evalue=1e-94,
Organism=Escherichia coli, GI1789751, Length=674, Percent_Identity=30.1186943620178, Blast_Score=292, Evalue=5e-80,
Organism=Escherichia coli, GI1787041, Length=541, Percent_Identity=29.7597042513863, Blast_Score=247, Evalue=1e-66,
Organism=Escherichia coli, GI48994943, Length=485, Percent_Identity=22.680412371134, Blast_Score=95, Evalue=2e-20,
Organism=Escherichia coli, GI1790525, Length=565, Percent_Identity=22.8318584070796, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1788506, Length=557, Percent_Identity=20.8258527827648, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI87081782, Length=612, Percent_Identity=21.078431372549, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1788165, Length=239, Percent_Identity=24.6861924686192, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1789891, Length=233, Percent_Identity=27.0386266094421, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1786872, Length=252, Percent_Identity=25, Blast_Score=66, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17559834, Length=557, Percent_Identity=29.0843806104129, Blast_Score=209, Evalue=3e-54,
Organism=Caenorhabditis elegans, GI17553372, Length=517, Percent_Identity=30.174081237911, Blast_Score=207, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI17555318, Length=558, Percent_Identity=27.4193548387097, Blast_Score=180, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6320874, Length=547, Percent_Identity=29.981718464351, Blast_Score=211, Evalue=4e-55,
Organism=Saccharomyces cerevisiae, GI6321121, Length=559, Percent_Identity=27.3703041144902, Blast_Score=189, Evalue=8e-49,
Organism=Saccharomyces cerevisiae, GI6323278, Length=385, Percent_Identity=25.974025974026, Blast_Score=112, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6324314, Length=399, Percent_Identity=26.0651629072682, Blast_Score=112, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6325030, Length=425, Percent_Identity=25.1764705882353, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24666836, Length=548, Percent_Identity=30.1094890510949, Blast_Score=219, Evalue=5e-57,
Organism=Drosophila melanogaster, GI24641342, Length=556, Percent_Identity=29.136690647482, Blast_Score=195, Evalue=1e-49,
Organism=Drosophila melanogaster, GI24642252, Length=564, Percent_Identity=28.3687943262411, Blast_Score=192, Evalue=5e-49,
Organism=Drosophila melanogaster, GI18859989, Length=564, Percent_Identity=28.3687943262411, Blast_Score=192, Evalue=5e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 73460; Mature: 73460

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIVTVENICKSYGEKTLFKDVSFTISDEDKIGLIGVNGTGKSSLLKIVTGEDSPDGGTI
CEEEEHHHHHHHHCCHHHHHCCEEEECCCCCEEEEEECCCCCCCEEEEEECCCCCCCCEE
TIPKGATIEYLDQNPDLDPNATILEQVFKGNSKIMSVIGEYEKALDLLSKNPEDEKLQNH
EECCCCEEEEECCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
LLTLTSEMDSLDAWDLESKIKTVLTKLNVTDFDKKIKELSGGQKKRVALCSALISPCDLL
HHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEE
VLDEPTNHMDNDTIDWLENYLQTRKGALLMVTHDRYFLDRVVNKTLELDYGTMYTYNCNY
EECCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHEEECCCEEEEEECCH
SQFVEKKAERKALENSLEEKRQSLYKKELEWIRAGVQARGTKQKARIKRFEELEASNFNH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCC
NSNDIDISVAHSRLGKKIINIENLTKKFEEKTLIKDFNYILLRNDRIGIVGNNGMGKSTL
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCEEEEEECCCCCHHHH
LNIITNKINSDSGSIDIGTTVNIAYFSQHSEDIDPNLRAIEYIRETAEFITTADGTKISA
HHHHHHHCCCCCCCEEECCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEECH
SQMMERFLFTDDMQWCYISKLSGGEKRRLYLLKILMTAPNVLILDEPTNDLDIDTLKVLE
HHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHH
NYIDEFNGPVISVSHDRYFLDRICNKILHFEGNGKISEYIGNYSDFIYRKKEISNITSKE
HHHHHHCCCEEEEECCHHHHHHHHHHHEECCCCCCHHHHHCCHHHHHHHHHHHHHHHHHH
EKTNKALKENNIQKEKTSKLKFSYKEKLEYENIDKEIEKLEEKLSKLEEEVEINASDFMR
HHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LEDLLKEKDKVEEELLFKMERQEYLENLAKEIEENKKTV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIIVTVENICKSYGEKTLFKDVSFTISDEDKIGLIGVNGTGKSSLLKIVTGEDSPDGGTI
CEEEEHHHHHHHHCCHHHHHCCEEEECCCCCEEEEEECCCCCCCEEEEEECCCCCCCCEE
TIPKGATIEYLDQNPDLDPNATILEQVFKGNSKIMSVIGEYEKALDLLSKNPEDEKLQNH
EECCCCEEEEECCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
LLTLTSEMDSLDAWDLESKIKTVLTKLNVTDFDKKIKELSGGQKKRVALCSALISPCDLL
HHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEE
VLDEPTNHMDNDTIDWLENYLQTRKGALLMVTHDRYFLDRVVNKTLELDYGTMYTYNCNY
EECCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHEEECCCEEEEEECCH
SQFVEKKAERKALENSLEEKRQSLYKKELEWIRAGVQARGTKQKARIKRFEELEASNFNH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCC
NSNDIDISVAHSRLGKKIINIENLTKKFEEKTLIKDFNYILLRNDRIGIVGNNGMGKSTL
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCEEEEEECCCCCHHHH
LNIITNKINSDSGSIDIGTTVNIAYFSQHSEDIDPNLRAIEYIRETAEFITTADGTKISA
HHHHHHHCCCCCCCEEECCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEECH
SQMMERFLFTDDMQWCYISKLSGGEKRRLYLLKILMTAPNVLILDEPTNDLDIDTLKVLE
HHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHH
NYIDEFNGPVISVSHDRYFLDRICNKILHFEGNGKISEYIGNYSDFIYRKKEISNITSKE
HHHHHHCCCEEEEECCHHHHHHHHHHHEECCCCCCHHHHHCCHHHHHHHHHHHHHHHHHH
EKTNKALKENNIQKEKTSKLKFSYKEKLEYENIDKEIEKLEEKLSKLEEEVEINASDFMR
HHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LEDLLKEKDKVEEELLFKMERQEYLENLAKEIEENKKTV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]