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The map label for this gene is ycbL [H]

Identifier: 226948317

GI number: 226948317

Start: 1239435

End: 1240136

Strand: Direct

Name: ycbL [H]

Synonym: CLM_1197

Alternate gene names: 226948317

Gene position: 1239435-1240136 (Clockwise)

Preceding gene: 226948316

Following gene: 226948318

Centisome position: 29.83

GC content: 30.34

Gene sequence:

>702_bases
ATGAAGGAATTCTTTAAAATATTAGTTGTAGATGATGAAGAAAGGATATTAGATGTGGTAAAAGCTTATCTAGAAAAAGA
AGGTTATGAAGTGATAACTGCAATGGATGGTGAAGAAGCAATTAAGTTATTTAAAGAAATATCATTTCATTTAGTTATAT
TGGATTTAATGCTACCAAAGATATCTGGTGAAGAGGTATGTTCAAAAATAAGAGAATTTTCTAATGTTCCAATTATTATG
CTTACAGCAAAAGTAGAGGAAGAGGATAAGCTAGAAGGTCTTTCTATAGGAGCAGATGATTATCTTACAAAACCTTTTAG
TGTAAGGGAGCTTGTGGCAAGAGTAAAGGCTCTTATTAGAAGAGCCTATAGAGGAAAGTATCCATTGGCAGAGCATTTAA
TACTTAATAATGGAGACTTAGAAGTTGACATAAGAAAAATGAAAGTATTAAAAAACGGAAAGGTGGTTACATTAACACCT
TATGAGTTTAAAGTGCTTGTTTCATTATTAACTAATCCAGGACAGGTTTTTACTAGAGAACAGTTAGTTGAACAAGCTTT
TGGATATGATTATGAAAGCTTTAATAGGACTGTAGATACTTATATAAAAAATATAAGACAAAAGATAGAAGATAATCCTA
AAGCACCTAACTATATTACTACTGTATATGGAGTTGGATACAGATTTGGAGGAAAAAATTAA

Upstream 100 bases:

>100_bases
GCTGAAGAGTTCTAATACATACTAAGTTTATAAACATTAAGAACATTATCAATAATGGTAATGGGATGGAATTTAAATAT
AAATGGTTAGGAGAGAAGAT

Downstream 100 bases:

>100_bases
TGAAAATGTCTTTAAAGAAAAAACTTTCTTTAGGATTTTTAATTGCGGTTATAGGTTCAATAATAATTGCTAGTTCCATA
TCTAATTATATGATAAATAA

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MKEFFKILVVDDEERILDVVKAYLEKEGYEVITAMDGEEAIKLFKEISFHLVILDLMLPKISGEEVCSKIREFSNVPIIM
LTAKVEEEDKLEGLSIGADDYLTKPFSVRELVARVKALIRRAYRGKYPLAEHLILNNGDLEVDIRKMKVLKNGKVVTLTP
YEFKVLVSLLTNPGQVFTREQLVEQAFGYDYESFNRTVDTYIKNIRQKIEDNPKAPNYITTVYGVGYRFGGKN

Sequences:

>Translated_233_residues
MKEFFKILVVDDEERILDVVKAYLEKEGYEVITAMDGEEAIKLFKEISFHLVILDLMLPKISGEEVCSKIREFSNVPIIM
LTAKVEEEDKLEGLSIGADDYLTKPFSVRELVARVKALIRRAYRGKYPLAEHLILNNGDLEVDIRKMKVLKNGKVVTLTP
YEFKVLVSLLTNPGQVFTREQLVEQAFGYDYESFNRTVDTYIKNIRQKIEDNPKAPNYITTVYGVGYRFGGKN
>Mature_233_residues
MKEFFKILVVDDEERILDVVKAYLEKEGYEVITAMDGEEAIKLFKEISFHLVILDLMLPKISGEEVCSKIREFSNVPIIM
LTAKVEEEDKLEGLSIGADDYLTKPFSVRELVARVKALIRRAYRGKYPLAEHLILNNGDLEVDIRKMKVLKNGKVVTLTP
YEFKVLVSLLTNPGQVFTREQLVEQAFGYDYESFNRTVDTYIKNIRQKIEDNPKAPNYITTVYGVGYRFGGKN

Specific function: Member of the two-component regulatory system ycbM/ycbL [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=232, Percent_Identity=39.2241379310345, Blast_Score=184, Evalue=6e-48,
Organism=Escherichia coli, GI1788394, Length=230, Percent_Identity=40.4347826086956, Blast_Score=172, Evalue=2e-44,
Organism=Escherichia coli, GI1786599, Length=230, Percent_Identity=37.3913043478261, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1790863, Length=230, Percent_Identity=35.6521739130435, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1786911, Length=223, Percent_Identity=35.8744394618834, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI2367329, Length=232, Percent_Identity=37.9310344827586, Blast_Score=144, Evalue=5e-36,
Organism=Escherichia coli, GI1790860, Length=227, Percent_Identity=36.1233480176211, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI87082012, Length=225, Percent_Identity=33.3333333333333, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=36.1607142857143, Blast_Score=131, Evalue=3e-32,
Organism=Escherichia coli, GI1789402, Length=229, Percent_Identity=32.7510917030568, Blast_Score=124, Evalue=4e-30,
Organism=Escherichia coli, GI1787229, Length=226, Percent_Identity=31.4159292035398, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=32.5892857142857, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1787375, Length=227, Percent_Identity=33.0396475770925, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=29.1845493562232, Blast_Score=96, Evalue=1e-21,
Organism=Escherichia coli, GI1788550, Length=202, Percent_Identity=26.2376237623762, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI48994928, Length=119, Percent_Identity=37.8151260504202, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1790437, Length=145, Percent_Identity=28.2758620689655, Blast_Score=62, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=133, Percent_Identity=28.5714285714286, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323034, Length=145, Percent_Identity=29.6551724137931, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26770; Mature: 26770

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEFFKILVVDDEERILDVVKAYLEKEGYEVITAMDGEEAIKLFKEISFHLVILDLMLPK
CCCCEEEEEECCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCC
ISGEEVCSKIREFSNVPIIMLTAKVEEEDKLEGLSIGADDYLTKPFSVRELVARVKALIR
CCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEECCHHHHCCCHHHHHHHHHHHHHHH
RAYRGKYPLAEHLILNNGDLEVDIRKMKVLKNGKVVTLTPYEFKVLVSLLTNPGQVFTRE
HHHCCCCCCHHHEEECCCCCEEEHHHHHHHCCCCEEEECCHHHHHHHHHHCCCCHHHHHH
QLVEQAFGYDYESFNRTVDTYIKNIRQKIEDNPKAPNYITTVYGVGYRFGGKN
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHEEECCEECCCCC
>Mature Secondary Structure
MKEFFKILVVDDEERILDVVKAYLEKEGYEVITAMDGEEAIKLFKEISFHLVILDLMLPK
CCCCEEEEEECCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCC
ISGEEVCSKIREFSNVPIIMLTAKVEEEDKLEGLSIGADDYLTKPFSVRELVARVKALIR
CCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEECCHHHHCCCHHHHHHHHHHHHHHH
RAYRGKYPLAEHLILNNGDLEVDIRKMKVLKNGKVVTLTPYEFKVLVSLLTNPGQVFTRE
HHHCCCCCCHHHEEECCCCCEEEHHHHHHHCCCCEEEECCHHHHHHHHHHCCCCHHHHHH
QLVEQAFGYDYESFNRTVDTYIKNIRQKIEDNPKAPNYITTVYGVGYRFGGKN
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHEEECCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]