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The map label for this gene is resE [H]

Identifier: 226948318

GI number: 226948318

Start: 1240136

End: 1241542

Strand: Direct

Name: resE [H]

Synonym: CLM_1198

Alternate gene names: 226948318

Gene position: 1240136-1241542 (Clockwise)

Preceding gene: 226948317

Following gene: 226948321

Centisome position: 29.84

GC content: 28.07

Gene sequence:

>1407_bases
ATGAAAATGTCTTTAAAGAAAAAACTTTCTTTAGGATTTTTAATTGCGGTTATAGGTTCAATAATAATTGCTAGTTCCAT
ATCTAATTATATGATAAATAACAGATTCAATGAATATTTGGTTCAAGAACATAAAAATAAAATAAATCAAATTATAGTGG
CAATTGAAGATATGTATAAAGAAGATAAAGGCTTTCAAGCATTAAAGTATGATGAAATAAAAAGATATGCAGTTTTAAAT
GAACTTTATATAGAGATAAAAGATAAAAAGGGTAGCAAGATATTTACCTCTGGGGATGACCATCTTAAACATAGGAGTAT
GATGAATTCTATGATGGGGCATGGAATGGGTAATATGATGGGAAAAATGAAAAATTTAGATTTAGGGGATTATAAAGAAG
AAGAACAATGGCTTAAAAAGAACAATGTGACTTTTGGAAAGATAACTATTGGATATTTTGGTACTTCATATTTAAGCAAT
GGAGCATTAACATTTAAAAGAACTTTAAATCATTCCTTTATTGTATCTATGGTCATAACCTTTATTTTAGGACTCATACT
GAGCTGGATTTTATCAAAACAACTTTCAAAACCGTTGGTTAAAATAAAAGAAATAGCTAATACAATGAGAATGGGCAATT
TAAATACAAGGTCTAATATAAAAAGTAATACAACAGAAATTCAGGAATTATCAAATTCTATAAATTATTTAGCAGAAACA
CTACAACAACAGGAGGCTCTTCGTAAAAGATTGACTTCAGATATGGCTCATGAAATAAGAACTCCAATTACGACTTTAAA
AACTCATGTTGAGGCAATAATAGATGGTATATGGGAACCTACAGAGGAAAGATTGCAGGTTTTTTATGAGGAATTAGAGC
GATTAACAAATCTTGTGAATAATTTAAGAAATATTTCTAAATTAGAAAAAGCCGAAACAGTTGTAAATAAAACTAACTTA
AATATTACAAAGGAAATAGAAAAAGTTGTAGAAACATTTAATCCTTTATATGAAAAAAGCGGCTTTAAAATAGTTACTAA
ACTGGAGAAGGATGTATATGGTTTTATAGATAAGGATAAATTAAAGCAAATTATGCATAATCTTTTATCTAATTCACATA
AATATTTAAATGAAGATGGATTAGTAAAGGTTTCATTATCAAAGGGAAAAGATAAAATATTTATAAAGGTTGAAGATAAT
GGAGAGGGGATTCCAAAGGAGGATTTACCTCATATATTTGAAAGATTTTATAGAAGTGATGTATCAAGGAATAAAACTAC
AGGAGGTACAGGTCTTGGTCTTACCATAACAAAAACTTTAGTAGAAGCTCATGGTGGGCATATTAGAGTAGAAAGTAAGA
TGGGAGTTGGAACCAAGTTTATTATAGAGATAAAAACTACTCTTTAG

Upstream 100 bases:

>100_bases
ATATAAAAAATATAAGACAAAAGATAGAAGATAATCCTAAAGCACCTAACTATATTACTACTGTATATGGAGTTGGATAC
AGATTTGGAGGAAAAAATTA

Downstream 100 bases:

>100_bases
ATTTAAGTTTATTGTAAAAATATTTTTATTATTTTGTCCTATAATTTTATAAAGGTTTTATCTTTTTTGTTGCTTTGCTT
TTGTTTAAGCATGAATTTTA

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MKMSLKKKLSLGFLIAVIGSIIIASSISNYMINNRFNEYLVQEHKNKINQIIVAIEDMYKEDKGFQALKYDEIKRYAVLN
ELYIEIKDKKGSKIFTSGDDHLKHRSMMNSMMGHGMGNMMGKMKNLDLGDYKEEEQWLKKNNVTFGKITIGYFGTSYLSN
GALTFKRTLNHSFIVSMVITFILGLILSWILSKQLSKPLVKIKEIANTMRMGNLNTRSNIKSNTTEIQELSNSINYLAET
LQQQEALRKRLTSDMAHEIRTPITTLKTHVEAIIDGIWEPTEERLQVFYEELERLTNLVNNLRNISKLEKAETVVNKTNL
NITKEIEKVVETFNPLYEKSGFKIVTKLEKDVYGFIDKDKLKQIMHNLLSNSHKYLNEDGLVKVSLSKGKDKIFIKVEDN
GEGIPKEDLPHIFERFYRSDVSRNKTTGGTGLGLTITKTLVEAHGGHIRVESKMGVGTKFIIEIKTTL

Sequences:

>Translated_468_residues
MKMSLKKKLSLGFLIAVIGSIIIASSISNYMINNRFNEYLVQEHKNKINQIIVAIEDMYKEDKGFQALKYDEIKRYAVLN
ELYIEIKDKKGSKIFTSGDDHLKHRSMMNSMMGHGMGNMMGKMKNLDLGDYKEEEQWLKKNNVTFGKITIGYFGTSYLSN
GALTFKRTLNHSFIVSMVITFILGLILSWILSKQLSKPLVKIKEIANTMRMGNLNTRSNIKSNTTEIQELSNSINYLAET
LQQQEALRKRLTSDMAHEIRTPITTLKTHVEAIIDGIWEPTEERLQVFYEELERLTNLVNNLRNISKLEKAETVVNKTNL
NITKEIEKVVETFNPLYEKSGFKIVTKLEKDVYGFIDKDKLKQIMHNLLSNSHKYLNEDGLVKVSLSKGKDKIFIKVEDN
GEGIPKEDLPHIFERFYRSDVSRNKTTGGTGLGLTITKTLVEAHGGHIRVESKMGVGTKFIIEIKTTL
>Mature_468_residues
MKMSLKKKLSLGFLIAVIGSIIIASSISNYMINNRFNEYLVQEHKNKINQIIVAIEDMYKEDKGFQALKYDEIKRYAVLN
ELYIEIKDKKGSKIFTSGDDHLKHRSMMNSMMGHGMGNMMGKMKNLDLGDYKEEEQWLKKNNVTFGKITIGYFGTSYLSN
GALTFKRTLNHSFIVSMVITFILGLILSWILSKQLSKPLVKIKEIANTMRMGNLNTRSNIKSNTTEIQELSNSINYLAET
LQQQEALRKRLTSDMAHEIRTPITTLKTHVEAIIDGIWEPTEERLQVFYEELERLTNLVNNLRNISKLEKAETVVNKTNL
NITKEIEKVVETFNPLYEKSGFKIVTKLEKDVYGFIDKDKLKQIMHNLLSNSHKYLNEDGLVKVSLSKGKDKIFIKVEDN
GEGIPKEDLPHIFERFYRSDVSRNKTTGGTGLGLTITKTLVEAHGGHIRVESKMGVGTKFIIEIKTTL

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=273, Percent_Identity=29.6703296703297, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1786783, Length=396, Percent_Identity=27.2727272727273, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1790346, Length=268, Percent_Identity=27.6119402985075, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1786600, Length=233, Percent_Identity=31.3304721030043, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1789149, Length=344, Percent_Identity=27.3255813953488, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1787894, Length=294, Percent_Identity=24.8299319727891, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1788713, Length=251, Percent_Identity=25.8964143426295, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI87082128, Length=299, Percent_Identity=22.742474916388, Blast_Score=89, Evalue=9e-19,
Organism=Escherichia coli, GI145693157, Length=240, Percent_Identity=22.9166666666667, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI87081816, Length=258, Percent_Identity=24.4186046511628, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1789403, Length=288, Percent_Identity=25.3472222222222, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1788279, Length=278, Percent_Identity=25.1798561151079, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI48994928, Length=284, Percent_Identity=24.6478873239437, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790551, Length=305, Percent_Identity=24.2622950819672, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1788549, Length=216, Percent_Identity=26.3888888888889, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1790436, Length=214, Percent_Identity=27.5700934579439, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1787374, Length=289, Percent_Identity=21.1072664359862, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790300, Length=252, Percent_Identity=25.7936507936508, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786912, Length=232, Percent_Identity=23.7068965517241, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1790861, Length=386, Percent_Identity=21.7616580310881, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 53534; Mature: 53534

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMSLKKKLSLGFLIAVIGSIIIASSISNYMINNRFNEYLVQEHKNKINQIIVAIEDMYK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
EDKGFQALKYDEIKRYAVLNELYIEIKDKKGSKIFTSGDDHLKHRSMMNSMMGHGMGNMM
HCCCCCHHHHHHHHHHHHHHHHHEEEECCCCCEEEECCCHHHHHHHHHHHHHHCCHHHHH
GKMKNLDLGDYKEEEQWLKKNNVTFGKITIGYFGTSYLSNGALTFKRTLNHSFIVSMVIT
HHHCCCCCCCCCHHHHHHHHCCCEEEEEEEEHHHHHHHCCCCEEHHHHHCHHHHHHHHHH
FILGLILSWILSKQLSKPLVKIKEIANTMRMGNLNTRSNIKSNTTEIQELSNSINYLAET
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
LQQQEALRKRLTSDMAHEIRTPITTLKTHVEAIIDGIWEPTEERLQVFYEELERLTNLVN
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
NLRNISKLEKAETVVNKTNLNITKEIEKVVETFNPLYEKSGFKIVTKLEKDVYGFIDKDK
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHCCCCHHH
LKQIMHNLLSNSHKYLNEDGLVKVSLSKGKDKIFIKVEDNGEGIPKEDLPHIFERFYRSD
HHHHHHHHHCCCHHHCCCCCEEEEEECCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHH
VSRNKTTGGTGLGLTITKTLVEAHGGHIRVESKMGVGTKFIIEIKTTL
CCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCEEEEEEEEECC
>Mature Secondary Structure
MKMSLKKKLSLGFLIAVIGSIIIASSISNYMINNRFNEYLVQEHKNKINQIIVAIEDMYK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
EDKGFQALKYDEIKRYAVLNELYIEIKDKKGSKIFTSGDDHLKHRSMMNSMMGHGMGNMM
HCCCCCHHHHHHHHHHHHHHHHHEEEECCCCCEEEECCCHHHHHHHHHHHHHHCCHHHHH
GKMKNLDLGDYKEEEQWLKKNNVTFGKITIGYFGTSYLSNGALTFKRTLNHSFIVSMVIT
HHHCCCCCCCCCHHHHHHHHCCCEEEEEEEEHHHHHHHCCCCEEHHHHHCHHHHHHHHHH
FILGLILSWILSKQLSKPLVKIKEIANTMRMGNLNTRSNIKSNTTEIQELSNSINYLAET
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
LQQQEALRKRLTSDMAHEIRTPITTLKTHVEAIIDGIWEPTEERLQVFYEELERLTNLVN
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
NLRNISKLEKAETVVNKTNLNITKEIEKVVETFNPLYEKSGFKIVTKLEKDVYGFIDKDK
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHCCCCHHH
LKQIMHNLLSNSHKYLNEDGLVKVSLSKGKDKIFIKVEDNGEGIPKEDLPHIFERFYRSD
HHHHHHHHHCCCHHHCCCCCEEEEEECCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHH
VSRNKTTGGTGLGLTITKTLVEAHGGHIRVESKMGVGTKFIIEIKTTL
CCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]