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The map label for this gene is pocR [H]

Identifier: 226948254

GI number: 226948254

Start: 1172848

End: 1173885

Strand: Reverse

Name: pocR [H]

Synonym: CLM_1133

Alternate gene names: 226948254

Gene position: 1173885-1172848 (Counterclockwise)

Preceding gene: 226948265

Following gene: 226948253

Centisome position: 28.25

GC content: 27.36

Gene sequence:

>1038_bases
TTGATTAAGGAAAATTTAAATTTAGATAAGGTCATAGATTTTAAAAAATGGATCAAACTACAGGAATCTTTAGCATTAGT
TACTAAAGCAGCTATTATAATCGTTGATTATAAAGGAAATCCAGTTACAGAACATAGTAGGTGTAATAGGTTCTGTAAAG
CAGTAAGATCAAATCCAAATCTTGTTAAGTATTGTCAGAAATGCGATTCAAGAGGTGGATTAGAAGCCGTTCGTTTAAAT
AAGCCATATATATACTTATGTCATTATAATATAGTGGATATAGCTATTCCAATAATTATAGATGGCAAATATATTGGTGC
AATTATGGCTGGACAAATAAAACTATCTGACAATAAGGATTCGGATTTCTTAGAACAAATAGTTATAACACCTAAAAATT
CTATGGCTAGACACGCCTTAGAAGAATTTAAAGAATATTACGATGAAATTCCTGTTTTATCCCTAAAGGAAGTGCAAGAA
ATAGCTAATATGTTATTTTCTTTATGCAATTATTTAGTAGAAGAAGCTTTAAATAAAAATTTAATTTCAGAAATATATCA
AAAAACTGTAACACCTAAATCAGAAATAGATTTAAACATCTTAACAGGATATACAATGAAAAATATTGAAAATGCAAAAA
AGGAAATGTCTAATGTTTTATTAGATTCTTATGTAAAAGAGAATCTTTCAAGTGATAGCTTAGATGTTTCAGTAAGTAAT
ACACTAAAGCCTGCTATTGAGTATATTTATAATCATAAAAGCGAAAATATTACTGCAAAAAAATTAGCAGAGGTTTGTCA
TATAAGTCCTAGTTATTTTAGTAGGCTATTTTCAAAAGAAACGGGAAAAAGCTTTTCAAGTTTTATTTCTAATCTAAAGA
TAGATTGGGCAAAAAGCTTATTAGAAGAAACAGATATGCATATAAATGAAATCAGCGACGAACTTGGCTTTAATGAGACA
GGTTATTTTATAAAAATATTCAAAAAATATGAAGGTGTAACCCCTTTTGTGTATAGAAAGTACTGTAAAAAAAATTAA

Upstream 100 bases:

>100_bases
TGATAAAATATAATATAATGATACATTATGAACAATTGCTTTATATATTTAAAAGAGTTATTTTATCAATAATATAATGA
TTTTATAGGAGCAAATAAAA

Downstream 100 bases:

>100_bases
AAGGTATCCTTTATACATCATCTCTAATTGCATTTAATTTTAATATATAAAATACATTTAATAAAACTATAAATAAGATT
TTCTAGTTCTTAATTTGGTG

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MIKENLNLDKVIDFKKWIKLQESLALVTKAAIIIVDYKGNPVTEHSRCNRFCKAVRSNPNLVKYCQKCDSRGGLEAVRLN
KPYIYLCHYNIVDIAIPIIIDGKYIGAIMAGQIKLSDNKDSDFLEQIVITPKNSMARHALEEFKEYYDEIPVLSLKEVQE
IANMLFSLCNYLVEEALNKNLISEIYQKTVTPKSEIDLNILTGYTMKNIENAKKEMSNVLLDSYVKENLSSDSLDVSVSN
TLKPAIEYIYNHKSENITAKKLAEVCHISPSYFSRLFSKETGKSFSSFISNLKIDWAKSLLEETDMHINEISDELGFNET
GYFIKIFKKYEGVTPFVYRKYCKKN

Sequences:

>Translated_345_residues
MIKENLNLDKVIDFKKWIKLQESLALVTKAAIIIVDYKGNPVTEHSRCNRFCKAVRSNPNLVKYCQKCDSRGGLEAVRLN
KPYIYLCHYNIVDIAIPIIIDGKYIGAIMAGQIKLSDNKDSDFLEQIVITPKNSMARHALEEFKEYYDEIPVLSLKEVQE
IANMLFSLCNYLVEEALNKNLISEIYQKTVTPKSEIDLNILTGYTMKNIENAKKEMSNVLLDSYVKENLSSDSLDVSVSN
TLKPAIEYIYNHKSENITAKKLAEVCHISPSYFSRLFSKETGKSFSSFISNLKIDWAKSLLEETDMHINEISDELGFNET
GYFIKIFKKYEGVTPFVYRKYCKKN
>Mature_345_residues
MIKENLNLDKVIDFKKWIKLQESLALVTKAAIIIVDYKGNPVTEHSRCNRFCKAVRSNPNLVKYCQKCDSRGGLEAVRLN
KPYIYLCHYNIVDIAIPIIIDGKYIGAIMAGQIKLSDNKDSDFLEQIVITPKNSMARHALEEFKEYYDEIPVLSLKEVQE
IANMLFSLCNYLVEEALNKNLISEIYQKTVTPKSEIDLNILTGYTMKNIENAKKEMSNVLLDSYVKENLSSDSLDVSVSN
TLKPAIEYIYNHKSENITAKKLAEVCHISPSYFSRLFSKETGKSFSSFISNLKIDWAKSLLEETDMHINEISDELGFNET
GYFIKIFKKYEGVTPFVYRKYCKKN

Specific function: Positive regulatory protein of pdu and cob operons [H]

COG id: COG4936

COG function: function code TK; Predicted sensor domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790391, Length=121, Percent_Identity=30.5785123966942, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1786251, Length=115, Percent_Identity=32.1739130434783, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR020449
- InterPro:   IPR018060
- InterPro:   IPR018771 [H]

Pfam domain/function: PF10114 Hist_Kin_Sens; PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 39609; Mature: 39609

Theoretical pI: Translated: 7.72; Mature: 7.72

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKENLNLDKVIDFKKWIKLQESLALVTKAAIIIVDYKGNPVTEHSRCNRFCKAVRSNPN
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCHHHHHHHHHHHHHCCCH
LVKYCQKCDSRGGLEAVRLNKPYIYLCHYNIVDIAIPIIIDGKYIGAIMAGQIKLSDNKD
HHHHHHHHCCCCCCEEEEECCCEEEEEECCHHHEEEEEEECCHHHHHEEECEEEECCCCC
SDFLEQIVITPKNSMARHALEEFKEYYDEIPVLSLKEVQEIANMLFSLCNYLVEEALNKN
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHH
LISEIYQKTVTPKSEIDLNILTGYTMKNIENAKKEMSNVLLDSYVKENLSSDSLDVSVSN
HHHHHHHHHCCCCHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHH
TLKPAIEYIYNHKSENITAKKLAEVCHISPSYFSRLFSKETGKSFSSFISNLKIDWAKSL
HHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHH
LEETDMHINEISDELGFNETGYFIKIFKKYEGVTPFVYRKYCKKN
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHCCC
>Mature Secondary Structure
MIKENLNLDKVIDFKKWIKLQESLALVTKAAIIIVDYKGNPVTEHSRCNRFCKAVRSNPN
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCHHHHHHHHHHHHHCCCH
LVKYCQKCDSRGGLEAVRLNKPYIYLCHYNIVDIAIPIIIDGKYIGAIMAGQIKLSDNKD
HHHHHHHHCCCCCCEEEEECCCEEEEEECCHHHEEEEEEECCHHHHHEEECEEEECCCCC
SDFLEQIVITPKNSMARHALEEFKEYYDEIPVLSLKEVQEIANMLFSLCNYLVEEALNKN
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHH
LISEIYQKTVTPKSEIDLNILTGYTMKNIENAKKEMSNVLLDSYVKENLSSDSLDVSVSN
HHHHHHHHHCCCCHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHH
TLKPAIEYIYNHKSENITAKKLAEVCHISPSYFSRLFSKETGKSFSSFISNLKIDWAKSL
HHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHH
LEETDMHINEISDELGFNETGYFIKIFKKYEGVTPFVYRKYCKKN
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8071226; 9352910; 11677609; 8501034 [H]