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The map label for this gene is add [H]

Identifier: 226948265

GI number: 226948265

Start: 1182462

End: 1183469

Strand: Reverse

Name: add [H]

Synonym: CLM_1145

Alternate gene names: 226948265

Gene position: 1183469-1182462 (Counterclockwise)

Preceding gene: 226948268

Following gene: 226948254

Centisome position: 28.48

GC content: 29.37

Gene sequence:

>1008_bases
TTGAATTTTAAAAAACTTCCTAAAATAGAGTTACATTGCCATTTAGATGGTTCATTGAGAGTAGACACAATATTAGATAT
AGCTAAAAAAGATAATATCCCTCTTCCTAGCTATAATAAAAAGGAGCTTATAAATTATGTTTCCATAATGGATGACTGTA
ATTCCCTAGATGAATACTTAAATAAGTTTTTTATACCTAACAAAGTTATGCAAACAAAGGAAAATTTAAAAAGAATAGCA
TTTGAATTATTAGAAGATGTTGCAGCAGATAATGTAAAATATATAGAAGTAAGATTTGCCCCTCTTTTACATGTTGAAAA
AGGATTAAATATTGAAGAAATTATAGAAAGTGTACTGGAAGGGATTAAAGAAGCCGAAAAGCTTTATGATATAAAAGGTA
ATTTAATATTAGGTTGTATGAGAAATATGGATATTCCTTCAGCCTTTGAAGTTGTAAAAAAAGGATCCAAATTTATTGGA
AAAGGTGTTGTTGCTATAGACCTTTGCGCTGGTGAAGAACCCCATTTCCCAGGAAAATATATAGAAGTTTTAAAGCTAGC
CAAAGAATGTGGTTATAGAATAACTATACATGCTGGAGAAGCTGGCGTAGGCGAAAATGTTTTAGAAGCTATCACTCTTT
TAAATGCTGAAAGAATAGGACATGGAATATATATTAAAAATTGTGCTGAAGCTTATAAACTTGTAAAAGAAAAAAATATT
CCACTGGAAGTGTGTCCAACAAGTAATCTTCATACTAAAGCTTTCGAAAGCTATGAAACCCATCCTTTTATGGATTTTCT
AAAAGATGGTATTAAGGTTACTATTAACACAGATAATATGACAGTATCTAATACTACCATAACAAAAGAACTAGAAATGC
TTAATAAGTTTTGTGGTTTATCTATAGAAGATTATAAAATACTATATCTAAATGCAGTAGAGGCATCTTTTGCATCTCCT
GAAACAAAAGAAATACTTAAATCATATGCTAATGAAATTACGGCTTAA

Upstream 100 bases:

>100_bases
TTACACAAATTAAATAATAAATTATAATTAAGTTTAACATTTTTAATAGATCTATATTATAAGAAATTACCTTAATCGGT
AATAGCAAGGAGTGACTAAT

Downstream 100 bases:

>100_bases
AAGCTTTTAAAGGTTAAGAATTAAAGCAAGAAATACTTTTAGTCAATAGATAGCTATAAAAATAAAGAATACTAATATTT
GTGTCTTAATATTTCAGCTA

Product: adenosine deaminase

Products: NA

Alternate protein names: Adenosine aminohydrolase [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MNFKKLPKIELHCHLDGSLRVDTILDIAKKDNIPLPSYNKKELINYVSIMDDCNSLDEYLNKFFIPNKVMQTKENLKRIA
FELLEDVAADNVKYIEVRFAPLLHVEKGLNIEEIIESVLEGIKEAEKLYDIKGNLILGCMRNMDIPSAFEVVKKGSKFIG
KGVVAIDLCAGEEPHFPGKYIEVLKLAKECGYRITIHAGEAGVGENVLEAITLLNAERIGHGIYIKNCAEAYKLVKEKNI
PLEVCPTSNLHTKAFESYETHPFMDFLKDGIKVTINTDNMTVSNTTITKELEMLNKFCGLSIEDYKILYLNAVEASFASP
ETKEILKSYANEITA

Sequences:

>Translated_335_residues
MNFKKLPKIELHCHLDGSLRVDTILDIAKKDNIPLPSYNKKELINYVSIMDDCNSLDEYLNKFFIPNKVMQTKENLKRIA
FELLEDVAADNVKYIEVRFAPLLHVEKGLNIEEIIESVLEGIKEAEKLYDIKGNLILGCMRNMDIPSAFEVVKKGSKFIG
KGVVAIDLCAGEEPHFPGKYIEVLKLAKECGYRITIHAGEAGVGENVLEAITLLNAERIGHGIYIKNCAEAYKLVKEKNI
PLEVCPTSNLHTKAFESYETHPFMDFLKDGIKVTINTDNMTVSNTTITKELEMLNKFCGLSIEDYKILYLNAVEASFASP
ETKEILKSYANEITA
>Mature_335_residues
MNFKKLPKIELHCHLDGSLRVDTILDIAKKDNIPLPSYNKKELINYVSIMDDCNSLDEYLNKFFIPNKVMQTKENLKRIA
FELLEDVAADNVKYIEVRFAPLLHVEKGLNIEEIIESVLEGIKEAEKLYDIKGNLILGCMRNMDIPSAFEVVKKGSKFIG
KGVVAIDLCAGEEPHFPGKYIEVLKLAKECGYRITIHAGEAGVGENVLEAITLLNAERIGHGIYIKNCAEAYKLVKEKNI
PLEVCPTSNLHTKAFESYETHPFMDFLKDGIKVTINTDNMTVSNTTITKELEMLNKFCGLSIEDYKILYLNAVEASFASP
ETKEILKSYANEITA

Specific function: Unknown

COG id: COG1816

COG function: function code F; Adenosine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenosine and AMP deaminases family [H]

Homologues:

Organism=Homo sapiens, GI47078295, Length=340, Percent_Identity=32.9411764705882, Blast_Score=174, Evalue=7e-44,
Organism=Homo sapiens, GI226693318, Length=341, Percent_Identity=24.9266862170088, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI61175224, Length=252, Percent_Identity=26.1904761904762, Blast_Score=80, Evalue=4e-15,
Organism=Escherichia coli, GI1787910, Length=326, Percent_Identity=32.8220858895706, Blast_Score=183, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI32565969, Length=334, Percent_Identity=30.2395209580838, Blast_Score=147, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI17538512, Length=334, Percent_Identity=30.2395209580838, Blast_Score=147, Evalue=6e-36,
Organism=Caenorhabditis elegans, GI115537133, Length=324, Percent_Identity=26.5432098765432, Blast_Score=89, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6324188, Length=336, Percent_Identity=24.4047619047619, Blast_Score=122, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24645260, Length=340, Percent_Identity=29.4117647058824, Blast_Score=106, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001365
- InterPro:   IPR006330 [H]

Pfam domain/function: PF00962 A_deaminase [H]

EC number: =3.5.4.4 [H]

Molecular weight: Translated: 37730; Mature: 37730

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFKKLPKIELHCHLDGSLRVDTILDIAKKDNIPLPSYNKKELINYVSIMDDCNSLDEYL
CCCCCCCCEEEEEEECCCEEHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
NKFFIPNKVMQTKENLKRIAFELLEDVAADNVKYIEVRFAPLLHVEKGLNIEEIIESVLE
HHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEHHHHHHHCCCCHHHHHHHHHH
GIKEAEKLYDIKGNLILGCMRNMDIPSAFEVVKKGSKFIGKGVVAIDLCAGEEPHFPGKY
HHHHHHHHHHCCCCEEEEEHHCCCCCHHHHHHHCCHHHHCCCEEEEEEECCCCCCCCHHH
IEVLKLAKECGYRITIHAGEAGVGENVLEAITLLNAERIGHGIYIKNCAEAYKLVKEKNI
HHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHCCC
PLEVCPTSNLHTKAFESYETHPFMDFLKDGIKVTINTDNMTVSNTTITKELEMLNKFCGL
CEEECCCCCCCHHHHHCCCCCHHHHHHHCCEEEEEECCCEEECCCHHHHHHHHHHHHHCC
SIEDYKILYLNAVEASFASPETKEILKSYANEITA
CCCCEEEEEEEEHHHHCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNFKKLPKIELHCHLDGSLRVDTILDIAKKDNIPLPSYNKKELINYVSIMDDCNSLDEYL
CCCCCCCCEEEEEEECCCEEHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
NKFFIPNKVMQTKENLKRIAFELLEDVAADNVKYIEVRFAPLLHVEKGLNIEEIIESVLE
HHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEHHHHHHHCCCCHHHHHHHHHH
GIKEAEKLYDIKGNLILGCMRNMDIPSAFEVVKKGSKFIGKGVVAIDLCAGEEPHFPGKY
HHHHHHHHHHCCCCEEEEEHHCCCCCHHHHHHHCCHHHHCCCEEEEEEECCCCCCCCHHH
IEVLKLAKECGYRITIHAGEAGVGENVLEAITLLNAERIGHGIYIKNCAEAYKLVKEKNI
HHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHCCC
PLEVCPTSNLHTKAFESYETHPFMDFLKDGIKVTINTDNMTVSNTTITKELEMLNKFCGL
CEEECCCCCCCHHHHHCCCCCHHHHHHHCCEEEEEECCCEEECCCHHHHHHHHHHHHHCC
SIEDYKILYLNAVEASFASPETKEILKSYANEITA
CCCCEEEEEEEEHHHHCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA