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The map label for this gene is cbiK [H]

Identifier: 226948226

GI number: 226948226

Start: 1143521

End: 1144303

Strand: Direct

Name: cbiK [H]

Synonym: CLM_1103

Alternate gene names: 226948226

Gene position: 1143521-1144303 (Clockwise)

Preceding gene: 226948225

Following gene: 226948227

Centisome position: 27.52

GC content: 26.82

Gene sequence:

>783_bases
ATGAATAAAAACAAAAGAGCTATATTAGTGGTGAGTTTTGGTACTAGTTATGAACAGTCATTAAAAGACTGTATAGAAAG
TACAGAAAATTTTATAAAAGAAAGTTTTAAAGATTATGATATAAAAAGAGCTTTTACTTCTTACATGATAATAAATAAAA
TATTAAAAAGAGATAATATAAAGATAAATAATCCTATAGAAGCATTAGAAGAACTTAAGAAGGAAGGCTATGAAGAAGTT
ATAGTTCAACCTCTACATATAATGTTTGGAGAAGAGTATGAAAAAATAGAAAAAGCTGTTATTAAGTTTAAAGATAAATT
TAAGGTATTAAAATTAGGAAAGCCTTTATTATTTAAAAATGAAGACTACAAAATAGCAACAGAAGCTTTAAAGACTCAAC
TTCCTAAATTAAATAAAGAGGAAGCTATAATACTTATGGGACATGGAACAGAACATCCAGCTAATGCTGCTTATTTTCAA
TTTGATTATTATTTAAGAGAACACATAAATCCTAATATATATCTTTGTAGTGTGGAAAGCGATCCTTCTATAAAATCAAT
AATACCAAAATTAAAGAAATCTGGAGTAAAAAATGTTTTACTAATGCCTTTTATGTTAGTGGCTGGAGATCATGCTAACA
ATGACATGGCAGGAGAGGATGAAGAATCCTGGAAAAATGTTTTGGAAAAGGAAGGCTTTAAAGTTGATTTATATTTAAAG
GGTCTAGGGGCAAATAGAGAATTTCAAAAAATATATAGAGATCATATAAAAGAAGAAATCTAA

Upstream 100 bases:

>100_bases
TAAAAAGTTTTATCAATTCAAATTAAGCAATATATTGAATGGATTTTTTAAGATAAATATTAATGTGATAATATCATTAG
ATTAGATCAGGAGGAGAAAC

Downstream 100 bases:

>100_bases
GGAGAGTATTTCATGGAAGTTAGAGCCAAATATCCAGGAAGTTTTGGAGAAATACTTCAAGGAAATTTAGTGGAAAAGCC
TATGTTGGTTTCTTCCCCTA

Product: anaerobic sirohydrochlorin cobaltochelatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MNKNKRAILVVSFGTSYEQSLKDCIESTENFIKESFKDYDIKRAFTSYMIINKILKRDNIKINNPIEALEELKKEGYEEV
IVQPLHIMFGEEYEKIEKAVIKFKDKFKVLKLGKPLLFKNEDYKIATEALKTQLPKLNKEEAIILMGHGTEHPANAAYFQ
FDYYLREHINPNIYLCSVESDPSIKSIIPKLKKSGVKNVLLMPFMLVAGDHANNDMAGEDEESWKNVLEKEGFKVDLYLK
GLGANREFQKIYRDHIKEEI

Sequences:

>Translated_260_residues
MNKNKRAILVVSFGTSYEQSLKDCIESTENFIKESFKDYDIKRAFTSYMIINKILKRDNIKINNPIEALEELKKEGYEEV
IVQPLHIMFGEEYEKIEKAVIKFKDKFKVLKLGKPLLFKNEDYKIATEALKTQLPKLNKEEAIILMGHGTEHPANAAYFQ
FDYYLREHINPNIYLCSVESDPSIKSIIPKLKKSGVKNVLLMPFMLVAGDHANNDMAGEDEESWKNVLEKEGFKVDLYLK
GLGANREFQKIYRDHIKEEI
>Mature_260_residues
MNKNKRAILVVSFGTSYEQSLKDCIESTENFIKESFKDYDIKRAFTSYMIINKILKRDNIKINNPIEALEELKKEGYEEV
IVQPLHIMFGEEYEKIEKAVIKFKDKFKVLKLGKPLLFKNEDYKIATEALKTQLPKLNKEEAIILMGHGTEHPANAAYFQ
FDYYLREHINPNIYLCSVESDPSIKSIIPKLKKSGVKNVLLMPFMLVAGDHANNDMAGEDEESWKNVLEKEGFKVDLYLK
GLGANREFQKIYRDHIKEEI

Specific function: Chelates cobalt to the cobalamin precursor as part of the anaerobic pathway to cobalamin biosynthesis [H]

COG id: COG4822

COG function: function code H; Cobalamin biosynthesis protein CbiK, Co2+ chelatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CbiK family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010388 [H]

Pfam domain/function: PF06180 CbiK [H]

EC number: =4.99.1.3 [H]

Molecular weight: Translated: 30207; Mature: 30207

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKNKRAILVVSFGTSYEQSLKDCIESTENFIKESFKDYDIKRAFTSYMIINKILKRDNI
CCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
KINNPIEALEELKKEGYEEVIVQPLHIMFGEEYEKIEKAVIKFKDKFKVLKLGKPLLFKN
CCCCHHHHHHHHHHCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCEEECC
EDYKIATEALKTQLPKLNKEEAIILMGHGTEHPANAAYFQFDYYLREHINPNIYLCSVES
CCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCEEEEHHHHHHHHCCCCEEEEEECC
DPSIKSIIPKLKKSGVKNVLLMPFMLVAGDHANNDMAGEDEESWKNVLEKEGFKVDLYLK
CCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEEE
GLGANREFQKIYRDHIKEEI
CCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNKNKRAILVVSFGTSYEQSLKDCIESTENFIKESFKDYDIKRAFTSYMIINKILKRDNI
CCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
KINNPIEALEELKKEGYEEVIVQPLHIMFGEEYEKIEKAVIKFKDKFKVLKLGKPLLFKN
CCCCHHHHHHHHHHCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCEEECC
EDYKIATEALKTQLPKLNKEEAIILMGHGTEHPANAAYFQFDYYLREHINPNIYLCSVES
CCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCEEEEHHHHHHHHCCCCEEEEEECC
DPSIKSIIPKLKKSGVKNVLLMPFMLVAGDHANNDMAGEDEESWKNVLEKEGFKVDLYLK
CCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEEE
GLGANREFQKIYRDHIKEEI
CCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8501034; 11677609; 9150215; 10451360 [H]