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The map label for this gene is cobU [H]

Identifier: 226948182

GI number: 226948182

Start: 1107692

End: 1108249

Strand: Direct

Name: cobU [H]

Synonym: CLM_1056

Alternate gene names: 226948182

Gene position: 1107692-1108249 (Clockwise)

Preceding gene: 226948181

Following gene: 226948183

Centisome position: 26.66

GC content: 26.16

Gene sequence:

>558_bases
ATGAGTGATAAAAATAAAGTTGTATTAATAACTGGTGGTGTAAGAAGTGGTAAAAGTGAATTTGCAGAAGGCCTACTTCA
AAATGAGAAAAGTGTTTTATACATAGCTACAGCAAAAATTACAGATAAGGAAATGGAACATAGAGTAGAAAAGCATAAGG
AAAGAAGAAATAGTACATGGAAAACCTATGAAGGATATAAAGATTTAGGAAAAATAATAAAATATTATGATGAGAAAAGT
ATTCTATTAGATTGTGTAACTGTAATGACAACAAACCTAATGTTTCATAAAGAAATAGATTATGAAAATATTAAAGAGGG
AGAATTAGATGAAATTTTAGAGGGGATAAAAAAAGAATTTTATAATCTAATAATATCAGTAAAAGAAGAAAATAAAAACA
TAATATTAGTTACTAATGAAGTAGGTTATAGCATTGTTCCAGCTTATAAATTAGGTAGGATATTTAGAGACTTTCAAGGT
ATTATAAATAAATTTATAGCTTCTTTGAGTGATGAGGTTTATTTAGTAACCTGTGGAATACCCTTAAAAATAAGATAG

Upstream 100 bases:

>100_bases
TAATTGATAAATATAATATAATCAATAGTTTCTCAAATAAGGTAAAAATTTTAAAAGCGTTAAAATACTTTTTATATAGT
ATTAGAATGGAGAATTAAAT

Downstream 100 bases:

>100_bases
TAACATTCCTCTTGATTTTGATATGGAAGAAATATTGTAGATAACTTAATTTTTAAAGTCAAAAAGGTCTATAAAACCTT
AGATTTATCAGAAAGATTAA

Product: adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MSDKNKVVLITGGVRSGKSEFAEGLLQNEKSVLYIATAKITDKEMEHRVEKHKERRNSTWKTYEGYKDLGKIIKYYDEKS
ILLDCVTVMTTNLMFHKEIDYENIKEGELDEILEGIKKEFYNLIISVKEENKNIILVTNEVGYSIVPAYKLGRIFRDFQG
IINKFIASLSDEVYLVTCGIPLKIR

Sequences:

>Translated_185_residues
MSDKNKVVLITGGVRSGKSEFAEGLLQNEKSVLYIATAKITDKEMEHRVEKHKERRNSTWKTYEGYKDLGKIIKYYDEKS
ILLDCVTVMTTNLMFHKEIDYENIKEGELDEILEGIKKEFYNLIISVKEENKNIILVTNEVGYSIVPAYKLGRIFRDFQG
IINKFIASLSDEVYLVTCGIPLKIR
>Mature_184_residues
SDKNKVVLITGGVRSGKSEFAEGLLQNEKSVLYIATAKITDKEMEHRVEKHKERRNSTWKTYEGYKDLGKIIKYYDEKSI
LLDCVTVMTTNLMFHKEIDYENIKEGELDEILEGIKKEFYNLIISVKEENKNIILVTNEVGYSIVPAYKLGRIFRDFQGI
INKFIASLSDEVYLVTCGIPLKIR

Specific function: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=184, Percent_Identity=40.2173913043478, Blast_Score=142, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 21382; Mature: 21251

Theoretical pI: Translated: 7.49; Mature: 7.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDKNKVVLITGGVRSGKSEFAEGLLQNEKSVLYIATAKITDKEMEHRVEKHKERRNSTW
CCCCCEEEEEECCCCCCHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHCCCCC
KTYEGYKDLGKIIKYYDEKSILLDCVTVMTTNLMFHKEIDYENIKEGELDEILEGIKKEF
CHHHCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHEEECCCCCCCCCCCHHHHHHHHHHHH
YNLIISVKEENKNIILVTNEVGYSIVPAYKLGRIFRDFQGIINKFIASLSDEVYLVTCGI
HHHEEEEEECCCCEEEEECCCCCEEECHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECC
PLKIR
EEEEC
>Mature Secondary Structure 
SDKNKVVLITGGVRSGKSEFAEGLLQNEKSVLYIATAKITDKEMEHRVEKHKERRNSTW
CCCCEEEEEECCCCCCHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHCCCCC
KTYEGYKDLGKIIKYYDEKSILLDCVTVMTTNLMFHKEIDYENIKEGELDEILEGIKKEF
CHHHCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHEEECCCCCCCCCCCHHHHHHHHHHHH
YNLIISVKEENKNIILVTNEVGYSIVPAYKLGRIFRDFQGIINKFIASLSDEVYLVTCGI
HHHEEEEEECCCCEEEEECCCCCEEECHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECC
PLKIR
EEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8501034; 11677609; 9601028; 10529169 [H]