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The map label for this gene is catB2 [H]

Identifier: 226948156

GI number: 226948156

Start: 1081823

End: 1082473

Strand: Direct

Name: catB2 [H]

Synonym: CLM_1026

Alternate gene names: 226948156

Gene position: 1081823-1082473 (Clockwise)

Preceding gene: 226948155

Following gene: 226948157

Centisome position: 26.03

GC content: 28.73

Gene sequence:

>651_bases
ATGAATAATACATTTAATCATTGGACAGAAATAAAATATTTAAAGGACTCAATAAAAAATCCTTTAATTGAAGTAGGAGA
ATACACATATTATTCAGGATATTATGCAGGTGGAGATTTTGAAGATGTTTGTGTGCGATATATATGGGGAGACGAAAAAT
CAAAAGAAATGTACAATCCTATAGAAGACTATGGATGGACTTTAGATAAAATAAAAATAGGTAAATATTGTTGTTTTGCT
AGCGGAGTAGCATTTATGATGGGAGGAAATCACAATCATAATCCTAATTGGATAACTGTATATCCATTTAAAAATAAGTT
GCTAGATTCATATAAGCCTAAAGGAGATACAATTGTAGGTAATGACGTATGGATTGGTACAGAAGCAATGATTATGCCAG
GAATTACAATTGGGGATGGGGCAATAATCGGAGTTAGGTCAATAGTTACAAAAAATGTAGAACCTTATACTGTTGTAGCA
GGAAATCCAGCAAAACATATAAAAGAAAGATTTGATAAAGAAAAGATAGATATGTTACTTAAAATAAAATGGTGGGATTG
GGAAGAAGATCATATTAAAAAATGTATAGATATATTGTCTAGTTCAGATATAGATGAATTATATAAATATTATGAAATGA
ATATAAAATAA

Upstream 100 bases:

>100_bases
ATTAGAATGGCAAAGAGAATCAAAAAATTTAGGAATGTAGCAGTGTGAACTAAGTTAAGGGATATTTAAAAGTAAAAACT
TAGAAACTTAGGAGGACAAG

Downstream 100 bases:

>100_bases
TCTATTATTTACTTTATTAAAGCATAATATAAGAATATAATTATAAAACAATAAATAATAAAAAAATTTAATTAAGAATA
AAGCACTAATCTTTTAAAGA

Product: chloramphenicol acetyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MNNTFNHWTEIKYLKDSIKNPLIEVGEYTYYSGYYAGGDFEDVCVRYIWGDEKSKEMYNPIEDYGWTLDKIKIGKYCCFA
SGVAFMMGGNHNHNPNWITVYPFKNKLLDSYKPKGDTIVGNDVWIGTEAMIMPGITIGDGAIIGVRSIVTKNVEPYTVVA
GNPAKHIKERFDKEKIDMLLKIKWWDWEEDHIKKCIDILSSSDIDELYKYYEMNIK

Sequences:

>Translated_216_residues
MNNTFNHWTEIKYLKDSIKNPLIEVGEYTYYSGYYAGGDFEDVCVRYIWGDEKSKEMYNPIEDYGWTLDKIKIGKYCCFA
SGVAFMMGGNHNHNPNWITVYPFKNKLLDSYKPKGDTIVGNDVWIGTEAMIMPGITIGDGAIIGVRSIVTKNVEPYTVVA
GNPAKHIKERFDKEKIDMLLKIKWWDWEEDHIKKCIDILSSSDIDELYKYYEMNIK
>Mature_216_residues
MNNTFNHWTEIKYLKDSIKNPLIEVGEYTYYSGYYAGGDFEDVCVRYIWGDEKSKEMYNPIEDYGWTLDKIKIGKYCCFA
SGVAFMMGGNHNHNPNWITVYPFKNKLLDSYKPKGDTIVGNDVWIGTEAMIMPGITIGDGAIIGVRSIVTKNVEPYTVVA
GNPAKHIKERFDKEKIDMLLKIKWWDWEEDHIKKCIDILSSSDIDELYKYYEMNIK

Specific function: This enzyme is an effector of chloramphenicol resistance in bacteria [H]

COG id: COG0110

COG function: function code R; Acetyltransferase (isoleucine patch superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1786537, Length=57, Percent_Identity=50.8771929824561, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788367, Length=122, Percent_Identity=31.1475409836066, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1786664, Length=100, Percent_Identity=36, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR018357
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00132 Hexapep [H]

EC number: =2.3.1.28 [H]

Molecular weight: Translated: 25077; Mature: 25077

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNTFNHWTEIKYLKDSIKNPLIEVGEYTYYSGYYAGGDFEDVCVRYIWGDEKSKEMYNP
CCCCCCHHHHHHHHHHHHCCCCEECCCEEEECCEECCCCHHHHHEEEEECCCCCHHHCCC
IEDYGWTLDKIKIGKYCCFASGVAFMMGGNHNHNPNWITVYPFKNKLLDSYKPKGDTIVG
HHHHCCEEEEEECCCCHHHHCCEEEEECCCCCCCCCEEEEECCHHHHHHCCCCCCCEEEC
NDVWIGTEAMIMPGITIGDGAIIGVRSIVTKNVEPYTVVAGNPAKHIKERFDKEKIDMLL
CCEEECCCCEEECCEEECCCCEEHHHHHHHCCCCCEEEEECCHHHHHHHHHCHHHCCEEE
KIKWWDWEEDHIKKCIDILSSSDIDELYKYYEMNIK
EEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MNNTFNHWTEIKYLKDSIKNPLIEVGEYTYYSGYYAGGDFEDVCVRYIWGDEKSKEMYNP
CCCCCCHHHHHHHHHHHHCCCCEECCCEEEECCEECCCCHHHHHEEEEECCCCCHHHCCC
IEDYGWTLDKIKIGKYCCFASGVAFMMGGNHNHNPNWITVYPFKNKLLDSYKPKGDTIVG
HHHHCCEEEEEECCCCHHHHCCEEEEECCCCCCCCCEEEEECCHHHHHHCCCCCCCEEEC
NDVWIGTEAMIMPGITIGDGAIIGVRSIVTKNVEPYTVVAGNPAKHIKERFDKEKIDMLL
CCEEECCCCEEECCEEECCCCEEHHHHHHHCCCCCEEEEECCHHHHHHHHHCHHHCCEEE
KIKWWDWEEDHIKKCIDILSSSDIDELYKYYEMNIK
EEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1314803 [H]