Click here to switch to the map view.

The map label for this gene is ycbM [H]

Identifier: 226948069

GI number: 226948069

Start: 988371

End: 989276

Strand: Direct

Name: ycbM [H]

Synonym: CLM_0930

Alternate gene names: 226948069

Gene position: 988371-989276 (Clockwise)

Preceding gene: 226948068

Following gene: 226948070

Centisome position: 23.79

GC content: 24.17

Gene sequence:

>906_bases
ATGATTTTTATTATAATAGTGCTAATAATTTTTTTGCTCTTTTTACTCTCCTATGTATTTTTTATGAAAAGAGAAATAAA
AAATATTACAATCCAATTAAATGAATATAATAATTTGGAATCATTAAAAAAGATAGATGCTACTCTTTTTGATAAAGAAA
TTGAAAATTTAGCTTATAGCATTAATAAACATATCGATATAAATATACAATCACAAATTAAGCAAAAGAGACTAGAGGAA
GAAATAAGAAAAAATATAGCTAATGTATCCCATGATTTGCGCACCCCCCTTACATCTATTATAGGTTATATACAAATGAT
AAAAAAAGGGAATCTATCGAAGGAAAAGCAAATGGAATATATAGATATAGCTGAAAAAAGAGCAAAGGATTTACAAAATT
TATTAAGTGATTTTTTTGAACTTTCCATTATAGAATTACCAGATTATTATATTGAGCTTCAAAAGATTAATATAAATAAT
ATACTGTGTGAAGTAATAGCTTCTTTTTATAGTAGTTTTGTAGATAAAAATATAACTCCTAAAATAGATTTGCCAAAGGA
GAATATTATGGTCATTGGGAATGAAGGGGCTATAAAGAGGATACTACAAAATTTAATAGTAAATATGATAAAACATTCTA
AAGAGGATGTTTATATAAGCTTAAAAAAAGAAAATGATAAAGCTGTATTAACTGCAATTAACAAATGCGATAATATTACA
GAGGGAGACATAGAGCTAATTTTTAATAGATTTTATAAAAAAGATAATGCCAGAACTAATAAAAATGGAAGCACTGGATT
AGGTTTATTTATTTCTAAAAGTCTTATGGAAAAAATGAATGGAGAAATTTATGCTGAAGTTCATGAAAATTTATTACATA
TTTTTTGTAAATGGAATTTGAAGTAA

Upstream 100 bases:

>100_bases
TCTCGGTACTAAAGTACTGAGTATTCTGTGTTGTTTGATAAATAAATTAAAAAGATTATAAGTTAAGAAAAGATTATTTA
AAAAGGGGAGGGGGAGTAAC

Downstream 100 bases:

>100_bases
TTTTAAATTCGATAGATGTGTTTTGATATGTTGCTAATTATTATAAAAGCAATAATATGAATAGATTATAAAAGAATACA
TTTTACTTCAATCTAAAAAT

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MIFIIIVLIIFLLFLLSYVFFMKREIKNITIQLNEYNNLESLKKIDATLFDKEIENLAYSINKHIDINIQSQIKQKRLEE
EIRKNIANVSHDLRTPLTSIIGYIQMIKKGNLSKEKQMEYIDIAEKRAKDLQNLLSDFFELSIIELPDYYIELQKININN
ILCEVIASFYSSFVDKNITPKIDLPKENIMVIGNEGAIKRILQNLIVNMIKHSKEDVYISLKKENDKAVLTAINKCDNIT
EGDIELIFNRFYKKDNARTNKNGSTGLGLFISKSLMEKMNGEIYAEVHENLLHIFCKWNLK

Sequences:

>Translated_301_residues
MIFIIIVLIIFLLFLLSYVFFMKREIKNITIQLNEYNNLESLKKIDATLFDKEIENLAYSINKHIDINIQSQIKQKRLEE
EIRKNIANVSHDLRTPLTSIIGYIQMIKKGNLSKEKQMEYIDIAEKRAKDLQNLLSDFFELSIIELPDYYIELQKININN
ILCEVIASFYSSFVDKNITPKIDLPKENIMVIGNEGAIKRILQNLIVNMIKHSKEDVYISLKKENDKAVLTAINKCDNIT
EGDIELIFNRFYKKDNARTNKNGSTGLGLFISKSLMEKMNGEIYAEVHENLLHIFCKWNLK
>Mature_301_residues
MIFIIIVLIIFLLFLLSYVFFMKREIKNITIQLNEYNNLESLKKIDATLFDKEIENLAYSINKHIDINIQSQIKQKRLEE
EIRKNIANVSHDLRTPLTSIIGYIQMIKKGNLSKEKQMEYIDIAEKRAKDLQNLLSDFFELSIIELPDYYIELQKININN
ILCEVIASFYSSFVDKNITPKIDLPKENIMVIGNEGAIKRILQNLIVNMIKHSKEDVYISLKKENDKAVLTAINKCDNIT
EGDIELIFNRFYKKDNARTNKNGSTGLGLFISKSLMEKMNGEIYAEVHENLLHIFCKWNLK

Specific function: Member of the two-component regulatory system ycbM/ycbL. Probably activates ycbL by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=231, Percent_Identity=26.8398268398268, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1790346, Length=266, Percent_Identity=25.5639097744361, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1789149, Length=283, Percent_Identity=26.5017667844523, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1786600, Length=232, Percent_Identity=24.5689655172414, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788393, Length=211, Percent_Identity=26.0663507109005, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI48994928, Length=205, Percent_Identity=25.3658536585366, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI87082128, Length=285, Percent_Identity=21.4035087719298, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 35119; Mature: 35119

Theoretical pI: Translated: 8.04; Mature: 8.04

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFIIIVLIIFLLFLLSYVFFMKREIKNITIQLNEYNNLESLKKIDATLFDKEIENLAYS
CHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
INKHIDINIQSQIKQKRLEEEIRKNIANVSHDLRTPLTSIIGYIQMIKKGNLSKEKQMEY
HCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
IDIAEKRAKDLQNLLSDFFELSIIELPDYYIELQKININNILCEVIASFYSSFVDKNITP
HHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCC
KIDLPKENIMVIGNEGAIKRILQNLIVNMIKHSKEDVYISLKKENDKAVLTAINKCDNIT
CCCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCCC
EGDIELIFNRFYKKDNARTNKNGSTGLGLFISKSLMEKMNGEIYAEVHENLLHIFCKWNL
CCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCC
K
C
>Mature Secondary Structure
MIFIIIVLIIFLLFLLSYVFFMKREIKNITIQLNEYNNLESLKKIDATLFDKEIENLAYS
CHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
INKHIDINIQSQIKQKRLEEEIRKNIANVSHDLRTPLTSIIGYIQMIKKGNLSKEKQMEY
HCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
IDIAEKRAKDLQNLLSDFFELSIIELPDYYIELQKININNILCEVIASFYSSFVDKNITP
HHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCC
KIDLPKENIMVIGNEGAIKRILQNLIVNMIKHSKEDVYISLKKENDKAVLTAINKCDNIT
CCCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCCC
EGDIELIFNRFYKKDNARTNKNGSTGLGLFISKSLMEKMNGEIYAEVHENLLHIFCKWNL
CCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]