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The map label for this gene is ycbL [H]

Identifier: 226947966

GI number: 226947966

Start: 887149

End: 887847

Strand: Direct

Name: ycbL [H]

Synonym: CLM_0825

Alternate gene names: 226947966

Gene position: 887149-887847 (Clockwise)

Preceding gene: 226947965

Following gene: 226947967

Centisome position: 21.35

GC content: 36.19

Gene sequence:

>699_bases
TTGAAACATATTTTCTTTGTTGAAGATGATTTGAGTTTAATTAATGGGTTATCTTTTGCTATCAAAAAACAAGGATATGA
AATAGATGTTGCCCGTACAAGTCTTGAAGCAGAAGCACTATGGAAAAATGGGAAATATGATTTGGTGATTTTGGACGTAT
CGCTTCCTGATGGCTCCGGCTATGATTTATGCAAAAAAATTCGTAAAACATCAAAGGTGCCGATTATGTTTCTTACTGCT
GCTGATGAAGAAACGGATATCATAATGGGGCTTGATATTGGTGGTGACGATTACATAACAAAGCCGTTCAAACTGGCGGT
GTTTATGTCGAGAATAAATGCTTTGCTTCGCAGAAGTAACAATTTTAATCAAGCTGATACCGAATTGAATTCTAATGGTA
TAAACGTACAACTGCTAAAAGGAGAAGTCTATAAAAATGGAGAACAACTTGACTTAACAGCAAGTGAGTATAAATTGTTA
TGCATGTTTATGGAAAATCCGGATATTGTTCTTTCTCCGGAACAGATTTTAAGCAGACTATGGGATTGCAACGAAAACTA
TATAGATAATAATACTCTTACCGTATATATACGCAGACTGCGTACAAAAATCGAAGATAATCCGGGAGAGCCTCAAAAAA
TAGTGACTGTTCGGCGTATGGGGTATAAATGGAGTACTGTTGATTGGGGTGTACGATGA

Upstream 100 bases:

>100_bases
GTGTTGTCCGTTTCAGCCGTATGTGGCTTATTCCCAAAGACGCGGAGAAGCCCGCTGACGGACGACATACACGCAGAAAA
ATGAAGGACGGTGAAAACAA

Downstream 100 bases:

>100_bases
AAATATTGGCAAACAGGAAAATCAAAAAACTTTTCCGTTTGGTATTGCTGTTTATAGTAGCATTCACCTTGATTTCTGCT
GTTTTCATAGTTTTGAAATT

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MKHIFFVEDDLSLINGLSFAIKKQGYEIDVARTSLEAEALWKNGKYDLVILDVSLPDGSGYDLCKKIRKTSKVPIMFLTA
ADEETDIIMGLDIGGDDYITKPFKLAVFMSRINALLRRSNNFNQADTELNSNGINVQLLKGEVYKNGEQLDLTASEYKLL
CMFMENPDIVLSPEQILSRLWDCNENYIDNNTLTVYIRRLRTKIEDNPGEPQKIVTVRRMGYKWSTVDWGVR

Sequences:

>Translated_232_residues
MKHIFFVEDDLSLINGLSFAIKKQGYEIDVARTSLEAEALWKNGKYDLVILDVSLPDGSGYDLCKKIRKTSKVPIMFLTA
ADEETDIIMGLDIGGDDYITKPFKLAVFMSRINALLRRSNNFNQADTELNSNGINVQLLKGEVYKNGEQLDLTASEYKLL
CMFMENPDIVLSPEQILSRLWDCNENYIDNNTLTVYIRRLRTKIEDNPGEPQKIVTVRRMGYKWSTVDWGVR
>Mature_232_residues
MKHIFFVEDDLSLINGLSFAIKKQGYEIDVARTSLEAEALWKNGKYDLVILDVSLPDGSGYDLCKKIRKTSKVPIMFLTA
ADEETDIIMGLDIGGDDYITKPFKLAVFMSRINALLRRSNNFNQADTELNSNGINVQLLKGEVYKNGEQLDLTASEYKLL
CMFMENPDIVLSPEQILSRLWDCNENYIDNNTLTVYIRRLRTKIEDNPGEPQKIVTVRRMGYKWSTVDWGVR

Specific function: Member of the two-component regulatory system ycbM/ycbL [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790552, Length=220, Percent_Identity=39.0909090909091, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=31.25, Blast_Score=133, Evalue=8e-33,
Organism=Escherichia coli, GI1786784, Length=226, Percent_Identity=34.9557522123894, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1786599, Length=228, Percent_Identity=33.7719298245614, Blast_Score=131, Evalue=3e-32,
Organism=Escherichia coli, GI1790863, Length=232, Percent_Identity=34.9137931034483, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=30.8370044052863, Blast_Score=117, Evalue=5e-28,
Organism=Escherichia coli, GI1790860, Length=221, Percent_Identity=30.316742081448, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI87082012, Length=224, Percent_Identity=30.3571428571429, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1787229, Length=208, Percent_Identity=32.6923076923077, Blast_Score=114, Evalue=4e-27,
Organism=Escherichia coli, GI1788394, Length=224, Percent_Identity=30.3571428571429, Blast_Score=114, Evalue=4e-27,
Organism=Escherichia coli, GI1789402, Length=220, Percent_Identity=32.2727272727273, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=32.1266968325792, Blast_Score=103, Evalue=8e-24,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=31.0043668122271, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI145693140, Length=239, Percent_Identity=26.3598326359833, Blast_Score=80, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26560; Mature: 26560

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHIFFVEDDLSLINGLSFAIKKQGYEIDVARTSLEAEALWKNGKYDLVILDVSLPDGSG
CCEEEEEECCHHHHCCCEEEEECCCCEEEEEECCCCHHHHHCCCCEEEEEEEEECCCCCC
YDLCKKIRKTSKVPIMFLTAADEETDIIMGLDIGGDDYITKPFKLAVFMSRINALLRRSN
HHHHHHHHHCCCCCEEEEEECCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCC
NFNQADTELNSNGINVQLLKGEVYKNGEQLDLTASEYKLLCMFMENPDIVLSPEQILSRL
CCCCCCCEECCCCCEEEEEECHHHCCCCEEEEECCCEEEEEEEECCCCEEECHHHHHHHH
WDCNENYIDNNTLTVYIRRLRTKIEDNPGEPQKIVTVRRMGYKWSTVDWGVR
HCCCCCEECCCCCEEHEEHHHHHHCCCCCCCHHEEEEECCCCEECCCCCCCC
>Mature Secondary Structure
MKHIFFVEDDLSLINGLSFAIKKQGYEIDVARTSLEAEALWKNGKYDLVILDVSLPDGSG
CCEEEEEECCHHHHCCCEEEEECCCCEEEEEECCCCHHHHHCCCCEEEEEEEEECCCCCC
YDLCKKIRKTSKVPIMFLTAADEETDIIMGLDIGGDDYITKPFKLAVFMSRINALLRRSN
HHHHHHHHHCCCCCEEEEEECCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCC
NFNQADTELNSNGINVQLLKGEVYKNGEQLDLTASEYKLLCMFMENPDIVLSPEQILSRL
CCCCCCCEECCCCCEEEEEECHHHCCCCEEEEECCCEEEEEEEECCCCEEECHHHHHHHH
WDCNENYIDNNTLTVYIRRLRTKIEDNPGEPQKIVTVRRMGYKWSTVDWGVR
HCCCCCEECCCCCEEHEEHHHHHHCCCCCCCHHEEEEECCCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]