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The map label for this gene is blaI [H]

Identifier: 226947941

GI number: 226947941

Start: 861099

End: 861473

Strand: Direct

Name: blaI [H]

Synonym: CLM_0799

Alternate gene names: 226947941

Gene position: 861099-861473 (Clockwise)

Preceding gene: 226947940

Following gene: 226947942

Centisome position: 20.72

GC content: 24.8

Gene sequence:

>375_bases
ATGGGAGACATACCTAAAATTTCTGAAACTGAGTGGAAAGTTATGAAAATAATATGGTCTAATCCATATATAACAGCTAA
TGAAGTAATTGATATATTAGATGATTATGTTGAATGGAAACCTAAAACTGTAAAAACTCTATTAAATAGACTTTTAAATA
AAGGAGCTATACATTTCGAAAAGGAAGGTAGAGAATATAAATATTATCCACTAGTAAGTGAAGATGAATGTATAAGAGAA
GAAAATAAATCATTTTTAGATAAGGTTTATAATGGTGCATTTAAAACTATGATAGCTAATTTTATAGAAGAACAAAATTT
GACTAAGGAAGATATAGACGATTTAAAAAAATTATTAGAAAAGAATAATAAGTAG

Upstream 100 bases:

>100_bases
AGATACATTCAAAAAATAATTGGCAGTATCTTTGTCTATTATTTTTTAAAAATATAGATTATAATTTATTAGAGAATAAC
TTTAGACAGGAGGAGAATGC

Downstream 100 bases:

>100_bases
GGAATATCTTATGAAAGCTTATAATTTTTTATCATACATGTCTTATTCTACTATTTCCATAACTTTAGTTATTATTGCTT
TAATATTAATTAGAGGAATA

Product: penicillinase repressor

Products: NA

Alternate protein names: Beta-lactamase repressor protein; Regulatory protein BlaI [H]

Number of amino acids: Translated: 124; Mature: 123

Protein sequence:

>124_residues
MGDIPKISETEWKVMKIIWSNPYITANEVIDILDDYVEWKPKTVKTLLNRLLNKGAIHFEKEGREYKYYPLVSEDECIRE
ENKSFLDKVYNGAFKTMIANFIEEQNLTKEDIDDLKKLLEKNNK

Sequences:

>Translated_124_residues
MGDIPKISETEWKVMKIIWSNPYITANEVIDILDDYVEWKPKTVKTLLNRLLNKGAIHFEKEGREYKYYPLVSEDECIRE
ENKSFLDKVYNGAFKTMIANFIEEQNLTKEDIDDLKKLLEKNNK
>Mature_123_residues
GDIPKISETEWKVMKIIWSNPYITANEVIDILDDYVEWKPKTVKTLLNRLLNKGAIHFEKEGREYKYYPLVSEDECIREE
NKSFLDKVYNGAFKTMIANFIEEQNLTKEDIDDLKKLLEKNNK

Specific function: Transcriptional repressor that constitutively blocks expression of beta-lactamase. Regulates genes involved in antibiotic resistance. Binds DNA as a dimer [H]

COG id: COG3682

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BlaI transcriptional regulatory family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005650
- InterPro:   IPR011991 [H]

Pfam domain/function: PF03965 Pencillinase_R [H]

EC number: NA

Molecular weight: Translated: 14721; Mature: 14590

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDIPKISETEWKVMKIIWSNPYITANEVIDILDDYVEWKPKTVKTLLNRLLNKGAIHFE
CCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEC
KEGREYKYYPLVSEDECIREENKSFLDKVYNGAFKTMIANFIEEQNLTKEDIDDLKKLLE
CCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
KNNK
HCCC
>Mature Secondary Structure 
GDIPKISETEWKVMKIIWSNPYITANEVIDILDDYVEWKPKTVKTLLNRLLNKGAIHFE
CCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEC
KEGREYKYYPLVSEDECIREENKSFLDKVYNGAFKTMIANFIEEQNLTKEDIDDLKKLLE
CCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
KNNK
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3096969; 3305074; 3260234; 3040663; 3498148 [H]