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The map label for this gene is penPC [H]

Identifier: 226947940

GI number: 226947940

Start: 859967

End: 860893

Strand: Direct

Name: penPC [H]

Synonym: CLM_0798

Alternate gene names: 226947940

Gene position: 859967-860893 (Clockwise)

Preceding gene: 226947939

Following gene: 226947941

Centisome position: 20.7

GC content: 29.77

Gene sequence:

>927_bases
ATGAAAAAAATAGTAAACTCAAAATTAAAGGTAAATAAATTTAAAATGTGTATATTTATATCAATTCTTATATTTTCTCT
TACTGGATGTGGAAATGTAGAAAATAAAACTTCTGAAAATACAAAACCTGAGATACAATATAATTCAGCATTTTCAAAAA
TTGAAAGTGATTATGGTGTTAAACTTGGTGTATATGCTTTTGATACAGAAACAAATAAAGAAGTTACATATAATGCTGAT
AAGAGATTCGCTTACTGTTCTACCTTTAAATCTTTAATATCCGGTGCGATTTTACAAAAATATTCATCAGACCAACTTAA
ACAAGTAATTAAATATAGCCCAAAAGATGTACTGTCTTATGCACCAGTTACAAAAAATCATGTTGATAAAGGTATGACTA
TTGAAGAACTTTGCGATGCGGCAGTACGCTTTAGTGATAATACAGCTGCAAATCTTTTGATTAATCTTATAGGTGGACCT
AATGGTTTTAAATCAGCACTTAATCAATTAGGTGACACAGTTACAGAACCTGCACGTATCGAACCAGAACTAAATGTTGC
TACACCTGGAGATAATAGGGATACTAGTACTCCAAGACAATTATCAATTGATTTAAAAGAATACACAACTGGAAATATAT
TATCAGATGATAAGAAAAAAATTCTTATTAATTGGATGTCAGGAAATGCAACAGGTGATAAGCTAATTCGTGCAGGAGCA
CCAAAAGACTGGATGGTTTCTGATAAAAGTGGAACTGGTTCTTACGGAACAAGAAATGATATTGCAATAGTAATACCACC
AAATAAAAAGCCTATATTTATTGCAATATTATCAAGTAAAAACGATAAAGATGCTAAATATGATGACAAAACAATTTCTG
AGGCTTCTAAAATTGTATTTGATTATTTTATTAACACCAGGAAATAG

Upstream 100 bases:

>100_bases
TCTCTATGAATAGGAATTGTTCCTAAGAAATTAGGTGATAAATTTGTTTTTGTTATAAAATAACTTAGCAAACAGATTAA
GAAATAAAAGGAGAATTTAG

Downstream 100 bases:

>100_bases
CAACTAAAATATAACTATCAAAAATCTTTAATAAGACACTAATCCACTTGATAGAGTGTATTTTCATCAAGTGAATTTTT
GTACCCATCTAGGAAGTCCT

Product: beta-lactamase

Products: NA

Alternate protein names: Beta-lactamase I; Penicillinase [H]

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MKKIVNSKLKVNKFKMCIFISILIFSLTGCGNVENKTSENTKPEIQYNSAFSKIESDYGVKLGVYAFDTETNKEVTYNAD
KRFAYCSTFKSLISGAILQKYSSDQLKQVIKYSPKDVLSYAPVTKNHVDKGMTIEELCDAAVRFSDNTAANLLINLIGGP
NGFKSALNQLGDTVTEPARIEPELNVATPGDNRDTSTPRQLSIDLKEYTTGNILSDDKKKILINWMSGNATGDKLIRAGA
PKDWMVSDKSGTGSYGTRNDIAIVIPPNKKPIFIAILSSKNDKDAKYDDKTISEASKIVFDYFINTRK

Sequences:

>Translated_308_residues
MKKIVNSKLKVNKFKMCIFISILIFSLTGCGNVENKTSENTKPEIQYNSAFSKIESDYGVKLGVYAFDTETNKEVTYNAD
KRFAYCSTFKSLISGAILQKYSSDQLKQVIKYSPKDVLSYAPVTKNHVDKGMTIEELCDAAVRFSDNTAANLLINLIGGP
NGFKSALNQLGDTVTEPARIEPELNVATPGDNRDTSTPRQLSIDLKEYTTGNILSDDKKKILINWMSGNATGDKLIRAGA
PKDWMVSDKSGTGSYGTRNDIAIVIPPNKKPIFIAILSSKNDKDAKYDDKTISEASKIVFDYFINTRK
>Mature_308_residues
MKKIVNSKLKVNKFKMCIFISILIFSLTGCGNVENKTSENTKPEIQYNSAFSKIESDYGVKLGVYAFDTETNKEVTYNAD
KRFAYCSTFKSLISGAILQKYSSDQLKQVIKYSPKDVLSYAPVTKNHVDKGMTIEELCDAAVRFSDNTAANLLINLIGGP
NGFKSALNQLGDTVTEPARIEPELNVATPGDNRDTSTPRQLSIDLKEYTTGNILSDDKKKILINWMSGNATGDKLIRAGA
PKDWMVSDKSGTGSYGTRNDIAIVIPPNKKPIFIAILSSKNDKDAKYDDKTISEASKIVFDYFINTRK

Specific function: Acts preferentially on penicillins [H]

COG id: COG2367

COG function: function code V; Beta-lactamase class A

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-A beta-lactamase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466
- InterPro:   IPR000871 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 34095; Mature: 34095

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00146 BETA_LACTAMASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIVNSKLKVNKFKMCIFISILIFSLTGCGNVENKTSENTKPEIQYNSAFSKIESDYGV
CCCHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECHHHHHHHHCCCC
KLGVYAFDTETNKEVTYNADKRFAYCSTFKSLISGAILQKYSSDQLKQVIKYSPKDVLSY
EEEEEEECCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHC
APVTKNHVDKGMTIEELCDAAVRFSDNTAANLLINLIGGPNGFKSALNQLGDTVTEPARI
CCCCHHHCCCCCCHHHHHHHHHCCCCCCHHEEEEEECCCCCHHHHHHHHHHHHHCCCCCC
EPELNVATPGDNRDTSTPRQLSIDLKEYTTGNILSDDKKKILINWMSGNATGDKLIRAGA
CCCEEEECCCCCCCCCCCCEEEEEHHHCCCCCCCCCCCCEEEEEEECCCCCHHHHEECCC
PKDWMVSDKSGTGSYGTRNDIAIVIPPNKKPIFIAILSSKNDKDAKYDDKTISEASKIVF
CCCCEEECCCCCCCCCCCCCEEEEECCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHH
DYFINTRK
HHHHCCCC
>Mature Secondary Structure
MKKIVNSKLKVNKFKMCIFISILIFSLTGCGNVENKTSENTKPEIQYNSAFSKIESDYGV
CCCHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECHHHHHHHHCCCC
KLGVYAFDTETNKEVTYNADKRFAYCSTFKSLISGAILQKYSSDQLKQVIKYSPKDVLSY
EEEEEEECCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHC
APVTKNHVDKGMTIEELCDAAVRFSDNTAANLLINLIGGPNGFKSALNQLGDTVTEPARI
CCCCHHHCCCCCCHHHHHHHHHCCCCCCHHEEEEEECCCCCHHHHHHHHHHHHHCCCCCC
EPELNVATPGDNRDTSTPRQLSIDLKEYTTGNILSDDKKKILINWMSGNATGDKLIRAGA
CCCEEEECCCCCCCCCCCCEEEEEHHHCCCCCCCCCCCCEEEEEEECCCCCHHHHEECCC
PKDWMVSDKSGTGSYGTRNDIAIVIPPNKKPIFIAILSSKNDKDAKYDDKTISEASKIVF
CCCCEEECCCCCCCCCCCCCEEEEECCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHH
DYFINTRK
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2991192 [H]