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The map label for this gene is gltS [H]

Identifier: 226947918

GI number: 226947918

Start: 835880

End: 837064

Strand: Direct

Name: gltS [H]

Synonym: CLM_0776

Alternate gene names: 226947918

Gene position: 835880-837064 (Clockwise)

Preceding gene: 226947916

Following gene: 226947920

Centisome position: 20.12

GC content: 32.57

Gene sequence:

>1185_bases
ATGACATTAGAGCTTGATATGATTCAAACCACTACCTTAGCTATATTTTTCTATTATATAGGTGTATTTATAAAATCTAA
AGTTTCAATTCTTGAAAAATTTTGTATACCTGCTCCAGTTGTAGGTGGACTTATTTTTGCTATTTTAAATTTAATCTTTA
CAGAAAGTGGTTTTATATCTATATCTTTAGACACAACTCTTCAAAAGCCTTTTATGTTAGCTTTCTTTACAACTATTGGC
CTTGGGGCAAGTTTTAAGATGATAAAACAGGGTGGTCTTCATGTGATAATGTTTTTTATAGCGGCTCTTCTTTTAGTAAT
ATCACAAGACTTTCTTGGAGTAGTTATGGCTAAATTTATAGGTGAAGATCCACTTCTTGGATTAATTGTTGGATCCGTAA
CCATGACTGGTGGTCATGGAACAGGAGCCACTTTTGGAGCCTTATTCGAATCAGAATACGGCCTTGTAGGCGCTTCCACT
ACAGCTATGGCTGCCGCTACCTTTGGGCTTGTATGTGGTAGCTTAATAGGTGGTCCGATAGCTAAAAACCTAATAAGTAA
AAATAACCTAAAAAATAACTCAGATGAGTTTTTTGAAACAAATTCTGATGATTGTGAAGAAGTGAGTTATAAAACGCTAT
TTAATACATTTTCTCTTATATTTATATCAATGGGACTCGGTTCTATTTTAGAGATGTTTTTTACAAACCTTGGTATAGTC
CTTCCTTCATACATAGACGCTATGATAGTGGCAGCTATAATACTTAATATAGGGGAACAAACAAATAAATGGAAAATAAA
TTCAAAATGTGCTGATATAATTGGAAGTATGAGCCTTAATGTGTTTTTATCCATGGCACTTATAAGTCTTAAATTATGGG
AATTAAAAAGCACAGCAGGTCCATTATTAATTTTATTAATAGGTCAAGCTGTATTAATGTTTATGTTTGCATACTTTATT
ACTTTTAGACTAATGGGAAAGGATTATGATGCTGCTGTTATGAGTTCTGGGCATTGTGGATTTGGAATGGGAGCTACTCC
TAACGGTATAGCAAACATGGAAGCCATAACTTCTAAATATGGTGCATCACCAAAAGCATTTTTTATTCTTCCAGTTGTCG
GGGCATTTTTAATAGACTTTTCTAATTCTTTAGTTATAACATTATTCGTAAATTTATTTAAATAA

Upstream 100 bases:

>100_bases
ATATATATTTGAATTTTCATATTTATGAATATTTTTTTTTATTTCTATCATAAGTGATCATATAAACATAATATTGATTA
CATTATAAGGGGGATTTTTT

Downstream 100 bases:

>100_bases
TCCAATAAAAAATATAGCTAAGTAATATATAAATTAACCTGTTGTGCTAAAAGATAAGTTTTCATTAACAGGATTAATAT
ACCATATCACATAGGCACTG

Product: sodium/glutamate symporter

Products: Na (I) [Cytoplasm]; L-glutamate [Cytoplasm] [C]

Alternate protein names: Glutamate permease [H]

Number of amino acids: Translated: 394; Mature: 393

Protein sequence:

>394_residues
MTLELDMIQTTTLAIFFYYIGVFIKSKVSILEKFCIPAPVVGGLIFAILNLIFTESGFISISLDTTLQKPFMLAFFTTIG
LGASFKMIKQGGLHVIMFFIAALLLVISQDFLGVVMAKFIGEDPLLGLIVGSVTMTGGHGTGATFGALFESEYGLVGAST
TAMAAATFGLVCGSLIGGPIAKNLISKNNLKNNSDEFFETNSDDCEEVSYKTLFNTFSLIFISMGLGSILEMFFTNLGIV
LPSYIDAMIVAAIILNIGEQTNKWKINSKCADIIGSMSLNVFLSMALISLKLWELKSTAGPLLILLIGQAVLMFMFAYFI
TFRLMGKDYDAAVMSSGHCGFGMGATPNGIANMEAITSKYGASPKAFFILPVVGAFLIDFSNSLVITLFVNLFK

Sequences:

>Translated_394_residues
MTLELDMIQTTTLAIFFYYIGVFIKSKVSILEKFCIPAPVVGGLIFAILNLIFTESGFISISLDTTLQKPFMLAFFTTIG
LGASFKMIKQGGLHVIMFFIAALLLVISQDFLGVVMAKFIGEDPLLGLIVGSVTMTGGHGTGATFGALFESEYGLVGAST
TAMAAATFGLVCGSLIGGPIAKNLISKNNLKNNSDEFFETNSDDCEEVSYKTLFNTFSLIFISMGLGSILEMFFTNLGIV
LPSYIDAMIVAAIILNIGEQTNKWKINSKCADIIGSMSLNVFLSMALISLKLWELKSTAGPLLILLIGQAVLMFMFAYFI
TFRLMGKDYDAAVMSSGHCGFGMGATPNGIANMEAITSKYGASPKAFFILPVVGAFLIDFSNSLVITLFVNLFK
>Mature_393_residues
TLELDMIQTTTLAIFFYYIGVFIKSKVSILEKFCIPAPVVGGLIFAILNLIFTESGFISISLDTTLQKPFMLAFFTTIGL
GASFKMIKQGGLHVIMFFIAALLLVISQDFLGVVMAKFIGEDPLLGLIVGSVTMTGGHGTGATFGALFESEYGLVGASTT
AMAAATFGLVCGSLIGGPIAKNLISKNNLKNNSDEFFETNSDDCEEVSYKTLFNTFSLIFISMGLGSILEMFFTNLGIVL
PSYIDAMIVAAIILNIGEQTNKWKINSKCADIIGSMSLNVFLSMALISLKLWELKSTAGPLLILLIGQAVLMFMFAYFIT
FRLMGKDYDAAVMSSGHCGFGMGATPNGIANMEAITSKYGASPKAFFILPVVGAFLIDFSNSLVITLFVNLFK

Specific function: Catalyzes the sodium-dependent uptake of extracellular glutamate [H]

COG id: COG0786

COG function: function code E; Na+/glutamate symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gltS symporter family [H]

Homologues:

Organism=Escherichia coli, GI1790085, Length=372, Percent_Identity=42.4731182795699, Blast_Score=269, Evalue=2e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004445 [H]

Pfam domain/function: PF03616 Glt_symporter [H]

EC number: NA

Molecular weight: Translated: 42399; Mature: 42268

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLELDMIQTTTLAIFFYYIGVFIKSKVSILEKFCIPAPVVGGLIFAILNLIFTESGFIS
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEE
ISLDTTLQKPFMLAFFTTIGLGASFKMIKQGGLHVIMFFIAALLLVISQDFLGVVMAKFI
EEECCHHCCHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GEDPLLGLIVGSVTMTGGHGTGATFGALFESEYGLVGASTTAMAAATFGLVCGSLIGGPI
CCCCHHHHEEHHEEEECCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCHHH
AKNLISKNNLKNNSDEFFETNSDDCEEVSYKTLFNTFSLIFISMGLGSILEMFFTNLGIV
HHHHHHHCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPSYIDAMIVAAIILNIGEQTNKWKINSKCADIIGSMSLNVFLSMALISLKLWELKSTAG
HHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PLLILLIGQAVLMFMFAYFITFRLMGKDYDAAVMSSGHCGFGMGATPNGIANMEAITSKY
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHH
GASPKAFFILPVVGAFLIDFSNSLVITLFVNLFK
CCCCCEEEHHHHHHHHHHHCCCCCHHHHHHHHHC
>Mature Secondary Structure 
TLELDMIQTTTLAIFFYYIGVFIKSKVSILEKFCIPAPVVGGLIFAILNLIFTESGFIS
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEE
ISLDTTLQKPFMLAFFTTIGLGASFKMIKQGGLHVIMFFIAALLLVISQDFLGVVMAKFI
EEECCHHCCHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GEDPLLGLIVGSVTMTGGHGTGATFGALFESEYGLVGASTTAMAAATFGLVCGSLIGGPI
CCCCHHHHEEHHEEEECCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCHHH
AKNLISKNNLKNNSDEFFETNSDDCEEVSYKTLFNTFSLIFISMGLGSILEMFFTNLGIV
HHHHHHHCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPSYIDAMIVAAIILNIGEQTNKWKINSKCADIIGSMSLNVFLSMALISLKLWELKSTAG
HHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PLLILLIGQAVLMFMFAYFITFRLMGKDYDAAVMSSGHCGFGMGATPNGIANMEAITSKY
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHH
GASPKAFFILPVVGAFLIDFSNSLVITLFVNLFK
CCCCCEEEHHHHHHHHHHHCCCCCHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; L-glutamate [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + L-glutamate [Periplasm] = Na (I) [Cytoplasm] + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]