Click here to switch to the map view.

The map label for this gene is asnC [H]

Identifier: 226947851

GI number: 226947851

Start: 760919

End: 762310

Strand: Direct

Name: asnC [H]

Synonym: CLM_0706

Alternate gene names: 226947851

Gene position: 760919-762310 (Clockwise)

Preceding gene: 226947848

Following gene: 226947852

Centisome position: 18.31

GC content: 31.82

Gene sequence:

>1392_bases
ATGGATATAACTTTAGTAAAATCACTTTATAGAGAAACAGAAAAATACATGGATAAAGAAGTTAAAATTAATGGATGGGT
AAGAACTGTAAGAGATTCTAAAAACTTTGCCTTTGTAGAAGTAAATGACGGAAGTTTCTTTAAAAATGTTCAAGTAATAC
TTGAGTCTTCTTTAGAAAACTTTAAGGAACTATGTAAAATGCCAATAAGTACATCAGTAGAAGTAGAGGGAATAGTTCAA
CCTACACCAAATGCAAAGCAACCTTTCGAAATAAAGGCTACAAGAGTTTCAATAGAAGGTAAATCAAGCACAGATTATCC
TCTACAAAAGAAAAGACATACCTTTGAATATTTAAGAACTATAGCTCATTTAAGACCAAGAAGCAATGCTTTTTCAGCAG
TATTTAGAGTACGTTCTTTAGCAGCTTATGCAGTGCATAAATTTTTCCAAGAAAGAGGATTTGTTTATACAAATACTCCA
ATAATAACAGGTAGTGACTGTGAAGGGGCAGGAGAAATGTTCCAATTAACTACTATGGATTTAAACAATATACCAAAAAC
TGAAGAAGGAAAAATAGATTTTTCAAAGGATTTCTTTGGATCACCTGCAAACCTTACAGTAAGTGGTCAGCTTTCAGCAG
AAACTTTTGCGTTAGCTTTTAGAAACGTATATACTTTTGGACCAACTTTTAGAGCAGAAAATTCAAACACTGCAAGACAC
GCATCAGAATTTTGGATGATAGAACCTGAAATGGCCTTTGCAGAACTTACAGATTATTTAGATAATGCAGAGGATATGGT
TAAATTTGTAATAAACTATGTAATGGAAAATGCTCCAGAAGAAATGGCATTCTTCAATAGTTTCGTAGATAAAGGTTTAT
TTGATAGATTAGATAATGTTGTAAACTCTGACTTCAAGAGAATAACTTATACAGAAGCAGTTGAATTACTTCAAAAATCA
GGAGCAAAATTTGATTATGAAGTAGAATGGGGAATAGACCTTCAAACTGAACATGAAAGATATTTAACAGAACAAATATT
TAAAAAACCAGTATTTGTAACAGATTATCCAAAGGACATAAAAGCTTTCTATATGAGATTAAATGATGATGGAAAAACTG
TTGCAGCAGCGGATTTACTTGTACCAGGAGTAGGAGAAATTATAGGTGGAAGCCAAAGGGAAGAAAGATTAGATGTATTA
GAAAAAAGAATGGAAGAATTAAACCTTAATAAAGAAGATTACTGGTGGTATTTAGAATTAAGAAAATATGGAGAAACTAA
ACACTCAGGATATGGTTTAGGTTTCGAAAGAATATTAATGTACATCACAGGAATGACTAATATAAGAGATGTAATACCAT
TCCCAAGAACTCCAGGCTCAGCTGAATTCTAA

Upstream 100 bases:

>100_bases
TGGCAATTTGGGTGGTACCGCGGAATATATACCTTTCGTCCCTTTTGGGATGAAGGGTTTTTTTATATTATGAAATAAAA
TCCAAAGAGGAGGAAAAAAC

Downstream 100 bases:

>100_bases
AATAAAAAATATTTAAGTTGATTATATAATTTAAAATGAAAAAATATAATAAAAATAAAAGGAATTTATAATACACAAAA
TAACCTAAACTGCCTATAGG

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS [H]

Number of amino acids: Translated: 463; Mature: 463

Protein sequence:

>463_residues
MDITLVKSLYRETEKYMDKEVKINGWVRTVRDSKNFAFVEVNDGSFFKNVQVILESSLENFKELCKMPISTSVEVEGIVQ
PTPNAKQPFEIKATRVSIEGKSSTDYPLQKKRHTFEYLRTIAHLRPRSNAFSAVFRVRSLAAYAVHKFFQERGFVYTNTP
IITGSDCEGAGEMFQLTTMDLNNIPKTEEGKIDFSKDFFGSPANLTVSGQLSAETFALAFRNVYTFGPTFRAENSNTARH
ASEFWMIEPEMAFAELTDYLDNAEDMVKFVINYVMENAPEEMAFFNSFVDKGLFDRLDNVVNSDFKRITYTEAVELLQKS
GAKFDYEVEWGIDLQTEHERYLTEQIFKKPVFVTDYPKDIKAFYMRLNDDGKTVAAADLLVPGVGEIIGGSQREERLDVL
EKRMEELNLNKEDYWWYLELRKYGETKHSGYGLGFERILMYITGMTNIRDVIPFPRTPGSAEF

Sequences:

>Translated_463_residues
MDITLVKSLYRETEKYMDKEVKINGWVRTVRDSKNFAFVEVNDGSFFKNVQVILESSLENFKELCKMPISTSVEVEGIVQ
PTPNAKQPFEIKATRVSIEGKSSTDYPLQKKRHTFEYLRTIAHLRPRSNAFSAVFRVRSLAAYAVHKFFQERGFVYTNTP
IITGSDCEGAGEMFQLTTMDLNNIPKTEEGKIDFSKDFFGSPANLTVSGQLSAETFALAFRNVYTFGPTFRAENSNTARH
ASEFWMIEPEMAFAELTDYLDNAEDMVKFVINYVMENAPEEMAFFNSFVDKGLFDRLDNVVNSDFKRITYTEAVELLQKS
GAKFDYEVEWGIDLQTEHERYLTEQIFKKPVFVTDYPKDIKAFYMRLNDDGKTVAAADLLVPGVGEIIGGSQREERLDVL
EKRMEELNLNKEDYWWYLELRKYGETKHSGYGLGFERILMYITGMTNIRDVIPFPRTPGSAEF
>Mature_463_residues
MDITLVKSLYRETEKYMDKEVKINGWVRTVRDSKNFAFVEVNDGSFFKNVQVILESSLENFKELCKMPISTSVEVEGIVQ
PTPNAKQPFEIKATRVSIEGKSSTDYPLQKKRHTFEYLRTIAHLRPRSNAFSAVFRVRSLAAYAVHKFFQERGFVYTNTP
IITGSDCEGAGEMFQLTTMDLNNIPKTEEGKIDFSKDFFGSPANLTVSGQLSAETFALAFRNVYTFGPTFRAENSNTARH
ASEFWMIEPEMAFAELTDYLDNAEDMVKFVINYVMENAPEEMAFFNSFVDKGLFDRLDNVVNSDFKRITYTEAVELLQKS
GAKFDYEVEWGIDLQTEHERYLTEQIFKKPVFVTDYPKDIKAFYMRLNDDGKTVAAADLLVPGVGEIIGGSQREERLDVL
EKRMEELNLNKEDYWWYLELRKYGETKHSGYGLGFERILMYITGMTNIRDVIPFPRTPGSAEF

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI226491502, Length=446, Percent_Identity=45.7399103139013, Blast_Score=401, Evalue=1e-112,
Organism=Homo sapiens, GI4758762, Length=453, Percent_Identity=28.6975717439294, Blast_Score=182, Evalue=7e-46,
Organism=Homo sapiens, GI45439306, Length=354, Percent_Identity=28.2485875706215, Blast_Score=116, Evalue=4e-26,
Organism=Escherichia coli, GI1787161, Length=451, Percent_Identity=56.5410199556541, Blast_Score=543, Evalue=1e-156,
Organism=Escherichia coli, GI1788173, Length=109, Percent_Identity=33.9449541284404, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1790571, Length=368, Percent_Identity=24.4565217391304, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71984122, Length=464, Percent_Identity=32.1120689655172, Blast_Score=214, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI17556372, Length=426, Percent_Identity=31.6901408450704, Blast_Score=205, Evalue=3e-53,
Organism=Caenorhabditis elegans, GI17551876, Length=477, Percent_Identity=25.1572327044025, Blast_Score=111, Evalue=9e-25,
Organism=Saccharomyces cerevisiae, GI6319872, Length=490, Percent_Identity=39.5918367346939, Blast_Score=331, Evalue=1e-91,
Organism=Saccharomyces cerevisiae, GI6321807, Length=459, Percent_Identity=28.5403050108932, Blast_Score=195, Evalue=1e-50,
Organism=Saccharomyces cerevisiae, GI6323011, Length=343, Percent_Identity=29.1545189504373, Blast_Score=123, Evalue=5e-29,
Organism=Drosophila melanogaster, GI19922416, Length=450, Percent_Identity=36.2222222222222, Blast_Score=266, Evalue=2e-71,
Organism=Drosophila melanogaster, GI19921528, Length=456, Percent_Identity=28.7280701754386, Blast_Score=164, Evalue=9e-41,
Organism=Drosophila melanogaster, GI17136276, Length=356, Percent_Identity=26.4044943820225, Blast_Score=99, Evalue=4e-21,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.22 [H]

Molecular weight: Translated: 53308; Mature: 53308

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDITLVKSLYRETEKYMDKEVKINGWVRTVRDSKNFAFVEVNDGSFFKNVQVILESSLEN
CCHHHHHHHHHHHHHHCCCCEEECHHEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHH
FKELCKMPISTSVEVEGIVQPTPNAKQPFEIKATRVSIEGKSSTDYPLQKKRHTFEYLRT
HHHHHCCCCCCCEEEEEEECCCCCCCCCEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHH
IAHLRPRSNAFSAVFRVRSLAAYAVHKFFQERGFVYTNTPIITGSDCEGAGEMFQLTTMD
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCEEECCCCCCCCCEEEEEEEC
LNNIPKTEEGKIDFSKDFFGSPANLTVSGQLSAETFALAFRNVYTFGPTFRAENSNTARH
CCCCCCCCCCCEEECHHHCCCCCCEEEECCCCHHHHHHHHHHHHCCCCEEECCCCCCHHH
ASEFWMIEPEMAFAELTDYLDNAEDMVKFVINYVMENAPEEMAFFNSFVDKGLFDRLDNV
HHHEEEECCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
VNSDFKRITYTEAVELLQKSGAKFDYEVEWGIDLQTEHERYLTEQIFKKPVFVTDYPKDI
HCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCEEECCCHHH
KAFYMRLNDDGKTVAAADLLVPGVGEIIGGSQREERLDVLEKRMEELNLNKEDYWWYLEL
HEEEEEECCCCCEEEEHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEE
RKYGETKHSGYGLGFERILMYITGMTNIRDVIPFPRTPGSAEF
ECCCCCCCCCCCCCHHHHHHHHHCCCHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MDITLVKSLYRETEKYMDKEVKINGWVRTVRDSKNFAFVEVNDGSFFKNVQVILESSLEN
CCHHHHHHHHHHHHHHCCCCEEECHHEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHH
FKELCKMPISTSVEVEGIVQPTPNAKQPFEIKATRVSIEGKSSTDYPLQKKRHTFEYLRT
HHHHHCCCCCCCEEEEEEECCCCCCCCCEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHH
IAHLRPRSNAFSAVFRVRSLAAYAVHKFFQERGFVYTNTPIITGSDCEGAGEMFQLTTMD
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCEEECCCCCCCCCEEEEEEEC
LNNIPKTEEGKIDFSKDFFGSPANLTVSGQLSAETFALAFRNVYTFGPTFRAENSNTARH
CCCCCCCCCCCEEECHHHCCCCCCEEEECCCCHHHHHHHHHHHHCCCCEEECCCCCCHHH
ASEFWMIEPEMAFAELTDYLDNAEDMVKFVINYVMENAPEEMAFFNSFVDKGLFDRLDNV
HHHEEEECCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
VNSDFKRITYTEAVELLQKSGAKFDYEVEWGIDLQTEHERYLTEQIFKKPVFVTDYPKDI
HCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCEEECCCHHH
KAFYMRLNDDGKTVAAADLLVPGVGEIIGGSQREERLDVLEKRMEELNLNKEDYWWYLEL
HEEEEEECCCCCEEEEHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEE
RKYGETKHSGYGLGFERILMYITGMTNIRDVIPFPRTPGSAEF
ECCCCCCCCCCCCCHHHHHHHHHCCCHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA