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The map label for this gene is flp [H]

Identifier: 226947535

GI number: 226947535

Start: 363732

End: 365243

Strand: Direct

Name: flp [H]

Synonym: CLM_0371

Alternate gene names: 226947535

Gene position: 363732-365243 (Clockwise)

Preceding gene: 226947534

Following gene: 226947536

Centisome position: 8.75

GC content: 26.85

Gene sequence:

>1512_bases
ATGAAAAAAATAAATAAATATTTAATTATACTTAGTGCTTTTTTAAGTATAATTTTATTATCATTTGAAACCTATGCTTT
AGAAAATAATAGAAATGGAATAAATTATTTATCAAGTGATGAGAATTCAAAAATAGAAAAATTTGTAGAAGAAAATATGG
ACAAGGGAAAGATTCCAGGGCTATCTGTAACTATAGTTAAAGGCGATAAGACTGTTTATCAAAAAGGTTTTGGCTACTCA
GATATAGAATTACAAAAATCTGTTGATTCTGAATCCTTGTTTGAAATAGGATCTAATAGCAAGGCATTTACTGCTTTAGG
CATTTTAGATTTACAAAAGAATGGTTTAATTAAATTCGATGATGAAGTAACTAAATATATACCTTGGCTAAAGGTTAAAT
ATAAAGGTAAAGAAGTGCCAATAACTATAGAACAATTAGTACATCATACAAGTGGAGTATCTTTTAATACAATAGATAAG
ATACCAGTCTCCAATGAAGATAATGCACTTTATGAAACTGTTAAAACATTGATAGGTATAGAATTAGATAATGAACCAGG
TAAAAGCTTTCAATATGCAACTATAAATTATGATGTTTTAGGATTAATAATTCAAGAGGTGACAGGGAAGTCTTATGAAA
ATTATATTGAAGAAAATATTCTAAAACCAATGGGCTTAAGTAATACTTATCTTTATAGAAATGAAAACGTTAATAAACAT
ATGGCTAAAGGATATAAAGTTTCATTTTTAAGACCACATGAATATGATGCACCTATTTATAGAGGAAATAAACCAGCTGG
ATATATTATATCTAATGGCGAAGATATGGGAAAATGGCTTAAAATTCAGATGGGAACTTTAAGTGATTTAAAATTTCATA
AAAATTTAATTGAAGAATCTCATAATGCTAATGATACAATCGCCCCTTTAAGGGATGGATCATCATATGCTAGTGGATGG
CTTGTTTACGAAAAAGGTAGTAGAGAGATTTCTCATGCAGGAAATAATCCTAATTACTCTTCATTTATATTATTTAGACC
TGAAGATAAAGTAGGTGTTGCAATACTTAGCAATACTAGCTCACAATATATACCAGCTATAACTCAAGGAATTAATGAAA
TATTACAAGGGAGAGTCTATAACAAGGACATAAAAGACTTAAATAAAAGCGCAGATAAAATCTCAATATTAATTATAGCT
ATTTCTGTTTTATTAATTATTACTACCATTTTTTTTATGGGAAAAGCATTAAAAGATATATTTGAAAAAGAAAGAAGTTT
GAAGAAGAAGAGATTAAAAAGCATTTTAAAAATTATTTTTTCTTTAATTTTTATGCTGGGTATAAGTTACTCAATATATT
TGATTCCATACATTTTGTATAGGGGAGTATCCTGGGAGTTTATATTTGTATGGCTTCCTAAAACTGCTAAAATAGCATTT
TATTTAGTATATGTAAGCATTTGGATAGTATATATATATTCCATATTTACAAGCTTTTATAAAAAAAGATGA

Upstream 100 bases:

>100_bases
AACACCAATAACAGAAGGTTTATATTTACCATAGATGAGAAATGTTATGTGTAAAAAATTCCAAAAAAGTATTTCAGATC
ATATAAGGAGCAAGATTATT

Downstream 100 bases:

>100_bases
TAGATCTATACTGATATTATCCTAATAGAGGTAACAAATGAAATTGTGTATTTAAAGAGGATGGAAATTGTTAAGTATTT
ATTAAGAGCTTCATGTTATT

Product: beta-lactamase

Products: NA

Alternate protein names: FmtA-like protein [H]

Number of amino acids: Translated: 503; Mature: 503

Protein sequence:

>503_residues
MKKINKYLIILSAFLSIILLSFETYALENNRNGINYLSSDENSKIEKFVEENMDKGKIPGLSVTIVKGDKTVYQKGFGYS
DIELQKSVDSESLFEIGSNSKAFTALGILDLQKNGLIKFDDEVTKYIPWLKVKYKGKEVPITIEQLVHHTSGVSFNTIDK
IPVSNEDNALYETVKTLIGIELDNEPGKSFQYATINYDVLGLIIQEVTGKSYENYIEENILKPMGLSNTYLYRNENVNKH
MAKGYKVSFLRPHEYDAPIYRGNKPAGYIISNGEDMGKWLKIQMGTLSDLKFHKNLIEESHNANDTIAPLRDGSSYASGW
LVYEKGSREISHAGNNPNYSSFILFRPEDKVGVAILSNTSSQYIPAITQGINEILQGRVYNKDIKDLNKSADKISILIIA
ISVLLIITTIFFMGKALKDIFEKERSLKKKRLKSILKIIFSLIFMLGISYSIYLIPYILYRGVSWEFIFVWLPKTAKIAF
YLVYVSIWIVYIYSIFTSFYKKR

Sequences:

>Translated_503_residues
MKKINKYLIILSAFLSIILLSFETYALENNRNGINYLSSDENSKIEKFVEENMDKGKIPGLSVTIVKGDKTVYQKGFGYS
DIELQKSVDSESLFEIGSNSKAFTALGILDLQKNGLIKFDDEVTKYIPWLKVKYKGKEVPITIEQLVHHTSGVSFNTIDK
IPVSNEDNALYETVKTLIGIELDNEPGKSFQYATINYDVLGLIIQEVTGKSYENYIEENILKPMGLSNTYLYRNENVNKH
MAKGYKVSFLRPHEYDAPIYRGNKPAGYIISNGEDMGKWLKIQMGTLSDLKFHKNLIEESHNANDTIAPLRDGSSYASGW
LVYEKGSREISHAGNNPNYSSFILFRPEDKVGVAILSNTSSQYIPAITQGINEILQGRVYNKDIKDLNKSADKISILIIA
ISVLLIITTIFFMGKALKDIFEKERSLKKKRLKSILKIIFSLIFMLGISYSIYLIPYILYRGVSWEFIFVWLPKTAKIAF
YLVYVSIWIVYIYSIFTSFYKKR
>Mature_503_residues
MKKINKYLIILSAFLSIILLSFETYALENNRNGINYLSSDENSKIEKFVEENMDKGKIPGLSVTIVKGDKTVYQKGFGYS
DIELQKSVDSESLFEIGSNSKAFTALGILDLQKNGLIKFDDEVTKYIPWLKVKYKGKEVPITIEQLVHHTSGVSFNTIDK
IPVSNEDNALYETVKTLIGIELDNEPGKSFQYATINYDVLGLIIQEVTGKSYENYIEENILKPMGLSNTYLYRNENVNKH
MAKGYKVSFLRPHEYDAPIYRGNKPAGYIISNGEDMGKWLKIQMGTLSDLKFHKNLIEESHNANDTIAPLRDGSSYASGW
LVYEKGSREISHAGNNPNYSSFILFRPEDKVGVAILSNTSSQYIPAITQGINEILQGRVYNKDIKDLNKSADKISILIIA
ISVLLIITTIFFMGKALKDIFEKERSLKKKRLKSILKIIFSLIFMLGISYSIYLIPYILYRGVSWEFIFVWLPKTAKIAF
YLVYVSIWIVYIYSIFTSFYKKR

Specific function: Its precise function is unknown. Has no penicillin- binding activity and is not involved in methicillin resistance [H]

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI87082101, Length=287, Percent_Identity=25.7839721254355, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1790593, Length=276, Percent_Identity=26.4492753623188, Blast_Score=86, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI115533026, Length=371, Percent_Identity=26.9541778975741, Blast_Score=102, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17550934, Length=330, Percent_Identity=26.0606060606061, Blast_Score=89, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: NA

Molecular weight: Translated: 57402; Mature: 57402

Theoretical pI: Translated: 9.39; Mature: 9.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKINKYLIILSAFLSIILLSFETYALENNRNGINYLSSDENSKIEKFVEENMDKGKIPG
CCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCC
LSVTIVKGDKTVYQKGFGYSDIELQKSVDSESLFEIGSNSKAFTALGILDLQKNGLIKFD
EEEEEEECCHHHHHCCCCCCCCHHHHCCCHHHHHHCCCCCCEEEEEEEEEECCCCCEEEC
DEVTKYIPWLKVKYKGKEVPITIEQLVHHTSGVSFNTIDKIPVSNEDNALYETVKTLIGI
CHHHHHCCCEEEEECCCCCCEEHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCE
ELDNEPGKSFQYATINYDVLGLIIQEVTGKSYENYIEENILKPMGLSNTYLYRNENVNKH
EECCCCCCCEEEEEECHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCEEEEECCCCCHH
MAKGYKVSFLRPHEYDAPIYRGNKPAGYIISNGEDMGKWLKIQMGTLSDLKFHKNLIEES
HHCCCEEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEECCCHHHHHHHHHHHHC
HNANDTIAPLRDGSSYASGWLVYEKGSREISHAGNNPNYSSFILFRPEDKVGVAILSNTS
CCCCCCCCCCCCCCCCCCCEEEEECCCCHHHCCCCCCCCCEEEEECCCCCEEEEEEECCC
SQYIPAITQGINEILQGRVYNKDIKDLNKSADKISILIIAISVLLIITTIFFMGKALKDI
CCCHHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FEKERSLKKKRLKSILKIIFSLIFMLGISYSIYLIPYILYRGVSWEFIFVWLPKTAKIAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEEECCCCHHHHH
YLVYVSIWIVYIYSIFTSFYKKR
HHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKINKYLIILSAFLSIILLSFETYALENNRNGINYLSSDENSKIEKFVEENMDKGKIPG
CCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCC
LSVTIVKGDKTVYQKGFGYSDIELQKSVDSESLFEIGSNSKAFTALGILDLQKNGLIKFD
EEEEEEECCHHHHHCCCCCCCCHHHHCCCHHHHHHCCCCCCEEEEEEEEEECCCCCEEEC
DEVTKYIPWLKVKYKGKEVPITIEQLVHHTSGVSFNTIDKIPVSNEDNALYETVKTLIGI
CHHHHHCCCEEEEECCCCCCEEHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCE
ELDNEPGKSFQYATINYDVLGLIIQEVTGKSYENYIEENILKPMGLSNTYLYRNENVNKH
EECCCCCCCEEEEEECHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCEEEEECCCCCHH
MAKGYKVSFLRPHEYDAPIYRGNKPAGYIISNGEDMGKWLKIQMGTLSDLKFHKNLIEES
HHCCCEEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEECCCHHHHHHHHHHHHC
HNANDTIAPLRDGSSYASGWLVYEKGSREISHAGNNPNYSSFILFRPEDKVGVAILSNTS
CCCCCCCCCCCCCCCCCCCEEEEECCCCHHHCCCCCCCCCEEEEECCCCCEEEEEEECCC
SQYIPAITQGINEILQGRVYNKDIKDLNKSADKISILIIAISVLLIITTIFFMGKALKDI
CCCHHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FEKERSLKKKRLKSILKIIFSLIFMLGISYSIYLIPYILYRGVSWEFIFVWLPKTAKIAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEEECCCCHHHHH
YLVYVSIWIVYIYSIFTSFYKKR
HHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA