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The map label for this gene is ycbM [H]

Identifier: 226947467

GI number: 226947467

Start: 287778

End: 288686

Strand: Direct

Name: ycbM [H]

Synonym: CLM_0298

Alternate gene names: 226947467

Gene position: 287778-288686 (Clockwise)

Preceding gene: 226947466

Following gene: 226947468

Centisome position: 6.93

GC content: 25.3

Gene sequence:

>909_bases
ATGTATTTATTAGCTGTTATTTTATTTGTGATTTTTATAATTATATTTTCAGTAGTAATGTGTATTAAATTATTTTCATA
TAAAAGGCAAATACGGGATATCACTAATCAGATTAGAGAGTTTAAAGAGAGAAAAACAAATAAAAAGATTAATACTCAAA
TAGCAGATAAAGATATAGAAGAGCTTGCTTGTGAGGTTAATGAGTACCTAGAACTCTATAAAAGGAATGAACAAGAAAAG
ATAGTATTTGAAAACACATTAAAACAAGGAATAGCTAATATGTCTCATGATTTAAGAACCCCATTAACTTCAATAATAGG
GTACTTAAAGTTACTTCAAAATGATGAAATAGATAAGAAAGAAGCACTAGATATACTTAAAAATAAAACTAATAAGTTAA
ATATACTTATAAATGATTTTTTTGAGTTAGCTTCAATAGAAAGTGAAGATTATGAATTAGATATGATAAAAGTAAATTTA
ACTAATGTAGTACGTGATGAAATCTTATCACTTTATGAAGCTTTTCAAGGCAAAGGACTTGAACCAAAGATAAATATTTT
AGATAAACCAATTTTTATAATGAGCGATAAGGATAGCTTAGAGAGAATAATAGATAATTTACTTTCTAATACATTGAAAT
ATGCAGAAAAAGATATTGAAATAAATTTAGAAGAATCTAATGATAAAGTTATTTTAAAAATCTCCAATATATGTACAAGC
ATTGATGAAAAAGATGTATTACATATGTTCGATAGATTTTATATGGCAGATAAGGTAAGAAAAGGACAAGGAACAGGACT
TGGCCTTTCTATTGTAAAAAGTTTAATGGAAAAGATGGACGGAATCATAACCTCAAAGTTTGAACAAAATAGGGTTTCTA
TAATATGCGAATGGAAATATATAAAATAA

Upstream 100 bases:

>100_bases
AGATATTAAGTAATTGAGATAAAAAGATTATTTGATATGTAAAGCATGAAGATATTAAATAATTAAGAAAAAATCTATTA
TATAAATTAGGAGAATTGAG

Downstream 100 bases:

>100_bases
TATTGTTTTATATATTCACGACCGCCCATGAGTAGCTTAAATAGTTGCTTACAGGCAGTTGTGCTTTTTTCTACCGTGTA
TTGTTGGGAATAGGAGTTTA

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MYLLAVILFVIFIIIFSVVMCIKLFSYKRQIRDITNQIREFKERKTNKKINTQIADKDIEELACEVNEYLELYKRNEQEK
IVFENTLKQGIANMSHDLRTPLTSIIGYLKLLQNDEIDKKEALDILKNKTNKLNILINDFFELASIESEDYELDMIKVNL
TNVVRDEILSLYEAFQGKGLEPKINILDKPIFIMSDKDSLERIIDNLLSNTLKYAEKDIEINLEESNDKVILKISNICTS
IDEKDVLHMFDRFYMADKVRKGQGTGLGLSIVKSLMEKMDGIITSKFEQNRVSIICEWKYIK

Sequences:

>Translated_302_residues
MYLLAVILFVIFIIIFSVVMCIKLFSYKRQIRDITNQIREFKERKTNKKINTQIADKDIEELACEVNEYLELYKRNEQEK
IVFENTLKQGIANMSHDLRTPLTSIIGYLKLLQNDEIDKKEALDILKNKTNKLNILINDFFELASIESEDYELDMIKVNL
TNVVRDEILSLYEAFQGKGLEPKINILDKPIFIMSDKDSLERIIDNLLSNTLKYAEKDIEINLEESNDKVILKISNICTS
IDEKDVLHMFDRFYMADKVRKGQGTGLGLSIVKSLMEKMDGIITSKFEQNRVSIICEWKYIK
>Mature_302_residues
MYLLAVILFVIFIIIFSVVMCIKLFSYKRQIRDITNQIREFKERKTNKKINTQIADKDIEELACEVNEYLELYKRNEQEK
IVFENTLKQGIANMSHDLRTPLTSIIGYLKLLQNDEIDKKEALDILKNKTNKLNILINDFFELASIESEDYELDMIKVNL
TNVVRDEILSLYEAFQGKGLEPKINILDKPIFIMSDKDSLERIIDNLLSNTLKYAEKDIEINLEESNDKVILKISNICTS
IDEKDVLHMFDRFYMADKVRKGQGTGLGLSIVKSLMEKMDGIITSKFEQNRVSIICEWKYIK

Specific function: Member of the two-component regulatory system ycbM/ycbL. Probably activates ycbL by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=238, Percent_Identity=32.7731092436975, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI145693157, Length=214, Percent_Identity=31.7757009345794, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1788393, Length=253, Percent_Identity=25.6916996047431, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1786783, Length=285, Percent_Identity=24.2105263157895, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1790346, Length=202, Percent_Identity=26.7326732673267, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1786912, Length=232, Percent_Identity=29.3103448275862, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI48994928, Length=246, Percent_Identity=26.4227642276423, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1788713, Length=203, Percent_Identity=26.1083743842365, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786600, Length=201, Percent_Identity=26.865671641791, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787894, Length=296, Percent_Identity=23.9864864864865, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI87082128, Length=213, Percent_Identity=25.3521126760563, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787374, Length=288, Percent_Identity=20.1388888888889, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87081816, Length=248, Percent_Identity=22.9838709677419, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 35275; Mature: 35275

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLLAVILFVIFIIIFSVVMCIKLFSYKRQIRDITNQIREFKERKTNKKINTQIADKDIE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
ELACEVNEYLELYKRNEQEKIVFENTLKQGIANMSHDLRTPLTSIIGYLKLLQNDEIDKK
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
EALDILKNKTNKLNILINDFFELASIESEDYELDMIKVNLTNVVRDEILSLYEAFQGKGL
HHHHHHHCCCCEEEEHHHHHHHHHHCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHCCCCC
EPKINILDKPIFIMSDKDSLERIIDNLLSNTLKYAEKDIEINLEESNDKVILKISNICTS
CCCHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEEHHHHHC
IDEKDVLHMFDRFYMADKVRKGQGTGLGLSIVKSLMEKMDGIITSKFEQNRVSIICEWKY
CCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEE
IK
CC
>Mature Secondary Structure
MYLLAVILFVIFIIIFSVVMCIKLFSYKRQIRDITNQIREFKERKTNKKINTQIADKDIE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
ELACEVNEYLELYKRNEQEKIVFENTLKQGIANMSHDLRTPLTSIIGYLKLLQNDEIDKK
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
EALDILKNKTNKLNILINDFFELASIESEDYELDMIKVNLTNVVRDEILSLYEAFQGKGL
HHHHHHHCCCCEEEEHHHHHHHHHHCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHCCCCC
EPKINILDKPIFIMSDKDSLERIIDNLLSNTLKYAEKDIEINLEESNDKVILKISNICTS
CCCHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEEHHHHHC
IDEKDVLHMFDRFYMADKVRKGQGTGLGLSIVKSLMEKMDGIITSKFEQNRVSIICEWKY
CCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEE
IK
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]