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The map label for this gene is gap [H]

Identifier: 226947447

GI number: 226947447

Start: 262175

End: 263182

Strand: Direct

Name: gap [H]

Synonym: CLM_0276

Alternate gene names: 226947447

Gene position: 262175-263182 (Clockwise)

Preceding gene: 226947446

Following gene: 226947448

Centisome position: 6.31

GC content: 33.13

Gene sequence:

>1008_bases
ATGGTTAAAGTTGCTATTAATGGATTTGGAAGAATAGGAAGAAATGTGTTCAAGGCTTTGGTTAAGAACTATAAAGATGA
ATTACAAGTGGTGGCTATAAATGATTTAACAAGCCCAGCTACACTAGCTCATTTATTAAAATATGACAGTTTATATGGAA
AATTTGATGGAACTGTAGAAGCTAAAGAAACTTCAATAGTAGTTAACGGAAATGAAATAAAAATATTTGCTGAAAGAGAT
CCAAAAAATATAGACTGGAATTCAACAGGAGCAGAAATAGTAATAGAATCAACAGGTTTATTTACAGATGGAGAAAAAGC
AAATGCTCATTTAGGTGGAACAGTTAAAAAAGTTTTAATTTCAGCACCAGCTAAAAATGAAGATAAAACAATAGTTATGG
GTGTTAACCATGAAGAATACGACCCAGCAAACCATAATATAATATCAAATGCATCTTGTACAACAAACTGTTTAGCACCA
TTTGCTAAAGTTCTTGACGAAAACTTTGGAATAGAATCAGGATTAATGACAACTATTCATGCATATACAGGAGACCAAAG
AGTACTAGATGCTCCACACAAAGATTTAAGAAGAGCAAGAGCTGCAGCAGAATCAATGATACCAACAACTACAGGAGCAG
CTAAAGCAGTTGCATTAGTATTACCACAATTAAAAGGAAAATTAAACGGAATGGCTGTAAGAGTACCAACCCCAACAGTT
TCATTAACAGACTTAGTTTTCACAGTTAAAAAAGATGTAACTGTAGAAGAAATTAATGCAGCGCTTAAAAAAGCAGCTGA
AGGTGAATTAAAAGGAATATTAGGATACAGCGAAGAACCACTAGTATCAATCGACTACAGAGGAGACGAAAGATCTTCAA
TAGTTGATGCATTATCAACTAGTGTAATAGACAACAGATTAGTTAAAGTTGTTTCATGGTATGACAACGAATATGGTTAC
TCTCACAGATTAGCAGATTTAACTAAATTCGTAGCTGATAGACTTTAA

Upstream 100 bases:

>100_bases
TTAATATTTTAGAAAATGAATAATACTAAATAATTTAATTTATAAAAGATAAAAATATATATAAAAAGAAAAATGTTTAT
AATTTTAGGAGGTACTTATA

Downstream 100 bases:

>100_bases
TATAAAAAAGTATAGAGGATACTTTTAGTTAGAATATAATTTAATAATTAAAAGTTCTCCTTTTATAAGAAAAGGTTTGG
TTTCTCTATAATTCCAAACC

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH 1 [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MVKVAINGFGRIGRNVFKALVKNYKDELQVVAINDLTSPATLAHLLKYDSLYGKFDGTVEAKETSIVVNGNEIKIFAERD
PKNIDWNSTGAEIVIESTGLFTDGEKANAHLGGTVKKVLISAPAKNEDKTIVMGVNHEEYDPANHNIISNASCTTNCLAP
FAKVLDENFGIESGLMTTIHAYTGDQRVLDAPHKDLRRARAAAESMIPTTTGAAKAVALVLPQLKGKLNGMAVRVPTPTV
SLTDLVFTVKKDVTVEEINAALKKAAEGELKGILGYSEEPLVSIDYRGDERSSIVDALSTSVIDNRLVKVVSWYDNEYGY
SHRLADLTKFVADRL

Sequences:

>Translated_335_residues
MVKVAINGFGRIGRNVFKALVKNYKDELQVVAINDLTSPATLAHLLKYDSLYGKFDGTVEAKETSIVVNGNEIKIFAERD
PKNIDWNSTGAEIVIESTGLFTDGEKANAHLGGTVKKVLISAPAKNEDKTIVMGVNHEEYDPANHNIISNASCTTNCLAP
FAKVLDENFGIESGLMTTIHAYTGDQRVLDAPHKDLRRARAAAESMIPTTTGAAKAVALVLPQLKGKLNGMAVRVPTPTV
SLTDLVFTVKKDVTVEEINAALKKAAEGELKGILGYSEEPLVSIDYRGDERSSIVDALSTSVIDNRLVKVVSWYDNEYGY
SHRLADLTKFVADRL
>Mature_335_residues
MVKVAINGFGRIGRNVFKALVKNYKDELQVVAINDLTSPATLAHLLKYDSLYGKFDGTVEAKETSIVVNGNEIKIFAERD
PKNIDWNSTGAEIVIESTGLFTDGEKANAHLGGTVKKVLISAPAKNEDKTIVMGVNHEEYDPANHNIISNASCTTNCLAP
FAKVLDENFGIESGLMTTIHAYTGDQRVLDAPHKDLRRARAAAESMIPTTTGAAKAVALVLPQLKGKLNGMAVRVPTPTV
SLTDLVFTVKKDVTVEEINAALKKAAEGELKGILGYSEEPLVSIDYRGDERSSIVDALSTSVIDNRLVKVVSWYDNEYGY
SHRLADLTKFVADRL

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=335, Percent_Identity=51.6417910447761, Blast_Score=335, Evalue=3e-92,
Organism=Homo sapiens, GI7657116, Length=333, Percent_Identity=46.8468468468468, Blast_Score=325, Evalue=5e-89,
Organism=Escherichia coli, GI1788079, Length=332, Percent_Identity=51.2048192771084, Blast_Score=355, Evalue=2e-99,
Organism=Escherichia coli, GI1789295, Length=329, Percent_Identity=45.8966565349544, Blast_Score=303, Evalue=1e-83,
Organism=Caenorhabditis elegans, GI32566163, Length=338, Percent_Identity=50.887573964497, Blast_Score=337, Evalue=6e-93,
Organism=Caenorhabditis elegans, GI17568413, Length=338, Percent_Identity=50.887573964497, Blast_Score=336, Evalue=9e-93,
Organism=Caenorhabditis elegans, GI17534677, Length=338, Percent_Identity=50.5917159763314, Blast_Score=335, Evalue=3e-92,
Organism=Caenorhabditis elegans, GI17534679, Length=338, Percent_Identity=50.5917159763314, Blast_Score=333, Evalue=7e-92,
Organism=Saccharomyces cerevisiae, GI6322409, Length=334, Percent_Identity=47.9041916167665, Blast_Score=328, Evalue=7e-91,
Organism=Saccharomyces cerevisiae, GI6322468, Length=334, Percent_Identity=50.2994011976048, Blast_Score=327, Evalue=1e-90,
Organism=Saccharomyces cerevisiae, GI6321631, Length=334, Percent_Identity=49.7005988023952, Blast_Score=325, Evalue=4e-90,
Organism=Drosophila melanogaster, GI17933600, Length=336, Percent_Identity=50, Blast_Score=332, Evalue=2e-91,
Organism=Drosophila melanogaster, GI18110149, Length=336, Percent_Identity=50, Blast_Score=332, Evalue=2e-91,
Organism=Drosophila melanogaster, GI85725000, Length=336, Percent_Identity=50.297619047619, Blast_Score=332, Evalue=2e-91,
Organism=Drosophila melanogaster, GI22023983, Length=336, Percent_Identity=50.297619047619, Blast_Score=332, Evalue=2e-91,
Organism=Drosophila melanogaster, GI19922412, Length=333, Percent_Identity=46.2462462462462, Blast_Score=293, Evalue=8e-80,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 36393; Mature: 36393

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKVAINGFGRIGRNVFKALVKNYKDELQVVAINDLTSPATLAHLLKYDSLYGKFDGTVE
CEEEEECCCHHHHHHHHHHHHHHHHHCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCEEE
AKETSIVVNGNEIKIFAERDPKNIDWNSTGAEIVIESTGLFTDGEKANAHLGGTVKKVLI
ECCEEEEEECCEEEEEECCCCCCCCCCCCCCEEEEECCCCEECCCCCCCCCCHHHHHHHE
SAPAKNEDKTIVMGVNHEEYDPANHNIISNASCTTNCLAPFAKVLDENFGIESGLMTTIH
ECCCCCCCCEEEEECCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEE
AYTGDQRVLDAPHKDLRRARAAAESMIPTTTGAAKAVALVLPQLKGKLNGMAVRVPTPTV
EECCCCCEECCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCC
SLTDLVFTVKKDVTVEEINAALKKAAEGELKGILGYSEEPLVSIDYRGDERSSIVDALST
CHHHHEEECCCCCCHHHHHHHHHHHHCCCHHEECCCCCCCEEEEECCCCCHHHHHHHHHH
SVIDNRLVKVVSWYDNEYGYSHRLADLTKFVADRL
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVKVAINGFGRIGRNVFKALVKNYKDELQVVAINDLTSPATLAHLLKYDSLYGKFDGTVE
CEEEEECCCHHHHHHHHHHHHHHHHHCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCEEE
AKETSIVVNGNEIKIFAERDPKNIDWNSTGAEIVIESTGLFTDGEKANAHLGGTVKKVLI
ECCEEEEEECCEEEEEECCCCCCCCCCCCCCEEEEECCCCEECCCCCCCCCCHHHHHHHE
SAPAKNEDKTIVMGVNHEEYDPANHNIISNASCTTNCLAPFAKVLDENFGIESGLMTTIH
ECCCCCCCCEEEEECCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEE
AYTGDQRVLDAPHKDLRRARAAAESMIPTTTGAAKAVALVLPQLKGKLNGMAVRVPTPTV
EECCCCCEECCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCC
SLTDLVFTVKKDVTVEEINAALKKAAEGELKGILGYSEEPLVSIDYRGDERSSIVDALST
CHHHHEEECCCCCCHHHHHHHHHHHHCCCHHEECCCCCCCEEEEECCCCCHHHHHHHHHH
SVIDNRLVKVVSWYDNEYGYSHRLADLTKFVADRL
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA