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The map label for this gene is pgk [H]

Identifier: 226947448

GI number: 226947448

Start: 263479

End: 264675

Strand: Direct

Name: pgk [H]

Synonym: CLM_0277

Alternate gene names: 226947448

Gene position: 263479-264675 (Clockwise)

Preceding gene: 226947447

Following gene: 226947449

Centisome position: 6.34

GC content: 31.08

Gene sequence:

>1197_bases
ATGAATTATAACAAAAAAAGTATAGAATATATAGATGTAAAAGGTAAAAAAGTATTAGTAAGATGCGATTTTAATGTACC
ATTAAACGAAGGAAAAATAACAGATGAAAATAGATTAGTAGGAGCACTTCCAACAATTAAATATTTAATGGAAAAAGGTG
CTAAAATTATACTTTGTTCCCATATGGGAAAACCAAAAGGAGAACCTAAAAAAGAACTTTCATTATTACCAGTAGCCAAA
AGATTATCAGAAATGTTAAATAAAGAAGTAATATTTGCAGATGATGATAATGTAGTTGGTGAAAATGCTAAAAAAGCAGT
AGAAGATATGAAAGATGGAGATGTGGTATTACTACAAAATACTAGATATAGAAAAGAAGAAACTAAAAATGAAGAAGTTT
TTTCAAAGGAATTAGCTTCTCTTGCAGATGTATTTGTAAATGATGCATTTGGAACAGCTCACAGAGCTCATTGTTCAACA
GTAGGGGTTACAAATTATCTAAAAGAAGCTGCTTGTGGATACTTAATACAAAAAGAATTAAAATTCTTAGGAAATGCAGT
AGAAAAACCAGAAAGACCATTCGTAGCAATATTAGGTGGAGCCAAAGTTTCAGATAAAATAAATGTTATAAACAATTTAC
TAGATAAAGTAGACACATTAATAATAGGTGGAGGAATGGGATATACATTCCTAAAAGCTCAAGGATATACTATAGGAAAT
TCTTTAGTAGAAGAAGATAAAGTAGAATATTCAAAGGAAATGATAGATAAAGCTAAAGAAAAAGGAGTAAATCTATTATT
ACCAATAGATAATGTAGTAGCTGATAAATTTGATAAAGATGCAAGTCCTGTTGTAACCGAAGATCAAAATATTGGCGAAG
GATATATGGGATTAGACATAGGACCTAAAACAGCAAAAATATACTCAGATGCTATAAAATCAGCAAAAACAGTAGTATGG
AATGGACCTATGGGAGTTTTTGAATTTAAAAGTTTTGCAAATGGAACTATAGAAGTAGCTAAGGCTATGGCAGATTCTGA
TGCTGTAACAATAATAGGCGGAGGAGATAGTGCAGCGGCAGTAAATATTCTTGGATTTGGAGATAAGATGACCCATATTT
CTACAGGTGGTGGAGCTTCTCTAGAATTCTTAGAAGGAAAAGAACTACCGGGAATAGCGGCTCTTAACGATAAATAA

Upstream 100 bases:

>100_bases
ATTATAGCAACAAAGCTAAAATAGAATAAGATAGTATAGCATAAATAAATTAATTGTATATACTAATAACCCCATAATAT
TATATAAGAGGTGAATGTCA

Downstream 100 bases:

>100_bases
AAGACAGAAAATAAATAGTTACACAGTATTACTTATAAAATGTATTGGAGCGTGATTTTAAATGAGAACAGCCATAATAG
CAGGAAACTGGAAAATGAAC

Product: phosphoglycerate kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MNYNKKSIEYIDVKGKKVLVRCDFNVPLNEGKITDENRLVGALPTIKYLMEKGAKIILCSHMGKPKGEPKKELSLLPVAK
RLSEMLNKEVIFADDDNVVGENAKKAVEDMKDGDVVLLQNTRYRKEETKNEEVFSKELASLADVFVNDAFGTAHRAHCST
VGVTNYLKEAACGYLIQKELKFLGNAVEKPERPFVAILGGAKVSDKINVINNLLDKVDTLIIGGGMGYTFLKAQGYTIGN
SLVEEDKVEYSKEMIDKAKEKGVNLLLPIDNVVADKFDKDASPVVTEDQNIGEGYMGLDIGPKTAKIYSDAIKSAKTVVW
NGPMGVFEFKSFANGTIEVAKAMADSDAVTIIGGGDSAAAVNILGFGDKMTHISTGGGASLEFLEGKELPGIAALNDK

Sequences:

>Translated_398_residues
MNYNKKSIEYIDVKGKKVLVRCDFNVPLNEGKITDENRLVGALPTIKYLMEKGAKIILCSHMGKPKGEPKKELSLLPVAK
RLSEMLNKEVIFADDDNVVGENAKKAVEDMKDGDVVLLQNTRYRKEETKNEEVFSKELASLADVFVNDAFGTAHRAHCST
VGVTNYLKEAACGYLIQKELKFLGNAVEKPERPFVAILGGAKVSDKINVINNLLDKVDTLIIGGGMGYTFLKAQGYTIGN
SLVEEDKVEYSKEMIDKAKEKGVNLLLPIDNVVADKFDKDASPVVTEDQNIGEGYMGLDIGPKTAKIYSDAIKSAKTVVW
NGPMGVFEFKSFANGTIEVAKAMADSDAVTIIGGGDSAAAVNILGFGDKMTHISTGGGASLEFLEGKELPGIAALNDK
>Mature_398_residues
MNYNKKSIEYIDVKGKKVLVRCDFNVPLNEGKITDENRLVGALPTIKYLMEKGAKIILCSHMGKPKGEPKKELSLLPVAK
RLSEMLNKEVIFADDDNVVGENAKKAVEDMKDGDVVLLQNTRYRKEETKNEEVFSKELASLADVFVNDAFGTAHRAHCST
VGVTNYLKEAACGYLIQKELKFLGNAVEKPERPFVAILGGAKVSDKINVINNLLDKVDTLIIGGGMGYTFLKAQGYTIGN
SLVEEDKVEYSKEMIDKAKEKGVNLLLPIDNVVADKFDKDASPVVTEDQNIGEGYMGLDIGPKTAKIYSDAIKSAKTVVW
NGPMGVFEFKSFANGTIEVAKAMADSDAVTIIGGGDSAAAVNILGFGDKMTHISTGGGASLEFLEGKELPGIAALNDK

Specific function: Second phase of glycolysis; second step. [C]

COG id: COG0126

COG function: function code G; 3-phosphoglycerate kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate kinase family [H]

Homologues:

Organism=Homo sapiens, GI4505763, Length=417, Percent_Identity=47.9616306954436, Blast_Score=363, Evalue=1e-100,
Organism=Homo sapiens, GI31543397, Length=421, Percent_Identity=45.3681710213777, Blast_Score=347, Evalue=9e-96,
Organism=Escherichia coli, GI1789294, Length=391, Percent_Identity=43.4782608695652, Blast_Score=323, Evalue=1e-89,
Organism=Caenorhabditis elegans, GI17508823, Length=417, Percent_Identity=49.6402877697842, Blast_Score=392, Evalue=1e-109,
Organism=Saccharomyces cerevisiae, GI6319857, Length=416, Percent_Identity=49.0384615384615, Blast_Score=382, Evalue=1e-107,
Organism=Drosophila melanogaster, GI24581203, Length=415, Percent_Identity=46.5060240963855, Blast_Score=352, Evalue=2e-97,
Organism=Drosophila melanogaster, GI17136394, Length=417, Percent_Identity=47.242206235012, Blast_Score=352, Evalue=2e-97,

Paralogues:

None

Copy number: 2990 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1460 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001576
- InterPro:   IPR015901
- InterPro:   IPR015911
- InterPro:   IPR015824 [H]

Pfam domain/function: PF00162 PGK [H]

EC number: =2.7.2.3 [H]

Molecular weight: Translated: 43097; Mature: 43097

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS00111 PGLYCERATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYNKKSIEYIDVKGKKVLVRCDFNVPLNEGKITDENRLVGALPTIKYLMEKGAKIILCS
CCCCCCCEEEEEECCCEEEEEEECCCCCCCCCCCCCCCEEEHHHHHHHHHHCCCEEEEEE
HMGKPKGEPKKELSLLPVAKRLSEMLNKEVIFADDDNVVGENAKKAVEDMKDGDVVLLQN
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHCCCCCEEEEEC
TRYRKEETKNEEVFSKELASLADVFVNDAFGTAHRAHCSTVGVTNYLKEAACGYLIQKEL
CCCCHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHH
KFLGNAVEKPERPFVAILGGAKVSDKINVINNLLDKVDTLIIGGGMGYTFLKAQGYTIGN
HHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHEEEEECCCCEEEEEECCCCCCC
SLVEEDKVEYSKEMIDKAKEKGVNLLLPIDNVVADKFDKDASPVVTEDQNIGEGYMGLDI
HHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHCCCCCCCCEECCCCCCCCEEECCC
GPKTAKIYSDAIKSAKTVVWNGPMGVFEFKSFANGTIEVAKAMADSDAVTIIGGGDSAAA
CCCHHHHHHHHHHCCCEEEECCCCCHHHHHHHCCCHHHHHHHHCCCCCEEEEECCCCCEE
VNILGFGDKMTHISTGGGASLEFLEGKELPGIAALNDK
EEEEECCCCEEEEECCCCCEEEEECCCCCCCEECCCCC
>Mature Secondary Structure
MNYNKKSIEYIDVKGKKVLVRCDFNVPLNEGKITDENRLVGALPTIKYLMEKGAKIILCS
CCCCCCCEEEEEECCCEEEEEEECCCCCCCCCCCCCCCEEEHHHHHHHHHHCCCEEEEEE
HMGKPKGEPKKELSLLPVAKRLSEMLNKEVIFADDDNVVGENAKKAVEDMKDGDVVLLQN
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHCCCCCEEEEEC
TRYRKEETKNEEVFSKELASLADVFVNDAFGTAHRAHCSTVGVTNYLKEAACGYLIQKEL
CCCCHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHH
KFLGNAVEKPERPFVAILGGAKVSDKINVINNLLDKVDTLIIGGGMGYTFLKAQGYTIGN
HHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHEEEEECCCCEEEEEECCCCCCC
SLVEEDKVEYSKEMIDKAKEKGVNLLLPIDNVVADKFDKDASPVVTEDQNIGEGYMGLDI
HHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHCCCCCCCCEECCCCCCCCEEECCC
GPKTAKIYSDAIKSAKTVVWNGPMGVFEFKSFANGTIEVAKAMADSDAVTIIGGGDSAAA
CCCHHHHHHHHHHCCCEEEECCCCCHHHHHHHCCCHHHHHHHHCCCCCEEEEECCCCCEE
VNILGFGDKMTHISTGGGASLEFLEGKELPGIAALNDK
EEEEECCCCEEEEECCCCCEEEEECCCCCCCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA