Click here to switch to the map view.

The map label for this gene is ywoG [H]

Identifier: 226225376

GI number: 226225376

Start: 2882218

End: 2883366

Strand: Reverse

Name: ywoG [H]

Synonym: Lm4b_02799

Alternate gene names: 226225376

Gene position: 2883366-2882218 (Counterclockwise)

Preceding gene: 226225377

Following gene: 226225375

Centisome position: 98.99

GC content: 41.43

Gene sequence:

>1149_bases
TTGGAAAATAAGACAAGACTTTGGACGAAGGACTACGTATTTTTATTGTTAGGCAGTGTACTTTTATATATTGGATTTAT
GGTGTTTATGCCTACGTTGCCGGCTCGCATTATTGAGCTAGGTGGAACGCAAATGGAAGCGAGTTTGGCGGTGGGGCTAT
TCTCCATCGTAGCACTATTAATGCGGGCGATTGCTGGGAGTTGGAATGACAAATTCGGACCGAAAGTACTTATTATCGTG
GGCTTTTTGATTTTAATTTTAACTACAGTGAACTTTTATTGGTCAACGGCGGTGGCGGCCTTACTTATATTACGGCTTTT
TCACGGGGCTGGCTGGGGTATCGGAACAACTTCTATTGCTACAGGCGTTTCTAAACTCGTGCCACCAAGCAGAACGGGAG
AAGGTATTGGTTTTTATGGGCTTACGACTGCACTTGGAATGTCACTTGCGCCGATTATCGCTATTTTAATTATGAATTAT
TTTTCTTTCGATGTTTTAGTGACGTTTTCGCTTGTTTTGATGGTGTTTATTTTAATTTTGATGACACAGGTGAAAATTCC
AAAATCAGAAAAGATTGTACATCAAAAAATGAAATTGTTTGAGAAAACGGCCTTGCTTCCGGCGGGCTTGTGTTTATTAA
TGGCTATTCCGCTTGGTGGGATCCAGACATTTATGATGGTATATGGAACAGAACTGGGGATTTCGACAACGTGGATATAT
TTTATCGGGCAAGCGATTATGGTTCTTGTAAGCCGTTTGTTTGCTGGGCGACTTTATGATACGAAGGGACACCGTTTTGT
TATTATTCCAGGAGCGCTTTCGATGATAATTGGGATATTAATTCTTTCTTTTGCAACTGGTGCAATCAGCTTGTTTATCG
CATCGTTATTCTTCGGGTTAGGTTACGGGATGTCGCAACCGGCGCTTCAAGCACTGGCTGTGGACCGGGCTGCACCGCAC
AATAAAGGTACCGCGAACGGGACTTTTCTTTCGGGAATGGACATTGGAATGGCTGTTGGTAGTTTTGGTTTGAGTATTGT
TGCGACTTACTACAATTATGCTATTATGTATCGCACAGCAATTATTGCACTTGTTGTATTTTTTGCTGTGTATTGGTTTA
CTTTAGGACGAAAAGTGAAAAATAGCTAA

Upstream 100 bases:

>100_bases
TGTGAAAGAATGTTTGCTGGGATTTCTCGCGCAGATTTGGAACAATTCACGGCTATTTTAAAGAACATTTCTACTAATAT
AGAGTAAAGAGGGGTAAATT

Downstream 100 bases:

>100_bases
CATCTTTTGTGAAGTGTTTTTCAAAAAGTAGAAGTGCGAGAATTGCTTTAAATAGCGGTTTCTCGTGCTTTTTTAATGTC
AGAAAGTTTAAACATCACAT

Product: efflux protein

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MENKTRLWTKDYVFLLLGSVLLYIGFMVFMPTLPARIIELGGTQMEASLAVGLFSIVALLMRAIAGSWNDKFGPKVLIIV
GFLILILTTVNFYWSTAVAALLILRLFHGAGWGIGTTSIATGVSKLVPPSRTGEGIGFYGLTTALGMSLAPIIAILIMNY
FSFDVLVTFSLVLMVFILILMTQVKIPKSEKIVHQKMKLFEKTALLPAGLCLLMAIPLGGIQTFMMVYGTELGISTTWIY
FIGQAIMVLVSRLFAGRLYDTKGHRFVIIPGALSMIIGILILSFATGAISLFIASLFFGLGYGMSQPALQALAVDRAAPH
NKGTANGTFLSGMDIGMAVGSFGLSIVATYYNYAIMYRTAIIALVVFFAVYWFTLGRKVKNS

Sequences:

>Translated_382_residues
MENKTRLWTKDYVFLLLGSVLLYIGFMVFMPTLPARIIELGGTQMEASLAVGLFSIVALLMRAIAGSWNDKFGPKVLIIV
GFLILILTTVNFYWSTAVAALLILRLFHGAGWGIGTTSIATGVSKLVPPSRTGEGIGFYGLTTALGMSLAPIIAILIMNY
FSFDVLVTFSLVLMVFILILMTQVKIPKSEKIVHQKMKLFEKTALLPAGLCLLMAIPLGGIQTFMMVYGTELGISTTWIY
FIGQAIMVLVSRLFAGRLYDTKGHRFVIIPGALSMIIGILILSFATGAISLFIASLFFGLGYGMSQPALQALAVDRAAPH
NKGTANGTFLSGMDIGMAVGSFGLSIVATYYNYAIMYRTAIIALVVFFAVYWFTLGRKVKNS
>Mature_382_residues
MENKTRLWTKDYVFLLLGSVLLYIGFMVFMPTLPARIIELGGTQMEASLAVGLFSIVALLMRAIAGSWNDKFGPKVLIIV
GFLILILTTVNFYWSTAVAALLILRLFHGAGWGIGTTSIATGVSKLVPPSRTGEGIGFYGLTTALGMSLAPIIAILIMNY
FSFDVLVTFSLVLMVFILILMTQVKIPKSEKIVHQKMKLFEKTALLPAGLCLLMAIPLGGIQTFMMVYGTELGISTTWIY
FIGQAIMVLVSRLFAGRLYDTKGHRFVIIPGALSMIIGILILSFATGAISLFIASLFFGLGYGMSQPALQALAVDRAAPH
NKGTANGTFLSGMDIGMAVGSFGLSIVATYYNYAIMYRTAIIALVVFFAVYWFTLGRKVKNS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 41494; Mature: 41494

Theoretical pI: Translated: 10.21; Mature: 10.21

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENKTRLWTKDYVFLLLGSVLLYIGFMVFMPTLPARIIELGGTQMEASLAVGLFSIVALL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
MRAIAGSWNDKFGPKVLIIVGFLILILTTVNFYWSTAVAALLILRLFHGAGWGIGTTSIA
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
TGVSKLVPPSRTGEGIGFYGLTTALGMSLAPIIAILIMNYFSFDVLVTFSLVLMVFILIL
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MTQVKIPKSEKIVHQKMKLFEKTALLPAGLCLLMAIPLGGIQTFMMVYGTELGISTTWIY
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHH
FIGQAIMVLVSRLFAGRLYDTKGHRFVIIPGALSMIIGILILSFATGAISLFIASLFFGL
HHHHHHHHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GYGMSQPALQALAVDRAAPHNKGTANGTFLSGMDIGMAVGSFGLSIVATYYNYAIMYRTA
CCCCCHHHHHHHHHHHCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IIALVVFFAVYWFTLGRKVKNS
HHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MENKTRLWTKDYVFLLLGSVLLYIGFMVFMPTLPARIIELGGTQMEASLAVGLFSIVALL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
MRAIAGSWNDKFGPKVLIIVGFLILILTTVNFYWSTAVAALLILRLFHGAGWGIGTTSIA
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
TGVSKLVPPSRTGEGIGFYGLTTALGMSLAPIIAILIMNYFSFDVLVTFSLVLMVFILIL
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MTQVKIPKSEKIVHQKMKLFEKTALLPAGLCLLMAIPLGGIQTFMMVYGTELGISTTWIY
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHH
FIGQAIMVLVSRLFAGRLYDTKGHRFVIIPGALSMIIGILILSFATGAISLFIASLFFGL
HHHHHHHHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GYGMSQPALQALAVDRAAPHNKGTANGTFLSGMDIGMAVGSFGLSIVATYYNYAIMYRTA
CCCCCHHHHHHHHHHHCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IIALVVFFAVYWFTLGRKVKNS
HHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]