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The map label for this gene is kat

Identifier: 226225338

GI number: 226225338

Start: 2843863

End: 2845329

Strand: Reverse

Name: kat

Synonym: Lm4b_02761

Alternate gene names: 226225338

Gene position: 2845329-2843863 (Counterclockwise)

Preceding gene: 226225339

Following gene: 226225337

Centisome position: 97.69

GC content: 40.76

Gene sequence:

>1467_bases
ATGACAGATAGAAAAAATTTAACGACGAATCAAGGTGTGCCAGTTGGTGATAACCAAAATTCGATGACAGCGGGACGTAA
AGGACCAACTTTGATAGAAGATTATGTGCTTATTGAGAAATTGGCACATTTTGATAGAGAACGAGTACCAGAACGGGTTG
TACATGCTCGTGGTGCTGGTGCGCACGGGAAATTTGTCACTAAGAAAAGCATGAAAAAATATACAATGGCTAAATTTTTG
CAAGAAGAAGGAACGGAAACGGAGGTTTTTGCTCGTTTTTCAACAGTAATTCATGGGCAACATTCTCCAGAAACATTACG
TGATCCACGCGGTTTCTCCGTTAAGTTTTATACAGAAGAAGGGAATTATGATTTTGTCGGAAATAATTTGCCGGTATTCT
TCATTCGTGATGCGATTAAGTTTCCGGATGTTATTCATTCCTTGAAGCCTGATCCACGCACAAATATTCAAGATGGCAAC
CGTTACTGGGATTTCTTTAGCCTTACACCGGAAGCTACGACGATGATTATGTACTTATTCAGTGATGAAGGAACGCCGGC
TTCTTACCGGGAAATACGTGGCTCTAGTGTTCATGCGTTCAAATGGATTAACGAAGAAGGCAAAACAGTTTATGTAAAAC
TGCGCTGGATTCCAAAAGCGGGAATAGTGAACCTTTCGACGGAGCAAGCTTCTCAAATTCAAGCAAAAGAATTTAACCAT
GCAAGTCGTGATTTGTACGAAGCAATTGAAAATGGAGACTATCCAGAGTGGGATTTATATGTGCAAGTGTTGGATCCGAA
AGACTTGGATAACTTTGATTTTAATCCATTAGATGCAACAAAAGATTGGTTTGAAGATGTATTTCCTTATGAACACGTAG
GAACAATGACGCTTGACCGCAACCCAGATAATATTTTTGCGGAGACAGAATCGGTTGGTTTTAATCCTGGGGTACTTGTA
CGTGGAATGCTTCCTTCTGAAGACCGTTTATTGCAAGGTCGTTTATTCTCTTACTCAGATACGCAAAGACATCGTGTAGG
GCCAAACTACTTACAACTCCCAATTAACAGTCCGAAAGCGCCTGTCGCGAACAACCAACGTGACGGTCATATGCCGTTTA
AACAACAAACAAGTTCGATTAATTATGAGCCAAATAGTTACGATACAGAACCAAAAGAAAATCCAGCGTTTATCGAGCCA
GAGCAAGAAATCCGTGGTGATATTTCTGGGCGCCTGATTGCAGAAAAACCAAATAACTTTGGCCATGCAAAAGAAGTATG
GGATCGTTATTCAGATGCAGAACGTGCTGCACTCGTGAAAAACATTGTCGATGATTGGTCACAAGTACGTGATGATATTA
AAATCCGCAACTTACGTAATTTCTATCAAGTAGATCCGGAATTCGCTAGTCGAGTGGCTGCGGGAACTGGTGTTAATCTC
GAAGCACATGTAGCAGATTTAAAATAA

Upstream 100 bases:

>100_bases
AGTTGAAGTTTGTCTCTTCCTTCTTTAAAATATAAATAGTATCATTTAATAATTATTACAAATAAAAAATGATATAGAAT
TGTTATGGAGGTATATACAT

Downstream 100 bases:

>100_bases
ATCAAAGCGAAAATCCTTTTTAGGGTTTTCGCTTTTTTATGTTTCACGTGAAACTTTTTGGGCTAGAAGATTGGAGTAAA
GGCATTTTTAACGATATTGC

Product: catalase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 488; Mature: 487

Protein sequence:

>488_residues
MTDRKNLTTNQGVPVGDNQNSMTAGRKGPTLIEDYVLIEKLAHFDRERVPERVVHARGAGAHGKFVTKKSMKKYTMAKFL
QEEGTETEVFARFSTVIHGQHSPETLRDPRGFSVKFYTEEGNYDFVGNNLPVFFIRDAIKFPDVIHSLKPDPRTNIQDGN
RYWDFFSLTPEATTMIMYLFSDEGTPASYREIRGSSVHAFKWINEEGKTVYVKLRWIPKAGIVNLSTEQASQIQAKEFNH
ASRDLYEAIENGDYPEWDLYVQVLDPKDLDNFDFNPLDATKDWFEDVFPYEHVGTMTLDRNPDNIFAETESVGFNPGVLV
RGMLPSEDRLLQGRLFSYSDTQRHRVGPNYLQLPINSPKAPVANNQRDGHMPFKQQTSSINYEPNSYDTEPKENPAFIEP
EQEIRGDISGRLIAEKPNNFGHAKEVWDRYSDAERAALVKNIVDDWSQVRDDIKIRNLRNFYQVDPEFASRVAAGTGVNL
EAHVADLK

Sequences:

>Translated_488_residues
MTDRKNLTTNQGVPVGDNQNSMTAGRKGPTLIEDYVLIEKLAHFDRERVPERVVHARGAGAHGKFVTKKSMKKYTMAKFL
QEEGTETEVFARFSTVIHGQHSPETLRDPRGFSVKFYTEEGNYDFVGNNLPVFFIRDAIKFPDVIHSLKPDPRTNIQDGN
RYWDFFSLTPEATTMIMYLFSDEGTPASYREIRGSSVHAFKWINEEGKTVYVKLRWIPKAGIVNLSTEQASQIQAKEFNH
ASRDLYEAIENGDYPEWDLYVQVLDPKDLDNFDFNPLDATKDWFEDVFPYEHVGTMTLDRNPDNIFAETESVGFNPGVLV
RGMLPSEDRLLQGRLFSYSDTQRHRVGPNYLQLPINSPKAPVANNQRDGHMPFKQQTSSINYEPNSYDTEPKENPAFIEP
EQEIRGDISGRLIAEKPNNFGHAKEVWDRYSDAERAALVKNIVDDWSQVRDDIKIRNLRNFYQVDPEFASRVAAGTGVNL
EAHVADLK
>Mature_487_residues
TDRKNLTTNQGVPVGDNQNSMTAGRKGPTLIEDYVLIEKLAHFDRERVPERVVHARGAGAHGKFVTKKSMKKYTMAKFLQ
EEGTETEVFARFSTVIHGQHSPETLRDPRGFSVKFYTEEGNYDFVGNNLPVFFIRDAIKFPDVIHSLKPDPRTNIQDGNR
YWDFFSLTPEATTMIMYLFSDEGTPASYREIRGSSVHAFKWINEEGKTVYVKLRWIPKAGIVNLSTEQASQIQAKEFNHA
SRDLYEAIENGDYPEWDLYVQVLDPKDLDNFDFNPLDATKDWFEDVFPYEHVGTMTLDRNPDNIFAETESVGFNPGVLVR
GMLPSEDRLLQGRLFSYSDTQRHRVGPNYLQLPINSPKAPVANNQRDGHMPFKQQTSSINYEPNSYDTEPKENPAFIEPE
QEIRGDISGRLIAEKPNNFGHAKEVWDRYSDAERAALVKNIVDDWSQVRDDIKIRNLRNFYQVDPEFASRVAAGTGVNLE
AHVADLK

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=471, Percent_Identity=43.0997876857749, Blast_Score=402, Evalue=1e-112,
Organism=Escherichia coli, GI48994891, Length=490, Percent_Identity=44.4897959183673, Blast_Score=397, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI71998444, Length=480, Percent_Identity=42.0833333333333, Blast_Score=409, Evalue=1e-114,
Organism=Caenorhabditis elegans, GI25147792, Length=468, Percent_Identity=41.4529914529915, Blast_Score=391, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI25151141, Length=468, Percent_Identity=41.4529914529915, Blast_Score=391, Evalue=1e-109,
Organism=Saccharomyces cerevisiae, GI6320462, Length=370, Percent_Identity=43.5135135135135, Blast_Score=317, Evalue=2e-87,
Organism=Saccharomyces cerevisiae, GI6321525, Length=513, Percent_Identity=35.4775828460039, Blast_Score=305, Evalue=1e-83,
Organism=Drosophila melanogaster, GI17981717, Length=468, Percent_Identity=42.7350427350427, Blast_Score=393, Evalue=1e-109,
Organism=Drosophila melanogaster, GI19920968, Length=471, Percent_Identity=38.0042462845011, Blast_Score=365, Evalue=1e-101,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 55829; Mature: 55698

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: PS00437 CATALASE_1 ; PS00438 CATALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDRKNLTTNQGVPVGDNQNSMTAGRKGPTLIEDYVLIEKLAHFDRERVPERVVHARGAG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AHGKFVTKKSMKKYTMAKFLQEEGTETEVFARFSTVIHGQHSPETLRDPRGFSVKFYTEE
CCCCEECHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHCCCCCCEEEEEEEC
GNYDFVGNNLPVFFIRDAIKFPDVIHSLKPDPRTNIQDGNRYWDFFSLTPEATTMIMYLF
CCEEEECCCCCEEEEECHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCEEEEEEEE
SDEGTPASYREIRGSSVHAFKWINEEGKTVYVKLRWIPKAGIVNLSTEQASQIQAKEFNH
ECCCCCHHHHHHCCCCEEEEEEECCCCCEEEEEEEEECCCCEEECCHHHHHHHHHHHHCH
ASRDLYEAIENGDYPEWDLYVQVLDPKDLDNFDFNPLDATKDWFEDVFPYEHVGTMTLDR
HHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCCHHHHHHCCCHHHCCEEEECC
NPDNIFAETESVGFNPGVLVRGMLPSEDRLLQGRLFSYSDTQRHRVGPNYLQLPINSPKA
CCCCEEEECCCCCCCCCEEEEECCCCCCHHHHCEEECCCCCHHHCCCCCEEEEECCCCCC
PVANNQRDGHMPFKQQTSSINYEPNSYDTEPKENPAFIEPEQEIRGDISGRLIAEKPNNF
CCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCEEEEECCCCC
GHAKEVWDRYSDAERAALVKNIVDDWSQVRDDIKIRNLRNFYQVDPEFASRVAAGTGVNL
CCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCE
EAHVADLK
EEECCCCC
>Mature Secondary Structure 
TDRKNLTTNQGVPVGDNQNSMTAGRKGPTLIEDYVLIEKLAHFDRERVPERVVHARGAG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AHGKFVTKKSMKKYTMAKFLQEEGTETEVFARFSTVIHGQHSPETLRDPRGFSVKFYTEE
CCCCEECHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHCCCCCCEEEEEEEC
GNYDFVGNNLPVFFIRDAIKFPDVIHSLKPDPRTNIQDGNRYWDFFSLTPEATTMIMYLF
CCEEEECCCCCEEEEECHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCEEEEEEEE
SDEGTPASYREIRGSSVHAFKWINEEGKTVYVKLRWIPKAGIVNLSTEQASQIQAKEFNH
ECCCCCHHHHHHCCCCEEEEEEECCCCCEEEEEEEEECCCCEEECCHHHHHHHHHHHHCH
ASRDLYEAIENGDYPEWDLYVQVLDPKDLDNFDFNPLDATKDWFEDVFPYEHVGTMTLDR
HHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCCHHHHHHCCCHHHCCEEEECC
NPDNIFAETESVGFNPGVLVRGMLPSEDRLLQGRLFSYSDTQRHRVGPNYLQLPINSPKA
CCCCEEEECCCCCCCCCEEEEECCCCCCHHHHCEEECCCCCHHHCCCCCEEEEECCCCCC
PVANNQRDGHMPFKQQTSSINYEPNSYDTEPKENPAFIEPEQEIRGDISGRLIAEKPNNF
CCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCEEEEECCCCC
GHAKEVWDRYSDAERAALVKNIVDDWSQVRDDIKIRNLRNFYQVDPEFASRVAAGTGVNL
CCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCE
EAHVADLK
EEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]