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The map label for this gene is licR [H]

Identifier: 226225337

GI number: 226225337

Start: 2841736

End: 2843652

Strand: Reverse

Name: licR [H]

Synonym: Lm4b_02760

Alternate gene names: 226225337

Gene position: 2843652-2841736 (Counterclockwise)

Preceding gene: 226225338

Following gene: 226225336

Centisome position: 97.63

GC content: 36.1

Gene sequence:

>1917_bases
GTGAGTGCTTCAAAATTATCATTACCTAGATGGAAACAAATAGTTCATATGCTTTATTTGAAGATGGAGTTTATTAGCGG
TGGAGAATTAGGGGAGGCATTAGCTGTTAACCCTCGGACAATTAGAAATGATATTAAAGTAATTAATCAAATACTGATGA
TAGGCGGAAACAGAATCGAATCGCTTCCTGGTGTAGGATATCGTCTGGTCATTGGTGATGAAAAAGCGCTGCGTGAAGCT
CTTTTGGACGATTCGATAGGAAGAGCTAATATGAATATTGTACCGATGTTTGCAGAGGATAGAGCAGATTATATTATTCG
ATATTTATTACTCAAAAATGACTATGTAAAGCTGGAGACGTTGTCAGAAGAGCTTTTTGTTAGTAAGTCTACGATAAACT
TGGATATTTTAGAAGTGAAACGAAAACTCAAAGAAAATGAGTTGAAAGTGGAAAAACGGGCTGGCTATGGCATTAGAATT
ACTGGTGCAGAACTTGCTATCCGATTTTGCTTTTCAAGATATTTGTTAGTGGAATCTACAAGCCCGCTTATTACAGAAAC
AGAAATAAATTTTTTTGGAGAAGTTAATTTGGAAATGATGGAGCAGATTGTCGTTTCTAATATAGCGAAATATAATATTC
ACATGACGGACATTTCAGTTAAAAATTTGATTATTCATATCGCAATTGCTGTATGTCGTGTAAAAGATAATTGTTATGTA
CCTGCAACAGATTTGGAGGATATTGAATTTAGTATGCCGGAATTAAGGGCGGCTCAAGGTATTATAAAAGAAATAGATCT
TTCAGAAGGAATTCGTTTCCCGGAAAGTGAGACTGCCTATCTGCTGCTACACCTTAGTTCGAAAAACAGAAAAAGTGACT
TTAATAATTACCGAGAATATATCATCGTGGATAAGATGTTAGAAAAGATTAAAGAGCTGTACGGTTATGATTTTAAGCAA
GACCAGAAAATGATTTCCAATATCGCTTTGCATTTAAAGCCAGCTATTAACAGAATTAAATTTAATATGAATATACAAAA
CCCGTATTTAAAAAATCTAAAAGCTAATTATCCACTAGCTTTTGAATTAGGGTTGGTTGCTAAAGAAGTCCTTGAGCAGG
AGTTAAAAACAAATGTAGACGAAGCGGAAGTAGGATATTTGGCTATTCACTTTTTGTATGGCTTAGATAAGGAAATAGGG
TCTGAGAAGCAAAAAGTATTGATTGTTTGTGCTTCTGGTTTAGGGACGTCGCAACTTTTGGAATCTAAAGTACGAAAAGA
GTTTGAGAATACGCTTGAAATAGTCGGCGTGTACTCATTTAAAGAATATGAGCAGAGTGGAACGGCATGTGACTTTGTTA
TCTCTACAGTACCACTGCGAATGAAGTTACATCCATTTATTCAAGTATCGCCATTTTTGACAAAGGCGGATATTCGTAAT
ATCACTGCGTTAATGAAGCAAGATGAGACGAAGAACCAATTTGAAGTGGACAAGGTTTTTAAGGAATCGTTATTCTTAAT
TAGTGATAAAAAGGACAAAGAGCAAGTTCTGGTAGATTTAGCGAGTCTTTTGCTGGAAAATAATATTGTTGGCGAGGACT
ATTTACCATCACTTTTTGAGCGCGAAGAAATTGTGCCGACTTATTTAGGTAATGGACTTGCGGCACCACACCCAATTGAA
GCAAACGTCCAAGAAACAGCTATTGGAGTATGTATTTTTACTGGCGGTGGGGTAAAGTGGAATGAGGAAGATCAGGCACA
AGTGATTTTCATGTTAGCGGTAAAAAACAAGCAACAACAGCAGCTTGCGACGGTGTATGAGCTTATTAGCAATTTAGTAG
AAAGTCCAAAAGCAATGGGAGAGCTAAAACGTGTGACAAGTTTTGAAGAATTTATGCGTGTGTTACAAACGATATAA

Upstream 100 bases:

>100_bases
AATACTTGCTACTATTTCTGGAAGACTTGTCGTTATCAGGTGATAGGCTTATAATCAAGATGAAATAGCTTAAATTAATT
GTCGTGAGGAGTGGAGCTGC

Downstream 100 bases:

>100_bases
CCAAAAGGTTCGTTAGACTTTCTTAGAGAGAAAAGTTAACGGGCCTTTTTTTATTTCCGCATGTAAAATACAGATGCGGA
AAAAGACTAGATTTATTTAA

Product: licABCH operon regulator

Products: NA

Alternate protein names: Putative phosphotransferase enzyme IIB component; Putative PTS system EIIB component; Putative phosphotransferase enzyme IIA component; Putative PTS system EIIA component [H]

Number of amino acids: Translated: 638; Mature: 637

Protein sequence:

>638_residues
MSASKLSLPRWKQIVHMLYLKMEFISGGELGEALAVNPRTIRNDIKVINQILMIGGNRIESLPGVGYRLVIGDEKALREA
LLDDSIGRANMNIVPMFAEDRADYIIRYLLLKNDYVKLETLSEELFVSKSTINLDILEVKRKLKENELKVEKRAGYGIRI
TGAELAIRFCFSRYLLVESTSPLITETEINFFGEVNLEMMEQIVVSNIAKYNIHMTDISVKNLIIHIAIAVCRVKDNCYV
PATDLEDIEFSMPELRAAQGIIKEIDLSEGIRFPESETAYLLLHLSSKNRKSDFNNYREYIIVDKMLEKIKELYGYDFKQ
DQKMISNIALHLKPAINRIKFNMNIQNPYLKNLKANYPLAFELGLVAKEVLEQELKTNVDEAEVGYLAIHFLYGLDKEIG
SEKQKVLIVCASGLGTSQLLESKVRKEFENTLEIVGVYSFKEYEQSGTACDFVISTVPLRMKLHPFIQVSPFLTKADIRN
ITALMKQDETKNQFEVDKVFKESLFLISDKKDKEQVLVDLASLLLENNIVGEDYLPSLFEREEIVPTYLGNGLAAPHPIE
ANVQETAIGVCIFTGGGVKWNEEDQAQVIFMLAVKNKQQQQLATVYELISNLVESPKAMGELKRVTSFEEFMRVLQTI

Sequences:

>Translated_638_residues
MSASKLSLPRWKQIVHMLYLKMEFISGGELGEALAVNPRTIRNDIKVINQILMIGGNRIESLPGVGYRLVIGDEKALREA
LLDDSIGRANMNIVPMFAEDRADYIIRYLLLKNDYVKLETLSEELFVSKSTINLDILEVKRKLKENELKVEKRAGYGIRI
TGAELAIRFCFSRYLLVESTSPLITETEINFFGEVNLEMMEQIVVSNIAKYNIHMTDISVKNLIIHIAIAVCRVKDNCYV
PATDLEDIEFSMPELRAAQGIIKEIDLSEGIRFPESETAYLLLHLSSKNRKSDFNNYREYIIVDKMLEKIKELYGYDFKQ
DQKMISNIALHLKPAINRIKFNMNIQNPYLKNLKANYPLAFELGLVAKEVLEQELKTNVDEAEVGYLAIHFLYGLDKEIG
SEKQKVLIVCASGLGTSQLLESKVRKEFENTLEIVGVYSFKEYEQSGTACDFVISTVPLRMKLHPFIQVSPFLTKADIRN
ITALMKQDETKNQFEVDKVFKESLFLISDKKDKEQVLVDLASLLLENNIVGEDYLPSLFEREEIVPTYLGNGLAAPHPIE
ANVQETAIGVCIFTGGGVKWNEEDQAQVIFMLAVKNKQQQQLATVYELISNLVESPKAMGELKRVTSFEEFMRVLQTI
>Mature_637_residues
SASKLSLPRWKQIVHMLYLKMEFISGGELGEALAVNPRTIRNDIKVINQILMIGGNRIESLPGVGYRLVIGDEKALREAL
LDDSIGRANMNIVPMFAEDRADYIIRYLLLKNDYVKLETLSEELFVSKSTINLDILEVKRKLKENELKVEKRAGYGIRIT
GAELAIRFCFSRYLLVESTSPLITETEINFFGEVNLEMMEQIVVSNIAKYNIHMTDISVKNLIIHIAIAVCRVKDNCYVP
ATDLEDIEFSMPELRAAQGIIKEIDLSEGIRFPESETAYLLLHLSSKNRKSDFNNYREYIIVDKMLEKIKELYGYDFKQD
QKMISNIALHLKPAINRIKFNMNIQNPYLKNLKANYPLAFELGLVAKEVLEQELKTNVDEAEVGYLAIHFLYGLDKEIGS
EKQKVLIVCASGLGTSQLLESKVRKEFENTLEIVGVYSFKEYEQSGTACDFVISTVPLRMKLHPFIQVSPFLTKADIRNI
TALMKQDETKNQFEVDKVFKESLFLISDKKDKEQVLVDLASLLLENNIVGEDYLPSLFEREEIVPTYLGNGLAAPHPIEA
NVQETAIGVCIFTGGGVKWNEEDQAQVIFMLAVKNKQQQQLATVYELISNLVESPKAMGELKRVTSFEEFMRVLQTI

Specific function: Positive regulator of the licABCH operon [H]

COG id: COG3711

COG function: function code K; Transcriptional antiterminator

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIB type-2 domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013196
- InterPro:   IPR007737
- InterPro:   IPR011608
- InterPro:   IPR016152
- InterPro:   IPR002178
- InterPro:   IPR013011
- InterPro:   IPR003501
- InterPro:   IPR011991 [H]

Pfam domain/function: PF08279 HTH_11; PF05043 Mga; PF00874 PRD; PF00359 PTS_EIIA_2; PF02302 PTS_IIB [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 72620; Mature: 72489

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS51094 PTS_EIIA_TYPE_2 ; PS51099 PTS_EIIB_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSASKLSLPRWKQIVHMLYLKMEFISGGELGEALAVNPRTIRNDIKVINQILMIGGNRIE
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHHHHHHHHHCCCHHC
SLPGVGYRLVIGDEKALREALLDDSIGRANMNIVPMFAEDRADYIIRYLLLKNDYVKLET
CCCCCCEEEEECCHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCEEEEE
LSEELFVSKSTINLDILEVKRKLKENELKVEKRAGYGIRITGAELAIRFCFSRYLLVEST
HHHHHHEECCCCCCHHHHHHHHHHHHHCCHHHCCCCCEEEEHHHHHHHHHHHHHHEEECC
SPLITETEINFFGEVNLEMMEQIVVSNIAKYNIHMTDISVKNLIIHIAIAVCRVKDNCYV
CCCEEEECCCEEECCCHHHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHHHEECCCCEE
PATDLEDIEFSMPELRAAQGIIKEIDLSEGIRFPESETAYLLLHLSSKNRKSDFNNYREY
CCCCCCCCCCCCHHHHHHHHHHHHCCHHCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHH
IIVDKMLEKIKELYGYDFKQDQKMISNIALHLKPAINRIKFNMNIQNPYLKNLKANYPLA
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHEECCCEEEEEEEEECCHHHHCCCCCCCEE
FELGLVAKEVLEQELKTNVDEAEVGYLAIHFLYGLDKEIGSEKQKVLIVCASGLGTSQLL
EHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHCCCCCEEEEEEECCCCHHHHH
ESKVRKEFENTLEIVGVYSFKEYEQSGTACDFVISTVPLRMKLHPFIQVSPFLTKADIRN
HHHHHHHHHHHHHHEEEEHHHHHHCCCCEEEHHHHCCCEEEEECCCEEECCCHHHHHHHH
ITALMKQDETKNQFEVDKVFKESLFLISDKKDKEQVLVDLASLLLENNIVGEDYLPSLFE
HHHHHHCCCCCCHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHH
REEIVPTYLGNGLAAPHPIEANVQETAIGVCIFTGGGVKWNEEDQAQVIFMLAVKNKQQQ
HHCCCHHHHCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCEEEEEEEECCCHHH
QLATVYELISNLVESPKAMGELKRVTSFEEFMRVLQTI
HHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SASKLSLPRWKQIVHMLYLKMEFISGGELGEALAVNPRTIRNDIKVINQILMIGGNRIE
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHHHHHHHHHCCCHHC
SLPGVGYRLVIGDEKALREALLDDSIGRANMNIVPMFAEDRADYIIRYLLLKNDYVKLET
CCCCCCEEEEECCHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCEEEEE
LSEELFVSKSTINLDILEVKRKLKENELKVEKRAGYGIRITGAELAIRFCFSRYLLVEST
HHHHHHEECCCCCCHHHHHHHHHHHHHCCHHHCCCCCEEEEHHHHHHHHHHHHHHEEECC
SPLITETEINFFGEVNLEMMEQIVVSNIAKYNIHMTDISVKNLIIHIAIAVCRVKDNCYV
CCCEEEECCCEEECCCHHHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHHHEECCCCEE
PATDLEDIEFSMPELRAAQGIIKEIDLSEGIRFPESETAYLLLHLSSKNRKSDFNNYREY
CCCCCCCCCCCCHHHHHHHHHHHHCCHHCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHH
IIVDKMLEKIKELYGYDFKQDQKMISNIALHLKPAINRIKFNMNIQNPYLKNLKANYPLA
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHEECCCEEEEEEEEECCHHHHCCCCCCCEE
FELGLVAKEVLEQELKTNVDEAEVGYLAIHFLYGLDKEIGSEKQKVLIVCASGLGTSQLL
EHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHCCCCCEEEEEEECCCCHHHHH
ESKVRKEFENTLEIVGVYSFKEYEQSGTACDFVISTVPLRMKLHPFIQVSPFLTKADIRN
HHHHHHHHHHHHHHEEEEHHHHHHCCCCEEEHHHHCCCEEEEECCCEEECCCHHHHHHHH
ITALMKQDETKNQFEVDKVFKESLFLISDKKDKEQVLVDLASLLLENNIVGEDYLPSLFE
HHHHHHCCCCCCHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHH
REEIVPTYLGNGLAAPHPIEANVQETAIGVCIFTGGGVKWNEEDQAQVIFMLAVKNKQQQ
HHCCCHHHHCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCEEEEEEEECCCHHH
QLATVYELISNLVESPKAMGELKRVTSFEEFMRVLQTI
HHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8990303; 8969509; 9384377; 10438772 [H]