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The map label for this gene is dhaL [H]

Identifier: 226225247

GI number: 226225247

Start: 2742781

End: 2743377

Strand: Direct

Name: dhaL [H]

Synonym: Lm4b_02669

Alternate gene names: 226225247

Gene position: 2742781-2743377 (Clockwise)

Preceding gene: 226225246

Following gene: 226225248

Centisome position: 94.17

GC content: 44.39

Gene sequence:

>597_bases
ATGACTTATGATAAAGATTGGGCGTTACGCTGGTTAAATGACTTCGGCGAACGCGTACAAGAAAACAAACAATTATTAAG
TGATCTCGACCAAGCGATTGGCGACGGAGACCACGGTATCAATATGGCTCGCGGACTCGGCGAACTCAAAAAAGCTTTCA
CAGAAAAAGAACCCGCTGATTTAAAAGATGTATTTAAAACCGCTGGGATGACGATGGTCAGCAAGGTCGGCGGCGCATCT
GGACCACTTTATGGAACAGCCTTTTTAAACATGAGTAAAGCGGTAGATTCAGAAACAATTGACGCGGAAGGCTTAACCAA
AGTGCTTGAAGCAGGACTTGAAGGGATTGAAAAACGCGGTAAATCCCATGCTGGCGAGAAAACAATGATTGATGTTTGGG
AACCGGTTGTAAATGCGATTCATCAGGAAGATTTAACAGATGATGTTGTTGATGCCGCTTTACAAAAAACAAAAGATTTA
AAAGCTACTAAAGGTCGCGCGAGTTATCTTGGTGAGCGGTCAATTGGTCACCTTGACCCTGGCGCTTACTCTTCTGCCCT
GCTATTTCACGCAATGCTTCAAACGGAGGTGAGCTAA

Upstream 100 bases:

>100_bases
ATCCTTAACCATTTTGAAATTAGAGGACGAAAAATGGGTTGATATGTTGAAACTCCCAGTGGACACAATTGCATGGTAAT
AAAATTTGGAGGAATGAATC

Downstream 100 bases:

>100_bases
CCCATGGCTAAACCTTATGGCGTTGTTATCATTTCTCATTCCAAAGATGTGGCAAAAGGCGTCCATGATATTATTAAAGA
AATTGCCCCAGACGTCTCTA

Product: hypothetical dihydroxyacetone kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 198; Mature: 197

Protein sequence:

>198_residues
MTYDKDWALRWLNDFGERVQENKQLLSDLDQAIGDGDHGINMARGLGELKKAFTEKEPADLKDVFKTAGMTMVSKVGGAS
GPLYGTAFLNMSKAVDSETIDAEGLTKVLEAGLEGIEKRGKSHAGEKTMIDVWEPVVNAIHQEDLTDDVVDAALQKTKDL
KATKGRASYLGERSIGHLDPGAYSSALLFHAMLQTEVS

Sequences:

>Translated_198_residues
MTYDKDWALRWLNDFGERVQENKQLLSDLDQAIGDGDHGINMARGLGELKKAFTEKEPADLKDVFKTAGMTMVSKVGGAS
GPLYGTAFLNMSKAVDSETIDAEGLTKVLEAGLEGIEKRGKSHAGEKTMIDVWEPVVNAIHQEDLTDDVVDAALQKTKDL
KATKGRASYLGERSIGHLDPGAYSSALLFHAMLQTEVS
>Mature_197_residues
TYDKDWALRWLNDFGERVQENKQLLSDLDQAIGDGDHGINMARGLGELKKAFTEKEPADLKDVFKTAGMTMVSKVGGASG
PLYGTAFLNMSKAVDSETIDAEGLTKVLEAGLEGIEKRGKSHAGEKTMIDVWEPVVNAIHQEDLTDDVVDAALQKTKDLK
ATKGRASYLGERSIGHLDPGAYSSALLFHAMLQTEVS

Specific function: ADP-binding subunit of the dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone [H]

COG id: COG2376

COG function: function code G; Dihydroxyacetone kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DhaL domain [H]

Homologues:

Organism=Homo sapiens, GI20149621, Length=168, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1787449, Length=208, Percent_Identity=39.4230769230769, Blast_Score=146, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6323570, Length=196, Percent_Identity=31.1224489795918, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004007
- InterPro:   IPR012737 [H]

Pfam domain/function: PF02734 Dak2 [H]

EC number: NA

Molecular weight: Translated: 21513; Mature: 21382

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYDKDWALRWLNDFGERVQENKQLLSDLDQAIGDGDHGINMARGLGELKKAFTEKEPAD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCH
LKDVFKTAGMTMVSKVGGASGPLYGTAFLNMSKAVDSETIDAEGLTKVLEAGLEGIEKRG
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHCCHHHHHHHHHHHHHHHHHHH
KSHAGEKTMIDVWEPVVNAIHQEDLTDDVVDAALQKTKDLKATKGRASYLGERSIGHLDP
HCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCC
GAYSSALLFHAMLQTEVS
CHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TYDKDWALRWLNDFGERVQENKQLLSDLDQAIGDGDHGINMARGLGELKKAFTEKEPAD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCH
LKDVFKTAGMTMVSKVGGASGPLYGTAFLNMSKAVDSETIDAEGLTKVLEAGLEGIEKRG
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHCCHHHHHHHHHHHHHHHHHHH
KSHAGEKTMIDVWEPVVNAIHQEDLTDDVVDAALQKTKDLKATKGRASYLGERSIGHLDP
HCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCC
GAYSSALLFHAMLQTEVS
CHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]