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The map label for this gene is mtlR [H]

Identifier: 226225219

GI number: 226225219

Start: 2712153

End: 2714222

Strand: Reverse

Name: mtlR [H]

Synonym: Lm4b_02641

Alternate gene names: 226225219

Gene position: 2714222-2712153 (Counterclockwise)

Preceding gene: 226225220

Following gene: 226225218

Centisome position: 93.19

GC content: 39.42

Gene sequence:

>2070_bases
ATGTATTTGGATGAGAGAAGTAATTCACTTTTAAAAGAACTCTTACGACATCCTGACACATCGAGTACGAACTTACAAGC
AAAATTCGGTTTAACTCGAAGACAAGTCGACTATAGTTTCCAAAAAATTAATAATTGGCTAGAAGAACAGACTTACCCGA
AGATTCATCGTGCTGCAAATGGTCGATTTATCGTAGAACCTGACCTGTTTCAAATCATTGGTGAGGAAGATGGCGAAAAA
ACAGATTGGTACATCCCGTCAGAAAAGGAACGCGCTAGTCTAATCATCCTCATGTTAACAACAGGAAGTGAAGAGTTATC
CCTTAATCACTTTATAAGCGAGCTGGAGGTGAGCAAGAACACCGTATTACGAGACTTGAAGCTGGTACAAAAGACACTTG
AAAAATTCAACCTTGAAGTTAAATATTCGCGGATGCGTGGCTATTTAATTGACGGAGACGAGTGGAATCAGCGGACGGCA
CTCATTTATGCGGCAGAACACATCATAGAAAGTTTTGGCGGCGAAGAGTATTTACAGGATTTCATGCAAGTGGACGAAGC
GAGAATTAAAGAGCTTCGGGAAAAATTGGAACAAGTTGAGCATCATCTGAATTTGCATTTTATTGACAATAAAATGCAAA
TACTGCCTTACATTTTAGAAGCTGTTTTTCGGCGGATGAAGAAGGGGCAAACAATTACGACATCTTTCCTGATTGACTAC
AATGAATTGTCAGATACTCGGGAATACGGAGCAGCAGAGATTTTTATTGAAGAAGAGCCGAATATGCCAGAAGCAGAGCG
AATGTACATCACATTACAACTTTTAACTTCCAATGTACTTCCGAAACAATATTTGAAATCGGAGGAAACGCACAAGTTAA
GACTGGCGCTGGAACAAGTTCTAAGCGAATTTGAGAAAAAGGCTTGTATTCAACTAGTAGACAAAGAATCGTTACTTGAA
AAATTATTTGCACACATTAAACCTGCGTATTATCGAATTAAGTATCATCTTACAACAGATTACAGCATTTTAGACAAGAT
TGATCAAGAATTCCAAGCCGTGCATTACATCGTGAAAGAGTCGTTAGCACCATTAGAACGTTTTATTGGTAGCAAAGTTC
CTGAAAATGAAAGTATATTTATTACCCTTTTCATTGGAGGGCATTTAATCGAATCCACAGAGAAATTACAAACGAGACTA
AAAGCAGTTGTGGTTTGTCCGAACGGATTGTCGATTTCGAGATTGATGGAAAAAACATTACGAAGCCTTTTTCCGGAAAT
ATTTTTCTATCAAGCGATGTCGATTCGAGAATTTGAACAAACAAAGTTAGGTTATGACATTGTATTTTCCGCAGTGCCAC
TTTCGACCGACAAGAAATTTTTCCTTATCAACCAACTGATGGATGGGAAAGAACGCCTGGAGCTTAGACGCCGGGTGATG
CGAGCGGTTTACTTAGTGGATGAGGTGAATATCAGCGTCGATCAATTAATGAAAACTATTTCCAAATTTGCTGATATTAA
AGATGCTGCCCGTCTTGAAAAAGTGCTAGCAGATTATTTAATGCCAGTTCCAGAAGAAAACACATCCAAACACGAAGGCA
AAAGCACACTCGCAGATCTACTCGAAGTAACGCGAATCACACGTAAGAAATCAGTGAAAGATTGGCATGAGGCAATTTAT
CATGCGGCTTTACCGTTACTTTCGGCGGGAGTGGTGGAACCAGCCTACGTGGAAGAAATGAAACGGCAATATCCGGCACC
GATTATGAACATCATTCTCCGTAATACAATAGCTATCCCTCATGCTGAAACGGAAAAAGGAGTAAATAGCCTCGGAATGA
GCTTGCTTTATCTAGAAGAAGGCCTGCCACTTGAAGGCGGTAAAGAGCTACATTTTATCGTTGTCATTGCAGCCATAGAT
AAAAACGCTCACTTCACAGCTTTACTACAATTGATGGAATTATCGGAGAACAAAAAAGAACTGAAAAAACTTGCGGATGC
TGCGAACACAGAAGAAATGCACCAAATAATTAAAAACTTCACGGACTTGGAAACAAAAAAGACAATGTAG

Upstream 100 bases:

>100_bases
AGCCCAATGATGTACATTCTTTCCGCAAGTTATTGGGATGAAAGCGTGTACATTTTTATTAGATTTAGATTTATAATTAA
AACGAACAGGAGGGAACGAC

Downstream 100 bases:

>100_bases
AGAAGTCAGAAAGAATTACAGGAGGATTTCGTAATGGATTTAGTACAATTTTTGAAAAAAGGAATGGTTTGGGTTCAATC
GGATATCGAGAAACAAGAGG

Product: transcriptional antiterminator (BglG family)

Products: NA

Alternate protein names: Mannitol operon transcriptional activator; Mtl operon transcriptional activator; Putative phosphotransferase enzyme IIB component; Putative PTS system EIIB component; Putative phosphotransferase enzyme IIA component; Putative PTS system EIIA component [H]

Number of amino acids: Translated: 689; Mature: 689

Protein sequence:

>689_residues
MYLDERSNSLLKELLRHPDTSSTNLQAKFGLTRRQVDYSFQKINNWLEEQTYPKIHRAANGRFIVEPDLFQIIGEEDGEK
TDWYIPSEKERASLIILMLTTGSEELSLNHFISELEVSKNTVLRDLKLVQKTLEKFNLEVKYSRMRGYLIDGDEWNQRTA
LIYAAEHIIESFGGEEYLQDFMQVDEARIKELREKLEQVEHHLNLHFIDNKMQILPYILEAVFRRMKKGQTITTSFLIDY
NELSDTREYGAAEIFIEEEPNMPEAERMYITLQLLTSNVLPKQYLKSEETHKLRLALEQVLSEFEKKACIQLVDKESLLE
KLFAHIKPAYYRIKYHLTTDYSILDKIDQEFQAVHYIVKESLAPLERFIGSKVPENESIFITLFIGGHLIESTEKLQTRL
KAVVVCPNGLSISRLMEKTLRSLFPEIFFYQAMSIREFEQTKLGYDIVFSAVPLSTDKKFFLINQLMDGKERLELRRRVM
RAVYLVDEVNISVDQLMKTISKFADIKDAARLEKVLADYLMPVPEENTSKHEGKSTLADLLEVTRITRKKSVKDWHEAIY
HAALPLLSAGVVEPAYVEEMKRQYPAPIMNIILRNTIAIPHAETEKGVNSLGMSLLYLEEGLPLEGGKELHFIVVIAAID
KNAHFTALLQLMELSENKKELKKLADAANTEEMHQIIKNFTDLETKKTM

Sequences:

>Translated_689_residues
MYLDERSNSLLKELLRHPDTSSTNLQAKFGLTRRQVDYSFQKINNWLEEQTYPKIHRAANGRFIVEPDLFQIIGEEDGEK
TDWYIPSEKERASLIILMLTTGSEELSLNHFISELEVSKNTVLRDLKLVQKTLEKFNLEVKYSRMRGYLIDGDEWNQRTA
LIYAAEHIIESFGGEEYLQDFMQVDEARIKELREKLEQVEHHLNLHFIDNKMQILPYILEAVFRRMKKGQTITTSFLIDY
NELSDTREYGAAEIFIEEEPNMPEAERMYITLQLLTSNVLPKQYLKSEETHKLRLALEQVLSEFEKKACIQLVDKESLLE
KLFAHIKPAYYRIKYHLTTDYSILDKIDQEFQAVHYIVKESLAPLERFIGSKVPENESIFITLFIGGHLIESTEKLQTRL
KAVVVCPNGLSISRLMEKTLRSLFPEIFFYQAMSIREFEQTKLGYDIVFSAVPLSTDKKFFLINQLMDGKERLELRRRVM
RAVYLVDEVNISVDQLMKTISKFADIKDAARLEKVLADYLMPVPEENTSKHEGKSTLADLLEVTRITRKKSVKDWHEAIY
HAALPLLSAGVVEPAYVEEMKRQYPAPIMNIILRNTIAIPHAETEKGVNSLGMSLLYLEEGLPLEGGKELHFIVVIAAID
KNAHFTALLQLMELSENKKELKKLADAANTEEMHQIIKNFTDLETKKTM
>Mature_689_residues
MYLDERSNSLLKELLRHPDTSSTNLQAKFGLTRRQVDYSFQKINNWLEEQTYPKIHRAANGRFIVEPDLFQIIGEEDGEK
TDWYIPSEKERASLIILMLTTGSEELSLNHFISELEVSKNTVLRDLKLVQKTLEKFNLEVKYSRMRGYLIDGDEWNQRTA
LIYAAEHIIESFGGEEYLQDFMQVDEARIKELREKLEQVEHHLNLHFIDNKMQILPYILEAVFRRMKKGQTITTSFLIDY
NELSDTREYGAAEIFIEEEPNMPEAERMYITLQLLTSNVLPKQYLKSEETHKLRLALEQVLSEFEKKACIQLVDKESLLE
KLFAHIKPAYYRIKYHLTTDYSILDKIDQEFQAVHYIVKESLAPLERFIGSKVPENESIFITLFIGGHLIESTEKLQTRL
KAVVVCPNGLSISRLMEKTLRSLFPEIFFYQAMSIREFEQTKLGYDIVFSAVPLSTDKKFFLINQLMDGKERLELRRRVM
RAVYLVDEVNISVDQLMKTISKFADIKDAARLEKVLADYLMPVPEENTSKHEGKSTLADLLEVTRITRKKSVKDWHEAIY
HAALPLLSAGVVEPAYVEEMKRQYPAPIMNIILRNTIAIPHAETEKGVNSLGMSLLYLEEGLPLEGGKELHFIVVIAAID
KNAHFTALLQLMELSENKKELKKLADAANTEEMHQIIKNFTDLETKKTM

Specific function: Positively regulates the expression of the mtlAFD operon involved in the uptake and catabolism of mannitol [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIB type-2 domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013196
- InterPro:   IPR007737
- InterPro:   IPR011608
- InterPro:   IPR016152
- InterPro:   IPR002178
- InterPro:   IPR013011
- InterPro:   IPR003501
- InterPro:   IPR011991 [H]

Pfam domain/function: PF08279 HTH_11; PF05043 Mga; PF00874 PRD; PF02302 PTS_IIB [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 79931; Mature: 79931

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS51094 PTS_EIIA_TYPE_2 ; PS51099 PTS_EIIB_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLDERSNSLLKELLRHPDTSSTNLQAKFGLTRRQVDYSFQKINNWLEEQTYPKIHRAAN
CCCCCHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHCCC
GRFIVEPDLFQIIGEEDGEKTDWYIPSEKERASLIILMLTTGSEELSLNHFISELEVSKN
CCEEECCHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHH
TVLRDLKLVQKTLEKFNLEVKYSRMRGYLIDGDEWNQRTALIYAAEHIIESFGGEEYLQD
HHHHHHHHHHHHHHHHCCEEEEEHHCCEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHH
FMQVDEARIKELREKLEQVEHHLNLHFIDNKMQILPYILEAVFRRMKKGQTITTSFLIDY
HHHHHHHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHHHHCCCEEEEEEEEEH
NELSDTREYGAAEIFIEEEPNMPEAERMYITLQLLTSNVLPKQYLKSEETHKLRLALEQV
HHHHHHHHCCCEEEEEECCCCCCCCHHHEEEHHHHHCCCCCHHHHCCCHHHHHHHHHHHH
LSEFEKKACIQLVDKESLLEKLFAHIKPAYYRIKYHLTTDYSILDKIDQEFQAVHYIVKE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHH
SLAPLERFIGSKVPENESIFITLFIGGHLIESTEKLQTRLKAVVVCPNGLSISRLMEKTL
HHHHHHHHHCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHH
RSLFPEIFFYQAMSIREFEQTKLGYDIVFSAVPLSTDKKFFLINQLMDGKERLELRRRVM
HHHHHHHHHHHHHHHHHHHHHHCCHHHHEEECCCCCCCCCEEHHHHHCCHHHHHHHHHHH
RAVYLVDEVNISVDQLMKTISKFADIKDAARLEKVLADYLMPVPEENTSKHEGKSTLADL
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
LEVTRITRKKSVKDWHEAIYHAALPLLSAGVVEPAYVEEMKRQYPAPIMNIILRNTIAIP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCC
HAETEKGVNSLGMSLLYLEEGLPLEGGKELHFIVVIAAIDKNAHFTALLQLMELSENKKE
CCHHHHCHHHHCCEEEEEECCCCCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHCCCHHH
LKKLADAANTEEMHQIIKNFTDLETKKTM
HHHHHHCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYLDERSNSLLKELLRHPDTSSTNLQAKFGLTRRQVDYSFQKINNWLEEQTYPKIHRAAN
CCCCCHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHCCC
GRFIVEPDLFQIIGEEDGEKTDWYIPSEKERASLIILMLTTGSEELSLNHFISELEVSKN
CCEEECCHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHH
TVLRDLKLVQKTLEKFNLEVKYSRMRGYLIDGDEWNQRTALIYAAEHIIESFGGEEYLQD
HHHHHHHHHHHHHHHHCCEEEEEHHCCEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHH
FMQVDEARIKELREKLEQVEHHLNLHFIDNKMQILPYILEAVFRRMKKGQTITTSFLIDY
HHHHHHHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHHHHCCCEEEEEEEEEH
NELSDTREYGAAEIFIEEEPNMPEAERMYITLQLLTSNVLPKQYLKSEETHKLRLALEQV
HHHHHHHHCCCEEEEEECCCCCCCCHHHEEEHHHHHCCCCCHHHHCCCHHHHHHHHHHHH
LSEFEKKACIQLVDKESLLEKLFAHIKPAYYRIKYHLTTDYSILDKIDQEFQAVHYIVKE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHH
SLAPLERFIGSKVPENESIFITLFIGGHLIESTEKLQTRLKAVVVCPNGLSISRLMEKTL
HHHHHHHHHCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHH
RSLFPEIFFYQAMSIREFEQTKLGYDIVFSAVPLSTDKKFFLINQLMDGKERLELRRRVM
HHHHHHHHHHHHHHHHHHHHHHCCHHHHEEECCCCCCCCCEEHHHHHCCHHHHHHHHHHH
RAVYLVDEVNISVDQLMKTISKFADIKDAARLEKVLADYLMPVPEENTSKHEGKSTLADL
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
LEVTRITRKKSVKDWHEAIYHAALPLLSAGVVEPAYVEEMKRQYPAPIMNIILRNTIAIP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCC
HAETEKGVNSLGMSLLYLEEGLPLEGGKELHFIVVIAAIDKNAHFTALLQLMELSENKKE
CCHHHHCHHHHCCEEEEEECCCCCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHCCCHHH
LKKLADAANTEEMHQIIKNFTDLETKKTM
HHHHHHCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]