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The map label for this gene is rpe [H]

Identifier: 226225212

GI number: 226225212

Start: 2706544

End: 2707218

Strand: Reverse

Name: rpe [H]

Synonym: Lm4b_02634

Alternate gene names: 226225212

Gene position: 2707218-2706544 (Counterclockwise)

Preceding gene: 226225213

Following gene: 226225211

Centisome position: 92.95

GC content: 39.56

Gene sequence:

>675_bases
ATGAGGAAAATAGCCGCTTCAATTATGTGTGCAGACCAACTACATTTAGGTGAAGAGCTCCGTCGCCTTGAATCTGCTGG
TGTGGAACTACTACACTGCGATGTGATGGACGGTGTATATGTGAATAATCTTGCGCTCGGTCCAGAATATTTGGAAATAG
TGCGAAACAATACAGAAATCCCTCTAGACATACATTTGGCTACGATTACCCCACTTAAATATATTGACATGTTTGGTCCT
GTGAAACCGGAATATATTTCTTTTCATGTAGAAGTAGCGGAAGACGTGTCAGAAGTCATCCGGAAAATCCGCTCTTACAA
CGTTAAACCATCGATTGCGATAAATCCAGAAACACCTATCGAAGCCATTTATCCTTATTTAGATGATGTCGAAATGGTGT
TAATGATGACTGTAAACCCGGGTTTTGCGGGACAAAAATTTCAAACAGATGTATTACAAAAGCTACATGATTTAAAAGCA
AAACTAGCTGGAAAAGTCCATGCGCCGCTCATTGAAGTGGATGGCAATATTAATAAAGAAACAGTAGGCTTAATGCGAGA
TTGCTTACCAGACATTTATGTACTAGGCACATCCGCGTTATTTCATGACCGAGATAAAACGAGTTATGCAGAAAGACTAG
TACACATTTGGTCAGATGTAGAAAAACATGTGTAA

Upstream 100 bases:

>100_bases
TTTTAATAGTTGATACTTGGCTTGAGGCATCATTTGCAGGAGATCGCCATAAACGCCGCTTGGATAAAATTACTGAACTC
GAAAGAAAGTGAGGATGAAC

Downstream 100 bases:

>100_bases
TAAAGCACAAACAATTTAAGGGAGATGACAGTTTTGAAAAAAACATTAGATAGACAAGCCGTGGACACGATTCGTTCGTT
ATCCATTGATATGATTGAGA

Product: ribulose-5-phosphate 3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E [H]

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MRKIAASIMCADQLHLGEELRRLESAGVELLHCDVMDGVYVNNLALGPEYLEIVRNNTEIPLDIHLATITPLKYIDMFGP
VKPEYISFHVEVAEDVSEVIRKIRSYNVKPSIAINPETPIEAIYPYLDDVEMVLMMTVNPGFAGQKFQTDVLQKLHDLKA
KLAGKVHAPLIEVDGNINKETVGLMRDCLPDIYVLGTSALFHDRDKTSYAERLVHIWSDVEKHV

Sequences:

>Translated_224_residues
MRKIAASIMCADQLHLGEELRRLESAGVELLHCDVMDGVYVNNLALGPEYLEIVRNNTEIPLDIHLATITPLKYIDMFGP
VKPEYISFHVEVAEDVSEVIRKIRSYNVKPSIAINPETPIEAIYPYLDDVEMVLMMTVNPGFAGQKFQTDVLQKLHDLKA
KLAGKVHAPLIEVDGNINKETVGLMRDCLPDIYVLGTSALFHDRDKTSYAERLVHIWSDVEKHV
>Mature_224_residues
MRKIAASIMCADQLHLGEELRRLESAGVELLHCDVMDGVYVNNLALGPEYLEIVRNNTEIPLDIHLATITPLKYIDMFGP
VKPEYISFHVEVAEDVSEVIRKIRSYNVKPSIAINPETPIEAIYPYLDDVEMVLMMTVNPGFAGQKFQTDVLQKLHDLKA
KLAGKVHAPLIEVDGNINKETVGLMRDCLPDIYVLGTSALFHDRDKTSYAERLVHIWSDVEKHV

Specific function: D-ALLOSE METABOLISM. ESSENTIAL FOR THIS PATHWAY. [C]

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=222, Percent_Identity=31.981981981982, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI219879828, Length=222, Percent_Identity=30.6306306306306, Blast_Score=111, Evalue=5e-25,
Organism=Homo sapiens, GI24307923, Length=177, Percent_Identity=26.5536723163842, Blast_Score=74, Evalue=9e-14,
Organism=Escherichia coli, GI1790523, Length=213, Percent_Identity=34.7417840375587, Blast_Score=131, Evalue=3e-32,
Organism=Escherichia coli, GI1789788, Length=220, Percent_Identity=32.2727272727273, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1790754, Length=156, Percent_Identity=27.5641025641026, Blast_Score=91, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17552948, Length=200, Percent_Identity=31.5, Blast_Score=110, Evalue=8e-25,
Organism=Saccharomyces cerevisiae, GI6322341, Length=210, Percent_Identity=32.8571428571429, Blast_Score=119, Evalue=5e-28,
Organism=Drosophila melanogaster, GI24586301, Length=199, Percent_Identity=32.1608040201005, Blast_Score=108, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: =5.1.3.1 [H]

Molecular weight: Translated: 25266; Mature: 25266

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS01086 RIBUL_P_3_EPIMER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKIAASIMCADQLHLGEELRRLESAGVELLHCDVMDGVYVNNLALGPEYLEIVRNNTEI
CCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEECCEECCHHHHHHHHCCCCC
PLDIHLATITPLKYIDMFGPVKPEYISFHVEVAEDVSEVIRKIRSYNVKPSIAINPETPI
EEEEEEEEECHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCEEECCCCCH
EAIYPYLDDVEMVLMMTVNPGFAGQKFQTDVLQKLHDLKAKLAGKVHAPLIEVDGNINKE
HHHHHHHCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHH
TVGLMRDCLPDIYVLGTSALFHDRDKTSYAERLVHIWSDVEKHV
HHHHHHHHCCHHEECCCHHHHCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRKIAASIMCADQLHLGEELRRLESAGVELLHCDVMDGVYVNNLALGPEYLEIVRNNTEI
CCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEECCEECCHHHHHHHHCCCCC
PLDIHLATITPLKYIDMFGPVKPEYISFHVEVAEDVSEVIRKIRSYNVKPSIAINPETPI
EEEEEEEEECHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCEEECCCCCH
EAIYPYLDDVEMVLMMTVNPGFAGQKFQTDVLQKLHDLKAKLAGKVHAPLIEVDGNINKE
HHHHHHHCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHH
TVGLMRDCLPDIYVLGTSALFHDRDKTSYAERLVHIWSDVEKHV
HHHHHHHHCCHHEECCCHHHHCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]