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The map label for this gene is lytG [H]

Identifier: 226225137

GI number: 226225137

Start: 2646314

End: 2647840

Strand: Direct

Name: lytG [H]

Synonym: Lm4b_02558

Alternate gene names: 226225137

Gene position: 2646314-2647840 (Clockwise)

Preceding gene: 226225133

Following gene: 226225141

Centisome position: 90.85

GC content: 38.24

Gene sequence:

>1527_bases
TTGGATAGAAAGTTTATAAAACCAGGGATAATTCTGCTAATTGTGGCATTTTTGGTAGTTTCCATAAATGTTGGAGCGGA
AACAGGAGGTAGCAGAACAGCTCAAGTTAATCTGACTACTTCACAACAAGCTTTCATTGATGAAATTTTACCAGCGGCTC
AGGATGGATATCGCGATGGTAAATTGCTTACAAGTGTAACGCTCGCTCAAGCAATTTTAGAATCAAATTGGGGTGAAAGT
GGTCTAAGCCAGAACTCTAATAACTTATTCGGAATTAAAGGAACGTATAAAGGTGAGTCTGTCTCCATGGGGACAATGGA
AGCATCCGGCTCAACAACCGCTAATTTCCGCGTTTACCCTAGTTGGAAAGAATCCATTGAAGACCACACAGCTTTAATTA
CTGAAAATGCGCGCTATCAAGACGCTGTCGGTGAAACGAACTACCGCAAAGCACTGCAAGCTATTAAAGACGGTGGTTAT
GCGACTGATCCAGATTACGTTTCTAAACTAGTAGCAATTATTGAACGTTACAACTTAGATAAATACGATGTCATTTACGA
TAAAATCGAGTCTAATCAATCCTTAGCAGCAATTGGAACAGTAGCTGAAAATAAAGAACAAGAGGTTATTTGGTCGGCAC
CGTACAATACAGAAAATGCTAATAAAATCGGGACCCTCGAAAATTACTTAGGGCGTAACTTAGAAATTTCCTGGGAAGCT
AAAACAGAAAAAGGTCTATGGTACTTTATTCGCGAGAACAACAAAGATATTGGTTGGATAAATAGTAATGCCTTAAAAAT
CAGCTATCATCAAAAAGAAGATGAAAATGTTCATTTAACCAAATATGTAGATGATTTAAGCGCACATGTATATCGTCTAC
CAAGCCCTGAAAAACAATTCGATAATGGAACTATCGCAAAATACGATAGAAAAGCCCTTGAAGTAGATAAAAAAATCACT
CGCGGGGGCTATGCTTGGTTCCGAATTTCAGAAGGCGAGAAAGTAATTGGCTGGGTTCGCGCGGATAAGTTGAATGATCG
CCTTTATGATCGCATCACAGAACAAACTTCTTACGATGGCTATGCTCTAGTAAGTAAATCTGCAACTGATAACGTATGGA
CTGCACCATTCAACACAAAAAACGCAGAAAAATTAGCACCACTTGCAGATTATGATAACGAAAAACTAGAACTAGTGACT
CGAGCTAAAGCCGGAAATACACTTTGGTATCAGTTTAAAGTAGATGGAAAACTTGTTGGATGGGCTAGCGAAAAAGACTT
AAATGTATTTTATACTCCCGCTAAAGAAGAACCAGTAAAACAAGTCGCTTACGTGAAAGACCCAACAGCAAAACTTTATA
ACAAACCTGTAGAATCAACAAGTACTAACCCAAAAGCAGTGGGCTTCTATTATGGAAAATTATTAGCAGTGGATAAAACA
GCAACCATTCTTGGTGAAGATTGGTTGCATCTTAAAGACAGACAAAATTCACTAGGATGGATTAAAGCTATCGACATCAA
TAGTTAA

Upstream 100 bases:

>100_bases
TTGGCGTAGTTATTGTTTTTCGTCATAGAAATGTAATAGAAATTTTTTGGCATTTTTTGATAATATAGTTGCAGATATAT
AAAAAGGAGTGCATTGAAAT

Downstream 100 bases:

>100_bases
ATAAAAAAAGGTTCTGCATTTACGCAGAACCTTTTTTCGTTTATACATTCAGTTTGCGACTAGCCATCCATTTCACCATT
TCTGGATCCGCATGTGAGAA

Product: N-acetylmuramoyl-L-alanine amidase

Products: NA

Alternate protein names: Autolysin lytG; Exo-beta-N-acetylglucosaminidase lytG; Peptidoglycan hydrolase lytG [H]

Number of amino acids: Translated: 508; Mature: 508

Protein sequence:

>508_residues
MDRKFIKPGIILLIVAFLVVSINVGAETGGSRTAQVNLTTSQQAFIDEILPAAQDGYRDGKLLTSVTLAQAILESNWGES
GLSQNSNNLFGIKGTYKGESVSMGTMEASGSTTANFRVYPSWKESIEDHTALITENARYQDAVGETNYRKALQAIKDGGY
ATDPDYVSKLVAIIERYNLDKYDVIYDKIESNQSLAAIGTVAENKEQEVIWSAPYNTENANKIGTLENYLGRNLEISWEA
KTEKGLWYFIRENNKDIGWINSNALKISYHQKEDENVHLTKYVDDLSAHVYRLPSPEKQFDNGTIAKYDRKALEVDKKIT
RGGYAWFRISEGEKVIGWVRADKLNDRLYDRITEQTSYDGYALVSKSATDNVWTAPFNTKNAEKLAPLADYDNEKLELVT
RAKAGNTLWYQFKVDGKLVGWASEKDLNVFYTPAKEEPVKQVAYVKDPTAKLYNKPVESTSTNPKAVGFYYGKLLAVDKT
ATILGEDWLHLKDRQNSLGWIKAIDINS

Sequences:

>Translated_508_residues
MDRKFIKPGIILLIVAFLVVSINVGAETGGSRTAQVNLTTSQQAFIDEILPAAQDGYRDGKLLTSVTLAQAILESNWGES
GLSQNSNNLFGIKGTYKGESVSMGTMEASGSTTANFRVYPSWKESIEDHTALITENARYQDAVGETNYRKALQAIKDGGY
ATDPDYVSKLVAIIERYNLDKYDVIYDKIESNQSLAAIGTVAENKEQEVIWSAPYNTENANKIGTLENYLGRNLEISWEA
KTEKGLWYFIRENNKDIGWINSNALKISYHQKEDENVHLTKYVDDLSAHVYRLPSPEKQFDNGTIAKYDRKALEVDKKIT
RGGYAWFRISEGEKVIGWVRADKLNDRLYDRITEQTSYDGYALVSKSATDNVWTAPFNTKNAEKLAPLADYDNEKLELVT
RAKAGNTLWYQFKVDGKLVGWASEKDLNVFYTPAKEEPVKQVAYVKDPTAKLYNKPVESTSTNPKAVGFYYGKLLAVDKT
ATILGEDWLHLKDRQNSLGWIKAIDINS
>Mature_508_residues
MDRKFIKPGIILLIVAFLVVSINVGAETGGSRTAQVNLTTSQQAFIDEILPAAQDGYRDGKLLTSVTLAQAILESNWGES
GLSQNSNNLFGIKGTYKGESVSMGTMEASGSTTANFRVYPSWKESIEDHTALITENARYQDAVGETNYRKALQAIKDGGY
ATDPDYVSKLVAIIERYNLDKYDVIYDKIESNQSLAAIGTVAENKEQEVIWSAPYNTENANKIGTLENYLGRNLEISWEA
KTEKGLWYFIRENNKDIGWINSNALKISYHQKEDENVHLTKYVDDLSAHVYRLPSPEKQFDNGTIAKYDRKALEVDKKIT
RGGYAWFRISEGEKVIGWVRADKLNDRLYDRITEQTSYDGYALVSKSATDNVWTAPFNTKNAEKLAPLADYDNEKLELVT
RAKAGNTLWYQFKVDGKLVGWASEKDLNVFYTPAKEEPVKQVAYVKDPTAKLYNKPVESTSTNPKAVGFYYGKLLAVDKT
ATILGEDWLHLKDRQNSLGWIKAIDINS

Specific function: Is the major glucosaminidase responsible for peptidoglycan structural determination during vegetative growth. Acts processively from the ends of the glycan strands. Also plays a role in motility, chemotaxis and cell division [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted, cell wall [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 73 family [H]

Homologues:

Organism=Escherichia coli, GI1787321, Length=169, Percent_Identity=32.5443786982249, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000423
- InterPro:   IPR013338
- InterPro:   IPR002901 [H]

Pfam domain/function: PF01832 Glucosaminidase [H]

EC number: 3.2.1.- [C]

Molecular weight: Translated: 57061; Mature: 57061

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRKFIKPGIILLIVAFLVVSINVGAETGGSRTAQVNLTTSQQAFIDEILPAAQDGYRDG
CCCCCCCCCHHHHHHHHHHHEEECCCCCCCCEEEEEEEECCHHHHHHHHHHHHCCCCCCC
KLLTSVTLAQAILESNWGESGLSQNSNNLFGIKGTYKGESVSMGTMEASGSTTANFRVYP
HHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEEECCCCCEEEEEECC
SWKESIEDHTALITENARYQDAVGETNYRKALQAIKDGGYATDPDYVSKLVAIIERYNLD
CHHHHHCCCEEEEECCCCHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCC
KYDVIYDKIESNQSLAAIGTVAENKEQEVIWSAPYNTENANKIGTLENYLGRNLEISWEA
HHHHHHHHHCCCCCEEEEEEHHCCCCCEEEEECCCCCCCCCCCCCHHHHCCCCEEEEEEC
KTEKGLWYFIRENNKDIGWINSNALKISYHQKEDENVHLTKYVDDLSAHVYRLPSPEKQF
CCCCCEEEEEEECCCEEEEECCCEEEEEEECCCCCCEEEHHHHHHHHHHEEECCCCHHHC
DNGTIAKYDRKALEVDKKITRGGYAWFRISEGEKVIGWVRADKLNDRLYDRITEQTSYDG
CCCCEEHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEEECCHHHHHHHHHHHHHCCCCC
YALVSKSATDNVWTAPFNTKNAEKLAPLADYDNEKLELVTRAKAGNTLWYQFKVDGKLVG
EEEEECCCCCCEEECCCCCCCHHHCCCCCCCCCCEEEEEEEECCCCEEEEEEEECCEEEE
WASEKDLNVFYTPAKEEPVKQVAYVKDPTAKLYNKPVESTSTNPKAVGFYYGKLLAVDKT
ECCCCCCEEEECCCCCCCHHHHHEECCCHHHHHCCCCCCCCCCCCEEEEEEEEEEEECCH
ATILGEDWLHLKDRQNSLGWIKAIDINS
HEEECCCCEEECCCCCCCCEEEEEECCC
>Mature Secondary Structure
MDRKFIKPGIILLIVAFLVVSINVGAETGGSRTAQVNLTTSQQAFIDEILPAAQDGYRDG
CCCCCCCCCHHHHHHHHHHHEEECCCCCCCCEEEEEEEECCHHHHHHHHHHHHCCCCCCC
KLLTSVTLAQAILESNWGESGLSQNSNNLFGIKGTYKGESVSMGTMEASGSTTANFRVYP
HHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEEECCCCCEEEEEECC
SWKESIEDHTALITENARYQDAVGETNYRKALQAIKDGGYATDPDYVSKLVAIIERYNLD
CHHHHHCCCEEEEECCCCHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCC
KYDVIYDKIESNQSLAAIGTVAENKEQEVIWSAPYNTENANKIGTLENYLGRNLEISWEA
HHHHHHHHHCCCCCEEEEEEHHCCCCCEEEEECCCCCCCCCCCCCHHHHCCCCEEEEEEC
KTEKGLWYFIRENNKDIGWINSNALKISYHQKEDENVHLTKYVDDLSAHVYRLPSPEKQF
CCCCCEEEEEEECCCEEEEECCCEEEEEEECCCCCCEEEHHHHHHHHHHEEECCCCHHHC
DNGTIAKYDRKALEVDKKITRGGYAWFRISEGEKVIGWVRADKLNDRLYDRITEQTSYDG
CCCCEEHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEEECCHHHHHHHHHHHHHCCCCC
YALVSKSATDNVWTAPFNTKNAEKLAPLADYDNEKLELVTRAKAGNTLWYQFKVDGKLVG
EEEEECCCCCCEEECCCCCCCHHHCCCCCCCCCCEEEEEEEECCCCEEEEEEEECCEEEE
WASEKDLNVFYTPAKEEPVKQVAYVKDPTAKLYNKPVESTSTNPKAVGFYYGKLLAVDKT
ECCCCCCEEEECCCCCCCHHHHHEECCCHHHHHCCCCCCCCCCCCEEEEEEEEEEEECCH
ATILGEDWLHLKDRQNSLGWIKAIDINS
HEEECCCCEEECCCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]