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The map label for this gene is mrpE [H]

Identifier: 226224934

GI number: 226224934

Start: 2431554

End: 2432033

Strand: Direct

Name: mrpE [H]

Synonym: Lm4b_02354

Alternate gene names: 226224934

Gene position: 2431554-2432033 (Clockwise)

Preceding gene: 226224933

Following gene: 226224935

Centisome position: 83.48

GC content: 38.54

Gene sequence:

>480_bases
ATGGCTTTTCAACTTATTCTTAATATAATACTTGCTTGTTTGTGGATGTTTCTTGAGTCATCATTTAGTTTTGCAACATT
TATCATTGGCTTTATCATCGGGATTTTCTTGCTATTCTTTATGCGACGTTTCCTTGGATCAAGATTTTACCTTTTCCGGT
TATTCGCCCTTGTCAAACTGGTTTTCCGCTTTTTGCATGATTTAATTGTTTCTACAGTTCATGTAAGTCGGATTGTTTTA
AAGAAAGACATGAACATTCGACCGGGGATTTTCAGATATGATACGACGCTTGAGACAGACTGGGAAGTGACGATGCTCGC
ACTACTGATTACGTTAACGCCCGGGACACTTTCGATTGATATTTCGGATGATTATAAAGCAATCTATGTCCACTCGCTTC
ACGTCCCTAATATTGAAGAAGAAATTGCAACAATTCGTAAGTCTTATGAAGGCGCGATTATGGAGGTGTTCCACGGATGA

Upstream 100 bases:

>100_bases
TGTGTTTAGTAATGCAATTTATCCGTTTATTGAACAGGCGGTTGACCCTCTTGTTGACCCTTCTGTTTATATCCATGCGG
TGATAAAGGAGTGATAAAAG

Downstream 100 bases:

>100_bases
TTATTCAAATCGCTTTATCCATTGGTTTACTTCTCTATTCGATTTCAACTTTCTTATATCTTTACCGTATTTTAAAAGGA
CCAACTACTTCTGACAAAGT

Product: putative monovalent cation/H+ antiporter subunit E

Products: NA

Alternate protein names: Mrp complex subunit E; Multiple resistance and pH homeostasis protein E [H]

Number of amino acids: Translated: 159; Mature: 158

Protein sequence:

>159_residues
MAFQLILNIILACLWMFLESSFSFATFIIGFIIGIFLLFFMRRFLGSRFYLFRLFALVKLVFRFLHDLIVSTVHVSRIVL
KKDMNIRPGIFRYDTTLETDWEVTMLALLITLTPGTLSIDISDDYKAIYVHSLHVPNIEEEIATIRKSYEGAIMEVFHG

Sequences:

>Translated_159_residues
MAFQLILNIILACLWMFLESSFSFATFIIGFIIGIFLLFFMRRFLGSRFYLFRLFALVKLVFRFLHDLIVSTVHVSRIVL
KKDMNIRPGIFRYDTTLETDWEVTMLALLITLTPGTLSIDISDDYKAIYVHSLHVPNIEEEIATIRKSYEGAIMEVFHG
>Mature_158_residues
AFQLILNIILACLWMFLESSFSFATFIIGFIIGIFLLFFMRRFLGSRFYLFRLFALVKLVFRFLHDLIVSTVHVSRIVLK
KDMNIRPGIFRYDTTLETDWEVTMLALLITLTPGTLSIDISDDYKAIYVHSLHVPNIEEEIATIRKSYEGAIMEVFHG

Specific function: Mrp complex is a Na(+)/H(+) antiporter involved in Na(+) excretion and Na(+) resistance [H]

COG id: COG1863

COG function: function code P; Multisubunit Na+/H+ antiporter, MnhE subunit

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002758 [H]

Pfam domain/function: PF01899 MNHE [H]

EC number: NA

Molecular weight: Translated: 18525; Mature: 18394

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFQLILNIILACLWMFLESSFSFATFIIGFIIGIFLLFFMRRFLGSRFYLFRLFALVKL
CHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
VFRFLHDLIVSTVHVSRIVLKKDMNIRPGIFRYDTTLETDWEVTMLALLITLTPGTLSID
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHCCCCEEEEE
ISDDYKAIYVHSLHVPNIEEEIATIRKSYEGAIMEVFHG
ECCCCEEEEEEECCCCCHHHHHHHHHHHHCCHHHHHHCC
>Mature Secondary Structure 
AFQLILNIILACLWMFLESSFSFATFIIGFIIGIFLLFFMRRFLGSRFYLFRLFALVKL
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
VFRFLHDLIVSTVHVSRIVLKKDMNIRPGIFRYDTTLETDWEVTMLALLITLTPGTLSID
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHCCCCEEEEE
ISDDYKAIYVHSLHVPNIEEEIATIRKSYEGAIMEVFHG
ECCCCEEEEEEECCCCCHHHHHHHHHHHHCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11356194 [H]