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The map label for this gene is murG

Identifier: 226224641

GI number: 226224641

Start: 2115849

End: 2116940

Strand: Reverse

Name: murG

Synonym: Lm4b_02056

Alternate gene names: 226224641

Gene position: 2116940-2115849 (Counterclockwise)

Preceding gene: 226224642

Following gene: 226224640

Centisome position: 72.68

GC content: 39.47

Gene sequence:

>1092_bases
ATGAAAGTAGCAATAAGTGGTGGCGGTACTGGTGGACACGTTTATCCAGCGCTTGCTCTCATCAGAGAATTAAAAAAAAT
TCATCCTGAAGCGGAATTTTTATATATCGGAACAGAAAAAGGCCTAGAAGCTGGAATCGTTAAACGTGAAGGGATTCCGT
TTGAAGCTATTGAAATTACTGGTTTCAAACGTTCATTATCGTTAGAAAATATTAAAACAGTAATGCGTTTTCTGAGCGGC
GCGAAAAAAAGTAAACAAATTTTGCGCGATTTTAAACCGGATGTCGTTATCGGAACAGGTGGTTATGTTTGTGGTCCAGT
CGTTTATGCAGCCGCAAAACTTAAAATTCCTACTTTAATCCACGAACAAAATAGTGTTGCTGGATTAACGAATAAATTTT
TAAGCCGCTACACAGATAAAGTAGCCATTTGTTTTGAAGAAGTAAGTGATTCTTTCGCATCGGAAAAAATCGTTTTCACT
GGTAATCCACGTGCTTCTGAAGTTGTAGGTGTGGACTCGGAAGGTGCACTGGAAACTTACGGACTAGTTTCAGGGAAGCC
AACTGTGCTTGTTTTTGGAGGCAGTAGAGGAGCTCGCGGCGTGAATGAAGCGGTAGAAGCTATTTTGCCAGAATGGAATA
ATCGGGATTTTCAGCTACTTTATGTAACGGGCGATGTACACTATGAAAAAATAAAAGATTCTTTGGCGGAGTTGAATTTG
GGTAATCATATTAGTGTTCAACCATTTATTTATGATATGCCAAAAATTTTAAACGCTGTGACGCTCGTTGTTTCAAGAGC
AGGAGCGACTACACTTGCAGAACTTACAGCGCTAGGGGTTCCAAGTATTTTGATACCTAGTCCATACGTGACAGCAAACC
ACCAAGAAAATAACGCTCGCGCTTTAGAAAAAAATAATGCAGCTATCGTAATTACAGAAGCAGAATTAAAAAATACCGAT
TTAATGGCGACAGTTGATTCGATTTTGAATGACGAGGCGAAATTAAATGGTATGAAGCTAAGTGCTAAACAAATGGGGCG
CCCAGATGCAGCAGCGAAATTAGTAGAAGCAGTCCTTAGCATTATGAAATAA

Upstream 100 bases:

>100_bases
TTTCACCAGCATGTGCGAGTTGGGATCAATACCGAACATTTGAAGTTCGCGGGAATGCCTATATGGACGCAATCGGCGAG
CTAATAGAAGAGGTGGAAAA

Downstream 100 bases:

>100_bases
ATCGCAGAAAGGAGCGAATAAAATGGCTGAAAATAAACGAGTAATTTCAATTGAAAATCGCATACCAGAACTCAAAAAAT
ACCGCAAAAAAAAATTAGTA

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase [H]

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MKVAISGGGTGGHVYPALALIRELKKIHPEAEFLYIGTEKGLEAGIVKREGIPFEAIEITGFKRSLSLENIKTVMRFLSG
AKKSKQILRDFKPDVVIGTGGYVCGPVVYAAAKLKIPTLIHEQNSVAGLTNKFLSRYTDKVAICFEEVSDSFASEKIVFT
GNPRASEVVGVDSEGALETYGLVSGKPTVLVFGGSRGARGVNEAVEAILPEWNNRDFQLLYVTGDVHYEKIKDSLAELNL
GNHISVQPFIYDMPKILNAVTLVVSRAGATTLAELTALGVPSILIPSPYVTANHQENNARALEKNNAAIVITEAELKNTD
LMATVDSILNDEAKLNGMKLSAKQMGRPDAAAKLVEAVLSIMK

Sequences:

>Translated_363_residues
MKVAISGGGTGGHVYPALALIRELKKIHPEAEFLYIGTEKGLEAGIVKREGIPFEAIEITGFKRSLSLENIKTVMRFLSG
AKKSKQILRDFKPDVVIGTGGYVCGPVVYAAAKLKIPTLIHEQNSVAGLTNKFLSRYTDKVAICFEEVSDSFASEKIVFT
GNPRASEVVGVDSEGALETYGLVSGKPTVLVFGGSRGARGVNEAVEAILPEWNNRDFQLLYVTGDVHYEKIKDSLAELNL
GNHISVQPFIYDMPKILNAVTLVVSRAGATTLAELTALGVPSILIPSPYVTANHQENNARALEKNNAAIVITEAELKNTD
LMATVDSILNDEAKLNGMKLSAKQMGRPDAAAKLVEAVLSIMK
>Mature_363_residues
MKVAISGGGTGGHVYPALALIRELKKIHPEAEFLYIGTEKGLEAGIVKREGIPFEAIEITGFKRSLSLENIKTVMRFLSG
AKKSKQILRDFKPDVVIGTGGYVCGPVVYAAAKLKIPTLIHEQNSVAGLTNKFLSRYTDKVAICFEEVSDSFASEKIVFT
GNPRASEVVGVDSEGALETYGLVSGKPTVLVFGGSRGARGVNEAVEAILPEWNNRDFQLLYVTGDVHYEKIKDSLAELNL
GNHISVQPFIYDMPKILNAVTLVVSRAGATTLAELTALGVPSILIPSPYVTANHQENNARALEKNNAAIVITEAELKNTD
LMATVDSILNDEAKLNGMKLSAKQMGRPDAAAKLVEAVLSIMK

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) [H]

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786278, Length=364, Percent_Identity=31.3186813186813, Blast_Score=161, Evalue=5e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235 [H]

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28 [H]

EC number: =2.4.1.227 [H]

Molecular weight: Translated: 39056; Mature: 39056

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVAISGGGTGGHVYPALALIRELKKIHPEAEFLYIGTEKGLEAGIVKREGIPFEAIEIT
CEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEECCCCCEEEEEEE
GFKRSLSLENIKTVMRFLSGAKKSKQILRDFKPDVVIGTGGYVCGPVVYAAAKLKIPTLI
CCHHHCCHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHEECCCEE
HEQNSVAGLTNKFLSRYTDKVAICFEEVSDSFASEKIVFTGNPRASEVVGVDSEGALETY
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCEEEECCCCCCCEEE
GLVSGKPTVLVFGGSRGARGVNEAVEAILPEWNNRDFQLLYVTGDVHYEKIKDSLAELNL
EEECCCCEEEEECCCCCCCHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHCCC
GNHISVQPFIYDMPKILNAVTLVVSRAGATTLAELTALGVPSILIPSPYVTANHQENNAR
CCCEEECHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEECCCCEEECCCCCCCCH
ALEKNNAAIVITEAELKNTDLMATVDSILNDEAKLNGMKLSAKQMGRPDAAAKLVEAVLS
HEECCCCEEEEEECCCCCCHHHHHHHHHHCCHHHCCCEEEEHHHCCCCHHHHHHHHHHHH
IMK
HHC
>Mature Secondary Structure
MKVAISGGGTGGHVYPALALIRELKKIHPEAEFLYIGTEKGLEAGIVKREGIPFEAIEIT
CEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEECCCCCEEEEEEE
GFKRSLSLENIKTVMRFLSGAKKSKQILRDFKPDVVIGTGGYVCGPVVYAAAKLKIPTLI
CCHHHCCHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHEECCCEE
HEQNSVAGLTNKFLSRYTDKVAICFEEVSDSFASEKIVFTGNPRASEVVGVDSEGALETY
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCEEEECCCCCCCEEE
GLVSGKPTVLVFGGSRGARGVNEAVEAILPEWNNRDFQLLYVTGDVHYEKIKDSLAELNL
EEECCCCEEEEECCCCCCCHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHCCC
GNHISVQPFIYDMPKILNAVTLVVSRAGATTLAELTALGVPSILIPSPYVTANHQENNAR
CCCEEECHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEECCCCEEECCCCCCCCH
ALEKNNAAIVITEAELKNTDLMATVDSILNDEAKLNGMKLSAKQMGRPDAAAKLVEAVLS
HEECCCCEEEEEECCCCCCHHHHHHHHHHCCHHHCCCEEEEHHHCCCCHHHHHHHHHHHH
IMK
HHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]