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The map label for this gene is tyrA

Identifier: 226224528

GI number: 226224528

Start: 1987333

End: 1988436

Strand: Reverse

Name: tyrA

Synonym: Lm4b_01941

Alternate gene names: 226224528

Gene position: 1988436-1987333 (Counterclockwise)

Preceding gene: 226224529

Following gene: 226224527

Centisome position: 68.27

GC content: 41.85

Gene sequence:

>1104_bases
ATGAAAGGGACGGTAGTTATTGTTGGGCTTGGGTTAATTGGCGGTTCTATTGCCCTTGCGATTAAAGCCAAACACCCAGA
AGCACATATCATCGGAATTGACGTTTCCTATCATTCGTTAGAAGTTGGAAAGTCTCTCGGTGTGATTGACGAAATTGGCG
AAAGTATTTTAATAGATGGGCCAAAAGCAGATTTACTTGTTTTTTGTTGTCCGGTAAAAGAAACAGAACAGTTATTAACG
CGTTTACCAGGGCTGCGTTTAAAGGAAAATGTGATCGTTACAGATACAGGTAGTACAAAAGGAACCATCATGGAAGCATC
CACGGCACTTAGAGAAAGTGGTATTACGTTTATTGGCGGTCATCCAATGGCTGGTTCGCATAAAAGTGGTGTCCGTGCTG
CTAAAGAACTGTTGTTTGAAAATGCCTATTATTTGTTAACACCAACGAAAGATGTAGCAGAAGACAAAGTGGCTGAACTT
AGGACGTGGCTGTCTGGTACGAATGCTAAGTTCTTAGTGTTATCACCAAATGAGCATGATGAAATTACTGGCATGTTGAG
CCACTTACCGCATATTGTGGCGGCGGCTTTAGTGAACCAGACGCAAAGCTTTACAGAAGAACATCCTGCAGCATTTCGAC
TTGCGGCAGGCGGATTTCGTGATATTACACGGGTCGCTTCTTCTGATCCAAGAATGTGGACGGATATTTCTATTAGCAAC
CAAAAAACGTTAACGAAACAGCTGACGATTTGGCGAGACAGTATGAACGAAGCGCTTGAGATGCTTGAAAGTGAAGACGC
GAGTTCTATATATGCCTTTTTTGATGGGGCAAAAGAATTTCGAGATTCACTTCCAGTTCATCAAGGTGGTGCGATTCCAT
CTTTTTACGATTTATTTGTCGATGTACCAGATTATCCAGGGGTAATTTCTGAAGTGACTAGGTATCTGGGCGAAGAAGAA
ATCAGTTTAACAAACATCAAGATTTTGGAAACACGGGAAGATATTTTCGGTGTGTTACAAATTACTTTCCAATCGGATGA
AGACAGGGACCGGGCGAAACGTTGCATTGAAACAAGAAGTAACTATACATGCCATTACGAATAG

Upstream 100 bases:

>100_bases
TTCCAACTGCTGTTCGAATTACGATCGGAAAAGAAGAGGAAAATAGTGCGGTAATTGCACTTTTAGAAAAATTATTGTAA
GTGTTTGGAGGCGTTTTTGA

Downstream 100 bases:

>100_bases
GAGAGAAATGACGATGAAATTAATTACAAATAAACAAGGGCTGGTTGGCGCAATCACAGTCCCTGGAGATAAATCAATGT
CCCATCGCAGCATTATGTTC

Product: prephenate dehydrogenase

Products: NA

Alternate protein names: PDH [H]

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MKGTVVIVGLGLIGGSIALAIKAKHPEAHIIGIDVSYHSLEVGKSLGVIDEIGESILIDGPKADLLVFCCPVKETEQLLT
RLPGLRLKENVIVTDTGSTKGTIMEASTALRESGITFIGGHPMAGSHKSGVRAAKELLFENAYYLLTPTKDVAEDKVAEL
RTWLSGTNAKFLVLSPNEHDEITGMLSHLPHIVAAALVNQTQSFTEEHPAAFRLAAGGFRDITRVASSDPRMWTDISISN
QKTLTKQLTIWRDSMNEALEMLESEDASSIYAFFDGAKEFRDSLPVHQGGAIPSFYDLFVDVPDYPGVISEVTRYLGEEE
ISLTNIKILETREDIFGVLQITFQSDEDRDRAKRCIETRSNYTCHYE

Sequences:

>Translated_367_residues
MKGTVVIVGLGLIGGSIALAIKAKHPEAHIIGIDVSYHSLEVGKSLGVIDEIGESILIDGPKADLLVFCCPVKETEQLLT
RLPGLRLKENVIVTDTGSTKGTIMEASTALRESGITFIGGHPMAGSHKSGVRAAKELLFENAYYLLTPTKDVAEDKVAEL
RTWLSGTNAKFLVLSPNEHDEITGMLSHLPHIVAAALVNQTQSFTEEHPAAFRLAAGGFRDITRVASSDPRMWTDISISN
QKTLTKQLTIWRDSMNEALEMLESEDASSIYAFFDGAKEFRDSLPVHQGGAIPSFYDLFVDVPDYPGVISEVTRYLGEEE
ISLTNIKILETREDIFGVLQITFQSDEDRDRAKRCIETRSNYTCHYE
>Mature_367_residues
MKGTVVIVGLGLIGGSIALAIKAKHPEAHIIGIDVSYHSLEVGKSLGVIDEIGESILIDGPKADLLVFCCPVKETEQLLT
RLPGLRLKENVIVTDTGSTKGTIMEASTALRESGITFIGGHPMAGSHKSGVRAAKELLFENAYYLLTPTKDVAEDKVAEL
RTWLSGTNAKFLVLSPNEHDEITGMLSHLPHIVAAALVNQTQSFTEEHPAAFRLAAGGFRDITRVASSDPRMWTDISISN
QKTLTKQLTIWRDSMNEALEMLESEDASSIYAFFDGAKEFRDSLPVHQGGAIPSFYDLFVDVPDYPGVISEVTRYLGEEE
ISLTNIKILETREDIFGVLQITFQSDEDRDRAKRCIETRSNYTCHYE

Specific function: Unknown

COG id: COG0287

COG function: function code E; Prephenate dehydrogenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate/arogenate dehydrogenase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR002912
- InterPro:   IPR016040
- InterPro:   IPR003099 [H]

Pfam domain/function: PF01842 ACT; PF02153 PDH [H]

EC number: =1.3.1.12 [H]

Molecular weight: Translated: 40358; Mature: 40358

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGTVVIVGLGLIGGSIALAIKAKHPEAHIIGIDVSYHSLEVGKSLGVIDEIGESILIDG
CCCEEEEEEECCCCCEEEEEEEECCCCEEEEEEEEEEHHHHHCCCCCCHHHCCCEEEECC
PKADLLVFCCPVKETEQLLTRLPGLRLKENVIVTDTGSTKGTIMEASTALRESGITFIGG
CCCCEEEEECCCHHHHHHHHHCCCCEEECCEEEEECCCCCCEEEHHHHHHHHCCCEEECC
HPMAGSHKSGVRAAKELLFENAYYLLTPTKDVAEDKVAELRTWLSGTNAKFLVLSPNEHD
CCCCCCCHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCH
EITGMLSHLPHIVAAALVNQTQSFTEEHPAAFRLAAGGFRDITRVASSDPRMWTDISISN
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHCCCCCEEEEEECCC
QKTLTKQLTIWRDSMNEALEMLESEDASSIYAFFDGAKEFRDSLPVHQGGAIPSFYDLFV
CHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHCCCCCCCCCCCCHHHHEE
DVPDYPGVISEVTRYLGEEEISLTNIKILETREDIFGVLQITFQSDEDRDRAKRCIETRS
ECCCCCCHHHHHHHHCCCCCEEEEEEEEEECHHHHEEEEEEEECCCCCHHHHHHHHHCCC
NYTCHYE
CEEEECC
>Mature Secondary Structure
MKGTVVIVGLGLIGGSIALAIKAKHPEAHIIGIDVSYHSLEVGKSLGVIDEIGESILIDG
CCCEEEEEEECCCCCEEEEEEEECCCCEEEEEEEEEEHHHHHCCCCCCHHHCCCEEEECC
PKADLLVFCCPVKETEQLLTRLPGLRLKENVIVTDTGSTKGTIMEASTALRESGITFIGG
CCCCEEEEECCCHHHHHHHHHCCCCEEECCEEEEECCCCCCEEEHHHHHHHHCCCEEECC
HPMAGSHKSGVRAAKELLFENAYYLLTPTKDVAEDKVAELRTWLSGTNAKFLVLSPNEHD
CCCCCCCHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCH
EITGMLSHLPHIVAAALVNQTQSFTEEHPAAFRLAAGGFRDITRVASSDPRMWTDISISN
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHCCCCCEEEEEECCC
QKTLTKQLTIWRDSMNEALEMLESEDASSIYAFFDGAKEFRDSLPVHQGGAIPSFYDLFV
CHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHCCCCCCCCCCCCHHHHEE
DVPDYPGVISEVTRYLGEEEISLTNIKILETREDIFGVLQITFQSDEDRDRAKRCIETRS
ECCCCCCHHHHHHHHCCCCCEEEEEEEEEECHHHHEEEEEEEECCCCCHHHHHHHHHCCC
NYTCHYE
CEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3106153; 9384377 [H]