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The map label for this gene is aspB

Identifier: 226224501

GI number: 226224501

Start: 1958208

End: 1959389

Strand: Reverse

Name: aspB

Synonym: Lm4b_01914

Alternate gene names: 226224501

Gene position: 1959389-1958208 (Counterclockwise)

Preceding gene: 226224502

Following gene: 226224500

Centisome position: 67.27

GC content: 37.56

Gene sequence:

>1182_bases
ATGGACTTACCGTTATCAAAACGTGTCAAAGGAGTGGCCCCGTCGCCAACACTTGCGATTACGGCTAAAGCAAAACAAAT
GAAACAAGAAGGAATTGATGTTATCGGCTTAGGTGCTGGGGAACCAGATTTCAATACCCCGCAGAATATTATCGATGCAG
CAATTGAGTCCATGAACAAAGGATTCACCAAATATACTCCTTCTAGTGGAATCATCGAGCTAAAACAAGCGATTGTTGAT
AAGCTCCAAAAAGATCAGTTCTTAAACTACGAAACGAACCAGATTTTCGTAGGTACTGGTGCTAAACATGTACTCTACTC
TGCGTTTCAAACGATTTTAGATCCAGGCGATGAAGTCATTATTCCAGTTCCATATTGGGTAACTTATCCCGAACAAGTCA
AATTAGCAGGTGGTATTCCTGTTTTTGTAGAAACTGGTTTTGACGCGGATTTCAAAATTTCAGCAGCAAATTTTGAAAAA
GCTATCACGAAAAAAACAAAAGCAATCGTTTTAAATTCACCCAATAACCCTTCTGGTATGTGCTATACGAAAGAGGAGCT
TATTGCTATTGGTGAAGTTGCTGAAAAACATCAGATTTACATTTTATCTGATGAAATATACGAAAAATTATACTATGGTA
ACAAAGCTGATTTAGTCTCTATCGCGAGTTTGAGTGACCGTTTGTATGATTTAACTATTGTTATTAATGGTGTATCTAAA
GCATATTCAATGACGGGCTGGCGAATTGGTTACGCAGCTGCAAATAAAGAAATCATTGCTGGAATGAGTAAGTTAGCGGA
TCATTTAACAAGTAATCCAACTGCTAATGCCCAGTATGCTGCACTTGAAGCGTATGTTGGTAGTCAAGAAGTTCCAGAAA
AAATGTACAAAGCTTTTGAAGAACGAATGGAACGTTTTTATCCAGAACTAAGTAGCATTCCAGGTTTTAAACCGAAAAAA
CCAGATGGCGCTTTTTATTTCTTTATTGAAGTAAAAGAAGCGGCACATAAAAAAGGTTTTCAGGATGTAGATGCTTTTGT
AGCAGCTCTTTTAGAAGAAGCGAAAGTCGCAGTCATTCCAGGCTCAGGATTCGGAATGCCTGATTATATACGCCTTTCTT
ATGCAACAAATCCAGACTTATTCCAAGAAGCTATAAATCGAATCAAAAGTTTTATGAAATAG

Upstream 100 bases:

>100_bases
GATAAGAATGACAAGCTAAACTACTTTGACATTAACTTTGAAACAGGTGAATGGTACAGAGAGATTGAAAACTTGTAACT
AAATTGGAGGAGGGAATAAA

Downstream 100 bases:

>100_bases
GGAGTGTAGACAAGTGAAAATTACAATCAATCAAGCATCCGAATTTGTCGGAAAAGAAGTAACTATTGGAGCATGGCTTG
CGAATAAGCGTTCAAGTGGT

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MDLPLSKRVKGVAPSPTLAITAKAKQMKQEGIDVIGLGAGEPDFNTPQNIIDAAIESMNKGFTKYTPSSGIIELKQAIVD
KLQKDQFLNYETNQIFVGTGAKHVLYSAFQTILDPGDEVIIPVPYWVTYPEQVKLAGGIPVFVETGFDADFKISAANFEK
AITKKTKAIVLNSPNNPSGMCYTKEELIAIGEVAEKHQIYILSDEIYEKLYYGNKADLVSIASLSDRLYDLTIVINGVSK
AYSMTGWRIGYAAANKEIIAGMSKLADHLTSNPTANAQYAALEAYVGSQEVPEKMYKAFEERMERFYPELSSIPGFKPKK
PDGAFYFFIEVKEAAHKKGFQDVDAFVAALLEEAKVAVIPGSGFGMPDYIRLSYATNPDLFQEAINRIKSFMK

Sequences:

>Translated_393_residues
MDLPLSKRVKGVAPSPTLAITAKAKQMKQEGIDVIGLGAGEPDFNTPQNIIDAAIESMNKGFTKYTPSSGIIELKQAIVD
KLQKDQFLNYETNQIFVGTGAKHVLYSAFQTILDPGDEVIIPVPYWVTYPEQVKLAGGIPVFVETGFDADFKISAANFEK
AITKKTKAIVLNSPNNPSGMCYTKEELIAIGEVAEKHQIYILSDEIYEKLYYGNKADLVSIASLSDRLYDLTIVINGVSK
AYSMTGWRIGYAAANKEIIAGMSKLADHLTSNPTANAQYAALEAYVGSQEVPEKMYKAFEERMERFYPELSSIPGFKPKK
PDGAFYFFIEVKEAAHKKGFQDVDAFVAALLEEAKVAVIPGSGFGMPDYIRLSYATNPDLFQEAINRIKSFMK
>Mature_393_residues
MDLPLSKRVKGVAPSPTLAITAKAKQMKQEGIDVIGLGAGEPDFNTPQNIIDAAIESMNKGFTKYTPSSGIIELKQAIVD
KLQKDQFLNYETNQIFVGTGAKHVLYSAFQTILDPGDEVIIPVPYWVTYPEQVKLAGGIPVFVETGFDADFKISAANFEK
AITKKTKAIVLNSPNNPSGMCYTKEELIAIGEVAEKHQIYILSDEIYEKLYYGNKADLVSIASLSDRLYDLTIVINGVSK
AYSMTGWRIGYAAANKEIIAGMSKLADHLTSNPTANAQYAALEAYVGSQEVPEKMYKAFEERMERFYPELSSIPGFKPKK
PDGAFYFFIEVKEAAHKKGFQDVDAFVAALLEEAKVAVIPGSGFGMPDYIRLSYATNPDLFQEAINRIKSFMK

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=386, Percent_Identity=28.2383419689119, Blast_Score=146, Evalue=4e-35,
Organism=Homo sapiens, GI56713256, Length=386, Percent_Identity=28.2383419689119, Blast_Score=145, Evalue=5e-35,
Organism=Homo sapiens, GI95147551, Length=424, Percent_Identity=25.2358490566038, Blast_Score=145, Evalue=5e-35,
Organism=Homo sapiens, GI169881279, Length=424, Percent_Identity=25.2358490566038, Blast_Score=145, Evalue=5e-35,
Organism=Homo sapiens, GI4507369, Length=402, Percent_Identity=24.3781094527363, Blast_Score=119, Evalue=7e-27,
Organism=Homo sapiens, GI169881281, Length=419, Percent_Identity=22.9116945107399, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI187936925, Length=207, Percent_Identity=28.9855072463768, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI14211921, Length=207, Percent_Identity=28.9855072463768, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI4885351, Length=342, Percent_Identity=22.2222222222222, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1788627, Length=386, Percent_Identity=29.7927461139896, Blast_Score=164, Evalue=7e-42,
Organism=Escherichia coli, GI1786816, Length=364, Percent_Identity=25, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1788722, Length=393, Percent_Identity=27.4809160305344, Blast_Score=121, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI71994472, Length=364, Percent_Identity=31.043956043956, Blast_Score=151, Evalue=5e-37,
Organism=Caenorhabditis elegans, GI71994476, Length=364, Percent_Identity=31.043956043956, Blast_Score=150, Evalue=8e-37,
Organism=Caenorhabditis elegans, GI17567663, Length=377, Percent_Identity=26.2599469496021, Blast_Score=125, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI17567369, Length=330, Percent_Identity=28.1818181818182, Blast_Score=122, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6322401, Length=390, Percent_Identity=24.8717948717949, Blast_Score=135, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6320317, Length=339, Percent_Identity=22.7138643067847, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI28573069, Length=357, Percent_Identity=30.2521008403361, Blast_Score=139, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24646114, Length=357, Percent_Identity=30.2521008403361, Blast_Score=139, Evalue=3e-33,
Organism=Drosophila melanogaster, GI28573067, Length=357, Percent_Identity=30.2521008403361, Blast_Score=139, Evalue=3e-33,
Organism=Drosophila melanogaster, GI28573065, Length=357, Percent_Identity=30.2521008403361, Blast_Score=139, Evalue=3e-33,
Organism=Drosophila melanogaster, GI18859735, Length=376, Percent_Identity=23.6702127659574, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI45551451, Length=371, Percent_Identity=26.6846361185984, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24641770, Length=371, Percent_Identity=26.6846361185984, Blast_Score=78, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24641760, Length=371, Percent_Identity=26.6846361185984, Blast_Score=78, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24641768, Length=371, Percent_Identity=26.6846361185984, Blast_Score=78, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24641766, Length=371, Percent_Identity=26.6846361185984, Blast_Score=78, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24641764, Length=371, Percent_Identity=26.6846361185984, Blast_Score=78, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43331; Mature: 43331

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLPLSKRVKGVAPSPTLAITAKAKQMKQEGIDVIGLGAGEPDFNTPQNIIDAAIESMNK
CCCCHHHHCCCCCCCCCEEEEHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHC
GFTKYTPSSGIIELKQAIVDKLQKDQFLNYETNQIFVGTGAKHVLYSAFQTILDPGDEVI
CCCEECCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCEE
IPVPYWVTYPEQVKLAGGIPVFVETGFDADFKISAANFEKAITKKTKAIVLNSPNNPSGM
EECCCEECCCHHEEECCCCEEEEECCCCCCEEEEHHHHHHHHHCCCEEEEEECCCCCCCE
CYTKEELIAIGEVAEKHQIYILSDEIYEKLYYGNKADLVSIASLSDRLYDLTIVINGVSK
EEEHHHHHHHHHHHCCCEEEEECHHHHHHHHCCCCCCEEEHHHHHCCEEEEEEEEECCHH
AYSMTGWRIGYAAANKEIIAGMSKLADHLTSNPTANAQYAALEAYVGSQEVPEKMYKAFE
HHHCCCCEEEEHHCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHH
ERMERFYPELSSIPGFKPKKPDGAFYFFIEVKEAAHKKGFQDVDAFVAALLEEAKVAVIP
HHHHHHCHHHHCCCCCCCCCCCCCEEEEEEEEHHHHHCCCHHHHHHHHHHHHCCCEEEEC
GSGFGMPDYIRLSYATNPDLFQEAINRIKSFMK
CCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MDLPLSKRVKGVAPSPTLAITAKAKQMKQEGIDVIGLGAGEPDFNTPQNIIDAAIESMNK
CCCCHHHHCCCCCCCCCEEEEHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHC
GFTKYTPSSGIIELKQAIVDKLQKDQFLNYETNQIFVGTGAKHVLYSAFQTILDPGDEVI
CCCEECCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCEE
IPVPYWVTYPEQVKLAGGIPVFVETGFDADFKISAANFEKAITKKTKAIVLNSPNNPSGM
EECCCEECCCHHEEECCCCEEEEECCCCCCEEEEHHHHHHHHHCCCEEEEEECCCCCCCE
CYTKEELIAIGEVAEKHQIYILSDEIYEKLYYGNKADLVSIASLSDRLYDLTIVINGVSK
EEEHHHHHHHHHHHCCCEEEEECHHHHHHHHCCCCCCEEEHHHHHCCEEEEEEEEECCHH
AYSMTGWRIGYAAANKEIIAGMSKLADHLTSNPTANAQYAALEAYVGSQEVPEKMYKAFE
HHHCCCCEEEEHHCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHH
ERMERFYPELSSIPGFKPKKPDGAFYFFIEVKEAAHKKGFQDVDAFVAALLEEAKVAVIP
HHHHHHCHHHHCCCCCCCCCCCCCEEEEEEEEHHHHHCCCHHHHHHHHHHHHCCCEEEEC
GSGFGMPDYIRLSYATNPDLFQEAINRIKSFMK
CCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1990006; 2155199 [H]