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The map label for this gene is xpt [H]

Identifier: 226224488

GI number: 226224488

Start: 1946027

End: 1946605

Strand: Reverse

Name: xpt [H]

Synonym: Lm4b_01901

Alternate gene names: 226224488

Gene position: 1946605-1946027 (Counterclockwise)

Preceding gene: 226224489

Following gene: 226224487

Centisome position: 66.83

GC content: 37.31

Gene sequence:

>579_bases
TTGAAATTACTGGAAGAGTTTATTCAAGAAAAAGGTACGGTTTTACCGGGGAATGTTTTAAAAGTAGATGCTTTTTTAAA
TCACCAAATTGATCCGGTTTTAATGCAAGCGATGGGAAATGAATTTGCTAAACGGTTCCAAGATTTAGGGATTACGAAAA
TTGTAACGATTGAATCATCGGGTATCGCACCCGCCGTTTTTGCAGGGCTCGCGCTTTCCGTACCAGTCGTGTTTGCACGC
AAGAAAAAATCAGTGACATTAACGGACAATTTATTCACAAGCACTGTCTATTCGTACACTAAAAAAGAATCGAATGATAT
TTCTGTATCAAAACAATTTTTAACAGTAGATGATACGATTTTAGTTATTGATGATTTTCTAGCAAATGGTCAGGCGGCAC
TCGGCTTACTTGAAATTGCAGAACATGCCGGAGCAAAAGTGGCGGGAATTGGTATTGTGATTGAAAAATCTTTCCAACAA
GGTCGCGAATTATTAAATAAAACAGGGATTCCAGTTTATTCACTAGCACGAATTGCCTCACTTGAAAACGAAGAAATCTT
ATTTTTAGAGGAGGAATAG

Upstream 100 bases:

>100_bases
GAGTAGTTTGTATAAAGAAGTCACTCCGAAAATTGGTGGCTTCTATACTGCTTCTCTATTTTTAGAGAAGCAGTTTTTTT
ATTTTGAAAGGAGAATCGTT

Downstream 100 bases:

>100_bases
GAGTAAATGTTAGGTAAAGGGAAAATTGCAGCTTTAGGATTTCAACATGTTCTAGCAATGTATGCAGGAGCAGTAATCGT
TCCACTATTAATTGGTGGAG

Product: xanthine phosphoribosyltransferase

Products: NA

Alternate protein names: XPRTase [H]

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MKLLEEFIQEKGTVLPGNVLKVDAFLNHQIDPVLMQAMGNEFAKRFQDLGITKIVTIESSGIAPAVFAGLALSVPVVFAR
KKKSVTLTDNLFTSTVYSYTKKESNDISVSKQFLTVDDTILVIDDFLANGQAALGLLEIAEHAGAKVAGIGIVIEKSFQQ
GRELLNKTGIPVYSLARIASLENEEILFLEEE

Sequences:

>Translated_192_residues
MKLLEEFIQEKGTVLPGNVLKVDAFLNHQIDPVLMQAMGNEFAKRFQDLGITKIVTIESSGIAPAVFAGLALSVPVVFAR
KKKSVTLTDNLFTSTVYSYTKKESNDISVSKQFLTVDDTILVIDDFLANGQAALGLLEIAEHAGAKVAGIGIVIEKSFQQ
GRELLNKTGIPVYSLARIASLENEEILFLEEE
>Mature_192_residues
MKLLEEFIQEKGTVLPGNVLKVDAFLNHQIDPVLMQAMGNEFAKRFQDLGITKIVTIESSGIAPAVFAGLALSVPVVFAR
KKKSVTLTDNLFTSTVYSYTKKESNDISVSKQFLTVDDTILVIDDFLANGQAALGLLEIAEHAGAKVAGIGIVIEKSFQQ
GRELLNKTGIPVYSLARIASLENEEILFLEEE

Specific function: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis [H]

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XPT subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836
- InterPro:   IPR010079 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.22 [H]

Molecular weight: Translated: 20944; Mature: 20944

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLEEFIQEKGTVLPGNVLKVDAFLNHQIDPVLMQAMGNEFAKRFQDLGITKIVTIESS
CHHHHHHHHHCCCCCCCCEEEEEHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECC
GIAPAVFAGLALSVPVVFARKKKSVTLTDNLFTSTVYSYTKKESNDISVSKQFLTVDDTI
CCCHHHHHHHHHHHHHHEECCCCCEEEEHHHHHHHHHHHHHCCCCCCEEEEEEEEECCEE
LVIDDFLANGQAALGLLEIAEHAGAKVAGIGIVIEKSFQQGRELLNKTGIPVYSLARIAS
EEEEHHHCCCHHHHHHHHHHHHCCCEEEEEEEEEEHHHHHHHHHHHHCCCCHHHHHHHHC
LENEEILFLEEE
CCCCEEEEEECC
>Mature Secondary Structure
MKLLEEFIQEKGTVLPGNVLKVDAFLNHQIDPVLMQAMGNEFAKRFQDLGITKIVTIESS
CHHHHHHHHHCCCCCCCCEEEEEHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECC
GIAPAVFAGLALSVPVVFARKKKSVTLTDNLFTSTVYSYTKKESNDISVSKQFLTVDDTI
CCCHHHHHHHHHHHHHHEECCCCCEEEEHHHHHHHHHHHHHCCCCCCEEEEEEEEECCEE
LVIDDFLANGQAALGLLEIAEHAGAKVAGIGIVIEKSFQQGRELLNKTGIPVYSLARIAS
EEEEHHHCCCHHHHHHHHHHHHCCCEEEEEEEEEEHHHHHHHHHHHHCCCCHHHHHHHHC
LENEEILFLEEE
CCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]