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The map label for this gene is lspA

Identifier: 226224447

GI number: 226224447

Start: 1906691

End: 1907155

Strand: Reverse

Name: lspA

Synonym: Lm4b_01860

Alternate gene names: 226224447

Gene position: 1907155-1906691 (Counterclockwise)

Preceding gene: 226224448

Following gene: 226224446

Centisome position: 65.48

GC content: 35.48

Gene sequence:

>465_bases
ATGTACTATTATCTAATCACCCTAGCAGTGATTGCGCTAGATCAATTAACTAAATGGATTGTTGTTCAAAATATGGAAAT
TGGACAGAAAATAGAAGTTATTCCTGGTTTCTTATACTGGACAAGCTACCGTAATGACGGGGCGGCTTGGAGTATTTTGG
AAGGACATATGTGGTTTTTCTATCTTATTACTGTTGTTGTTATTGGAATTATAATTTATATTATGCAAAAATATGCCAAA
GGAAAGCGACTATTTTCTATTAGTTTAGCGTTTATTCTAGGTGGTGCGATTGGTAATTTTATCGACCGAGTCTTGCATCA
AGAAGTAGTGGATTTTGTACAAACAGTATGGGGAAATTATTACTTCCCAATCTTTAATGTGGCAGATGCCGCGCTTTCAG
TTGGTGTCGTACTAATGCTCGTGTATGTTTTTGTAGACGACCGAAAAACGAAAGGAATTAAATAA

Upstream 100 bases:

>100_bases
TCAATTTATCATACAATAACAAAGAAGTGATGCGCTCTTCTTATTTTTAAAGGGGAGCGCGTACTTTTTATCTAACTGAT
GTGAAAAGAGGGTTCGGAAA

Downstream 100 bases:

>100_bases
TGCAGAATGAAACATTGATTATAGAAGAAAGTCATGCGCGTGAACGTGTGGATAAAGTGATTGCCGAAATGATGGGAAAA
AGTCGTTCAGCAATACAACT

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MYYYLITLAVIALDQLTKWIVVQNMEIGQKIEVIPGFLYWTSYRNDGAAWSILEGHMWFFYLITVVVIGIIIYIMQKYAK
GKRLFSISLAFILGGAIGNFIDRVLHQEVVDFVQTVWGNYYFPIFNVADAALSVGVVLMLVYVFVDDRKTKGIK

Sequences:

>Translated_154_residues
MYYYLITLAVIALDQLTKWIVVQNMEIGQKIEVIPGFLYWTSYRNDGAAWSILEGHMWFFYLITVVVIGIIIYIMQKYAK
GKRLFSISLAFILGGAIGNFIDRVLHQEVVDFVQTVWGNYYFPIFNVADAALSVGVVLMLVYVFVDDRKTKGIK
>Mature_154_residues
MYYYLITLAVIALDQLTKWIVVQNMEIGQKIEVIPGFLYWTSYRNDGAAWSILEGHMWFFYLITVVVIGIIIYIMQKYAK
GKRLFSISLAFILGGAIGNFIDRVLHQEVVDFVQTVWGNYYFPIFNVADAALSVGVVLMLVYVFVDDRKTKGIK

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

Organism=Escherichia coli, GI1786210, Length=147, Percent_Identity=33.3333333333333, Blast_Score=82, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 17707; Mature: 17707

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: PS00855 SPASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYYYLITLAVIALDQLTKWIVVQNMEIGQKIEVIPGFLYWTSYRNDGAAWSILEGHMWFF
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCHHHEEECCCCCCCEEHHHHHHHHHH
YLITVVVIGIIIYIMQKYAKGKRLFSISLAFILGGAIGNFIDRVLHQEVVDFVQTVWGNY
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
YFPIFNVADAALSVGVVLMLVYVFVDDRKTKGIK
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MYYYLITLAVIALDQLTKWIVVQNMEIGQKIEVIPGFLYWTSYRNDGAAWSILEGHMWFF
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCHHHEEECCCCCCCEEHHHHHHHHHH
YLITVVVIGIIIYIMQKYAKGKRLFSISLAFILGGAIGNFIDRVLHQEVVDFVQTVWGNY
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
YFPIFNVADAALSVGVVLMLVYVFVDDRKTKGIK
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]