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The map label for this gene is ftsY [H]

Identifier: 226224406

GI number: 226224406

Start: 1861827

End: 1862813

Strand: Reverse

Name: ftsY [H]

Synonym: Lm4b_01819

Alternate gene names: 226224406

Gene position: 1862813-1861827 (Counterclockwise)

Preceding gene: 226224407

Following gene: 226224405

Centisome position: 63.96

GC content: 40.93

Gene sequence:

>987_bases
ATGACCTTTTTTAAAAAATTAAAAGATAAAATAACTCAGCAAACTGATTCTGTTTCTGGAAAATTTAAAGATGGCTTATC
CAAAACACGCGGCAACTTTTCCGGAAAAATTAACGAAATGGTTGCTCGCTATCGTAAAGTCGACGAAGATTTCTTTGAAG
AACTAGAAGAAATCCTTATCGGAGCAGACGTTGGTTTTGAAACTGTCATGGAACTAGTCGATACGCTACGCCGTGAAGTT
CAACTTAGAAACATCAGTGATCCAAAAGACGTACAAGAAGTGATAGTCGAAAAATTAGTCGAGATTTACCAAGGAGACGA
AAAAGAAGACGAAGCACTTCATATCGAAGAAGACGGGCTAACCGTTATCTTGTTTGTTGGTGTGAATGGGGTTGGTAAAA
CAACCTCCATCGGAAAAATGGCTCATCGCTTTAAACAAGAAGGTAAAAAAGTGATGTTAGCTGCTGGCGATACATTCCGT
GCTGGTGCCATTGATCAATTAGAAGTCTGGGGCGAGCGTACCGGCGTCGATGTTATTAAACAAGCCGAGGGAAGCGACCC
TGCAGCGGTGATGTTTGATGCCGTTCAAGCAGCAAAAGCACGCAAAGCGGACGTTTTACTTTGCGATACAGCTGGCCGTT
TACAAAACAAAGTCAATCTAATGAACGAATTAGAAAAAGTAAAACGTGTCATTACGCGTGAAATTCCTAATGCGCCGCAC
GAAGTTTTACTAGTACTTGATGCTACAACTGGCCAAAATGCTTTCGTTCAAGCAAAACAATTTAAAGAAACAACCGACGT
AACAGGCATTATCCTCACAAAACTGGACGGAACTGCCAAGGGTGGTATTGTTATCGCCATTCGCAATGAACTAGATATTC
CAGTGAAATTCGTCGGTCTTGGGGAACAAATGGACGACCTACAAGCCTTTGATGCAAATGAATATGTGTATGGCTTATTT
GCTGATATGGTTGATAACGAAAAATAA

Upstream 100 bases:

>100_bases
TATTATACGGCGTCACCATGCAAGAGTCCGGCGTCTCCAAACTAGTATCAGTTCGTTTAGAAGAAACAGCTGAACTCATT
AAATAAAAGGAGTAAACAAA

Downstream 100 bases:

>100_bases
TCAGAGAAAGCCGAATGATTCTCGTCATTCTGGCTTTTTTCTCTTTTGTTTAACCTTCCTTGACATTCCCGCGATTTCCC
CGTATCCTTTAAAAGGAGAG

Product: SRP receptor alpha-subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MTFFKKLKDKITQQTDSVSGKFKDGLSKTRGNFSGKINEMVARYRKVDEDFFEELEEILIGADVGFETVMELVDTLRREV
QLRNISDPKDVQEVIVEKLVEIYQGDEKEDEALHIEEDGLTVILFVGVNGVGKTTSIGKMAHRFKQEGKKVMLAAGDTFR
AGAIDQLEVWGERTGVDVIKQAEGSDPAAVMFDAVQAAKARKADVLLCDTAGRLQNKVNLMNELEKVKRVITREIPNAPH
EVLLVLDATTGQNAFVQAKQFKETTDVTGIILTKLDGTAKGGIVIAIRNELDIPVKFVGLGEQMDDLQAFDANEYVYGLF
ADMVDNEK

Sequences:

>Translated_328_residues
MTFFKKLKDKITQQTDSVSGKFKDGLSKTRGNFSGKINEMVARYRKVDEDFFEELEEILIGADVGFETVMELVDTLRREV
QLRNISDPKDVQEVIVEKLVEIYQGDEKEDEALHIEEDGLTVILFVGVNGVGKTTSIGKMAHRFKQEGKKVMLAAGDTFR
AGAIDQLEVWGERTGVDVIKQAEGSDPAAVMFDAVQAAKARKADVLLCDTAGRLQNKVNLMNELEKVKRVITREIPNAPH
EVLLVLDATTGQNAFVQAKQFKETTDVTGIILTKLDGTAKGGIVIAIRNELDIPVKFVGLGEQMDDLQAFDANEYVYGLF
ADMVDNEK
>Mature_327_residues
TFFKKLKDKITQQTDSVSGKFKDGLSKTRGNFSGKINEMVARYRKVDEDFFEELEEILIGADVGFETVMELVDTLRREVQ
LRNISDPKDVQEVIVEKLVEIYQGDEKEDEALHIEEDGLTVILFVGVNGVGKTTSIGKMAHRFKQEGKKVMLAAGDTFRA
GAIDQLEVWGERTGVDVIKQAEGSDPAAVMFDAVQAAKARKADVLLCDTAGRLQNKVNLMNELEKVKRVITREIPNAPHE
VLLVLDATTGQNAFVQAKQFKETTDVTGIILTKLDGTAKGGIVIAIRNELDIPVKFVGLGEQMDDLQAFDANEYVYGLFA
DMVDNEK

Specific function: Required for normal cell growth and morphogenesis; translocation of at least 1 protein is impaired in its absence [H]

COG id: COG0552

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=275, Percent_Identity=30.1818181818182, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI226371618, Length=201, Percent_Identity=34.3283582089552, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI23308697, Length=304, Percent_Identity=29.6052631578947, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI295424842, Length=304, Percent_Identity=29.6052631578947, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI89061728, Length=135, Percent_Identity=32.5925925925926, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1789874, Length=303, Percent_Identity=50.4950495049505, Blast_Score=278, Evalue=3e-76,
Organism=Escherichia coli, GI1788963, Length=299, Percent_Identity=33.7792642140468, Blast_Score=153, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17539958, Length=281, Percent_Identity=29.5373665480427, Blast_Score=132, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI193206261, Length=322, Percent_Identity=29.8136645962733, Blast_Score=115, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6325345, Length=270, Percent_Identity=32.962962962963, Blast_Score=151, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6320498, Length=257, Percent_Identity=29.1828793774319, Blast_Score=86, Evalue=8e-18,
Organism=Drosophila melanogaster, GI17647949, Length=276, Percent_Identity=28.9855072463768, Blast_Score=131, Evalue=8e-31,
Organism=Drosophila melanogaster, GI24641198, Length=301, Percent_Identity=30.5647840531561, Blast_Score=115, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004390
- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N [H]

EC number: NA

Molecular weight: Translated: 36393; Mature: 36262

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFFKKLKDKITQQTDSVSGKFKDGLSKTRGNFSGKINEMVARYRKVDEDFFEELEEILI
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHH
GADVGFETVMELVDTLRREVQLRNISDPKDVQEVIVEKLVEIYQGDEKEDEALHIEEDGL
CCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCC
TVILFVGVNGVGKTTSIGKMAHRFKQEGKKVMLAAGDTFRAGAIDQLEVWGERTGVDVIK
EEEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHCCCCCHHHHH
QAEGSDPAAVMFDAVQAAKARKADVLLCDTAGRLQNKVNLMNELEKVKRVITREIPNAPH
HCCCCCCHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EVLLVLDATTGQNAFVQAKQFKETTDVTGIILTKLDGTAKGGIVIAIRNELDIPVKFVGL
CEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEEECCCCCCEEEEEC
GEQMDDLQAFDANEYVYGLFADMVDNEK
CCCHHHHHHCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TFFKKLKDKITQQTDSVSGKFKDGLSKTRGNFSGKINEMVARYRKVDEDFFEELEEILI
CHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHH
GADVGFETVMELVDTLRREVQLRNISDPKDVQEVIVEKLVEIYQGDEKEDEALHIEEDGL
CCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCC
TVILFVGVNGVGKTTSIGKMAHRFKQEGKKVMLAAGDTFRAGAIDQLEVWGERTGVDVIK
EEEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHCCCCCHHHHH
QAEGSDPAAVMFDAVQAAKARKADVLLCDTAGRLQNKVNLMNELEKVKRVITREIPNAPH
HCCCCCCHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EVLLVLDATTGQNAFVQAKQFKETTDVTGIILTKLDGTAKGGIVIAIRNELDIPVKFVGL
CEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEEECCCCCCEEEEEC
GEQMDDLQAFDANEYVYGLFADMVDNEK
CCCHHHHHHCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7584053; 9384377; 8654983 [H]