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The map label for this gene is suhB [H]

Identifier: 226223680

GI number: 226223680

Start: 1089616

End: 1090389

Strand: Direct

Name: suhB [H]

Synonym: Lm4b_01082

Alternate gene names: 226223680

Gene position: 1089616-1090389 (Clockwise)

Preceding gene: 226223677

Following gene: 226223681

Centisome position: 37.41

GC content: 39.28

Gene sequence:

>774_bases
ATGGACAGCGAAAAAATAGATTATTTAGCAAGGTTATGGATCATGGAAGCCGCAGCGAAAATTAAACAATCTTTCAAAGA
AACACTAGACATTGATGTCAAATCCGGTCGAAATGATTTAGTGACGAATATGGATAAAGAAACCGAAGCTTTTTTTGTTC
AACAAATTAAAGACCATTTTCCTGACCATCGTTTATTTGGTGAAGAAGGAATGGCGTCAGATGTAACAGATTTAGATGGA
GTGGTTTGGATTCTTGACCCAATTGACGGGACATTGAATTTTGTTGAACAGCAACGCGATTTTGCGATTTCACTTGCAGT
TTATGAAGATGGAATAGGGCAGCTTGCTTATATTTATGACGTTGCACGCGATGAGCTGTATTTTGGAGAAAAAGGAAAAG
GTGCTACAGTAAACGGCAGAACTATCCCTAAACTTGACCCAGCAATAGACCTAAAAGATACGCTATTAATTGCTAATTTG
AGCGTGACAAGAAAATTCCCAACCATGTGGGAGGCGGTAAAAGCTTCTAGAGGATTACGATTACACGGAGCAGCTTCACT
GGAATATATGGATGTTGCTACTGGACGAGCGGGAGCCTATCTTTCTGCTAATTTAGCCCCGTGGGATATAGCTGCTGGAA
AAATTATCGTCGAAGAATTAGGCGGGAAAGTGACACGGATTAATGGTGAAAAAATCAATATGTTAGAAAAAGGAAGTTCT
ATTGTAGCATCGCCAAAAATCCATCAAACCTTATTAGATAACTACCTGCCTTAA

Upstream 100 bases:

>100_bases
CATTATACGGAAGTTAAGTTCTAAGTGAAAGAATCTTGTTCTATTCAGATAATTCATTTTTGTGATAAAATAAACAAAAA
GAGTGCGAAGAGGTGTGTTT

Downstream 100 bases:

>100_bases
AGAAAGCGCTCAACATAAAAAAACTTGTTTTCAGAAAATAAAAATCGTGCCAAATCCGCTCAGCTATGCTATAATAGGTA
AGTTGATTTAAACGAGACGA

Product: extragenic suppressor protein SuhB and to myo-inositol-1(or 4)-monophosphatase

Products: NA

Alternate protein names: I-1-Pase; IMPase; Inositol-1-phosphatase [H]

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MDSEKIDYLARLWIMEAAAKIKQSFKETLDIDVKSGRNDLVTNMDKETEAFFVQQIKDHFPDHRLFGEEGMASDVTDLDG
VVWILDPIDGTLNFVEQQRDFAISLAVYEDGIGQLAYIYDVARDELYFGEKGKGATVNGRTIPKLDPAIDLKDTLLIANL
SVTRKFPTMWEAVKASRGLRLHGAASLEYMDVATGRAGAYLSANLAPWDIAAGKIIVEELGGKVTRINGEKINMLEKGSS
IVASPKIHQTLLDNYLP

Sequences:

>Translated_257_residues
MDSEKIDYLARLWIMEAAAKIKQSFKETLDIDVKSGRNDLVTNMDKETEAFFVQQIKDHFPDHRLFGEEGMASDVTDLDG
VVWILDPIDGTLNFVEQQRDFAISLAVYEDGIGQLAYIYDVARDELYFGEKGKGATVNGRTIPKLDPAIDLKDTLLIANL
SVTRKFPTMWEAVKASRGLRLHGAASLEYMDVATGRAGAYLSANLAPWDIAAGKIIVEELGGKVTRINGEKINMLEKGSS
IVASPKIHQTLLDNYLP
>Mature_257_residues
MDSEKIDYLARLWIMEAAAKIKQSFKETLDIDVKSGRNDLVTNMDKETEAFFVQQIKDHFPDHRLFGEEGMASDVTDLDG
VVWILDPIDGTLNFVEQQRDFAISLAVYEDGIGQLAYIYDVARDELYFGEKGKGATVNGRTIPKLDPAIDLKDTLLIANL
SVTRKFPTMWEAVKASRGLRLHGAASLEYMDVATGRAGAYLSANLAPWDIAAGKIIVEELGGKVTRINGEKINMLEKGSS
IVASPKIHQTLLDNYLP

Specific function: Unknown

COG id: COG0483

COG function: function code G; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI5031789, Length=244, Percent_Identity=29.5081967213115, Blast_Score=117, Evalue=9e-27,
Organism=Homo sapiens, GI221625487, Length=244, Percent_Identity=29.5081967213115, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI7657236, Length=231, Percent_Identity=29.4372294372294, Blast_Score=114, Evalue=9e-26,
Organism=Homo sapiens, GI221625507, Length=161, Percent_Identity=31.055900621118, Blast_Score=86, Evalue=3e-17,
Organism=Escherichia coli, GI1788882, Length=227, Percent_Identity=33.920704845815, Blast_Score=132, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI193202572, Length=245, Percent_Identity=29.7959183673469, Blast_Score=107, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI193202570, Length=247, Percent_Identity=29.1497975708502, Blast_Score=104, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6320493, Length=218, Percent_Identity=27.9816513761468, Blast_Score=86, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6321836, Length=247, Percent_Identity=27.5303643724696, Blast_Score=76, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24664926, Length=237, Percent_Identity=30.379746835443, Blast_Score=123, Evalue=1e-28,
Organism=Drosophila melanogaster, GI21357329, Length=261, Percent_Identity=31.0344827586207, Blast_Score=120, Evalue=9e-28,
Organism=Drosophila melanogaster, GI24664922, Length=240, Percent_Identity=30, Blast_Score=113, Evalue=1e-25,
Organism=Drosophila melanogaster, GI21357303, Length=239, Percent_Identity=30.5439330543933, Blast_Score=103, Evalue=8e-23,
Organism=Drosophila melanogaster, GI21357957, Length=236, Percent_Identity=26.271186440678, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24664918, Length=209, Percent_Identity=29.6650717703349, Blast_Score=93, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.25 [H]

Molecular weight: Translated: 28497; Mature: 28497

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSEKIDYLARLWIMEAAAKIKQSFKETLDIDVKSGRNDLVTNMDKETEAFFVQQIKDHF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCHHHHCCCCHHHHHHHHHHHHHC
PDHRLFGEEGMASDVTDLDGVVWILDPIDGTLNFVEQQRDFAISLAVYEDGIGQLAYIYD
CCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHCCCEEEEEEEEECCCCHHHHHHH
VARDELYFGEKGKGATVNGRTIPKLDPAIDLKDTLLIANLSVTRKFPTMWEAVKASRGLR
HHHHHEEECCCCCCCEECCCCCCCCCCCCCCCCEEEEEECHHHCCCHHHHHHHHHHCCEE
LHGAASLEYMDVATGRAGAYLSANLAPWDIAAGKIIVEELGGKVTRINGEKINMLEKGSS
EECCCCEEEEEECCCCCCCEEECCCCCCCCCCCCHHHHHHCCEEEEECCCEEEHHHCCCC
IVASPKIHQTLLDNYLP
EEECCHHHHHHHHHCCC
>Mature Secondary Structure
MDSEKIDYLARLWIMEAAAKIKQSFKETLDIDVKSGRNDLVTNMDKETEAFFVQQIKDHF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCHHHHCCCCHHHHHHHHHHHHHC
PDHRLFGEEGMASDVTDLDGVVWILDPIDGTLNFVEQQRDFAISLAVYEDGIGQLAYIYD
CCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHCCCEEEEEEEEECCCCHHHHHHH
VARDELYFGEKGKGATVNGRTIPKLDPAIDLKDTLLIANLSVTRKFPTMWEAVKASRGLR
HHHHHEEECCCCCCCEECCCCCCCCCCCCCCCCEEEEEECHHHCCCHHHHHHHHHHCCEE
LHGAASLEYMDVATGRAGAYLSANLAPWDIAAGKIIVEELGGKVTRINGEKINMLEKGSS
EECCCCEEEEEECCCCCCCEEECCCCCCCCCCCCHHHHHHCCEEEEECCCEEEHHHCCCC
IVASPKIHQTLLDNYLP
EEECCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969500; 9384377 [H]