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The map label for this gene is ykuT [H]

Identifier: 226223631

GI number: 226223631

Start: 1043656

End: 1044501

Strand: Reverse

Name: ykuT [H]

Synonym: Lm4b_01033

Alternate gene names: 226223631

Gene position: 1044501-1043656 (Counterclockwise)

Preceding gene: 226223644

Following gene: 226223624

Centisome position: 35.86

GC content: 38.65

Gene sequence:

>846_bases
ATGAATTTACTCAAAAAGTGGTTCAGTTCTATTGACTGGGACCAATTTTGGAATCATATTATTTCAGTAGGAATAAAAAT
CGCCATTTTAATTGCTCTTTATTTTATTTTCCGCGTGGTTGGGAATAAAATTATCCGTAGTTTCTTCCGCAAATATCGGC
AACAACAAGCAGTTTCTGTTGGGCGCGCGGACACGTTAGAAAGCTTGATTTCTAATTTTTACGGCTATGTTTTATTCTTC
ACTTTTGCGATTTTATTATTACAGAACTTTATGGATGTTACAGCGATTATTGCAAGTGCTGGGGTGGCGAGTTTGGCTAT
TGCCTTTGGTGCGCAAGGACTTGTTAGTGACGTTGTGACTGGATTTTTTATTTTACTTGAACGTCAACTTGATGTTGGTG
ATACGATTACCATTGGACTAGTTAATGGAACAGTAGAAGCACTTGGACTTAGAACAACACAGGTACGTGATTTTGATGGC
ACGCTTCATTTCATTCCTAACAGGCAAATTATGGTCGTTAGTAATCATTCGCGCGGTAATATGCGTGTGATGGTGGACAT
TCAAATTAGTCCACATGAAGATCCGGAAAAAGCAATTAAAATTATTGGTGAGGTTTGTGACGTAGCTGCAAAAGAAAATA
AAAATATCGTTGAGCCCCCTGTTGTATTAGGTGTGCAAAACATTGACGCAACAAACATGATTATCCGCGTAGTCGGTAAA
GCAGTGAACGGCGAGCAGTATTCTGTTCAACGTGACTTACTCAAAGATATTCGCGAAGCACTCGCAGAAAACGAAATCGA
GTTACCACTTAATTTTGTCAGCACCTTCGGACCAAATAATAATTAA

Upstream 100 bases:

>100_bases
AGCATTTTTATAAAATATTTGTTAGAATAGAAAAGGACATTTCATTTAGGAAGGGGGAGATGAAATGGATGGAGAACTTT
CAAAGGATGTGGACCAGAAG

Downstream 100 bases:

>100_bases
AAAGACGCCAATTCGCTCCTTTTGAGAACGAATTGACGTCTTTTTATTTACTTTCCAAAAAGTGGATTAATACATCAATT
GCAAATGGAATAGCTTCTTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MNLLKKWFSSIDWDQFWNHIISVGIKIAILIALYFIFRVVGNKIIRSFFRKYRQQQAVSVGRADTLESLISNFYGYVLFF
TFAILLLQNFMDVTAIIASAGVASLAIAFGAQGLVSDVVTGFFILLERQLDVGDTITIGLVNGTVEALGLRTTQVRDFDG
TLHFIPNRQIMVVSNHSRGNMRVMVDIQISPHEDPEKAIKIIGEVCDVAAKENKNIVEPPVVLGVQNIDATNMIIRVVGK
AVNGEQYSVQRDLLKDIREALAENEIELPLNFVSTFGPNNN

Sequences:

>Translated_281_residues
MNLLKKWFSSIDWDQFWNHIISVGIKIAILIALYFIFRVVGNKIIRSFFRKYRQQQAVSVGRADTLESLISNFYGYVLFF
TFAILLLQNFMDVTAIIASAGVASLAIAFGAQGLVSDVVTGFFILLERQLDVGDTITIGLVNGTVEALGLRTTQVRDFDG
TLHFIPNRQIMVVSNHSRGNMRVMVDIQISPHEDPEKAIKIIGEVCDVAAKENKNIVEPPVVLGVQNIDATNMIIRVVGK
AVNGEQYSVQRDLLKDIREALAENEIELPLNFVSTFGPNNN
>Mature_281_residues
MNLLKKWFSSIDWDQFWNHIISVGIKIAILIALYFIFRVVGNKIIRSFFRKYRQQQAVSVGRADTLESLISNFYGYVLFF
TFAILLLQNFMDVTAIIASAGVASLAIAFGAQGLVSDVVTGFFILLERQLDVGDTITIGLVNGTVEALGLRTTQVRDFDG
TLHFIPNRQIMVVSNHSRGNMRVMVDIQISPHEDPEKAIKIIGEVCDVAAKENKNIVEPPVVLGVQNIDATNMIIRVVGK
AVNGEQYSVQRDLLKDIREALAENEIELPLNFVSTFGPNNN

Specific function: May play a role in resistance to osmotic downshock [H]

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI87081787, Length=267, Percent_Identity=28.8389513108614, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1786670, Length=182, Percent_Identity=25.8241758241758, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 31332; Mature: 31332

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLLKKWFSSIDWDQFWNHIISVGIKIAILIALYFIFRVVGNKIIRSFFRKYRQQQAVSV
CCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GRADTLESLISNFYGYVLFFTFAILLLQNFMDVTAIIASAGVASLAIAFGAQGLVSDVVT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
GFFILLERQLDVGDTITIGLVNGTVEALGLRTTQVRDFDGTLHFIPNRQIMVVSNHSRGN
HHHHHHHHCCCCCCEEEEEEECCHHHHHCCCHHEEECCCCEEEEECCCEEEEEECCCCCC
MRVMVDIQISPHEDPEKAIKIIGEVCDVAAKENKNIVEPPVVLGVQNIDATNMIIRVVGK
EEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHHHHH
AVNGEQYSVQRDLLKDIREALAENEIELPLNFVSTFGPNNN
HCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCC
>Mature Secondary Structure
MNLLKKWFSSIDWDQFWNHIISVGIKIAILIALYFIFRVVGNKIIRSFFRKYRQQQAVSV
CCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GRADTLESLISNFYGYVLFFTFAILLLQNFMDVTAIIASAGVASLAIAFGAQGLVSDVVT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
GFFILLERQLDVGDTITIGLVNGTVEALGLRTTQVRDFDGTLHFIPNRQIMVVSNHSRGN
HHHHHHHHCCCCCCEEEEEEECCHHHHHCCCHHEEECCCCEEEEECCCEEEEEECCCCCC
MRVMVDIQISPHEDPEKAIKIIGEVCDVAAKENKNIVEPPVVLGVQNIDATNMIIRVVGK
EEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHHHHH
AVNGEQYSVQRDLLKDIREALAENEIELPLNFVSTFGPNNN
HCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]