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The map label for this gene is patA [H]

Identifier: 226223624

GI number: 226223624

Start: 1038022

End: 1039167

Strand: Reverse

Name: patA [H]

Synonym: Lm4b_01026

Alternate gene names: 226223624

Gene position: 1039167-1038022 (Counterclockwise)

Preceding gene: 226223631

Following gene: 226223619

Centisome position: 35.68

GC content: 40.05

Gene sequence:

>1146_bases
ATGACAAAATCTATTCGACCAGAATTACGCGATATTCAAGTAAGTGGTATCAGAACTTTTAATACACGAGTGACGGGTAT
TCCTGATATGATCCGTTTAACACTTGGCGAACCTGACTTTCCAACGCCTGAGCATGTCAAACAAGCGGCCATTTCAGCAA
TAGAAGAAAATTTCACCAACTATACACCCAATGCCGGGATGCCAGAATTACTCGAAGCAGCTTCCACTTATTTTCATGAA
AAATATGACTTGTCCTATAATAATAAAGAAATTATCGTTACGGTCGGCGCTACAGAGGCTATCTCCGTTGCCTTGCAAAC
GATTTTGGAGCCTGGGGATGAAGTTATCTTACCAGACCCTATTTATCCAGGTTACGAGCCTCTAATTACGTTAAATAGAG
CGCACCCGGTTAAAGTTGATACGACCGAAACTAATTTCAAATTAACACCTGAACAATTACGAGCACATATCACGCCAAAA
ACTAAAGCACTTATCATTCCTTATCCATCCAATCCGACCGGTGTTACACTCTCTAAAAAAGAACTTTTCGCATTAGCAGA
AGTACTAAAAGAAACAGGTATTTTTGTCATTGCTGATGAGATTTACAGTGAATTAACTTATCACGAGGAGCACGTGAGCA
TTGCGCCTTTACTAAGAGAGCAGACAATCGTTATCAACGGTTTATCAAAATCTCACGCAATGATTGGTTGGCGAATTGGC
TTTTTACTTGCACCAGAAGCCCTTACACAAGAAATGTTGAAAATCCATCAATATTCGGTTACTTGCGCAAGTTCCATTTC
CCAAAAAGCAGCACTAGAAGCTCTTACTAACGGCAAAGACGATGCTTTTCAAATGCGAACTGAATACAAAACACGCGCTA
ATTTCACTCAAGATCGACTAGAAAAAATGGGCTTTACTGTCATCCCGCCAGATGGTGCATTTTACTTCTTCGTCAAACTT
CCCGATGAAATAACCGAAAATGCTTTCGATTGGGCTGTAAAACTTGCTGAAGAAGCCAAGGTTGCAGTTGTTCCTGGAAA
TGCTTTTTCCGAAAAAGGCGATCGTTACTTCCGTCTTTCTTATGCTACTTCCTTTAATAATCTTGCTGAAGCATTAGATC
GAATGGCTCAGTTTATAGCAAAATAA

Upstream 100 bases:

>100_bases
ATTTTGCTTTTCTTCCTTTTTAAGCTATAATGGAATGAAATCACGAAGCTTACTCCCACCTGATTTTCACGGGATTTTCT
TATAAAGAAAGGTGACGAAA

Downstream 100 bases:

>100_bases
AAAAACATCCACTAACTTAAATTAGTGGATGTTTTTTTAACGATAATATTTAATGAGCGCTTGCGTCCCTTCTTCACTCA
AACCTTGTTCAGCTAGCGTT

Product: aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 380

Protein sequence:

>381_residues
MTKSIRPELRDIQVSGIRTFNTRVTGIPDMIRLTLGEPDFPTPEHVKQAAISAIEENFTNYTPNAGMPELLEAASTYFHE
KYDLSYNNKEIIVTVGATEAISVALQTILEPGDEVILPDPIYPGYEPLITLNRAHPVKVDTTETNFKLTPEQLRAHITPK
TKALIIPYPSNPTGVTLSKKELFALAEVLKETGIFVIADEIYSELTYHEEHVSIAPLLREQTIVINGLSKSHAMIGWRIG
FLLAPEALTQEMLKIHQYSVTCASSISQKAALEALTNGKDDAFQMRTEYKTRANFTQDRLEKMGFTVIPPDGAFYFFVKL
PDEITENAFDWAVKLAEEAKVAVVPGNAFSEKGDRYFRLSYATSFNNLAEALDRMAQFIAK

Sequences:

>Translated_381_residues
MTKSIRPELRDIQVSGIRTFNTRVTGIPDMIRLTLGEPDFPTPEHVKQAAISAIEENFTNYTPNAGMPELLEAASTYFHE
KYDLSYNNKEIIVTVGATEAISVALQTILEPGDEVILPDPIYPGYEPLITLNRAHPVKVDTTETNFKLTPEQLRAHITPK
TKALIIPYPSNPTGVTLSKKELFALAEVLKETGIFVIADEIYSELTYHEEHVSIAPLLREQTIVINGLSKSHAMIGWRIG
FLLAPEALTQEMLKIHQYSVTCASSISQKAALEALTNGKDDAFQMRTEYKTRANFTQDRLEKMGFTVIPPDGAFYFFVKL
PDEITENAFDWAVKLAEEAKVAVVPGNAFSEKGDRYFRLSYATSFNNLAEALDRMAQFIAK
>Mature_380_residues
TKSIRPELRDIQVSGIRTFNTRVTGIPDMIRLTLGEPDFPTPEHVKQAAISAIEENFTNYTPNAGMPELLEAASTYFHEK
YDLSYNNKEIIVTVGATEAISVALQTILEPGDEVILPDPIYPGYEPLITLNRAHPVKVDTTETNFKLTPEQLRAHITPKT
KALIIPYPSNPTGVTLSKKELFALAEVLKETGIFVIADEIYSELTYHEEHVSIAPLLREQTIVINGLSKSHAMIGWRIGF
LLAPEALTQEMLKIHQYSVTCASSISQKAALEALTNGKDDAFQMRTEYKTRANFTQDRLEKMGFTVIPPDGAFYFFVKLP
DEITENAFDWAVKLAEEAKVAVVPGNAFSEKGDRYFRLSYATSFNNLAEALDRMAQFIAK

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=361, Percent_Identity=29.0858725761773, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI56713256, Length=361, Percent_Identity=29.0858725761773, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI95147551, Length=320, Percent_Identity=28.125, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI169881279, Length=320, Percent_Identity=28.125, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI4507369, Length=384, Percent_Identity=25, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI169881281, Length=231, Percent_Identity=26.8398268398268, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI7705897, Length=361, Percent_Identity=25.7617728531856, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI33469970, Length=361, Percent_Identity=25.7617728531856, Blast_Score=76, Evalue=6e-14,
Organism=Escherichia coli, GI1786816, Length=354, Percent_Identity=25.7062146892655, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI1788722, Length=358, Percent_Identity=28.2122905027933, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI1788627, Length=373, Percent_Identity=26.8096514745308, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1787710, Length=303, Percent_Identity=26.7326732673267, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1787909, Length=348, Percent_Identity=21.264367816092, Blast_Score=72, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71994472, Length=370, Percent_Identity=28.6486486486486, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI71994476, Length=370, Percent_Identity=28.6486486486486, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17567663, Length=373, Percent_Identity=26.5415549597855, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17567369, Length=374, Percent_Identity=27.2727272727273, Blast_Score=117, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6322401, Length=355, Percent_Identity=27.0422535211268, Blast_Score=121, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6320317, Length=324, Percent_Identity=22.8395061728395, Blast_Score=66, Evalue=9e-12,
Organism=Drosophila melanogaster, GI28573069, Length=388, Percent_Identity=25.5154639175258, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24646114, Length=388, Percent_Identity=25.5154639175258, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI28573067, Length=388, Percent_Identity=25.5154639175258, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI28573065, Length=388, Percent_Identity=25.5154639175258, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI18859735, Length=376, Percent_Identity=22.6063829787234, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI45551451, Length=435, Percent_Identity=25.0574712643678, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24641770, Length=435, Percent_Identity=25.0574712643678, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24641760, Length=435, Percent_Identity=25.0574712643678, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24641768, Length=435, Percent_Identity=25.0574712643678, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24641766, Length=435, Percent_Identity=25.0574712643678, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24641764, Length=435, Percent_Identity=25.0574712643678, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.-

Molecular weight: Translated: 42596; Mature: 42465

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKSIRPELRDIQVSGIRTFNTRVTGIPDMIRLTLGEPDFPTPEHVKQAAISAIEENFTN
CCCCCCCCHHEEEEECEEEECCEECCCCHHEEEEECCCCCCCHHHHHHHHHHHHHHHCCC
YTPNAGMPELLEAASTYFHEKYDLSYNNKEIIVTVGATEAISVALQTILEPGDEVILPDP
CCCCCCCHHHHHHHHHHHHHEECCCCCCCEEEEEECCHHHHHHHHHHHHCCCCCEEECCC
IYPGYEPLITLNRAHPVKVDTTETNFKLTPEQLRAHITPKTKALIIPYPSNPTGVTLSKK
CCCCCCCEEEECCCCCEEEECCCCCEEECHHHHHEECCCCCCEEEEECCCCCCCEEECHH
ELFALAEVLKETGIFVIADEIYSELTYHEEHVSIAPLLREQTIVINGLSKSHAMIGWRIG
HHHHHHHHHHHCCEEEEEHHHHHHHHHCHHHCCHHHHHCCCEEEEECCCCCCEEEEEEEE
FLLAPEALTQEMLKIHQYSVTCASSISQKAALEALTNGKDDAFQMRTEYKTRANFTQDRL
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHH
EKMGFTVIPPDGAFYFFVKLPDEITENAFDWAVKLAEEAKVAVVPGNAFSEKGDRYFRLS
HHCCCEEECCCCCEEEEEECCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEEE
YATSFNNLAEALDRMAQFIAK
EHHCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TKSIRPELRDIQVSGIRTFNTRVTGIPDMIRLTLGEPDFPTPEHVKQAAISAIEENFTN
CCCCCCCHHEEEEECEEEECCEECCCCHHEEEEECCCCCCCHHHHHHHHHHHHHHHCCC
YTPNAGMPELLEAASTYFHEKYDLSYNNKEIIVTVGATEAISVALQTILEPGDEVILPDP
CCCCCCCHHHHHHHHHHHHHEECCCCCCCEEEEEECCHHHHHHHHHHHHCCCCCEEECCC
IYPGYEPLITLNRAHPVKVDTTETNFKLTPEQLRAHITPKTKALIIPYPSNPTGVTLSKK
CCCCCCCEEEECCCCCEEEECCCCCEEECHHHHHEECCCCCCEEEEECCCCCCCEEECHH
ELFALAEVLKETGIFVIADEIYSELTYHEEHVSIAPLLREQTIVINGLSKSHAMIGWRIG
HHHHHHHHHHHCCEEEEEHHHHHHHHHCHHHCCHHHHHCCCEEEEECCCCCCEEEEEEEE
FLLAPEALTQEMLKIHQYSVTCASSISQKAALEALTNGKDDAFQMRTEYKTRANFTQDRL
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHH
EKMGFTVIPPDGAFYFFVKLPDEITENAFDWAVKLAEEAKVAVVPGNAFSEKGDRYFRLS
HHCCCEEECCCCCEEEEEECCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEEE
YATSFNNLAEALDRMAQFIAK
EHHCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 2104615 [H]